{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:20:41Z","timestamp":1787008841900,"version":"build-2736575974"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T00:00:00Z","timestamp":1570147200000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG032052-03"],"award-info":[{"award-number":["R01 AG032052-03"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["1 UL1 RR025758-01"],"award-info":[{"award-number":["1 UL1 RR025758-01"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["4K24HD070966-05"],"award-info":[{"award-number":["4K24HD070966-05"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006663","name":"National Institute on Disability and Rehabilitation Research","doi-asserted-by":"publisher","award":["H133P120001"],"award-info":[{"award-number":["H133P120001"]}],"id":[{"id":"10.13039\/100006663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Late-Life Function and Disability Instrument (LLFDI) is a well-validated and frequently used patient-reported outcome for older adults. The aim of this study was to estimate the minimal clinically important difference (MCID) of the LLFDI-Function Component (LLFDI-FC) and its subscales among community-dwelling older adults with mobility limitations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a secondary analysis of the Boston Rehabilitative Impairment Study of the Elderly, a longitudinal cohort study of older adults with mobility limitations residing in the community. The MCID for each LLFDI-FC scale over 1 year of follow-up was estimated using both anchor- and distribution-based methods, including mean change scores on a patient-reported global rating of change in function scale, the standard error of measurement (SEM), and the minimal detectable change with 90% confidence (MDC90).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Data from 320 older adults were used in the analysis (mean age 76 years, 69% female, mean of four chronic conditions). Meaningful change estimates for \u201csmall change\u201d based on the global rating of change and SEM were 2, 3, 4, and 4 points for the LLFDI-FC overall function scale and basic lower-extremity, advanced lower-extremity, and upper-extremity subscales, respectively. Estimates for \u201csubstantial change\u201d based on the global rating of change and minimal detectable change with 90% confidence were 5, 6, 9, and 10 points for the overall function scale and basic lower-extremity, advanced lower-extremity, and upper-extremity subscales, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study provides the first MCID estimates for the LLFDI-FC, a widely used patient-reported measure of function. These values can be used to interpret the outcomes of longitudinal investigations of functional status in similar populations of community-dwelling older adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/gerona\/gly230","type":"journal-article","created":{"date-parts":[[2018,10,4]],"date-time":"2018-10-04T03:03:28Z","timestamp":1538622208000},"page":"556-559","source":"Crossref","is-referenced-by-count":27,"title":["Meaningful Change Estimates for the Late-Life Function and Disability Instrument in Older Adults"],"prefix":"10.1093","volume":"74","author":[{"given":"Marla K","family":"Beauchamp","sequence":"first","affiliation":[{"name":"School of Rehabilitation Science, Ontario, Canada"},{"name":"Department of Medicine, McMaster University, Hamilton, Ontario, Canada"},{"name":"Respiratory Research, West Park Healthcare Centre, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel E","family":"Ward","sequence":"first","affiliation":[{"name":"New England Geriatric Research Education and Clinical Center, Veterans Administration Boston Health System, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan M","family":"Jette","sequence":"first","affiliation":[{"name":"Health and Disability Research Institute, Boston University School of Health, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan F","family":"Bean","sequence":"first","affiliation":[{"name":"New England Geriatric Research Education and Clinical Center, Veterans Administration Boston Health System, Massachusetts"},{"name":"Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts"},{"name":"Spaulding Rehabilitation Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,10,4]]},"reference":[{"key":"2020030521302920600_CIT0001","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1093\/gerona\/glu227","article-title":"Predictive validity and responsiveness of patient-reported and performance-based measures of function in the Boston RISE study","volume":"70","author":"Beauchamp","year":"2015","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2020030521302920600_CIT0002","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/S0895-4356(01)00357-2","article-title":"Self-reported preclinical disability identifies older women with early declines in performance and early disease","volume":"54","author":"Fried","year":"2001","journal-title":"J Clin Epidemiol"},{"key":"2020030521302920600_CIT0003","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1056\/NEJM199503023320902","article-title":"Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability","volume":"332","author":"Guralnik","year":"1995","journal-title":"N Engl J Med"},{"key":"2020030521302920600_CIT0004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0277-9536(94)90294-1","article-title":"The disablement process","volume":"38","author":"Verbrugge","year":"1994","journal-title":"Soc Sci Med"},{"key":"2020030521302920600_CIT0005","doi-asserted-by":"crossref","first-page":"M217","DOI":"10.1093\/gerona\/57.4.M217","article-title":"Late life function and disability instrument: II. 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