{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T13:07:12Z","timestamp":1789391232468,"version":"build-2803163510"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T00:00:00Z","timestamp":1560211200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K24AG045334"],"award-info":[{"award-number":["K24AG045334"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K23AG057832"],"award-info":[{"award-number":["K23AG057832"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,2,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Age-related hearing loss (HL), a common and treatable condition, has been associated with other age-related conditions. Late life cognitive impairment is a major public health concern that is rarely treatable. Studies examining the relationship between HL and cognition have been limited by non-Hispanic cohorts, small samples, or limited confounding control. We overcome these limitations in a large Hispanic cohort.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a multisite cross-sectional study of 5,277 subjects at least 50 years old (Hispanic Community Health Study, HCHS). The main exposure was audiometric HL. The main outcome measure was neurocognitive performance ascertained by the Digit Symbol Substitution Test (DSST), Word Frequency Test, Spanish-English Verbal Learning Test (SEVLT), and Six-Item Screener.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The mean age was 58.4 years (SD = 6.2). A 20-dB (equivalent to a one-category worsening) increase in HL was associated with a \u22121.53 (95% CI, \u22122.11, \u22120.94) raw score point difference in the DSST, adjusting for demographics, hearing aid use, and cardiovascular disease. Similarly, a 20-dB increase in HL was associated with a \u22120.86 (\u22121.23, \u22120.49) point difference on the Word Frequency Test, \u22120.76 (\u22121.04, \u22120.47) on the SEVLT 3 trials, \u22120.45 (\u22120.60, \u22120.29) on the SELVT recall, and \u22120.07 (\u22120.12, \u22120.02) on the Six-Item Screener.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>In the largest study of formal, audiometric HL and cognition to date, HL was independently associated with worse performance in a range of neurocognitive measures. Because HL is common and potentially treatable, it should be investigated as a modifiable risk factor for neurocognitive decline and dementia.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gerona\/glz119","type":"journal-article","created":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T05:09:41Z","timestamp":1560229781000},"page":"552-560","source":"Crossref","is-referenced-by-count":44,"title":["Audiometric Age-Related Hearing Loss and Cognition in the Hispanic Community Health Study"],"prefix":"10.1093","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2432-5291","authenticated-orcid":false,"given":"Justin S","family":"Golub","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Columbia University Irving Medical Center, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam M","family":"Brickman","sequence":"first","affiliation":[{"name":"Department of Neurology, the Taub Institute for Research on Alzheimer\u2019s Disease and the Aging Brain, and the Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, NewYork-Presbyterian\/Columbia University Irving Medical Center, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam J","family":"Ciarleglio","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Milken Institute School of Public Health, George Washington University, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Schupf","sequence":"first","affiliation":[{"name":"Department of Neurology, the Taub Institute for Research on Alzheimer\u2019s Disease and the Aging Brain, and the Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, NewYork-Presbyterian\/Columbia University Irving Medical Center, New York"},{"name":"Department of Epidemiology, Joseph P. 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