{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T09:00:32Z","timestamp":1768640432794,"version":"3.49.0"},"reference-count":46,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T00:00:00Z","timestamp":1703203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R21-AG051853"],"award-info":[{"award-number":["R21-AG051853"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["S10OD020039"],"award-info":[{"award-number":["S10OD020039"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32 NS007292"],"award-info":[{"award-number":["T32 NS007292"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Older adults show memory benefits for self-relevant and emotional content, but there are individual differences in this effect. It has been debated whether processing of self-relevant and emotional information relies on similar processes to one another. We examined whether variation in frontal lobe (FL) function among older adults related similarly to the processing of self-relevant information as it did to emotional information, or whether these relations diverged.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>While undergoing fMRI, participants (ages 60\u201388) viewed positive, negative, and neutral objects, and imagined placing those objects in either their home or a stranger\u2019s home. Participants completed a surprise memory test outside of the MRI. In a separate session, a cognitive battery was collected and composite scores measuring FL and medial temporal lobe function were computed and related to the behavioral memory performance and the neural engagement during fMRI.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Behaviorally, FL function related to memory for self-relevant, but not emotional content. Older adults with higher FL function demonstrated reduced self-bias in memory performance. During the processing of self-relevant stimuli, independent of emotion, levels of activity in the middle frontal gyrus showed positive associations with FL function. This relationship was not driven by compensatory activity or disruptions to nonself-relevant neutral content.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>These findings point to divergence in the cognitive functions relating to memory enhancements for self- and emotional-relevance. The results further suggest self-relevance as a mnemonic device for older adults, especially in those with lower FL function.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/geronb\/gbad186","type":"journal-article","created":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T18:58:42Z","timestamp":1703271522000},"source":"Crossref","is-referenced-by-count":4,"title":["Individual Differences in Older Adult Frontal Lobe Function Relate to Memory and Neural Activity for Self-Relevant and Emotional Content"],"prefix":"10.1093","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6779-1658","authenticated-orcid":false,"given":"Ryan T","family":"Daley","sequence":"first","affiliation":[{"name":"Department of Psychology, Gordon College , Wenham, Massachusetts , USA"},{"name":"Department of Psychology and Neuroscience, Boston College , Chestnut Hill, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3855-8961","authenticated-orcid":false,"given":"Holly J","family":"Bowen","sequence":"additional","affiliation":[{"name":"Department of Psychology, Southern Methodist University , Dallas, Texas , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4316-7823","authenticated-orcid":false,"given":"Eric C","family":"Fields","sequence":"additional","affiliation":[{"name":"Department of Psychology and Neuroscience, Boston College , Chestnut Hill, Massachusetts , USA"},{"name":"Department of Psychology, Westminster College , New Wilmington , Pennsylvania , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katelyn R","family":"Parisi","sequence":"additional","affiliation":[{"name":"Department of Psychology and Neuroscience, Boston College , Chestnut Hill, Massachusetts , USA"},{"name":"Department of Psychology, Brandeis University , Waltham, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Gutchess","sequence":"additional","affiliation":[{"name":"Department of Psychology, Brandeis University , Waltham, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A","family":"Kensinger","sequence":"additional","affiliation":[{"name":"Department of Psychology and Neuroscience, Boston College , Chestnut Hill, Massachusetts , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,12,22]]},"reference":[{"key":"2024021710242333700_CIT0001","first-page":"1195","article-title":"Dorsolateral prefrontal contributions to human working memory","volume-title":"Cortex","author":"Barbey","year":"2013"},{"key":"2024021710242333700_CIT0002","first-page":"48","article-title":"Direct comparison of prefrontal cortex regions engaged by working and long-term memory tasks","volume-title":"Neuroimage","author":"Braver","year":"2001"},{"key":"2024021710242333700_CIT0003","first-page":"921","article-title":"Age differences in veridical and false recall are not inevitable: The role of frontal lobe function","volume-title":"Psychonomic Bulletin & Review","author":"Butler","year":"2004"},{"key":"2024021710242333700_CIT0004","first-page":"1","article-title":"Age differences in ventromedial prefrontal cortex functional connectivity during socioemotional content processing","volume-title":"Social Behavior and Personality: An International Journal","author":"Daley","year":"2020"},{"key":"2024021710242333700_CIT0005","first-page":"405","article-title":"Neural mechanisms supporting emotional and self-referential information processing and encoding in older and younger adults","volume-title":"Social Cognitive and Affective Neuroscience","author":"Daley","year":"2020"},{"key":"2024021710242333700_CIT0006","first-page":"196","article-title":"Flashbulb memories for September 11th can be preserved in older adults","volume-title":"Neuropsychology, Development, and Cognition. 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