{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:20:56Z","timestamp":1787008856432,"version":"build-2736575974"},"reference-count":61,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Aerobic exercise is a cost-effective intervention to improve arterial stiffness, but its effects on older people are unclear; this review aims to determine those effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research Design and Methods<\/jats:title>\n                    <jats:p>Five databases were searched for randomized controlled trials of aerobic exercises. Backward and forward citations and clinical trial registries were also reviewed. Data were extracted and synthesized. A random-effects model was used in a meta-analysis. The risk of bias and the certainty of the evidence were also assessed. The protocol of this review was registered (PROSPERO registration number: CRD42022349494).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighteen studies (n\u2005=\u2005775) were identified. Aerobic exercises included cycling, walking, swimming, standing core exercise, bench step exercise, aquarobic exercise, jogging, running, upper-limb cycling, and aquatic walking. Postintervention, improvements were seen in the pulse wave velocity (SMD9\u2005=\u2005\u22120.89, 95% confidence interval (CI)\u20131.57 to \u20130.22), arterial velocity\u2013pulse index (MD2\u2005=\u2005\u20136.84, 95% CI \u20139.05 to \u20134.63), and arterial pressure\u2013volume index (MD2\u2005=\u2005\u20134.97, 95% CI \u20136.9 to \u20133.04), but not in the augmentation index, arterial compliance, or beta stiffness index. Exercise lasting &amp;gt;8 weeks but not 4\u20138 weeks significantly improved pulse wave velocity. Aerobic exercise had a beneficial effect on healthy older people but not on older people with disease. The overall risk of bias was high in 9 of the included studies, with some concerns in the remaining studies. The certainty of the evidence was very low.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion and Implications<\/jats:title>\n                    <jats:p>Aerobic exercises, particularly those lasting &amp;gt;8 weeks, appear to be effective at improving pulse wave velocity in older people postintervention. Future trials with robust designs are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/geront\/gnad123","type":"journal-article","created":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T09:49:42Z","timestamp":1693388982000},"source":"Crossref","is-referenced-by-count":18,"title":["The Effect of Aerobic Exercises on Arterial Stiffness in Older People: A Systematic Review and Meta-Analysis"],"prefix":"10.1093","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8967-8763","authenticated-orcid":false,"given":"Lily Yuen Wah","family":"Ho","sequence":"first","affiliation":[{"name":"School of Nursing, The Hong Kong Polytechnic University , Hong Kong SAR , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4332-780X","authenticated-orcid":false,"given":"Rick Yiu Cho","family":"Kwan","sequence":"additional","affiliation":[{"name":"School of Nursing, Tung Wah College , Hong Kong SAR , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka Man","family":"Yuen","sequence":"additional","affiliation":[{"name":"School of Nursing, The Hong Kong Polytechnic University , Hong Kong SAR , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai Chun","family":"Leung","sequence":"additional","affiliation":[{"name":"School of Nursing, The Hong Kong Polytechnic University , Hong Kong SAR , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pui Ni","family":"Tam","sequence":"additional","affiliation":[{"name":"School of Nursing, The Hong Kong Polytechnic University , Hong Kong SAR , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nga Man","family":"Tsim","sequence":"additional","affiliation":[{"name":"School of Nursing, The Hong Kong Polytechnic University , Hong Kong SAR , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1660-0548","authenticated-orcid":false,"given":"Shamay Sheung Mei","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, The Hong Kong Polytechnic University , Hong Kong SAR , People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,1]]},"reference":[{"key":"2024041612381836600_CIT0001","first-page":"934","article-title":"Longitudinal trajectories of arterial stiffness and the role of blood pressure: The Baltimore Longitudinal Study of Aging","volume-title":"Hypertension","author":"AlGhatrif","year":"2013"},{"key":"2024041612381836600_CIT0002","first-page":"e110034","article-title":"Effects of exercise modalities on arterial stiffness and wave reflection: A systematic review and meta-analysis of randomized controlled trials","volume-title":"PLoS 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