{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:16:35Z","timestamp":1785161795445,"version":"3.55.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T00:00:00Z","timestamp":1558396800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AG033581"],"award-info":[{"award-number":["R01AG033581"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AG051628"],"award-info":[{"award-number":["R01AG051628"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AG056102"],"award-info":[{"award-number":["R01AG056102"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Michigan Alzheimer\u2019s Disease Core Center","award":["P30AG053760"],"award-info":[{"award-number":["P30AG053760"]}]},{"name":"Oregon Alzheimer\u2019s Disease Center","award":["P30AG008017"],"award-info":[{"award-number":["P30AG008017"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background and Objectives<\/jats:title>\n                  <jats:p>Social isolation is associated with a higher risk of dementia. We previously conducted and showed the efficacy of an intervention which uses conversation (the core component of social interactions) as a tool to enhance cognitive function. We now explore whether cognitive improvements through conversation-based intervention depend on an individual\u2019s personality.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Research Design and Methods<\/jats:title>\n                  <jats:p>We reexamined data from a 6-week randomized controlled trial (ClinicalTrials.gov Number: NCT01571427) to determine whether conversation-based intervention effects were moderated by personality traits in 83 older adults (mean age = 80.51 years, 49 cognitively intact, 34 individuals with mild cognitive impairment). The intervention group participated in daily 30-min face-to-face semi-structured conversations with trained interviewers through a web-enabled system for 6 weeks. At baseline, psychosocial questionnaires and a neuropsychological battery were completed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Intervention group participants with high agreeableness, conscientiousness, and extraversion exhibited significant improvements in language-based executive function tasks beyond changes in the control group (ps &amp;lt; .05). An opposite pattern for delayed recall memory and working memory tasks emerged among highly extraverted participants (ps &amp;lt; .05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion and Implications<\/jats:title>\n                  <jats:p>Our exploratory findings suggest the adaptive role of personality traits in conversation-based cognitive interventions may be limited to tasks incorporating a language component, and offer initial evidence for personalized approaches to cognitive health in late life.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/geront\/gnz063","type":"journal-article","created":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T19:21:20Z","timestamp":1555356080000},"page":"958-967","source":"Crossref","is-referenced-by-count":21,"title":["Personality Moderates Intervention Effects on Cognitive Function: A 6-Week Conversation-Based Intervention"],"prefix":"10.1093","volume":"60","author":[{"given":"Eric S","family":"Cerino","sequence":"first","affiliation":[{"name":"School of Social and Behavioral Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Hooker","sequence":"first","affiliation":[{"name":"School of Social and Behavioral Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Goodrich","sequence":"first","affiliation":[{"name":"Department of Neurology, Layton Aging and Alzheimer\u2019s Disease Center, Oregon Health and Science University, Portland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko H","family":"Dodge","sequence":"first","affiliation":[{"name":"Department of Neurology, Layton Aging and Alzheimer\u2019s Disease Center, Oregon Health and Science University, Portland"},{"name":"Department of Neurology, Michigan Alzheimer\u2019s Disease Center, University of Michigan, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,5,21]]},"reference":[{"key":"2020071508023615900_CIT0001","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S1474-4422(06)70417-3","article-title":"The effect of social networks on the relation between Alzheimer\u2019s disease pathology and level of cognitive function in old people: A longitudinal cohort study","volume":"5","author":"Bennett","year":"2006","journal-title":"The Lancet. 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