{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T03:34:03Z","timestamp":1782444843570,"version":"3.54.5"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2018,11,10]],"date-time":"2018-11-10T00:00:00Z","timestamp":1541808000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["Horizon2020"],"award-info":[{"award-number":["Horizon2020"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["660328"],"award-info":[{"award-number":["660328"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["122035"],"award-info":[{"award-number":["122035"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"Netherlands Organisation for Scientific Research","doi-asserted-by":"publisher","award":["824.14.022"],"award-info":[{"award-number":["824.14.022"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Active sensing is crucial for navigation. It is characterized by self-generated motor action controlling the accessibility and processing of sensory information. In rodents, active sensing is commonly studied in the whisker system. As rats and mice modulate their whisking contextually, they employ frequency and amplitude modulation. Understanding the development, mechanisms, and plasticity of adaptive motor control will require precise behavioral measurements of whisker position.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Findings<\/jats:title>\n                  <jats:p>Advances in high-speed videography and analytical methods now permit collection and systematic analysis of large datasets. Here, we provide 6,642 videos as freely moving juvenile (third to fourth postnatal week) and adult rodents explore a stationary object on the gap-crossing task. The dataset includes sensory exploration with single- or multi-whiskers in wild-type animals, serotonin transporter knockout rats, rats received pharmacological intervention targeting serotonergic signaling. The dataset includes varying background illumination conditions and signal-to-noise ratios (SNRs), ranging from homogenous\/high contrast to non-homogenous\/low contrast. A subset of videos has been whisker and nose tracked and are provided as reference for image processing algorithms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The recorded behavioral data can be directly used to study development of sensorimotor computation, top-down mechanisms that control sensory navigation and whisker position, and cross-species comparison of active sensing. It could also help to address contextual modulation of active sensing during touch-induced whisking in head-fixed vs freely behaving animals. Finally, it provides the necessary data for machine learning approaches for automated analysis of sensory and motion parameters across a wide variety of signal-to-noise ratios with accompanying human observer-determined ground-truth.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gigascience\/giy134","type":"journal-article","created":{"date-parts":[[2018,11,10]],"date-time":"2018-11-10T10:25:26Z","timestamp":1541845526000},"source":"Crossref","is-referenced-by-count":18,"title":["An open-source high-speed infrared videography database to study the principles of active sensing in freely navigating rodents"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2260-5399","authenticated-orcid":false,"given":"Alireza","family":"Azarfar","sequence":"first","affiliation":[{"name":"Department of Neurophysiology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 HJ The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4142-2483","authenticated-orcid":false,"given":"Yiping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurophysiology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 HJ The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1009-2549","authenticated-orcid":false,"given":"Artoghrul","family":"Alishbayli","sequence":"additional","affiliation":[{"name":"Department of Neurophysiology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 HJ The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8513-0549","authenticated-orcid":false,"given":"St\u00e9phanie","family":"Miceli","sequence":"additional","affiliation":[{"name":"Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical School, Kapittelweg 29, Nijmegen, 6525 EN The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8451-4708","authenticated-orcid":false,"given":"Lara","family":"Kepser","sequence":"additional","affiliation":[{"name":"Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical School, Kapittelweg 29, Nijmegen, 6525 EN The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7282-6034","authenticated-orcid":false,"given":"Daan","family":"van der Wielen","sequence":"additional","affiliation":[{"name":"Department of Neurophysiology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 HJ The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7390-9608","authenticated-orcid":false,"given":"Mike","family":"van de Moosdijk","sequence":"additional","affiliation":[{"name":"Department of Neurophysiology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 HJ The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7621-1010","authenticated-orcid":false,"given":"Judith","family":"Homberg","sequence":"additional","affiliation":[{"name":"Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical School, Kapittelweg 29, Nijmegen, 6525 EN The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1202-4363","authenticated-orcid":false,"given":"Dirk","family":"Schubert","sequence":"additional","affiliation":[{"name":"Department of Neurophysiology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 HJ The Netherlands"},{"name":"Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical School, Kapittelweg 29, Nijmegen, 6525 EN The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5829-1344","authenticated-orcid":false,"given":"R\u00e9mi","family":"Proville","sequence":"additional","affiliation":[{"name":"Department of Neurophysiology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 HJ The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9629-0334","authenticated-orcid":false,"given":"Tansu","family":"Celikel","sequence":"additional","affiliation":[{"name":"Department of Neurophysiology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 HJ The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,11,10]]},"reference":[{"key":"2024111706461314600_bib1","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1073\/pnas.0610267104","article-title":"Sensory integration across space and in time for decision making in the somatosensory system of rodents","volume":"104","author":"Celikel","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2024111706461314600_bib2","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1152\/jn.00465.2015","article-title":"Selection of head and whisker coordination strategies during goal-oriented active touch","volume":"115","author":"Schroeder","year":"2016","journal-title":"J Neurophysiol"},{"key":"2024111706461314600_bib3","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1002\/ar.23102","article-title":"The musculature that drives active touch by vibrissae and nose in mice","volume":"298","author":"Haidarliu","year":"2015","journal-title":"Anat Rec (Hoboken)"},{"issue":"Pt 18","key":"2024111706461314600_bib4","doi-asserted-by":"crossref","first-page":"3365","DOI":"10.1242\/jeb.105338","article-title":"The search space of the rat during whisking behavior","volume":"217","author":"Huet","year":"2014","journal-title":"J Exp Biol"},{"key":"2024111706461314600_bib5","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1016\/j.cub.2014.05.036","article-title":"Strategy change in vibrissal active sensing during rat locomotion","volume":"24","author":"Arkley","year":"2014","journal-title":"Curr Biol"},{"key":"2024111706461314600_bib6","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1152\/jn.00241.2014","article-title":"Tactile object localization by anticipatory whisker motion","volume":"113","author":"Voigts","year":"2015","journal-title":"J Neurophysiol"},{"key":"2024111706461314600_bib7","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1126\/science.1143808","article-title":"Ongoing in vivo experience triggers synaptic metaplasticity in the neocortex","volume":"319","author":"Clem","year":"2008","journal-title":"Science"},{"key":"2024111706461314600_bib8","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1152\/jn.00012.2008","article-title":"Unsupervised whisker tracking in unrestrained behaving animals","volume":"100","author":"Voigts","year":"2008","journal-title":"J Neurophysiol"},{"key":"2024111706461314600_bib9","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1002\/hipo.22184","article-title":"Circuit mechanisms of GluA1-dependent spatial working memory","volume":"23","author":"Freudenberg","year":"2013","journal-title":"Hippocampus"},{"key":"2024111706461314600_bib10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3389\/neuro.01.1.1.007.2007","article-title":"Select overexpression of homer1a in dorsal hippocampus impairs spatial working memory","volume":"1","author":"Celikel","year":"2007","journal-title":"Front Neurosci"},{"key":"2024111706461314600_bib11","first-page":"1035","article-title":"Feedback control in active sensing: rat exploratory whisking is modulated by environmental contact","volume":"274","author":"Mitchinson","year":"2007","journal-title":"Proc Biol Sci"},{"key":"2024111706461314600_bib12","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3389\/fnbeh.2012.00039","article-title":"The role of orienting in vibrissal touch sensing","volume":"6","author":"Grant","year":"2012","journal-title":"Front Behav Neurosci"},{"key":"2024111706461314600_bib13","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.nbd.2016.09.007","article-title":"Somatosensory map expansion and altered processing of tactile inputs in a mouse model of fragile X syndrome","volume":"96","author":"Juczewski","year":"2016","journal-title":"Neurobiol Dis"},{"key":"2024111706461314600_bib14","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0896-6273(03)00391-X","article-title":"Serotonin regulates rhythmic whisking","volume":"39","author":"Hattox","year":"2003","journal-title":"Neuron"},{"key":"2024111706461314600_bib15","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1093\/cercor\/bhx016","article-title":"Reduced inhibition within layer IV of sert knockout rat barrel cortex is associated with faster sensory integration","volume":"27","author":"Miceli","year":"2017","journal-title":"Cereb Cortex"},{"key":"2024111706461314600_bib16","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/978-1-4939-2975-7_11","article-title":"Impact of monoaminergic neuromodulators on the development of sensorimotor circuits","volume-title":"Sensorimotor Integration in the Whisker System","author":"Schubert","year":"2015"},{"key":"2024111706461314600_bib17","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1016\/j.neuroscience.2007.03.030","article-title":"Characterization of the serotonin transporter knockout rat: a selective change in the functioning of the serotonergic system","volume":"146","author":"Homberg","year":"2007","journal-title":"Neuroscience"},{"key":"2024111706461314600_bib18","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1111\/j.1460-9568.2012.08075.x","article-title":"Development and critical period plasticity of the barrel cortex","volume":"35","author":"Erzurumlu","year":"2012","journal-title":"Eur J Neurosci"},{"key":"2024111706461314600_bib19","author":"Controller DNP Bitbucket","year":": 30  2018"},{"key":"2024111706461314600_bib20","author":"DeepLabCut GitHub"},{"key":"2024111706461314600_bib21","author":"Matlab Whister Tracker GitHub","year":": 30  2018"},{"key":"2024111706461314600_bib22","doi-asserted-by":"crossref","first-page":"e23869","DOI":"10.1371\/journal.pone.0023869","article-title":"Mapping functional brain activation using [14C]-iodoantipyrine in male serotonin transporter knockout mice","volume":"6","author":"Pang","year":"2011","journal-title":"PLoS One"},{"key":"2024111706461314600_bib23","doi-asserted-by":"crossref","unstructured":"Azarfar A, Zhang Y, Alishbayli A, Supporting data for \u201cAn open-source high-speed infrared videography database to study the principles of active sensing in freely navigating rodents.\u201d. GigaScience Database. 2018. 10.5524\/100512.","DOI":"10.1093\/gigascience\/giy134"}],"container-title":["GigaScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/gigascience\/article-pdf\/7\/12\/giy134\/60709268\/gigascience_7_12_giy134.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/gigascience\/article-pdf\/7\/12\/giy134\/60709268\/gigascience_7_12_giy134.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,17]],"date-time":"2024-11-17T06:46:46Z","timestamp":1731826006000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/gigascience\/article\/doi\/10.1093\/gigascience\/giy134\/5168870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,10]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/gigascience\/giy134","relation":{},"ISSN":["2047-217X"],"issn-type":[{"value":"2047-217X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,12]]},"published":{"date-parts":[[2018,11,10]]},"article-number":"giy134"}}