{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:24:43Z","timestamp":1792794283675,"version":"4.5.0"},"reference-count":112,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Scientific Research Deanship at University of Ha\u2019il","id":[{"id":"https:\/\/ror.org\/013w98a82","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Hyperglycemia is a poorly controlled diabetic condition, affects about 70% of people all round the world. In the year 2015, about 41.5 crore people were diabetic and is expected to reach around 64.3 crore by the year 2040. Cardiovascular diseases (CVDs) are considered as one of the major risk factors that cause more than half of the death of diabetic patients and promote related comorbidities. Atherosclerosis and amyloidosis are the prime factors linked with CVDs. Apolipoprotein A-I (ApoA-I) of HDL have protective action against CVDs, participate in reverse cholesterol transport mechanism and lipid metabolism, but gets easily glycated under prolonged hyperglycemic aura, i.e. glycation. ApoA-I have a potent role in maintenance of glucose level, providing a compelling link between diabetes and CVDs. Increased protein glycation in people with diabetes promote atherosclerosis, which might play possible role in promotion of protein aggregation by altering the protein structure and its confirmation. Here, we intend to investigate the mechanistic behavior of ApoA-I under the menace of glycation and its impact on ApoA-I structure and function that possibly link with aggregation or amyloidosis.<\/jats:p>","DOI":"10.1093\/glycob\/cwad010","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T10:15:10Z","timestamp":1675851310000},"source":"Crossref","is-referenced-by-count":5,"title":["Differential impact of glycation on apolipoprotein A-I of high-density lipoprotein: a review"],"prefix":"10.1093","author":[{"given":"Farah","family":"Maarfi","sequence":"first","affiliation":[{"name":"Uttaranchal University Department of Biotechnology, School of Applied & Life Sciences (SALS), , Dehradun 248007, Uttarakhand , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1215-0279","authenticated-orcid":false,"given":"Saheem","family":"Ahmad","sequence":"additional","affiliation":[{"name":"University of Hail Department of Medical Laboratory Sciences, College of Applied Medical Sciences, , Hail 2440 , Saudi Arabia"},{"name":"University of Hail Molecular Diagnostic & Personalized Therapeutic Unit, , Hail 2440 , Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3443-9700","authenticated-orcid":false,"given":"Sultan","family":"Alouffi","sequence":"additional","affiliation":[{"name":"University of Hail Department of Medical Laboratory Sciences, College of Applied Medical Sciences, , Hail 2440 , Saudi Arabia"},{"name":"University of Hail Molecular Diagnostic & Personalized Therapeutic Unit, , Hail 2440 , Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rihab","family":"Akasha","sequence":"additional","affiliation":[{"name":"University of Hail Department of Medical Laboratory Sciences, College of Applied Medical Sciences, , Hail 2440 , Saudi Arabia"},{"name":"University of Hail Molecular Diagnostic & Personalized Therapeutic Unit, , Hail 2440 , Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M Salman","family":"Khan","sequence":"additional","affiliation":[{"name":"Integral University Department of Biosciences, IIRC-5, Clinical Biochemistry and Natural Product Research Lab, , Lucknow 226026, Uttar Pradesh , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeeshan","family":"Rafi","sequence":"additional","affiliation":[{"name":"Integral University Department of Bioengineering, , Lucknow 226026, Uttar Pradesh , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemashri","family":"Basnet","sequence":"additional","affiliation":[{"name":"Uttaranchal University Department of Biotechnology, School of Applied & Life Sciences (SALS), , Dehradun 248007, Uttarakhand , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1107-7428","authenticated-orcid":false,"given":"Mohd Yasir","family":"Khan","sequence":"additional","affiliation":[{"name":"Uttaranchal University Department of Biotechnology, School of Applied & Life Sciences (SALS), , Dehradun 248007, Uttarakhand , India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,2,10]]},"reference":[{"key":"2023060913405531900_ref1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.semcancer.2017.10.005","article-title":"Oxidation glycation and glycoxidation\u2014the vicious cycle and lung cancer","volume":"49","author":"Ahmad","year":"2018","journal-title":"Semin Cancer Biol"},{"key":"2023060913405531900_ref2","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/5583298","article-title":"Physicochemical characterization of in vitro LDL glycation and its inhibition by ellagic acid (EA): an in vivo approach to inhibit diabetes in experimental animals","volume":"2022","author":"Ahmad","year":"2022","journal-title":"Biomed Res Int"},{"key":"2023060913405531900_ref3","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.ijbiomac.2022.05.198","article-title":"Carvacrol protects against carbonyl osmolyte-induced structural modifications and aggregation to serum albumin: insights from physicochemical and molecular interaction studies","volume":"213","author":"Ahmad","year":"2022","journal-title":"Int J Biol Macromol"},{"issue":"5","key":"2023060913405531900_ref4","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1002\/cbf.3722","article-title":"Nonenzymatic glycosylation of isolated human immunoglobulin-G by D-ribose","volume":"40","author":"Ahmad","year":"2022","journal-title":"Cell Biochem Funct"},{"issue":"7","key":"2023060913405531900_ref5","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1073\/pnas.0506877103","article-title":"Crystal structure of human apolipoprotein AI: insights into its protective effect against cardiovascular diseases","volume":"103","author":"Ajees","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"issue":"11","key":"2023060913405531900_ref6","doi-asserted-by":"crossref","first-page":"773","DOI":"10.2174\/1389203723666220929105859","article-title":"Glycation of immunoglobulin-G from pentose sugar: a cause for structural perturbations","volume":"23","author":"Alenazi","year":"2022","journal-title":"Curr Protein Pept Sci"},{"issue":"7","key":"2023060913405531900_ref7","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/cbf.3744","article-title":"Antiglycation potential of plant based TiO2 nanoparticle in D-ribose glycated BSA in vitro","volume":"40","author":"Alenazi","year":"2022","journal-title":"Cell Biochem Funct"},{"issue":"4","key":"2023060913405531900_ref8","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1074\/jbc.M204801200","article-title":"Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein AI","volume":"278","author":"Andreola","year":"2003","journal-title":"J Biol Chem"},{"issue":"3","key":"2023060913405531900_ref9","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.jacl.2015.02.005","article-title":"Case report: a novel apolipoprotein AI missense mutation apoA-I (Arg149Ser) Boston associated with decreased lecithin-cholesterol acyltransferase activation and cellular cholesterol efflux","volume":"9","author":"Anthanont","year":"2015","journal-title":"J Clin Lipidol"},{"issue":"4","key":"2023060913405531900_ref10","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1111\/j.1365-2621.1984.tb10432.x","article-title":"Maillard browning of common amino acids and sugars","volume":"49","author":"Ashoor","year":"1984","journal-title":"J Food Sci"},{"issue":"2","key":"2023060913405531900_ref11","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1021\/bi00569a021","article-title":"Asymmetry of apolipoprotein AI in solution as assessed from ultracentrifugal, viscometric, and fluorescence polarization studies","volume":"18","author":"Barbeau","year":"1979","journal-title":"Biochemistry"},{"issue":"3","key":"2023060913405531900_ref12","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1194\/jlr.R012658","article-title":"Sequence conservation of apolipoprotein AI affords novel insights into HDL structure-function","volume":"52","author":"Bashtovyy","year":"2011","journal-title":"J Lipid Res"},{"key":"2023060913405531900_ref13","doi-asserted-by":"crossref","first-page":"113634","DOI":"10.1016\/j.biopha.2022.113634","article-title":"Leveraging knowledge of HDLs major protein ApoA1: structure, function, mutations, and potential therapeutics","volume":"154","author":"Bhale","year":"2022","journal-title":"Biomed Pharmacother"},{"key":"2023060913405531900_ref14","doi-asserted-by":"crossref","first-page":"12291","DOI":"10.1073\/pnas.94.23.12291","article-title":"Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation","volume":"94","author":"Borhani","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1\u20132","key":"2023060913405531900_ref15","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/S1388-1981(01)00081-6","article-title":"Structural models of human apolipoprotein AI: a critical analysis and review","volume":"1531","author":"Brouillette","year":"2001","journal-title":"Biochim Biophys Acta Mol Cell Biol Lipids"},{"issue":"2","key":"2023060913405531900_ref16","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s00125-004-1648-4","article-title":"Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells","volume":"48","author":"Brown","year":"2005","journal-title":"Diabetologia"},{"issue":"5","key":"2023060913405531900_ref17","doi-asserted-by":"crossref","first-page":"e65430","DOI":"10.1371\/journal.pone.0065430","article-title":"Apolipoprotein AI glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages","volume":"8","author":"Brown","year":"2013","journal-title":"PLoS One"},{"issue":"3","key":"2023060913405531900_ref18","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0006-291X(88)81336-6","article-title":"Non enzymatic glycation of apolipoprotein AI. Effects on its self-association and lipid binding properties","volume":"153","author":"Calvo","year":"1988","journal-title":"Biochem Biophys Res Commun"},{"issue":"24","key":"2023060913405531900_ref19","doi-asserted-by":"crossref","first-page":"18847","DOI":"10.1074\/jbc.M109.098434","article-title":"Exchange of apolipoprotein AI between lipid-associated and lipid-free states: a potential target for oxidative generation of dysfunctional high density lipoproteins","volume":"285","author":"Cavigiolio","year":"2010","journal-title":"J Biol Chem"},{"issue":"45","key":"2023060913405531900_ref20","doi-asserted-by":"crossref","first-page":"19005","DOI":"10.1073\/pnas.0909708106","article-title":"Helical structure and stability in human apolipoprotein AI by hydrogen exchange and mass spectrometry","volume":"106","author":"Chetty","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"2023060913405531900_ref21","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.numecd.2013.04.004","article-title":"AGEs, rather than hyperglycemia, are responsible for microvascular complications in diabetes: a \u201cglycoxidation-centric\u201d point of view","volume":"23","author":"Chilelli","year":"2013","journal-title":"Nutr Metab Cardiovasc"},{"issue":"10","key":"2023060913405531900_ref22","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1161\/ATVBAHA.114.304131","article-title":"Apolipoprotein AI increases insulin secretion and production from pancreatic \u03b2-cells via a G-protein-cAMP-PKA-FoxO1\u2013dependent mechanism","volume":"34","author":"Cochran","year":"2014","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"4","key":"2023060913405531900_ref24","doi-asserted-by":"crossref","first-page":"850","DOI":"10.3390\/cells10040850","article-title":"High density lipoproteins and diabetes","volume":"10","author":"Cochran","year":"2021","journal-title":"Cell"},{"issue":"3","key":"2023060913405531900_ref25","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s11883-021-00906-7","article-title":"APOA1: a protein with multiple therapeutic functions","volume":"23","author":"Cochran","year":"2021","journal-title":"Curr Atheroscler Rep"},{"issue":"5","key":"2023060913405531900_ref26","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1194\/jlr.M032904","article-title":"Discoidal HDL and apoA-I-derived peptides improve glucose uptake in skeletal muscle","volume":"54","author":"Dalla-Riva","year":"2013","journal-title":"J Lipid Res"},{"issue":"11","key":"2023060913405531900_ref27","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1111\/febs.12809","article-title":"Amyloidogenic mutations in human apolipoprotein A-I are not necessarily destabilizing\u2013a common mechanism of apolipoprotein A-I misfolding in familial amyloidosis and atherosclerosis","volume":"281","author":"Das","year":"2014","journal-title":"FEBS J"},{"issue":"12","key":"2023060913405531900_ref28","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.1016\/j.bbadis.2017.09.001","article-title":"Structural determinants in ApoA-I amyloidogenic variants explain improved cholesterol metabolism despite low HDL levels","volume":"1863","author":"Del Giudice","year":"2017","journal-title":"BiochimBiophys Acta - Mol Basis Dis"},{"issue":"9","key":"2023060913405531900_ref29","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1016\/j.bbadis.2018.05.014","article-title":"Site-specific glycations of apolipoprotein AI lead to differentiated functional effects on lipid-binding and on glucose metabolism","volume":"1864","author":"Domingo-Esp\u00edn","year":"2018","journal-title":"Biochim Biophys Acta - Mol Basis Dis"},{"issue":"15","key":"2023060913405531900_ref30","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1161\/CIRCULATIONAHA.108.843219","article-title":"High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus","volume":"119","author":"Drew","year":"2009","journal-title":"Circulation"},{"issue":"4","key":"2023060913405531900_ref31","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/nrendo.2011.235","article-title":"The emerging role of HDL in glucose metabolism","volume":"8","author":"Drew","year":"2012","journal-title":"Nat Rev Endocrinol"},{"issue":"1","key":"2023060913405531900_ref32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12933-018-0728-6","article-title":"Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007\u20132017","volume":"17","author":"Einarson","year":"2018","journal-title":"Cardiovasc Diabetol"},{"issue":"3","key":"2023060913405531900_ref33","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1586\/erc.11.182","article-title":"HDL dysfunction in diabetes: causes and possible treatments","volume":"10","author":"Farbstein","year":"2012","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"2023060913405531900_ref34","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/978-3-319-09665-0_4","article-title":"Cholesterol efflux and reverse cholesterol transport","volume":"224","author":"Favari","year":"2015","journal-title":"High Density Lipoproteins"},{"issue":"1","key":"2023060913405531900_ref35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12944-017-0446-1","article-title":"Low apoA-I is associated with insulin resistance in patients with impaired glucose tolerance: a cross-sectional study","volume":"16","author":"Feng","year":"2017","journal-title":"Lipids Health Dis"},{"issue":"12","key":"2023060913405531900_ref36","first-page":"785","article-title":"LCAT, ApoD, and ApoA-I expression and review of cholesterol deposition in the cornea","volume":"9","author":"Flores","year":"2019","journal-title":"Biomol Ther"},{"issue":"5","key":"2023060913405531900_ref37","doi-asserted-by":"crossref","first-page":"880","DOI":"10.14336\/AD.2017.1121","article-title":"Glycation damage: a possible hub for major pathophysiological disorders and aging 2018","volume":"9","author":"Fournet","year":"2018","journal-title":"Aging Dis"},{"issue":"6","key":"2023060913405531900_ref38","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S0022-2275(20)32028-9","article-title":"Apolipoprotein AI: structure\u2013function relationships","volume":"41","author":"Frank","year":"2000","journal-title":"J Lipid Res"},{"issue":"3","key":"2023060913405531900_ref39","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.bbagen.2017.11.018","article-title":"Cell milieu significantly affects the fate of ApoAI amyloidogenic variants: predestination or serendipity?","volume":"1862","author":"Gaglione","year":"2018","journal-title":"BiochimBiophys Acta - Gen Subj"},{"issue":"8","key":"2023060913405531900_ref40","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.2337\/dc09-0256","article-title":"Poor glycemic control is an independent risk factor for low HDL cholesterol in patients with type 2 diabetes","volume":"32","author":"Gatti","year":"2009","journal-title":"Diabetes Care"},{"issue":"9","key":"2023060913405531900_ref41","doi-asserted-by":"crossref","first-page":"e134","DOI":"10.1038\/nutd.2014.31","article-title":"Arginine-directed glycation and decreased HDL plasma concentration and functionality","volume":"4","author":"Godfrey","year":"2014","journal-title":"Nutr Diabetes"},{"issue":"7","key":"2023060913405531900_ref42","doi-asserted-by":"crossref","first-page":"2991","DOI":"10.1073\/pnas.93.7.2991","article-title":"Thermal unfolding of human high-density apolipoprotein A-1: implications for a lipid-free molten globular state","volume":"93","author":"Gursky","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"2023060913405531900_ref43","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1021\/bi2017014","article-title":"The crystal structure of the C-terminal truncated apolipoprotein AI sheds new light on amyloid formation by the N-terminal fragment","volume":"51","author":"Gursky","year":"2012","journal-title":"Biochemistry"},{"key":"2023060913405531900_ref44","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1007\/s00125-007-0752-7","article-title":"Apolipoprotein AI stimulates AMP-activated protein kinase and improves glucose metabolism","volume":"50","author":"Han","year":"2007","journal-title":"Diabetologia"},{"key":"2023060913405531900_ref45","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3389\/fmolb.2014.00009","article-title":"Differential effects of glycation on protein aggregation and amyloid formation","volume":"1","author":"Iannuzzi","year":"2014","journal-title":"Front Mol Biosci"},{"issue":"10","key":"2023060913405531900_ref46","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1016\/j.ekir.2021.07.014","article-title":"Fibrinogen a alpha-chain amyloidosis associated with a novel variant in a Chinese family","volume":"6","author":"Jin","year":"2021","journal-title":"Kidney Int Rep"},{"issue":"2","key":"2023060913405531900_ref47","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1210\/jc.2017-01551","article-title":"Glycation reduces the stability of ApoAI and increases HDL dysfunction in diet-controlled type 2 diabetes","volume":"103","author":"Kashyap","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"key":"2023060913405531900_ref48","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ijbiomac.2018.04.016","article-title":"Immunochemical studies on native and glycated LDL\u2013an approach to uncover the structural perturbations","volume":"115","author":"Khan","year":"2018","journal-title":"Int J Biol Macromol"},{"key":"2023060913405531900_ref49","doi-asserted-by":"crossref","first-page":"104062","DOI":"10.1016\/j.cellimm.2020.104062","article-title":"The neoepitopes on methylglyoxal (MG) glycated LDL create autoimmune response; autoimmunity detection in T2DM patients with varying disease duration","volume":"351","author":"Khan","year":"2020","journal-title":"Cell Immunol"},{"issue":"17","key":"2023060913405531900_ref50","doi-asserted-by":"crossref","first-page":"3572","DOI":"10.1046\/j.1432-1033.2002.03017.x","article-title":"Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes: formation of modified and oxidized particles","volume":"270","author":"Knott","year":"2003","journal-title":"Eur J Biochem"},{"issue":"6","key":"2023060913405531900_ref51","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/9504","article-title":"The intrinsic factor\u2013vitamin B12 receptor, cubilin, is a high-affinity Apo lipoprotein AI receptor facilitating endocytosis of high-density lipoprotein","volume":"5","author":"Kozyraki","year":"1999","journal-title":"Nat Med"},{"issue":"3","key":"2023060913405531900_ref52","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/jcla.21591","article-title":"Semiquantitative analysis of apolipoprotein A-I modified by advanced glycation end products in diabetes mellitus","volume":"27","author":"Kurosaki","year":"2013","journal-title":"J Clin Lab Anal"},{"issue":"3","key":"2023060913405531900_ref53","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1046\/j.1365-2796.2001.00789.x","article-title":"Cardiovascular disease in type 2 diabetes: challenge for treatment and prevention","volume":"249","author":"Laakso","year":"2001","journal-title":"J Intern Med"},{"issue":"1","key":"2023060913405531900_ref54","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/jms.1274","article-title":"On the search for glycated lipoprotein ApoA-I in the plasma of diabetic and nephropathic patients","volume":"43","author":"Lapolla","year":"2008","journal-title":"J Mass Spectrom"},{"issue":"22","key":"2023060913405531900_ref55","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1161\/CIRCULATIONAHA.113.001551","article-title":"High-density lipoprotein maintains skeletal muscle function by modulating cellular respiration in mice","volume":"128","author":"Lehti","year":"2013","journal-title":"Circulation"},{"key":"2023060913405531900_ref56","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.yjmcc.2018.08.001","article-title":"Lysine glycation of apolipoprotein AI impairs its anti-inflammatory function in type 2 diabetes mellitus","volume":"122","author":"Liu","year":"2018","journal-title":"J Mol Cell Cardiol"},{"key":"2023060913405531900_ref57","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/978-90-481-8622-8_7","article-title":"High density lipoprotein structure\u2013function and role in reverse cholesterol transport","volume":"51","author":"Lund-Katz","year":"2010","journal-title":"Cholesterol Binding Cholesterol Transport Proteins"},{"issue":"24","key":"2023060913405531900_ref58","doi-asserted-by":"crossref","first-page":"18119","DOI":"10.1016\/S0021-9258(17)46819-0","article-title":"Nonenzymatic glycation alters protein structure and stability. A study of two eye lens crystallins","volume":"268","author":"Luthra","year":"1993","journal-title":"J Biol Chem"},{"issue":"2","key":"2023060913405531900_ref59","first-page":"3539","article-title":"Structural insights into human apolipoprotein A1 variants and their correlation with amyloidogenic propensities: an in silico approach","volume":"19","author":"Maarfi","year":"2019","journal-title":"Biochem Cell Arch"},{"key":"2023060913405531900_ref60","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/978-981-16-4558-7_11","volume-title":"Autism spectrum disorder and Alzheimer's disease","author":"Maarfi","year":"2021"},{"key":"2023060913405531900_ref61","first-page":"1","article-title":"A study on multiple facets of apolipoprotein A1 Milano","author":"Maarfi","year":"2023","journal-title":"Appl Biochem Biotechnol"},{"key":"2023060913405531900_ref62","first-page":"100815","article-title":"Probing the structure\u2013function relationship and amyloidogenic propensities in natural variants of apolipoprotein AI","volume":"24","author":"Ma'arfi","year":"2020","journal-title":"Biochem Biophys Rep"},{"issue":"1","key":"2023060913405531900_ref63","doi-asserted-by":"crossref","first-page":"e013531","DOI":"10.1161\/JAHA.119.013531","article-title":"Role of high density lipoproteins in cholesterol homeostasis and glycemic control","volume":"9","author":"Manandhar","year":"2020","journal-title":"J Am Heart Assoc"},{"issue":"2","key":"2023060913405531900_ref64","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.atherosclerosis.2009.03.003","article-title":"Metformin restores impaired HDL-mediated cholesterol efflux due to glycation","volume":"206","author":"Matsuki","year":"2009","journal-title":"Atherosclerosis"},{"issue":"1","key":"2023060913405531900_ref65","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12967-021-02797-3","article-title":"Glucose excursions in type 2 diabetes modulate amyloid-related proteins associated with dementia","volume":"19","author":"Moin","year":"2021","journal-title":"J Transl Med"},{"key":"2023060913405531900_ref66","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1073\/pnas.81.2.583","article-title":"Accelerated age-related browning of human collagen in diabetes mellitus","volume":"81","author":"Monnier","year":"1984","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"2023060913405531900_ref67","first-page":"H76","article-title":"The effects of exercise training on lipid metabolism and coronary heart disease","volume":"319","author":"Muscella","year":"2020","journal-title":"Am J Phys Heart Circ Phys"},{"key":"2023060913405531900_ref68","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s00125-006-0574-z","article-title":"The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin:cholesterol acyltransferase","volume":"50","author":"Nobecourt","year":"2007","journal-title":"Diabetologia"},{"issue":"4","key":"2023060913405531900_ref69","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1161\/ATVBAHA.109.201715","article-title":"Nonenzymatic glycation impairs the anti-inflammatory properties of apolipoprotein AI","volume":"30","author":"Nob\u00e9court","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"3","key":"2023060913405531900_ref70","first-page":"45","article-title":"Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links","volume":"11","author":"Oguntibeju","year":"2019","journal-title":"Int J Physiol Pathophysiol Pharmacol"},{"issue":"4","key":"2023060913405531900_ref71","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1093\/clinchem\/39.4.625","article-title":"Specific glycation of albumin depends on its half-life","volume":"39","author":"Olgem\u00f6ller","year":"1993","journal-title":"Clin Chem"},{"issue":"6","key":"2023060913405531900_ref72","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1093\/gerona\/glq034","article-title":"Senescence-related truncation and multimerization of apolipoprotein AI in high-density lipoprotein with an elevated level of advanced glycated end products and cholesteryl ester transfer activity","volume":"65","author":"Park","year":"2010","journal-title":"J Gerontol A Biol Sci Med Sci J"},{"issue":"2","key":"2023060913405531900_ref73","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.gene.2003.11.024","article-title":"Helper-dependent adenoviral vector-mediated long-term expression of human apolipoprotein AI reduces atherosclerosis in apo E-deficient mice","volume":"327","author":"Pastore","year":"2004","journal-title":"Gene"},{"issue":"10","key":"2023060913405531900_ref74","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1002\/bip.22865","article-title":"Molecular crowding impacts the structure of apolipoprotein A-I with potential implications on in vivo metabolism and function","volume":"105","author":"Petrlova","year":"2016","journal-title":"Biopolymers"},{"issue":"35","key":"2023060913405531900_ref75","doi-asserted-by":"crossref","first-page":"4971","DOI":"10.1021\/acs.biochem.6b00347","article-title":"High-density lipoprotein biogenesis: defining the domains involved in human apolipoprotein AI lipidation","volume":"55","author":"Pollard","year":"2016","journal-title":"Biochemistry"},{"issue":"5","key":"2023060913405531900_ref76","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.2337\/dc12-1411","article-title":"Glycation of apoprotein AI is associated with coronary artery plaque progression in type 2 diabetic patients","volume":"36","author":"Pu","year":"2013","journal-title":"Diabetes Care"},{"key":"2023060913405531900_ref77","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.2337\/db11-0085","article-title":"Conversion of low density lipoprotein to the pro-atherogenic form by methylglyoxal with increased arterial proteoglycan binding and aortal retention","volume":"60","author":"Rabbani","year":"2011","journal-title":"Diabetes"},{"issue":"1","key":"2023060913405531900_ref78","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2337\/db14-1516","article-title":"Hidden complexities in the measurement of fructosyl-lysine and advanced glycation end products for risk prediction of vascular complications of diabetes","volume":"64","author":"Rabbani","year":"2015","journal-title":"Diabetes"},{"key":"2023060913405531900_ref79","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s11883-010-0091-x","article-title":"Dysfunctional high-density lipoprotein and atherosclerosis","volume":"12","author":"Ragbir","year":"2010","journal-title":"Curr Atheroscler Rep"},{"issue":"4","key":"2023060913405531900_ref80","doi-asserted-by":"crossref","first-page":"e011295","DOI":"10.1161\/JAHA.118.011295","article-title":"Diabetes mellitus\u2013related all-cause and cardiovascular mortality in a national cohort of adults","volume":"8","author":"Raghavan","year":"2019","journal-title":"J Am Heart Assoc"},{"issue":"7","key":"2023060913405531900_ref81","doi-asserted-by":"crossref","first-page":"e22532","DOI":"10.1371\/journal.pone.0022532","article-title":"Human apolipoprotein AI-derived amyloid: its association with atherosclerosis","volume":"6","author":"Ramella","year":"2011","journal-title":"PLoS One"},{"issue":"19","key":"2023060913405531900_ref82","doi-asserted-by":"crossref","first-page":"6013","DOI":"10.1016\/S0021-9258(17)33052-1","article-title":"Conformational stability of the polypeptide components of human high density serum lipoprotein","volume":"251","author":"Reynolds","year":"1976","journal-title":"J Biol Chem"},{"issue":"1","key":"2023060913405531900_ref83","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0022-2275(20)32333-6","article-title":"Three arginine residues in apolipoprotein AI are critical for activation of lecithin:cholesterol acyltransferase","volume":"42","author":"Roosbeek","year":"2001","journal-title":"J Lipid Res"},{"issue":"4","key":"2023060913405531900_ref84","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1582-4934.2010.01045.x","article-title":"Apolipoprotein A-I possesses an anti-obesity effect associated with increase of energy expenditure and up-regulation of UCP1 in brown fat","volume":"15","author":"Ruan","year":"2011","journal-title":"J Cell Mol Med"},{"issue":"3","key":"2023060913405531900_ref85","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1161\/01.ATV.0000104029.74961.f5","article-title":"Formation and metabolism of prebeta-migrating, lipid-poor apolipoprotein AI","volume":"24","author":"Rye","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol."},{"issue":"26","key":"2023060913405531900_ref86","doi-asserted-by":"crossref","first-page":"23227","DOI":"10.1074\/jbc.M303365200","article-title":"Domain structure and lipid interaction in human apolipoproteins AI and E, a general model","volume":"278","author":"Saito","year":"2003","journal-title":"J Biol Chem"},{"issue":"3","key":"2023060913405531900_ref87","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1097\/00041433-200006000-00007","article-title":"Lecithin-cholesterol acyltransferase: role in lipoprotein metabolism, reverse cholesterol transport and atherosclerosis","volume":"11","author":"Santamarina-Fojo","year":"2000","journal-title":"Curr Opin Lipidol"},{"issue":"9733","key":"2023060913405531900_ref88","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1016\/S0140-6736(10)60484-9","article-title":"Emerging risk factors collaboration diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies","volume":"375","author":"Sarwar","year":"2010","journal-title":"Lancet"},{"issue":"24","key":"2023060913405531900_ref89","doi-asserted-by":"crossref","first-page":"18473","DOI":"10.1074\/jbc.M110.118182","article-title":"Modifying apolipoprotein AI by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway","volume":"285","author":"Shao","year":"2010","journal-title":"J Biol Chem"},{"issue":"1","key":"2023060913405531900_ref90","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12933-015-0221-4","article-title":"Association of elevated apoA-I glycation and reduced HDL-associated paraoxonase1, 3 activity, and their interaction with angiographic severity of coronary artery disease in patients with type 2 diabetes mellitus","volume":"14","author":"Shen","year":"2015","journal-title":"Cardiovasc Diabetol"},{"issue":"13","key":"2023060913405531900_ref91","doi-asserted-by":"crossref","first-page":"9713","DOI":"10.1074\/jbc.M610380200","article-title":"The structure of apolipoprotein A-II in discoidal high density lipoproteins","volume":"282","author":"Silva","year":"2007","journal-title":"J Biol Chem"},{"issue":"2","key":"2023060913405531900_ref92","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1161\/ATVBAHA.108.179226","article-title":"Dysfunctional HDL as a diagnostic and therapeutic target","volume":"30","author":"Smith","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"12","key":"2023060913405531900_ref93","doi-asserted-by":"crossref","first-page":"5710","DOI":"10.1073\/pnas.91.12.5710","article-title":"Advanced Maillard reaction end products are associated with Alzheimer disease pathology","volume":"91","author":"Smith","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"2023060913405531900_ref94","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1477-5956-12-5","article-title":"Plasma protein profiling of mild cognitive impairment and Alzheimer\u2019s disease using iTRAQ quantitative proteomics","volume":"12","author":"Song","year":"2014","journal-title":"Proteome Sci"},{"issue":"1","key":"2023060913405531900_ref95","first-page":"167","article-title":"Dysfunctional HDL in diabetes mellitus and its role in the pathogenesis of cardiovascular disease","volume":"440","author":"Srivastava","year":"2018","journal-title":"Mol Cell Biochem"},{"key":"2023060913405531900_ref96","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0065-3233(08)60320-4","article-title":"The structure of amyloid fibrils by electron microscopy and X-ray diffraction","volume":"50","author":"Sunde","year":"1997","journal-title":"Advances Protein Chem"},{"issue":"3","key":"2023060913405531900_ref97","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1006\/jmbi.1997.1348","article-title":"Common core structure of amyloid fibrils by synchrotron X-ray diffraction","volume":"273","author":"Sunde","year":"1997","journal-title":"J Mol Biol"},{"issue":"4","key":"2023060913405531900_ref98","doi-asserted-by":"crossref","first-page":"569","DOI":"10.3390\/molecules22040569","article-title":"Effect of temperature on tolbutamide binding to glycated serum albumin","volume":"22","author":"Szkudlarek","year":"2017","journal-title":"Molecules"},{"issue":"47","key":"2023060913405531900_ref99","doi-asserted-by":"crossref","first-page":"20021","DOI":"10.1073\/pnas.0905686106","article-title":"RAGE-mediated signaling contributes to intraneuronal transport of amyloid-\u03b2 and neuronal dysfunction","volume":"106","author":"Takuma","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"2023060913405531900_ref100","doi-asserted-by":"crossref","first-page":"3749","DOI":"10.1016\/S0021-9258(17)33407-5","article-title":"Conformational and thermodynamic properties of apo A-1 of human plasma high density lipoproteins","volume":"251","author":"Tall","year":"1976","journal-title":"J Biol Chem"},{"issue":"1","key":"2023060913405531900_ref101","first-page":"1","article-title":"Apolipoprotein AI enhances insulin-dependent and insulin-independent glucose uptake by skeletal muscle","volume":"9","author":"Tang","year":"2019","journal-title":"Sci Rep"},{"issue":"1","key":"2023060913405531900_ref102","first-page":"18","article-title":"Endothelial dysfunction in diabetes is aggravated by glycated lipoproteins; novel molecular therapies","volume":"9","author":"Toma","year":"2020","journal-title":"Biomedicine"},{"issue":"5440","key":"2023060913405531900_ref103","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1126\/science.286.5440.735","article-title":"\u03b2-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE","volume":"286","author":"Vassar","year":"1999","journal-title":"Science"},{"issue":"2","key":"2023060913405531900_ref104","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1399-3011.1996.tb00820.x","article-title":"Fourier-transform infrared conformational study of bovine insulin in surfactant solutions","volume":"48","author":"Vecchio","year":"1996","journal-title":"Int J Pept Protein Res"},{"key":"2023060913405531900_ref105","doi-asserted-by":"crossref","first-page":"9774","DOI":"10.1073\/pnas.0403506101","article-title":"ATP-binding cassette transporters G1 and G4 mediate cellular efflux to high-density lipoproteins","volume":"101","author":"Wang","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6","key":"2023060913405531900_ref106","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1161\/ATVBAHA.112.301195","article-title":"ABCA1 mediates unfolding of apolipoprotein AI N terminus on the cell surface before lipidation and release of nascent high-density lipoprotein","volume":"33","author":"Wang","year":"2013","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"1","key":"2023060913405531900_ref107","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/XCE.0000000000000120","article-title":"Dyslipidemia in diabetes mellitus and cardiovascular disease","volume":"6","author":"Warraich","year":"2017","journal-title":"Cardiovasc Endocrinol"},{"issue":"5","key":"2023060913405531900_ref108","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/ndt\/11.supp5.41","article-title":"New biomarkers of Maillard reaction damage to proteins","volume":"11","author":"Wells-Knecht","year":"1996","journal-title":"Nephrol Dial Transplant"},{"issue":"6","key":"2023060913405531900_ref109","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1001\/jamacardio.2016.1884","article-title":"Association of lipid fractions with risks for coronary artery disease and diabetes","volume":"1","author":"White","year":"2016","journal-title":"JAMA Cardiol"},{"issue":"5","key":"2023060913405531900_ref110","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1021\/jf60195a040","article-title":"Factors affecting the Maillard browning reaction between sugars and amino acids. Nonenzymic browning of dehydrated orange juice. J. Agric","volume":"22","author":"Wolfrom","year":"1974","journal-title":"Food Chem"},{"issue":"13","key":"2023060913405531900_ref111","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1016\/j.febslet.2012.05.007","article-title":"Identification of an amyloid fibril forming peptide comprising residues 46\u201359 of apolipoprotein AI","volume":"586","author":"Wong","year":"2012","journal-title":"FEBS Lett"},{"issue":"6593","key":"2023060913405531900_ref112","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/382685a0","article-title":"RAGE and amyloid-\u03b2 peptide neurotoxicity in Alzheimer's disease","volume":"382","author":"Yan","year":"1996","journal-title":"Nature"},{"issue":"4","key":"2023060913405531900_ref113","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/nchembio.796","article-title":"Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein","volume":"8","author":"Zhang","year":"2012","journal-title":"Nat Chem Biol"}],"container-title":["Glycobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/glycob\/advance-article-pdf\/doi\/10.1093\/glycob\/cwad010\/50519598\/cwad010.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/glycob\/advance-article-pdf\/doi\/10.1093\/glycob\/cwad010\/50519598\/cwad010.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T08:40:29Z","timestamp":1701852029000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/glycob\/advance-article\/doi\/10.1093\/glycob\/cwad010\/7034131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,10]]},"references-count":112,"URL":"https:\/\/doi.org\/10.1093\/glycob\/cwad010","relation":{},"ISSN":["1460-2423"],"issn-type":[{"value":"1460-2423","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,10]]},"article-number":"cwad010"}}