{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T17:01:19Z","timestamp":1784912479993,"version":"3.55.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"joint research program of the J-GlycoNet cooperative network","award":["25B003"],"award-info":[{"award-number":["25B003"]}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24\u00a0K08716"],"award-info":[{"award-number":["24\u00a0K08716"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23\u00a0K06190"],"award-info":[{"award-number":["23\u00a0K06190"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007802","name":"Institute for Fermentation, Osaka","doi-asserted-by":"publisher","award":["Y-2023-2-046"],"award-info":[{"award-number":["Y-2023-2-046"]}],"id":[{"id":"10.13039\/100007802","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pleurocybella porrigens is a mushroom that grows widely around the temperate northern hemisphere, and was once considered edible, especially in Japan. Following a number of deaths in 2004, investigations revealed the presence of various toxins, including a lectin (PPL) that apparently survives cooking and enters the bloodstream via the stomach. We have cloned PPL and solved its structure by X-ray crystallography and cryo-EM. We report the sugar binding properties of this \u03b2-trefoil lectin, which has a novel hexameric structure.<\/jats:p>","DOI":"10.1093\/glycob\/cwaf082","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T12:31:25Z","timestamp":1764592285000},"source":"Crossref","is-referenced-by-count":1,"title":["Crystal and Cryo-EM structure of PPL, a novel hexameric R-type lectin from the poisonous mushroom\n                    <i>Pleurocybella porrigens<\/i>"],"prefix":"10.1093","volume":"36","author":[{"given":"Daisuke","family":"Adachi","sequence":"first","affiliation":[{"name":"Graduate School of Medical Life Science, Yokohama City University , 1-7-29 Suehiro, Yokohama, Kanagawa 230-0045 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naito","family":"Ishimoto","sequence":"additional","affiliation":[{"name":"Graduate School of Medical Life Science, Yokohama City University , 1-7-29 Suehiro, Yokohama, Kanagawa 230-0045 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200G, 3001 Leuven ,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masao","family":"Yamada","sequence":"additional","affiliation":[{"name":"Graduate School of NanoBio Sciences, Yokohama City University , 22-2 Seto, Yokohama, Kanagawa 236-0027 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Ozeki","sequence":"additional","affiliation":[{"name":"Graduate School of NanoBio Sciences, Yokohama City University , 22-2 Seto, Yokohama, Kanagawa 236-0027 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Fujii","sequence":"additional","affiliation":[{"name":"Graduate School of Pharmaceutical Sciences, Nagasaki International University , 2825-7 Huis Ten Bosch, Sasebo, Nagasaki 859-3298 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Fujita","sequence":"additional","affiliation":[{"name":"Graduate 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