{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T15:32:02Z","timestamp":1788449522871,"version":"build-2803163510"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"vor","delay-in-days":30,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Mass drug administration (MDA) has reached up to 1 billion people annually to combat neglected tropical diseases (NTDs). This study explores the evolving NTD landscape in Africa amid shifting disease patterns, funding cuts, and universal health coverage goals.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We analyzed data from ESPEN and Sightsavers databases to assess historical trends and forecast future treatment needs.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>By 2027, few or no MDAs for lymphatic filariasis and trachoma will be required and MDAs for onchocerciasis dropped sharply after 2024. In contrast, schistosomiasis and soil-transmitted helminths continue to require widespread MDA.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>To secure elimination gains, remaining MDAs must be completed and broader health systems approaches adopted.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/haschl\/qxaf136","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T06:54:36Z","timestamp":1753944876000},"source":"Crossref","is-referenced-by-count":3,"title":["The changing neglected tropical disease landscape in Africa: implications for policy, practice, and strengthening health systems"],"prefix":"10.1093","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5960-973X","authenticated-orcid":false,"given":"Philip","family":"Downs","sequence":"first","affiliation":[{"name":"Sightsavers, Haywards Health, West Sussex RH16 3BW ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3495-6103","authenticated-orcid":false,"given":"Andrew","family":"Tate","sequence":"additional","affiliation":[{"name":"Sightsavers, Haywards Health, West Sussex RH16 3BW ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2504-3467","authenticated-orcid":false,"given":"Danny","family":"Harvey","sequence":"additional","affiliation":[{"name":"Sightsavers, Haywards Health, West Sussex RH16 3BW ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4537-3914","authenticated-orcid":false,"given":"Margaret C","family":"Baker","sequence":"additional","affiliation":[{"name":"Department of Global Health, Georgetown University , Washington, DC 20057 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"2025073102543314200_qxaf136-B1","author":"Edwine"},{"issue":"10493","key":"2025073102543314200_qxaf136-B2","doi-asserted-by":"publisher","first-page":"1893","DOI":"10.1016\/S0140-6736(25)00720-2","article-title":"Navigating health financing cliffs: a new era in global health","volume":"405","author":"Rasanathan","year":"2025","journal-title":"Lancet"},{"key":"2025073102543314200_qxaf136-B3","doi-asserted-by":"publisher","first-page":"107868","DOI":"10.1016\/j.ijid.2025.107868","article-title":"The changing funding landscape for infectious disease research and control: implications for resource-limited countries","volume":"154","author":"Bockarie","year":"2025","journal-title":"Int J Infect Dis"},{"key":"2025073102543314200_qxaf136-B4","author":"World Health Organization (WHO)"},{"issue":"10","key":"2025073102543314200_qxaf136-B5","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1056\/NEJMra064142","article-title":"Control of neglected tropical diseases","volume":"357","author":"Hotez","year":"2007","journal-title":"N Engl J Med."},{"issue":"1","key":"2025073102543314200_qxaf136-B6","doi-asserted-by":"publisher","first-page":"5","DOI":"10.4269\/ajtmh.2011.10-0411","article-title":"Integrated implementation of programs targeting neglected tropical diseases through preventive chemotherapy: proving the feasibility at national scale","volume":"84","author":"Linehan","year":"2011","journal-title":"Am J Trop Med Hyg"},{"key":"2025073102543314200_qxaf136-B7","author":"World Health Organization (WHO)"},{"issue":"12","key":"2025073102543314200_qxaf136-B8","doi-asserted-by":"publisher","first-page":"e0005037","DOI":"10.1371\/journal.pntd.0005037","article-title":"Benchmarking the cost per person of mass treatment for selected neglected tropical diseases: an approach based on literature review and meta-regression with web-based software application","volume":"10","author":"Fitzpatrick","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"issue":"6","key":"2025073102543314200_qxaf136-B9","doi-asserted-by":"publisher","first-page":"e708","DOI":"10.1371\/journal.pntd.0000708","article-title":"The economic benefits resulting from the first 8 years of the global programme to eliminate lymphatic filariasis (2000\u20132007)","volume":"4","author":"Chu","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"2025073102543314200_qxaf136-B10","author":"World Health Organization (WHO)"},{"issue":"5","key":"2025073102543314200_qxaf136-B11","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1093\/inthealth\/ihz012","article-title":"Gender equity in mass drug administration for neglected tropical diseases: data from 16 countries","volume":"11","author":"Cohn","year":"2019","journal-title":"Int Health."},{"key":"2025073102543314200_qxaf136-B12","author":"World Health Organization (WHO)"},{"key":"2025073102543314200_qxaf136-B13","author":"WHO ESPEN","year":"2025"},{"issue":"6","key":"2025073102543314200_qxaf136-B14","doi-asserted-by":"publisher","first-page":"e0008301","DOI":"10.1371\/journal.pntd.0008301","article-title":"Risk factors associated with failing pre-Transmission Assessment Surveys (pre-TAS) in lymphatic filariasis elimination programs: results of a multi-country analysis","volume":"14","author":"Burgert-Brucker","year":"2020","journal-title":"PLoS Negl Trop Dis"},{"key":"2025073102543314200_qxaf136-B15","author":"World Health Organization Expanded Special Project for Elimination of Neglected Tropical Diseases (WHO ESPEN)"},{"key":"2025073102543314200_qxaf136-B16","author":"World Health Organization (WHO)"},{"issue":"3","key":"2025073102543314200_qxaf136-B17","doi-asserted-by":"publisher","first-page":"735","DOI":"10.4269\/ajtmh.18-0169","article-title":"Comprehensive assessment of a hotspot with persistent bancroftian filariasis in coastal Sri Lanka","volume":"99","author":"Rao","year":"2018","journal-title":"Am J Trop Med Hyg."},{"issue":"2","key":"2025073102543314200_qxaf136-B18","doi-asserted-by":"publisher","first-page":"127","DOI":"10.4103\/0972-9062.321759","article-title":"Vector-borne diseases in Egypt: present status and accelerating toward elimination","volume":"59","author":"Eassa","year":"2022","journal-title":"J Vector Borne Dis."},{"issue":"12","key":"2025073102543314200_qxaf136-B19","doi-asserted-by":"publisher","first-page":"e0008877","DOI":"10.1371\/journal.pntd.0008877","article-title":"Achievements and challenges of lymphatic filariasis elimination in Sierra Leone","volume":"14","author":"Bah","year":"2020","journal-title":"PLoS Negl Trop Dis"},{"issue":"10","key":"2025073102543314200_qxaf136-B20","doi-asserted-by":"publisher","first-page":"e1346","DOI":"10.1371\/journal.pntd.0001346","article-title":"Epidemiological and entomological evaluations after six years or more of mass drug administration for lymphatic filariasis elimination in Nigeria","volume":"5","author":"Richards","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"2025073102543314200_qxaf136-B21","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1186\/s13071-014-0507-5","article-title":"Lymphatic filariasis control in Tanga region, Tanzania: status after eight rounds of mass drug administration","volume":"7","author":"Simonsen","year":"2014","journal-title":"Parasit Vectors."},{"key":"2025073102543314200_qxaf136-B22","doi-asserted-by":"crossref","first-page":"7408187","DOI":"10.1155\/2016\/7408187","article-title":"Current epidemiological assessment of bancroftian filariasis in Tanga region, northeastern Tanzania","volume":"2016","author":"Mshana","year":"2016","journal-title":"J Trop Med."},{"issue":"4","key":"2025073102543314200_qxaf136-B23","doi-asserted-by":"publisher","first-page":"e491","DOI":"10.1016\/S2214-109X(22)00050-X","article-title":"Global progress toward the elimination of active trachoma: an analysis of 38 countries","volume":"10","author":"Renneker","year":"2022","journal-title":"Lancet Glob Health."},{"key":"2025073102543314200_qxaf136-B24","author":"World Health Organization (WHO)"},{"issue":"10","key":"2025073102543314200_qxaf136-B25","doi-asserted-by":"publisher","first-page":"e0012521","DOI":"10.1371\/journal.pntd.0012521","article-title":"Need for a paradigm shift in soil-transmitted helminthiasis control: targeting the right people, in the right place, and with the right drug(s)","volume":"18","author":"Emerson","year":"2024","journal-title":"PLoS Negl Trop Dis"},{"key":"2025073102543314200_qxaf136-B26","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.actatropica.2016.08.004","article-title":"Increasing the reach: involving local Muslim religious teachers in a behavioral intervention to eliminate urogenital schistosomiasis in Zanzibar","volume":"163","author":"Celone","year":"2016","journal-title":"Acta Trop."},{"key":"2025073102543314200_qxaf136-B27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fitd.2022.998276","article-title":"A coordinated response to the needs of the learner: how deworming and school meals together will contribute to the global recovery from the COVID-19 pandemic","volume":"3","author":"Karutu","year":"2022","journal-title":"Front Trop Dis"},{"issue":"7","key":"2025073102543314200_qxaf136-B28","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1016\/j.pt.2020.04.012","article-title":"Schistosomiasis control: leave no age group behind","volume":"36","author":"Faust","year":"2020","journal-title":"Trends Parasitol"},{"issue":"6","key":"2025073102543314200_qxaf136-B29","doi-asserted-by":"publisher","first-page":"e0009405","DOI":"10.1371\/journal.pntd.0009405","article-title":"Diagnosing point-of-care diagnostics for neglected tropical diseases","volume":"15","author":"Bharadwaj","year":"2021","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"2025073102543314200_qxaf136-B30","doi-asserted-by":"publisher","first-page":"e0009088","DOI":"10.1371\/journal.pntd.0009088","article-title":"Community-directed distributors\u2014the \u201cfoot soldiers\u201d in the fight to control and eliminate neglected tropical diseases","volume":"15","author":"Amazigo","year":"2021","journal-title":"PLoS Negl Trop Dis"}],"container-title":["Health Affairs Scholar"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/healthaffairsscholar\/article-pdf\/3\/7\/qxaf136\/63897639\/qxaf136.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/healthaffairsscholar\/article-pdf\/3\/7\/qxaf136\/63897639\/qxaf136.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T06:54:37Z","timestamp":1753944877000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/healthaffairsscholar\/article\/doi\/10.1093\/haschl\/qxaf136\/8219720"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,1]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/haschl\/qxaf136","relation":{},"ISSN":["2976-5390"],"issn-type":[{"value":"2976-5390","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,7]]},"published":{"date-parts":[[2025,7,1]]},"article-number":"qxaf136"}}