{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T19:44:04Z","timestamp":1793907844873,"version":"4.8.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T00:00:00Z","timestamp":1625184000000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fogarty International Center and National Institute of Mental Health, of the National Institutes of Health","award":["D43 TW010543"],"award-info":[{"award-number":["D43 TW010543"]}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["Improving Data, Systems, and Methods for Estima"],"award-info":[{"award-number":["Improving Data, Systems, and Methods for Estima"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>An increasing focus on the use of the results of cost analyses and other economic evaluations in health programme decision-making by governments, donors and technical support partners working in low- and middle-income countries is accompanied by recognition that this use is impeded by several factors, including the lack of skills, data and coordination between spheres of the government. We describe our experience generating economic evaluation data for human immunodeficiency virus, tuberculosis and sexual\/reproductive health programmes in South Africa alongside the results of a series of in-depth interviews (IDIs) among decision-makers within the South African government and implementing organizations (data users) and producers of economic evaluations (data producers). We summarize results across (1) the process of implementing a new intervention; (2) barriers to the use of cost data and suggested solutions and (3) the transferability of experiences to the planned South African implementation of universal health coverage (UHC). Based on our experience and the IDIs, we suggest concrete steps towards the improvement of economic data use in the planning and the establishment of structures mandated under the transition to UHC. Our key recommendations include the following: (1) compile a publicly available and regularly updated in-country cost repository; (2) increase the availability of programmatic outcomes data at the aggregate level; (3) agree upon and implement a set of primary decision criteria for the adoption and funding of interventions; (4) combine the efforts of health economics institutions into a stringent system for health technology assessments and (5) improve the link between national and provincial planning and budgeting.<\/jats:p>","DOI":"10.1093\/heapol\/czab071","type":"journal-article","created":{"date-parts":[[2021,6,13]],"date-time":"2021-06-13T19:06:35Z","timestamp":1623611195000},"page":"1545-1551","source":"Crossref","is-referenced-by-count":5,"title":["Role of data from cost and other economic analyses in healthcare decision-making for HIV, TB and sexual\/reproductive health programmes in South Africa"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5466-3131","authenticated-orcid":false,"given":"Joshua P","family":"Murphy","sequence":"first","affiliation":[{"name":"Health Economics and Epidemiology Research Office (HE2RO), University of the Witwatersrand, 39 Empire Rd, Johannesburg 2193, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Kgowedi","sequence":"additional","affiliation":[{"name":"Health Economics and Epidemiology Research Office (HE2RO), University of the Witwatersrand, 39 Empire Rd, Johannesburg 2193, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nalini","family":"Naidoo","sequence":"additional","affiliation":[{"name":"Health Economics and Epidemiology Research Office (HE2RO), University of the Witwatersrand, 39 Empire Rd, Johannesburg 2193, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Girdwood","sequence":"additional","affiliation":[{"name":"Health Economics and Epidemiology Research Office (HE2RO), University of the Witwatersrand, 39 Empire Rd, Johannesburg 2193, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Jamieson","sequence":"additional","affiliation":[{"name":"Health Economics and Epidemiology Research Office (HE2RO), University of the Witwatersrand, 39 Empire Rd, Johannesburg 2193, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dj\u00f8ra","family":"Soeteman","sequence":"additional","affiliation":[{"name":"Center for Health Decision Science, Harvard T.H. Chan School of Public Health, 718 Huntington Ave, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Resch","sequence":"additional","affiliation":[{"name":"Center for Health Decision Science, Harvard T.H. Chan School of Public Health, 718 Huntington Ave, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gesine","family":"Meyer-Rath","sequence":"additional","affiliation":[{"name":"Health Economics and Epidemiology Research Office (HE2RO), University of the Witwatersrand, 39 Empire Rd, Johannesburg 2193, South Africa"},{"name":"Department of Global Health, School of Public Health, Boston University, 801 Massachusetts Ave, Boston, MA 02118, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,6,29]]},"reference":[{"key":"2021111717582201500_R1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.jval.2017.10.003","article-title":"The development of the Guide to Economic Analysis and Research (GEAR) online resource for low- and middle-income countries\u2019 health economics practitioners: a commentary","volume":"21","author":"Adeagbo","year":"2018","journal-title":"Value Health"},{"key":"2021111717582201500_R2","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1093\/heapol\/czz085","article-title":"Mental health system costs, resources and constraints in South Africa: a national survey","volume":"34","author":"Docrat","year":"2019","journal-title":"Health Policy and Planning"},{"key":"2021111717582201500_R3","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1002\/hec.683","article-title":"Cost data for individual patients included in clinical studies: no amount of statistical analysis can compensate for inadequate costing methods","volume":"11","author":"Graves","year":"2002","journal-title":"Health Economics"},{"key":"2021111717582201500_R4","first-page":"149","article-title":"Cost data assessment in multinational economic evaluations: some theory and review of published studies","volume":"2","author":"Halliday","year":"2003","journal-title":"Applied Health Economics and Health Policy"},{"key":"2021111717582201500_R5","doi-asserted-by":"crossref","first-page":"635","DOI":"10.2165\/10899570-000000000-00000","article-title":"Estimating drug costs in economic evaluations in Ireland and the UK: an analysis of practice and research recommendations","volume":"27","author":"Hughes","year":"2009","journal-title":"Pharmacoeconomics"},{"key":"2021111717582201500_R6","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.f1049","article-title":"Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement","volume":"346","author":"Husereau","year":"2013","journal-title":"BMJ"},{"key":"2021111717582201500_R7","first-page":"172","article-title":"Criteria for priority-setting in health care in Uganda: exploration of stakeholders\u2019 values","volume":"82","author":"Kapiriri","year":"2004","journal-title":"Bulletin of the World Health Organization"},{"key":"2021111717582201500_R8","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.jval.2017.12.016","article-title":"Use and misuse of cost-effectiveness analysis thresholds in low- and middle-income countries: trends in cost-per-DALY studies","volume":"21","author":"Leech","year":"2018","journal-title":"Value Health"},{"key":"2021111717582201500_R9","author":"Measure Evaluation","year":"2019"},{"key":"2021111717582201500_R10","article-title":"Guidelines for pharmacoeconomic submissions","volume-title":"Government Gazette 36118, February 2013","author":"National Department of Health","year":"2012"},{"key":"2021111717582201500_R11","doi-asserted-by":"crossref","DOI":"10.1186\/s12913-016-1946-9","article-title":"Selection of essential medicines for South Africa - 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