{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T13:44:43Z","timestamp":1791121483862,"version":"4.1.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Molecular Genetics"],"published-print":{"date-parts":[[1998,11,1]]},"DOI":"10.1093\/hmg\/7.12.1887","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T22:20:49Z","timestamp":1027722049000},"page":"1887-1892","source":"Crossref","is-referenced-by-count":110,"title":["Risk for Alzheimer's disease correlates with transcriptional activity of the APOE gene"],"prefix":"10.1093","volume":"7","author":[{"given":"M. J.","family":"Artiga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. J.","family":"Bullido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Frank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Sastre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Recuero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. L.","family":"Lendon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. W.","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Vazquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Goate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Valdivieso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"issue":"6311","key":"1_9403179","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1038\/349704a0","volume":"349","author":"Goate","year":"1991","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"6534","key":"2_15924457","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1038\/375754a0","volume":"375","author":"Sherrington","year":"1995","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"5226","key":"3_15970312","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1126\/science.7638622","volume":"269","author":"Levy-Lahad","year":"1995","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"5123","key":"4_14410788","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1126\/science.8346443","volume":"261","author":"Corder","year":"1993","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"2","key":"5_5887435","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/S0014-5793(97)01543-3","volume":"421","author":"Artiga","year":"1998","journal-title":"FEBS Letters","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3468","issn-type":"print"},{"issue":"1","key":"6_16293909","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1212\/WNL.47.1.196","volume":"47","author":"Mui","year":"1996","journal-title":"Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0028-3878","issn-type":"print"},{"issue":"1","key":"7_5847889","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/ng0198-69","volume":"18","author":"Bullido","year":"1998","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"3","key":"8_37683092","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1093\/hmg\/7.3.533","volume":"7","year":"1998","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"3","key":"9_9961151","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1002\/gepi.1370090302","volume":"9","author":"Gerdes","year":"1992","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"issue":"2","key":"10_16708629","first-page":"253","volume":"69","author":"Lucotte","year":"1997","journal-title":"Human biology; an international record of research","ISSN":"https:\/\/id.crossref.org\/issn\/0018-7143","issn-type":"print"},{"key":"11_26130324","first-page":"1349","volume":"278","year":"1997","journal-title":"A METAANALYSIS APOE AND ALZHEIMER DISEASE META ANALYSIS CONSORTIUM J AM MED ASSOC"},{"key":"12_37684117","doi-asserted-by":"crossref","first-page":"6474","DOI":"10.1021\/bi00525a028","volume":"20","year":"1981","ISSN":"https:\/\/id.crossref.org\/issn\/1520-4995","issn-type":"print"},{"issue":"4","key":"13_13166076","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1016\/S0021-9258(17)43322-9","volume":"259","author":"Reue","year":"1984","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"1","key":"14_13420513","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1073\/pnas.82.1.203","volume":"82","author":"Elshourbagy","year":"1985","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"2","key":"15_13529670","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/0003-9861(85)90704-0","volume":"239","author":"Kayden","year":"1985","journal-title":"Archives of Biochemistry and Biophysics","ISSN":"https:\/\/id.crossref.org\/issn\/1096-0384","issn-type":"print"},{"issue":"26","key":"16_5009672","doi-asserted-by":"crossref","first-page":"13340","DOI":"10.1016\/S0021-9258(18)37710-X","volume":"263","author":"Paik","year":"1988","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"17","key":"17_4918979","doi-asserted-by":"crossref","first-page":"8300","DOI":"10.1016\/S0021-9258(18)68477-7","volume":"263","author":"Smith","year":"1988","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"26","key":"18_15923117","doi-asserted-by":"publisher","first-page":"15447","DOI":"10.1074\/jbc.270.26.15447","volume":"270","author":"Calnek","year":"1995","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"23","key":"19_16518790","doi-asserted-by":"crossref","first-page":"7550","DOI":"10.1523\/JNEUROSCI.16-23-07550.1996","volume":"16","author":"Garcia","year":"1996","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"8","key":"20_9789895","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.4049\/jimmunol.148.8.2591","volume":"148","author":"Sloan","year":"1992","journal-title":"The Journal of Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"26","key":"21_15536660","doi-asserted-by":"crossref","first-page":"17371","DOI":"10.1016\/S0021-9258(17)32445-6","volume":"269","author":"Angotti","year":"1994","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"key":"22_37684118","first-page":"1796","volume":"89","year":"1992","journal-title":"ASSOCIATION OF THE MINOR ALLELE WITH DECREASED PRODUCTION RATE IN VIVO AND PROMOTER ACTIVITY IN VITRO J CLIN INVEST"},{"key":"23_37684119","first-page":"56","volume":"129","year":"1995","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"12","key":"24_37686171","doi-asserted-by":"publisher","first-page":"2151","DOI":"10.1093\/hmg\/6.12.2151","volume":"6","year":"1997","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"1","key":"25_16709641","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/S0304-3940(97)13394-8","volume":"223","author":"Taddei","year":"1997","journal-title":"Neuroscience letters","ISSN":"https:\/\/id.crossref.org\/issn\/0304-3940","issn-type":"print"},{"issue":"2","key":"26_16844526","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1172\/JCI119536","volume":"100","author":"LaFerla","year":"1997","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"1","key":"27_16377241","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/ng0996-55","volume":"14","author":"Miyata","year":"1996","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"3","key":"28_5784081","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/ng1197-263","volume":"17","author":"Bales","year":"1997","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"5-6","key":"29_16590099","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/S0301-0082(96)00038-X","volume":"50","author":"Masliah","year":"1996","journal-title":"Progress in neurobiology","ISSN":"https:\/\/id.crossref.org\/issn\/0301-0082","issn-type":"print"},{"issue":"3","key":"30_5165164","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1172\/JCI113943","volume":"83","author":"Boyles","year":"1989","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"2","key":"31_15897087","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1097\/00041433-199504000-00005","volume":"6","author":"Mahley","year":"1995","journal-title":"Current opinion in lipidology","ISSN":"https:\/\/id.crossref.org\/issn\/0957-9672","issn-type":"print"},{"key":"32_37684120","first-page":"251","volume":"36","year":"1995","journal-title":"Experimental neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0014-4886","issn-type":"print"},{"issue":"3","key":"33_15492015","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1006\/bbrc.1994.1576","volume":"200","author":"Hartmann","year":"1994","journal-title":"Biochemical and biophysical research communications","ISSN":"https:\/\/id.crossref.org\/issn\/0006-291X","issn-type":"print"},{"issue":"9","key":"34_5968205","doi-asserted-by":"crossref","first-page":"3261","DOI":"10.1523\/JNEUROSCI.18-09-03261.1998","volume":"18","author":"Sun","year":"1998","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"22","key":"35_6008444","doi-asserted-by":"publisher","first-page":"13452","DOI":"10.1074\/jbc.273.22.13452","volume":"273","author":"Ji","year":"1998","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"7","key":"36_13254183","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","volume":"34","author":"McKhann","year":"1984","journal-title":"Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0028-3878","issn-type":"print"},{"issue":"3","key":"38_5643490","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0022-2275(20)43176-1","volume":"31","author":"Hixson","year":"1990","journal-title":"The Journal of Lipid Research","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2275","issn-type":"print"},{"issue":"8910","key":"39_15502991","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1016\/S0140-6736(94)92557-7","volume":"343","author":"Talbot","year":"1994","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"6632","key":"41_4939478","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1136\/bmj.296.6632.1313","volume":"296","author":"Morris","year":"1988","journal-title":"BMJ","ISSN":"https:\/\/id.crossref.org\/issn\/0959-8138","issn-type":"print"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/7\/12\/1887\/1557432\/7-12-1887.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T03:27:56Z","timestamp":1682220476000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/7.12.1887"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,11,1]]},"references-count":39,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1998,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/7.12.1887","relation":{},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,11,1]]}}}