{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T20:08:38Z","timestamp":1772136518237,"version":"3.50.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,11,1]]},"DOI":"10.1093\/hmg\/ddm221","type":"journal-article","created":{"date-parts":[[2007,8,25]],"date-time":"2007-08-25T01:15:51Z","timestamp":1188004551000},"page":"2640-2646","source":"Crossref","is-referenced-by-count":72,"title":["Increased expression of Grainyhead-like-3 rescues spina bifida in a folate-resistant mouse model"],"prefix":"10.1093","volume":"16","author":[{"given":"Peter","family":"Gustavsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas D.E.","family":"Greene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Lad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erwin","family":"Pauws","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra C.P.","family":"de Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Stanier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Copp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2007,8,24]]},"reference":[{"key":"key\n\t\t\t\t20170522141233_DDM221C1","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1038\/nrg1181","article-title":"The genetic basis of mammalian neurulation","volume":"4","author":"Copp","year":"2003","journal-title":"Nat. Rev. Genet."},{"key":"key\n\t\t\t\t20170522141233_DDM221C2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s004290100169","article-title":"Curly tail: a 50-year history of the mouse spina bifida model","volume":"203","author":"Van Straaten","year":"2001","journal-title":"Anat. Embryol."},{"key":"key\n\t\t\t\t20170522141233_DDM221C3","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/bdra.20333","article-title":"Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects","volume":"79","author":"Harris","year":"2007","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"key\n\t\t\t\t20170522141233_DDM221C4","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/nm0197-60","article-title":"Inositol prevents folate-resistant neural tube defects in the mouse","volume":"3","author":"Greene","year":"1997","journal-title":"Nature Med."},{"key":"key\n\t\t\t\t20170522141233_DDM221C5","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1093\/humrep\/17.9.2451","article-title":"D- chiro -inositol is more effective than myo -inositol in preventing folate-resistant mouse neural tube defects","volume":"17","author":"Cogram","year":"2002","journal-title":"Hum. Reprod."},{"key":"key\n\t\t\t\t20170522141233_DDM221C6","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/hmg\/ddh003","article-title":"Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol","volume":"13","author":"Cogram","year":"2004","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522141233_DDM221C7","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/ajmg.c.30051","article-title":"Mouse models of neural tube defects: investigating preventive mechanisms","volume":"135","author":"Greene","year":"2005","journal-title":"Am. J. Med. Genet. C. Semin. Med. Genet."},{"key":"key\n\t\t\t\t20170522141233_DDM221C8","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/BF02981490","article-title":"Genetical studies on the skeleton of the mouse. VIII. Curly tail","volume":"52","author":"Gruneberg","year":"1954","journal-title":"J. Genet."},{"key":"key\n\t\t\t\t20170522141233_DDM221C9","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1242\/dev.113.2.671","article-title":"Curvature of the caudal region is responsible for failure of neural tube closure in the curly tail (ct) mouse embryo","volume":"113","author":"Brook","year":"1991","journal-title":"Development"},{"key":"key\n\t\t\t\t20170522141233_DDM221C10","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1242\/dev.104.2.285","article-title":"A cell-type-specific abnormality of cell proliferation in mutant (curly tail) mouse embryos developing spinal neural tube defects","volume":"104","author":"Copp","year":"1988","journal-title":"Development"},{"key":"key\n\t\t\t\t20170522141233_DDM221C11","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/ng0494-357","article-title":"Multifactorial inheritance of neural tube defects: Localization of the major gene and recognition of modifiers in ct mutant mice","volume":"6","author":"Neumann","year":"1994","journal-title":"Nature Genet."},{"key":"key\n\t\t\t\t20170522141233_DDM221C12","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1002\/bdra.20109","article-title":"Toward positional cloning of the curly tail gene","volume":"73","author":"Brouns","year":"2005","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"key\n\t\t\t\t20170522141233_DDM221C13","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1042\/bj20021476","article-title":"The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors","volume":"370","author":"Ting","year":"2003","journal-title":"Biochem. J."},{"key":"key\n\t\t\t\t20170522141233_DDM221C14","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/dvdy.10255","article-title":"Identification and characterization of Grainyhead-like epithelial transactivator (GET-1), a novel mammalian Grainyhead-like factor","volume":"226","author":"Kudryavtseva","year":"2003","journal-title":"Dev. Dyn."},{"key":"key\n\t\t\t\t20170522141233_DDM221C15","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1038\/nm961","article-title":"Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3","volume":"9","author":"Ting","year":"2003","journal-title":"Nature Med."},{"key":"key\n\t\t\t\t20170522141233_DDM221C16","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.ydbio.2006.07.015","article-title":"The Grainyhead-like epithelial transactivator Get-1\/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4","volume":"299","author":"Yu","year":"2006","journal-title":"Dev. Biol."},{"key":"key\n\t\t\t\t20170522141233_DDM221C17","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1242\/dev.119.1.113","article-title":"Interaction between splotch ( Sp ) and curly tail ( ct ) mouse mutants in the embryonic development of neural tube defects","volume":"119","author":"Estibeiro","year":"1993","journal-title":"Development"},{"key":"key\n\t\t\t\t20170522141233_DDM221C18","doi-asserted-by":"crossref","first-page":"206","DOI":"10.3171\/spi.2003.99.2.0206","article-title":"Tethering of the spinal cord in mouse fetuses and neonates with spina bifida","volume":"99","author":"Stiefel","year":"2003","journal-title":"J. Neurosurg. (Spine)"},{"key":"key\n\t\t\t\t20170522141233_DDM221C19","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1006\/geno.1995.9946","article-title":"A curly-tail modifier locus, mct1, on mouse chromosome 17","volume":"29","author":"Letts","year":"1995","journal-title":"Genomics"},{"key":"key\n\t\t\t\t20170522141233_DDM221C20","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.modgep.2006.03.011","article-title":"Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development","volume":"6","author":"Auden","year":"2006","journal-title":"Gene Expr. Patterns."},{"key":"key\n\t\t\t\t20170522141233_DDM221C21","first-page":"39","article-title":"Relationship between timing of posterior neuropore closure and development of spinal neural tube defects in mutant (curly tail) and normal mouse embryos in culture","volume":"88","author":"Copp","year":"1985","journal-title":"J. Embryol. Exp. Morphol."},{"key":"key\n\t\t\t\t20170522141233_DDM221C22","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1136\/jmg.39.2.e5","article-title":"Inositol and folate-resistant neural tube defects","volume":"39","author":"Cavalli","year":"2002","journal-title":"J. Med. Genet."},{"key":"key\n\t\t\t\t20170522141233_DDM221C23","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1126\/science.1107511","article-title":"A homolog of Drosophila grainy head is essential for epidermal integrity in mice","volume":"308","author":"Ting","year":"2005","journal-title":"Science"},{"key":"key\n\t\t\t\t20170522141233_DDM221C24","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/ajmg.c.30048","article-title":"Candidate gene analysis in human neural tube defects","volume":"135","author":"Boyles","year":"2005","journal-title":"Am. J. Med. Genet. C. Semin. Med. Genet."},{"key":"key\n\t\t\t\t20170522141233_DDM221C25","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1002\/dvdy.20383","article-title":"Expression pattern of glypican-4 suggests multiple roles during mouse development","volume":"233","author":"Ybot-Gonzalez","year":"2005","journal-title":"Dev. Dyn."}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/16\/21\/2640\/17244239\/ddm221.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,22]],"date-time":"2021-08-22T10:22:05Z","timestamp":1629627725000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddm221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,24]]},"references-count":25,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2007,8,24]]},"published-print":{"date-parts":[[2007,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddm221","relation":{},"ISSN":["1460-2083","0964-6906"],"issn-type":[{"value":"1460-2083","type":"electronic"},{"value":"0964-6906","type":"print"}],"subject":[],"published":{"date-parts":[[2007,8,24]]}}}