{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T21:27:25Z","timestamp":1783114045794,"version":"3.54.6"},"reference-count":68,"publisher":"Oxford University Press (OUP)","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,12,1]]},"DOI":"10.1093\/hmg\/ddm244","type":"journal-article","created":{"date-parts":[[2007,8,31]],"date-time":"2007-08-31T00:18:07Z","timestamp":1188519487000},"page":"2854-2869","source":"Crossref","is-referenced-by-count":58,"title":["Genetic association of CTNNA3 with late-onset Alzheimer's disease in females"],"prefix":"10.1093","volume":"16","author":[{"given":"Akinori","family":"Miyashita","sequence":"first","affiliation":[{"name":"Bioresource Science Branch, Center for Bioresources, Brain Research Institute, Niigata University, Niigata 951-8585, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and Gerontology, Center for Asian Traditional Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Asada","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tsukuba 305-8575, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Imagawa","sequence":"additional","affiliation":[{"name":"Imagawa Clinic, Fukushima-ku, Osaka 553-0003, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etsuro","family":"Matsubara","sequence":"additional","affiliation":[{"name":"Department of Alzheimer's Disease Research, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu 474-8522, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikio","family":"Shoji","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neuroscience and Biophysiological Science, Hirosaki University, School of Medicine, Hirosaki 036-8562, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susumu","family":"Higuchi","sequence":"additional","affiliation":[{"name":"Division of Clinical Research, Kurihama Alcoholism Center, National Hospital Organization, Yokosuka 239-0841, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuya","family":"Urakami","sequence":"additional","affiliation":[{"name":"Department of Biological Regulation, Section of Environment and Health Science, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiyoshi","family":"Kakita","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Pathological Neuroscience, Brain Research Institute, Niigata University, Niigata 951-8585, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Pathological Neuroscience, Brain Research Institute, Niigata University, Niigata 951-8585, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Toyabe","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Niigata University, Niigata 951-8520, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Akazawa","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Niigata University, Niigata 951-8520, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Kanazawa","sequence":"additional","affiliation":[{"name":"National Center for Neurology and Psychiatry, Kodaira 187-8502, Japan and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Ihara","sequence":"additional","affiliation":[{"name":"Department of Neuropathology, Faculty of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryozo","family":"Kuwano","sequence":"additional","affiliation":[{"name":"Bioresource Science Branch, Center for Bioresources, Brain Research Institute, Niigata University, Niigata 951-8585, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"The Japanese Genetic Study Consortium for Alzeheimer's Disease","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2007,8,30]]},"reference":[{"key":"key\n\t\t\t\t20180328134447_DDM244C1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1212\/WNL.42.1.115","article-title":"Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham Study","volume":"42","author":"Bachman","year":"1992","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20180328134447_DDM244C2","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1212\/WNL.55.2.198","article-title":"Prevalence of AD among whites: a summary by levels of severity","volume":"55","author":"Hy","year":"2000","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20180328134447_DDM244C3","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1479-8301.2003.00020.x","article-title":"Prevalence and predominance of Alzheimer type dementia in rural Japan","volume":"3","author":"Nakamura","year":"2003","journal-title":"Psychogeriatrics"},{"key":"key\n\t\t\t\t20180328134447_DDM244C4","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1212\/WNL.53.9.1992","article-title":"Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group","volume":"53","author":"Andersen","year":"1999","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20180328134447_DDM244C5","first-page":"S10","article-title":"Incidence of dementia and major subtypes in Europe: a collaborative study of population-based cohorts","volume":"54","author":"Fratiglioni","year":"2000","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20180328134447_DDM244C6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1749-6632.2002.tb04793.x","article-title":"Incidence and risk factors of dementia in a defined elderly Japanese population: the Hisayama study","volume":"977","author":"Fujishima","year":"2002","journal-title":"Ann. NY Acad. Sci."},{"key":"key\n\t\t\t\t20180328134447_DDM244C7","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1001\/archneur.59.11.1737","article-title":"Dementia and Alzheimer disease incidence: a prospective cohort study","volume":"59","author":"Kukull","year":"2002","journal-title":"Arch. Neurol."},{"key":"key\n\t\t\t\t20180328134447_DDM244C8","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1001\/archneur.59.10.1589","article-title":"Dementia and Alzheimer disease incidence rates do not vary by sex in Rochester, Minn","volume":"59","author":"Edland","year":"2002","journal-title":"Arch. Neurol."},{"key":"key\n\t\t\t\t20180328134447_DDM244C9","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1023\/A:1022597616872","article-title":"Sex differences in genetic risk for dementia","volume":"33","author":"Gatz","year":"2003","journal-title":"Behav. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C10","article-title":"Transcriptional profiling of Alzheimer blood mononuclear cells by microarray","author":"Maes","year":"2006","journal-title":"Neurobiol. Aging"},{"key":"key\n\t\t\t\t20180328134447_DDM244C11","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1212\/01.WNL.0000137040.64252.ED","article-title":"Plasma levels of amyloid beta-protein 42 are increased in women with mild cognitive impairment","volume":"63","author":"Assini","year":"2004","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20180328134447_DDM244C12","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.nbd.2003.08.009","article-title":"Gender differences in the amount and deposition of amyloid beta in APPswe and PS1 double transgenic mice","volume":"14","author":"Wang","year":"2003","journal-title":"Neurobiol. Dis."},{"key":"key\n\t\t\t\t20180328134447_DDM244C13","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.nbd.2006.05.010","article-title":"Deposition of mouse amyloid beta in human APP\/PS1 double and single AD model transgenic mice","volume":"23","author":"van Groen","year":"2006","journal-title":"Neurobiol. Dis."},{"key":"key\n\t\t\t\t20180328134447_DDM244C14","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.jinorgbio.2006.02.010","article-title":"Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology","volume":"100","author":"Maynard","year":"2006","journal-title":"J. Inorg. Biochem."},{"key":"key\n\t\t\t\t20180328134447_DDM244C15","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s00702-006-0580-9","article-title":"Gender dependent APP processing in a transgenic mouse model of Alzheimer's disease","volume":"114","author":"Schafer","year":"2007","journal-title":"J. Neural Transm."},{"key":"key\n\t\t\t\t20180328134447_DDM244C16","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/(SICI)1098-2272(1997)14:2<169::AID-GEPI6>3.0.CO;2-2","article-title":"Gender-specific nonrandom association between the alpha 1-antichymotrypsin and apolipoprotein E polymorphisms in the general population and its implication for the risk of Alzheimer's disease","volume":"14","author":"Kamboh","year":"1997","journal-title":"Genet. Epidemiol."},{"key":"key\n\t\t\t\t20180328134447_DDM244C17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1006\/exnr.1998.6977","article-title":"Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease","volume":"155","author":"Reynolds","year":"1999","journal-title":"Exp. Neurol."},{"key":"key\n\t\t\t\t20180328134447_DDM244C18","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1006\/exnr.2000.7560","article-title":"Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase gene","volume":"167","author":"Crawford","year":"2001","journal-title":"Exp. Neurol."},{"key":"key\n\t\t\t\t20180328134447_DDM244C19","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0304-3940(00)00791-6","article-title":"Gender-specific association of the angiotensin converting enzyme gene with Alzheimer's disease","volume":"280","author":"Crawford","year":"2000","journal-title":"Neurosci. Lett."},{"key":"key\n\t\t\t\t20180328134447_DDM244C20","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1038\/sj.ejhg.5201447","article-title":"Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women","volume":"13","author":"Pirskanen","year":"2005","journal-title":"Eur. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C21","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.neulet.2006.09.005","article-title":"Association of DSC1, a gene modulated by adrenergic stimulation, with Alzheimer's disease","volume":"408","author":"Ramos","year":"2006","journal-title":"Neurosci. Lett."},{"key":"key\n\t\t\t\t20180328134447_DDM244C22","article-title":"Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease","author":"Sundar","year":"2006","journal-title":"Neurobiol. Aging"},{"key":"key\n\t\t\t\t20180328134447_DDM244C23","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1126\/science.290.5500.2303","article-title":"Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees","volume":"290","author":"Ertekin-Taner","year":"2000","journal-title":"Science"},{"key":"key\n\t\t\t\t20180328134447_DDM244C24","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1126\/science.290.5500.2304","article-title":"Susceptibility locus for Alzheimer's disease on chromosome 10","volume":"290","author":"Myers","year":"2000","journal-title":"Science"},{"key":"key\n\t\t\t\t20180328134447_DDM244C25","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1126\/science.290.5500.2302","article-title":"Evidence for genetic linkage of Alzheimer's disease to chromosome 10q","volume":"290","author":"Bertram","year":"2000","journal-title":"Science"},{"key":"key\n\t\t\t\t20180328134447_DDM244C26","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1093\/hmg\/ddl142","article-title":"Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease","volume":"15","author":"Kuwano","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C27","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/ajmg.10648","article-title":"Evidence for parent of origin effect in late-onset Alzheimer disease","volume":"114","author":"Bassett","year":"2002","journal-title":"Am. J. Med. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C28","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/ajmg.b.30350","article-title":"Further evidence of a maternal parent-of-origin effect on chromosome 10 in late-onset Alzheimer's disease","volume":"141","author":"Bassett","year":"2006","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet"},{"key":"key\n\t\t\t\t20180328134447_DDM244C29","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1242\/jcs.114.17.3177","article-title":"AlphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion","volume":"114","author":"Janssens","year":"2001","journal-title":"J. Cell. Sci."},{"key":"key\n\t\t\t\t20180328134447_DDM244C30","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s00439-002-0857-5","article-title":"Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy","volume":"112","author":"Janssens","year":"2003","journal-title":"Hum. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C31","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/27208","article-title":"Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis","volume":"395","author":"Zhang","year":"1998","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180328134447_DDM244C32","doi-asserted-by":"crossref","first-page":"3133","DOI":"10.1093\/hmg\/ddg343","article-title":"Fine mapping of the alpha-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees","volume":"12","author":"Ertekin-Taner","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C33","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1385\/NMM:5:2:133","article-title":"Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease","volume":"5","author":"Busby","year":"2004","journal-title":"Neuromolecular Med."},{"key":"key\n\t\t\t\t20180328134447_DDM244C34","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.neulet.2004.01.032","article-title":"Genetic variation in CTNNA3 encoding alpha-3 catenin and Alzheimer's disease","volume":"358","author":"Blomqvist","year":"2004","journal-title":"Neurosci. Lett."},{"key":"key\n\t\t\t\t20180328134447_DDM244C35","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1136\/jmg.2004.029553","article-title":"Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease","volume":"42","author":"Martin","year":"2005","journal-title":"J. Med. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C36","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/01.wad.0000189030.50826.86","article-title":"Insulin degrading enzyme and alpha-3 catenin polymorphisms in Italian patients with Alzheimer disease","volume":"19","author":"Cellini","year":"2005","journal-title":"Alzheimer Dis. Assoc. Disord."},{"key":"key\n\t\t\t\t20180328134447_DDM244C37","doi-asserted-by":"crossref","first-page":"e63","DOI":"10.1136\/jmg.2005.039263","article-title":"Is alpha-T catenin (VR22) an Alzheimer's disease risk gene?","volume":"44","author":"Bertram","year":"2007","journal-title":"J. Med. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C38","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1038\/nature04226","article-title":"A haplotype map of the human genome","volume":"437","author":"International HapMap Consortium","year":"2005","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180328134447_DDM244C39","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0014-5793(98)00886-2","article-title":"Direct association of presenilin-1 with beta-catenin","volume":"433","author":"Murayama","year":"1998","journal-title":"FEBS Lett."},{"key":"key\n\t\t\t\t20180328134447_DDM244C40","doi-asserted-by":"crossref","first-page":"16470","DOI":"10.1074\/jbc.273.26.16470","article-title":"The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin","volume":"273","author":"Yu","year":"1998","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20180328134447_DDM244C41","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/5526","article-title":"Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex","volume":"5","author":"Nishimura","year":"1999","journal-title":"Nat. Med."},{"key":"key\n\t\t\t\t20180328134447_DDM244C42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0165-0173(00)00021-7","article-title":"Wnt signaling function in Alzheimer's disease","volume":"33","author":"De Ferrari","year":"2000","journal-title":"Brain Res. Rev."},{"key":"key\n\t\t\t\t20180328134447_DDM244C43","doi-asserted-by":"crossref","first-page":"7545","DOI":"10.1038\/sj.onc.1210064","article-title":"The ups and downs of Wnt signaling in prevalent neurological disorders","volume":"25","author":"De Ferrari","year":"2006","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20180328134447_DDM244C44","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/ng1267","article-title":"An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis","volume":"35","author":"Tokuhiro","year":"2003","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C45","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/nature05329","article-title":"Global variation in copy number in the human genome","volume":"444","author":"Redon","year":"2006","journal-title":"Nature"},{"issue":"Spec. No. 1","key":"key\n\t\t\t\t20180328134447_DDM244C46","doi-asserted-by":"crossref","first-page":"R57","DOI":"10.1093\/hmg\/ddl057","article-title":"Structural variants: changing the landscape of chromosomes and design of disease studies","volume":"15","author":"Feuk","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C47","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.modgep.2004.06.006","article-title":"Differential downregulation of alphaT-catenin expression in placenta: trophoblast cell type-dependent imprinting of the CTNNA3 gene","volume":"5","author":"van Dijk","year":"2004","journal-title":"Gene Expr. Patterns"},{"key":"key\n\t\t\t\t20180328134447_DDM244C48","doi-asserted-by":"crossref","first-page":"D548","DOI":"10.1093\/nar\/gkh093","article-title":"EICO (Expression-based Imprint Candidate Organizer): finding disease-related imprinted genes","volume":"32","author":"Nikaido","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20180328134447_DDM244C49","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1101\/gr.1055303","article-title":"Discovery of imprinted transcripts in the mouse transcriptome using large-scale expression profiling","volume":"13","author":"Nikaido","year":"2003","journal-title":"Genome Res."},{"key":"key\n\t\t\t\t20180328134447_DDM244C50","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1101\/gr.3303505","article-title":"Genome-wide prediction of imprinted murine genes","volume":"15","author":"Luedi","year":"2005","journal-title":"Genome Res."},{"key":"key\n\t\t\t\t20180328134447_DDM244C51","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S1364-6613(00)01504-7","article-title":"Imprinted genes, cognition and behaviour","volume":"4","author":"Isles","year":"2000","journal-title":"Trends Cogn. Sci."},{"key":"key\n\t\t\t\t20180328134447_DDM244C52","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.tig.2005.06.008","article-title":"A census of mammalian imprinting","volume":"21","author":"Morison","year":"2005","journal-title":"Trends Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C53","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.neubiorev.2004.11.007","article-title":"Imprinted gene expression in the brain","volume":"29","author":"Davies","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"key\n\t\t\t\t20180328134447_DDM244C54","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1038\/ng1047","article-title":"Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction","volume":"32","author":"Ozaki","year":"2002","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C55","doi-asserted-by":"crossref","first-page":"15688","DOI":"10.1073\/pnas.0403535101","article-title":"Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family","volume":"101","author":"Li","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20180328134447_DDM244C56","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1086\/498851","article-title":"A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease","volume":"78","author":"Grupe","year":"2006","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C57","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1093\/hmg\/ddl178","article-title":"DAPK1 variants are associated with Alzheimer's disease and allele-specific expression","volume":"15","author":"Li","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C58","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s10038-004-0205-9","article-title":"Designing a multistage, SNP-based, genome screen for common diseases","volume":"49","author":"Sato","year":"2004","journal-title":"J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328134447_DDM244C59","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1126\/science.8191290","article-title":"An increased percentage of long amyloid \u03b2 protein secreted by familial amyloid \u03b2 protein precursor (\u03b2APP717) mutants","volume":"264","author":"Suzuki","year":"1994","journal-title":"Science"},{"key":"key\n\t\t\t\t20180328134447_DDM244C60","doi-asserted-by":"crossref","first-page":"10272","DOI":"10.1021\/bi00032a022","article-title":"Long amyloid \u03b2-protein secreted from wild-type human neuroblastoma IMR-32 cells","volume":"32","author":"Asami-Odaka","year":"1995","journal-title":"Biochemistry"},{"key":"key\n\t\t\t\t20180328134447_DDM244C61","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/1531-8249(199904)45:4<537::AID-ANA20>3.0.CO;2-2","article-title":"Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome","volume":"45","author":"Matsubara","year":"1999","journal-title":"Ann. Neurol."},{"key":"key\n\t\t\t\t20180328134447_DDM244C62","doi-asserted-by":"crossref","first-page":"361","DOI":"10.2307\/2532296","article-title":"Performing the exact test of Hardy\u2013Weinberg proportion for multiple alleles","volume":"48","author":"Guo","year":"1992","journal-title":"Biometrics"},{"key":"key\n\t\t\t\t20180328134447_DDM244C63","first-page":"719","article-title":"Statistical aspects of the analysis of data from retrospective studies of disease","volume":"22","author":"Mantel","year":"1959","journal-title":"J. Natl. Cancer Inst."},{"key":"key\n\t\t\t\t20180328134447_DDM244C64","first-page":"921","article-title":"Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population","volume":"12","author":"Excoffier","year":"1995","journal-title":"Mol. Biol. Evol."},{"key":"key\n\t\t\t\t20180328134447_DDM244C65","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1101\/gr.148401","article-title":"Genetic analysis of case\/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease","volume":"11","author":"Fallin","year":"2001","journal-title":"Genome Res."},{"key":"key\n\t\t\t\t20180328134447_DDM244C66","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1126\/science.1069424","article-title":"The structure of haplotype blocks in the human genome","volume":"296","author":"Gabriel","year":"2002","journal-title":"Science"},{"key":"key\n\t\t\t\t20180328134447_DDM244C67","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/bioinformatics\/bth457","article-title":"Haploview: analysis and visualization of LD and haplotype maps","volume":"21","author":"Barrett","year":"2005","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t20180328134447_DDM244C68","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1002\/(SICI)1097-0258(19970315)16:5<583::AID-SIM433>3.0.CO;2-Z","article-title":"Power of logrank test and Cox regression model in clinical trials with heterogeneous samples","volume":"16","author":"Akazawa","year":"1997","journal-title":"Stat. Med."}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/16\/23\/2854\/13938062\/ddm244.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,22]],"date-time":"2021-08-22T16:01:28Z","timestamp":1629648088000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article\/16\/23\/2854\/556408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,30]]},"references-count":68,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2007,8,30]]},"published-print":{"date-parts":[[2007,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddm244","relation":{},"ISSN":["1460-2083","0964-6906"],"issn-type":[{"value":"1460-2083","type":"electronic"},{"value":"0964-6906","type":"print"}],"subject":[],"published-other":{"date-parts":[[2007,12,1]]},"published":{"date-parts":[[2007,8,30]]}}}