{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:29:21Z","timestamp":1791318561927,"version":"4.3.1"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,12,1]]},"DOI":"10.1093\/hmg\/ddm278","type":"journal-article","created":{"date-parts":[[2007,9,28]],"date-time":"2007-09-28T20:23:49Z","timestamp":1191011029000},"page":"2972-2986","source":"Crossref","is-referenced-by-count":57,"title":["Adipose tissue mass is modulated by SLUG (SNAI2)"],"prefix":"10.1093","volume":"16","author":[{"given":"Pedro Antonio","family":"P\u00e9rez-Mancera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camino","family":"Bermejo-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00e9s","family":"Gonz\u00e1lez-Herrero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Herranz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Flores","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isidro","family":"S\u00e1nchez-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2007,9,28]]},"reference":[{"key":"key\n\t\t\t\t20170522140513_DDM278C1","doi-asserted-by":"crossref","first-page":"3116S","DOI":"10.1093\/jn\/130.12.3116S","article-title":"Hormonal signaling and transcriptional control of adipocyte differentiation","volume":"130","author":"Morrison","year":"2000","journal-title":"J. Nutr."},{"key":"key\n\t\t\t\t20170522140513_DDM278C2","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1101\/gad.14.11.1293","article-title":"Transcriptional regulation of adipogenesis","volume":"14","author":"Rosen","year":"2000","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t20170522140513_DDM278C3","doi-asserted-by":"crossref","first-page":"34167","DOI":"10.1074\/jbc.M104421200","article-title":"Distinct transcriptional profiles of adipogenesis in vivo and in vitro","volume":"276","author":"Soukas","year":"2001","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522140513_DDM278C4","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.cmet.2004.12.009","article-title":"Krox20 stimulates adipogenesis via C\/EBPbeta-dependent and -independent mechanisms","volume":"1","author":"Chen","year":"2005","journal-title":"Cell Metab."},{"key":"key\n\t\t\t\t20170522140513_DDM278C5","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.1242\/dev.125.16.3111","article-title":"Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo","volume":"125","author":"Sefton","year":"1998","journal-title":"Development"},{"key":"key\n\t\t\t\t20170522140513_DDM278C6","unstructured":"Sanchez-Martin M. Gonzalez-Herrero I. Sanchez-Garcia I. 2004 SNAI2 (SNAIL HOMOLOG 2) Atlas Genet Cytogenet Oncol Haematol. http:\/\/atlasgeneticsoncology.org\/\/Genes\/SNAI2ID453.html. April"},{"key":"key\n\t\t\t\t20170522140513_DDM278C7","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S1535-6108(02)00155-1","article-title":"Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo","volume":"2","author":"Inoue","year":"2002","journal-title":"Cancer Cell"},{"key":"key\n\t\t\t\t20170522140513_DDM278C8","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1182\/blood.V100.4.1274.h81602001274_1274_1286","article-title":"Zinc-finger transcription factor Slug contributes to the function of the stem cell factor c-kit signaling pathway","volume":"100","author":"Perez-Losada","year":"2002","journal-title":"Blood"},{"key":"key\n\t\t\t\t20170522140513_DDM278C9","doi-asserted-by":"crossref","first-page":"4205","DOI":"10.1038\/sj.onc.1206467","article-title":"The radioresistance biological function of the SCF\/kit signaling pathway is mediated by the zinc-finger transcription factor Slug","volume":"22","author":"Perez-Losada","year":"2003","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20170522140513_DDM278C10","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.1038\/sj.onc.1208505","article-title":"SLUG (SNAI2) in cancer development","volume":"24","author":"P\u00e9rez-Mancera","year":"2005","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20170522140513_DDM278C11","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1006\/geno.1998.5367","article-title":"Human SLUG gene organization, expression, and chromosome map location on 8q","volume":"51","author":"Cohen","year":"1998","journal-title":"Genomics"},{"key":"key\n\t\t\t\t20170522140513_DDM278C12","doi-asserted-by":"crossref","first-page":"3231","DOI":"10.1093\/hmg\/11.25.3231","article-title":"SLUG (SNAI2) deletions in patients with Waardenburg disease","volume":"11","author":"Sanchez-Martin","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522140513_DDM278C13","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/ar.a.10027","article-title":"Slug expression during organogenesis in mice","volume":"271A","author":"Oram","year":"2003","journal-title":"Anat. Rec."},{"key":"key\n\t\t\t\t20170522140513_DDM278C14","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/ajmg.a.20345","article-title":"Deletion of the SLUG (SNAI2) gene results in human piebaldism","volume":"122A","author":"Sanchez-Martin","year":"2003","journal-title":"Am. J. Med. Genet."},{"key":"key\n\t\t\t\t20170522140513_DDM278C15","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000091924","article-title":"SLUG (SNAI2) overexpression in embryonic development","volume":"114","author":"Perez-Mancera","year":"2006","journal-title":"Cytogenet. Genome Res."},{"key":"key\n\t\t\t\t20170522140513_DDM278C16","doi-asserted-by":"crossref","first-page":"10703","DOI":"10.1073\/pnas.0403652101","article-title":"Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity","volume":"101","author":"Zhang","year":"2004","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522140513_DDM278C17","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/0092-8674(94)90006-X","article-title":"Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor","volume":"79","author":"Tontonoz","year":"1994","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522140513_DDM278C18","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S1097-2765(00)80306-8","article-title":"Cross-regulation of C\/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity","volume":"3","author":"Wu","year":"1999","journal-title":"Mol. Cell."},{"key":"key\n\t\t\t\t20170522140513_DDM278C19","doi-asserted-by":"crossref","first-page":"18779","DOI":"10.1074\/jbc.272.30.18779","article-title":"The organization, promoter analysis, and expression of the human PPARgamma gene","volume":"272","author":"Fajas","year":"1997","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522140513_DDM278C20","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1128\/MCB.24.1.306-319.2004","article-title":"Snail mediates E-cadherin repression by the recruitment of the Sin3A\/histone deacetylase 1 (HDAC1)\/HDAC2 complex","volume":"24","author":"Peinado","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170522140513_DDM278C21","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ygeno.2005.09.014","article-title":"Mouse cDNA microarray analysis uncovers SLUG targets in mouse embryonic fibroblasts","volume":"87","author":"Bermejo-Rodr\u00edguez","year":"2006","journal-title":"Genomics"},{"key":"key\n\t\t\t\t20170522140513_DDM278C22","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0962-8924(99)01536-6","article-title":"Histone deacetylases: transcriptional repression with SINers and NuRDs","volume":"19","author":"Ayer","year":"1999","journal-title":"Trends Cell. Biol."},{"key":"key\n\t\t\t\t20170522140513_DDM278C23","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1101\/gad.5.9.1538","article-title":"Regulated expression of three C\/EBP isoforms during adipose conversion of 3T3-L1 cells","volume":"5","author":"Cao","year":"1991","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t20170522140513_DDM278C24","doi-asserted-by":"crossref","first-page":"8757","DOI":"10.1073\/pnas.91.19.8757","article-title":"CCAAT\/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program","volume":"91","author":"Lin","year":"1994","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522140513_DDM278C25","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1101\/gad.948702","article-title":"C\/EBPalpha induces adipogenesis through PPARgamma: a unified pathway","volume":"16","author":"Rosen","year":"2002","journal-title":"Genes Dev."},{"key":"key\n\t\t\t\t20170522140513_DDM278C26","doi-asserted-by":"crossref","first-page":"549","DOI":"10.4161\/cc.4.4.1564","article-title":"Histone deacetylase inhibitors in programmed cell death and cancer therapy","volume":"4","author":"Marks","year":"2005","journal-title":"Cell Cycle"},{"key":"key\n\t\t\t\t20170522140513_DDM278C27","doi-asserted-by":"crossref","first-page":"6608","DOI":"10.1074\/jbc.M508982200","article-title":"Down-regulation of histone deacetylases stimulates adipocyte differentiation","volume":"281","author":"Yoo","year":"2006","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522140513_DDM278C28","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S1097-2765(00)80336-6","article-title":"SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein","volume":"4","author":"Inukai","year":"1999","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t20170522140513_DDM278C29","doi-asserted-by":"crossref","first-page":"13264","DOI":"10.1073\/pnas.96.23.13264","article-title":"cDNA microarrays detect activation of a myogenic transcription program by the PAX3\u2013FKHR fusion gene","volume":"96","author":"Khan","year":"1999","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522140513_DDM278C30","first-page":"87","article-title":"The development of adipose tissue","volume-title":"Handbook of Physiology","author":"Wasserman","year":"1965"},{"key":"key\n\t\t\t\t20170522140513_DDM278C31","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/BF03354443","article-title":"Anatomy of the adipose organ","volume":"5","author":"Cinti","year":"2000","journal-title":"Eat. Weight Disord."},{"key":"key\n\t\t\t\t20170522140513_DDM278C32","doi-asserted-by":"crossref","DOI":"10.1146\/annurev.genet.41.110306.130146","article-title":"Function of zinc-finger transcription factor SNA12 in cancer and development","author":"Cobaleda","year":"2007","journal-title":"Annu. Rev. Genet."},{"key":"key\n\t\t\t\t20170522140513_DDM278C33","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1242\/dev.00238","article-title":"Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest","volume":"130","author":"Aybar","year":"2003","journal-title":"Development"},{"key":"key\n\t\t\t\t20170522140513_DDM278C34","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1242\/jcs.00224","article-title":"The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors","volume":"116","author":"Bolos","year":"2003","journal-title":"J. Cell. Sci."},{"key":"key\n\t\t\t\t20170522140513_DDM278C35","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0012-1606(98)80005-5","article-title":"The Slug gene is not essential for mesoderm or neural crest development in mice","volume":"198","author":"Jiang","year":"1998","journal-title":"Dev. Biol."},{"key":"key\n\t\t\t\t20170522140513_DDM278C36","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1182\/blood.V90.6.2168","article-title":"A BCR-ABL(p190) fusion gene made by homologous recombination causes B-cell acute lymphoblastic leukemias in chimeric mice with independence of the endogenous bcr product","volume":"90","author":"Castellanos","year":"1997","journal-title":"Blood"},{"key":"key\n\t\t\t\t20170522140513_DDM278C37","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1101\/gad.14.15.1920","article-title":"Translational control of C\/EBPalpha and C\/EBPbeta isoform expression","volume":"14","author":"Calkhoven","year":"2000","journal-title":"Genes Dev."}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/16\/23\/2972\/13938368\/ddm278.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,14]],"date-time":"2023-05-14T04:26:05Z","timestamp":1684038365000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddm278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9,28]]},"references-count":37,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2007,9,28]]},"published-print":{"date-parts":[[2007,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddm278","relation":{},"ISSN":["1460-2083","0964-6906"],"issn-type":[{"value":"1460-2083","type":"electronic"},{"value":"0964-6906","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9,28]]}}}