{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T01:49:12Z","timestamp":1792547352344,"version":"4.5.0"},"reference-count":69,"publisher":"Oxford University Press (OUP)","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Molecular Genetics"],"DOI":"10.1093\/hmg\/ddn147","type":"journal-article","created":{"date-parts":[[2008,5,10]],"date-time":"2008-05-10T20:27:03Z","timestamp":1210451223000},"page":"2474-2485","source":"Crossref","is-referenced-by-count":96,"title":["The Primary open-angle glaucoma gene WDR36 functions in ribosomal RNA processing and interacts with the p53 stress-response pathway"],"prefix":"10.1093","volume":"17","author":[{"given":"J. M.","family":"Skarie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. A.","family":"Link","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,5,7]]},"reference":[{"key":"1_19413426","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1146\/annurev.genom.6.080604.162209","volume":"6","author":"Libby","year":"2005","journal-title":"Annual review of genomics and human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1527-8204","issn-type":"print"},{"issue":"5","key":"2_16278750","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1136\/bjo.80.5.389","volume":"80","author":"Quigley","year":"1996","journal-title":"British Journal of Ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1161","issn-type":"print"},{"issue":"5","key":"4_18158463","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/ajcn\/79.5.755","volume":"79","author":"Kang","year":"2004","journal-title":"American Journal of Clinical Nutrition","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9165","issn-type":"print"},{"issue":"5","key":"5_30404176","doi-asserted-by":"publisher","first-page":"1924","DOI":"10.1167\/iovs.07-1425","volume":"49","year":"2008","journal-title":"Investigative Ophthalmology & Visual Science","ISSN":"https:\/\/id.crossref.org\/issn\/0020-9988","issn-type":"print"},{"key":"6_31217598","doi-asserted-by":"crossref","first-page":"S162","DOI":"10.1016\/j.survophthal.2007.08.012","volume":"52","year":"2007","journal-title":"Survey of ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/0039-6257","issn-type":"print"},{"issue":"6","key":"7_17962236","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1177\/1073858403253460","volume":"9","author":"Neufeld","year":"2003","journal-title":"The Neuroscientist","ISSN":"https:\/\/id.crossref.org\/issn\/1073-8584","issn-type":"print"},{"issue":"2","key":"8_16067559","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1442-9071.1995.tb00135.x","volume":"23","author":"Quigley","year":"1995","journal-title":"Australian and New Zealand journal of ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/0814-9763","issn-type":"print"},{"issue":"7","key":"9_30105270","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1083\/jcb.200706181","volume":"179","year":"2007","journal-title":"The Journal of Cell Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9525","issn-type":"print"},{"issue":"1","key":"10_17357030","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1076\/ocii.10.1.27.10328","volume":"10","author":"Chen","year":"2002","journal-title":"Ocular immunology and inflammation","ISSN":"https:\/\/id.crossref.org\/issn\/0927-3948","issn-type":"print"},{"issue":"2","key":"11_28007341","doi-asserted-by":"publisher","first-page":"278","DOI":"10.3129\/can j ophthalmol.i07-036","volume":"42","author":"Nickells","year":"2007","journal-title":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","ISSN":"https:\/\/id.crossref.org\/issn\/0008-4182","issn-type":"print"},{"key":"12_31578883","first-page":"769","volume":"2","year":"1996","journal-title":"THE GLAUCOMAS"},{"issue":"3","key":"13_21810174","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.clinbiochem.2005.11.001","volume":"39","author":"Fan","year":"2006","journal-title":"Clinical biochemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0009-9120","issn-type":"print"},{"issue":"5300","key":"14_16675134","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1126\/science.275.5300.668","volume":"275","author":"Stone","year":"1997","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"4","key":"15_17175466","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/S1350-9462(02)00010-1","volume":"21","author":"Tamm","year":"2002","journal-title":"Progress in retinal and eye research","ISSN":"https:\/\/id.crossref.org\/issn\/1350-9462","issn-type":"print"},{"issue":"11","key":"16_18176768","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1093\/hmg\/ddh128","volume":"13","year":"2004","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"7","key":"17_10397357","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1001\/archopht.118.7.974","volume":"118","author":"Johnson","year":"2000","journal-title":"Archives of Ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/0003-9950","issn-type":"print"},{"issue":"6","key":"18_23679396","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1093\/hmg\/ddm001","volume":"16","year":"2007","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"6","key":"19_22106779","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1016\/j.exer.2005.11.002","volume":"82","author":"Gobeil","year":"2006","journal-title":"Experimental eye research","ISSN":"https:\/\/id.crossref.org\/issn\/0014-4835","issn-type":"print"},{"issue":"2","key":"20_11019722","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1093\/hmg\/10.2.117","volume":"10","author":"Jacobson","year":"2001","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"5557","key":"21_16906960","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1126\/science.1066901","volume":"295","author":"Rezaie","year":"2002","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"5","key":"22_17887656","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1016\/S0002-9394(03)00577-4","volume":"136","author":"Alward","year":"2003","journal-title":"American journal of ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9394","issn-type":"print"},{"issue":"7","key":"23_18951068","doi-asserted-by":"publisher","first-page":"2404","DOI":"10.1167\/iovs.04-1243","volume":"46","author":"Rezaie","year":"2005","journal-title":"Investigative Ophthalmology & Visual Science","ISSN":"https:\/\/id.crossref.org\/issn\/0020-9988","issn-type":"print"},{"issue":"1","key":"24_18579023","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.ygeno.2004.10.011","volume":"85","author":"Rezaie","year":"2005","journal-title":"Genomics","ISSN":"https:\/\/id.crossref.org\/issn\/0888-7543","issn-type":"print"},{"issue":"4","key":"25_18009501","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/S0896-1549(03)00061-0","volume":"16","author":"Sarfarazi","year":"2003","journal-title":"Ophthalmology clinics of North America","ISSN":"https:\/\/id.crossref.org\/issn\/0896-1549","issn-type":"print"},{"issue":"10","key":"26_5915909","doi-asserted-by":"publisher","first-page":"5815","DOI":"10.1074\/jbc.273.10.5815","volume":"273","author":"Chen","year":"1998","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"6","key":"27_18715844","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1093\/hmg\/ddi068","volume":"14","year":"2005","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"6","key":"30_22129486","doi-asserted-by":"publisher","first-page":"2542","DOI":"10.1167\/iovs.05-1476","volume":"47","author":"Hauser","year":"2006","journal-title":"Investigative Ophthalmology & Visual Science","ISSN":"https:\/\/id.crossref.org\/issn\/0020-9988","issn-type":"print"},{"issue":"2","key":"31_22442332","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.ajo.2006.02.041","volume":"142","author":"Hewitt","year":"2006","journal-title":"American journal of ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9394","issn-type":"print"},{"issue":"1","key":"32_30205734","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1167\/iovs.07-0500","volume":"49","author":"Pasutto","year":"2008","journal-title":"Investigative Ophthalmology & Visual Science","ISSN":"https:\/\/id.crossref.org\/issn\/0020-9988","issn-type":"print"},{"issue":"3","key":"33_23712738","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1001\/archopht.125.3.434-b","volume":"125","author":"Fingert","year":"2007","journal-title":"Archives of Ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/0003-9950","issn-type":"print"},{"key":"34_28861565","first-page":"724","volume":"13","author":"Weisschuh","year":"2007","journal-title":"Molecular vision [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1090-0535","issn-type":"print"},{"key":"35_29784218","first-page":"1912","volume":"13","author":"Miyazawa","year":"2007","journal-title":"Molecular vision [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1090-0535","issn-type":"print"},{"issue":"6","key":"36_18370789","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1016\/j.ygeno.2003.12.019","volume":"83","author":"Mao","year":"2004","journal-title":"Genomics","ISSN":"https:\/\/id.crossref.org\/issn\/0888-7543","issn-type":"print"},{"issue":"3","key":"37_9214743","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1006\/jmbi.1990.9999","volume":"215","author":"Altschul","year":"1990","journal-title":"Journal of molecular biology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2836","issn-type":"print"},{"issue":"6","key":"38_18561914","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.1128\/EC.3.6.1619-1626.2004","volume":"3","author":"Bernstein","year":"2004","journal-title":"Eukaryotic Cell","ISSN":"https:\/\/id.crossref.org\/issn\/1535-9778","issn-type":"print"},{"key":"39_31549043","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1038\/nature00769","volume":"417","year":"2002","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"35","key":"40_19687246","doi-asserted-by":"publisher","first-page":"12792","DOI":"10.1073\/pnas.0403929101","volume":"101","year":"2004","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"41_31578884","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.cell.2007.10.036","volume":"131","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"3","key":"42_21624188","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1167\/iovs.05-0830","volume":"47","author":"Stasi","year":"2006","journal-title":"Investigative Ophthalmology & Visual Science","ISSN":"https:\/\/id.crossref.org\/issn\/0020-9988","issn-type":"print"},{"issue":"3","key":"43_22312997","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.exer.2006.03.002","volume":"83","author":"Kuehn","year":"2006","journal-title":"Experimental eye research","ISSN":"https:\/\/id.crossref.org\/issn\/0014-4835","issn-type":"print"},{"issue":"7","key":"44_11067127","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1242\/dev.128.7.1175","volume":"128","author":"Udvadia","year":"2001","journal-title":"Development","ISSN":"https:\/\/id.crossref.org\/issn\/0950-1991","issn-type":"print"},{"issue":"1","key":"45_6484751","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1146\/annurev.genet.33.1.261","volume":"33","author":"Venema","year":"1999","journal-title":"Annual review of genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4197","issn-type":"print"},{"issue":"19","key":"46_21741894","doi-asserted-by":"publisher","first-page":"13309","DOI":"10.1074\/jbc.M601892200","volume":"281","year":"2006","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"7","key":"47_28930920","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1038\/nrm2184","volume":"8","author":"Boisvert","year":"2007","journal-title":"Nature reviews. Molecular cell biology","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0072","issn-type":"print"},{"issue":"23","key":"48_19731093","doi-asserted-by":"publisher","first-page":"2900","DOI":"10.1101\/gad.1366405","volume":"19","author":"Chen","year":"2005","journal-title":"Genes & Development","ISSN":"https:\/\/id.crossref.org\/issn\/0890-9369","issn-type":"print"},{"issue":"18","key":"49_19408988","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.1101\/gad.1339905","volume":"19","year":"2005","journal-title":"Genes & Development","ISSN":"https:\/\/id.crossref.org\/issn\/0890-9369","issn-type":"print"},{"issue":"23","key":"50_17369971","doi-asserted-by":"publisher","first-page":"2023","DOI":"10.1016\/S0960-9822(02)01319-2","volume":"12","author":"Langheinrich","year":"2002","journal-title":"Current biology : CB","ISSN":"https:\/\/id.crossref.org\/issn\/0960-9822","issn-type":"print"},{"issue":"1","key":"51_11475689","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0960-9822(01)00650-9","volume":"12","author":"Andersen","year":"2002","journal-title":"Current biology : CB","ISSN":"https:\/\/id.crossref.org\/issn\/0960-9822","issn-type":"print"},{"issue":"3","key":"52_10426299","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1083\/jcb.150.3.433","volume":"150","author":"Dundr","year":"2000","journal-title":"The Journal of Cell Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9525","issn-type":"print"},{"issue":"2","key":"53_19689428","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1073\/pnas.0406252102","volume":"102","year":"2005","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"1","key":"54_11462116","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1093\/hmg\/11.1.87","volume":"11","author":"Chakarova","year":"2002","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"2","key":"55_18465225","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.yexcr.2004.07.029","volume":"300","author":"Maita","year":"2004","journal-title":"Experimental cell research","ISSN":"https:\/\/id.crossref.org\/issn\/0014-4827","issn-type":"print"},{"issue":"15","key":"56_11248646","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.1093\/hmg\/10.15.1555","volume":"10","author":"McKie","year":"2001","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"2","key":"57_11311121","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/S1097-2765(01)00305-7","volume":"8","author":"Vithana","year":"2001","journal-title":"Molecular cell","ISSN":"https:\/\/id.crossref.org\/issn\/1097-2765","issn-type":"print"},{"key":"58_31578885","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1182\/blood-2006-07-038372","volume":"109","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/0006-4971","issn-type":"print"},{"issue":"24","key":"59_17345954","doi-asserted-by":"publisher","first-page":"8457","DOI":"10.1128\/MCB.22.24.8457-8466.2002","volume":"22","author":"Wang","year":"2002","journal-title":"Molecular and Cellular Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0270-7306","issn-type":"print"},{"issue":"1","key":"60_6002764","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/ng0598-32","volume":"19","author":"Heiss","year":"1998","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"8","key":"61_16878783","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1001\/archopht.1997.01100160201010","volume":"115","author":"Kerrigan","year":"1997","journal-title":"Archives of Ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/0003-9950","issn-type":"print"},{"key":"62_31578886","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1463-5224.2007.00564.x","volume":"10","year":"2007","journal-title":"Veterinary ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/1463-5216","issn-type":"print"},{"key":"63_17272485","first-page":"367","volume":"8","author":"Acharya","year":"2002","journal-title":"Molecular vision [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1090-0535","issn-type":"print"},{"issue":"7","key":"64_17118123","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1136\/bjo.86.7.767","volume":"86","author":"Lin","year":"2002","journal-title":"British Journal of Ophthalmology","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1161","issn-type":"print"},{"issue":"9","key":"65_19388177","doi-asserted-by":"publisher","first-page":"e55","DOI":"10.1136\/jmg.2005.032458","volume":"42","author":"Dimasi","year":"2005","journal-title":"Journal of Medical Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2593","issn-type":"print"},{"issue":"4","key":"66_18119307","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1136\/jmg.2003.016089","volume":"41","author":"Ressiniotis","year":"2004","journal-title":"Journal of Medical Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2593","issn-type":"print"},{"key":"67_18574605","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0091-679X(04)77027-2","volume":"77","author":"Thisse","year":"2004","journal-title":"Methods in cell biology","ISSN":"https:\/\/id.crossref.org\/issn\/0091-679X","issn-type":"print"},{"key":"68_31578887","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nprot.2007.514","volume":"3","year":"2008","journal-title":"NAT PROTOC"},{"issue":"1","key":"69_10821953","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1006\/abio.1999.4085","volume":"270","author":"Winer","year":"1999","journal-title":"Analytical biochemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0003-2697","issn-type":"print"},{"issue":"11","key":"70_29805523","doi-asserted-by":"publisher","first-page":"3088","DOI":"10.1002\/dvdy.21343","volume":"236","author":"Kwan","year":"2007","journal-title":"Developmental dynamics : an official publication of the American Association of Anatomists","ISSN":"https:\/\/id.crossref.org\/issn\/1058-8388","issn-type":"print"},{"key":"71_19190301","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/1471-213X-5-12","volume":"5","author":"Soules","year":"2005","journal-title":"BMC developmental biology [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-213X","issn-type":"print"},{"issue":"4","key":"72_22990482","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1111\/j.1747-0285.2006.00439.x","volume":"68","author":"Murphey","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1747-0277","issn-type":"print"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/hmg\/article\/17\/16\/2474\/2527328\/The-Primary-openangle-glaucoma-gene-WDR36","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T03:23:13Z","timestamp":1631244193000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddn147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,7]]},"references-count":69,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2008,5,7]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddn147","relation":{},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,7]]}}}