{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:17:53Z","timestamp":1791253073292,"version":"4.1.0"},"reference-count":64,"publisher":"Oxford University Press (OUP)","issue":"R2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Molecular Genetics"],"published-print":{"date-parts":[[2009,10,15]]},"DOI":"10.1093\/hmg\/ddp303","type":"journal-article","created":{"date-parts":[[2009,10,6]],"date-time":"2009-10-06T16:12:33Z","timestamp":1254845553000},"page":"R156-R162","source":"Crossref","is-referenced-by-count":297,"title":["Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis"],"prefix":"10.1093","volume":"18","author":[{"given":"G. S.","family":"Pesiridis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. M.-Y.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Q.","family":"Trojanowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,10,6]]},"reference":[{"issue":"1","key":"1_30043574","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1136\/jnnp.2006.104828","volume":"79","author":"Logroscino","year":"2008","journal-title":"Journal of Neurology, Neurosurgery &amp; Psychiatry","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3050","issn-type":"print"},{"issue":"5796","key":"2_22758976","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1126\/science.1134108","volume":"314","author":"Neumann","year":"2006","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"5","key":"3_30997639","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1001\/archneur.65.5.636","volume":"65","author":"Geser","year":"2008","journal-title":"Archives of Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0003-9942","issn-type":"print"},{"issue":"1","key":"5_32672360","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s00401-008-0460-5","volume":"117","author":"Mackenzie","year":"2009","journal-title":"Acta neuropathologica","ISSN":"https:\/\/id.crossref.org\/issn\/0001-6322","issn-type":"print"},{"issue":"4","key":"6_30116642","doi-asserted-by":"publisher","first-page":"S44","DOI":"10.1097\/WAD.0b013e31815c3486","volume":"21","author":"Mackenzie","year":"2007","journal-title":"Alzheimer disease and associated disorders","ISSN":"https:\/\/id.crossref.org\/issn\/0893-0341","issn-type":"print"},{"issue":"2","key":"7_33802786","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1001\/archneurol.2008.558","volume":"66","author":"Geser","year":"2009","journal-title":"Archives of Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0003-9942","issn-type":"print"},{"issue":"1","key":"8_29747480","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s00401-007-0226-5","volume":"114","author":"Kwong","year":"2007","journal-title":"Acta neuropathologica","ISSN":"https:\/\/id.crossref.org\/issn\/0001-6322","issn-type":"print"},{"issue":"1","key":"9_34493061","doi-asserted-by":"publisher","first-page":"232","DOI":"10.3390\/ijms10010232","volume":"10","author":"Neumann","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1422-0067","issn-type":"print"},{"issue":"3","key":"10_22983587","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1016\/j.bbrc.2006.10.093","volume":"351","author":"Arai","year":"2006","journal-title":"Biochemical and biophysical research communications","ISSN":"https:\/\/id.crossref.org\/issn\/0006-291X","issn-type":"print"},{"issue":"1","key":"11_28719276","doi-asserted-by":"publisher","first-page":"227","DOI":"10.2353\/ajpath.2007.070182","volume":"171","year":"2007","journal-title":"American Journal Of Pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9440","issn-type":"print"},{"issue":"12","key":"12_32677061","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1097\/NEN.0b013e31818e8951","volume":"67","author":"Schwab","year":"2008","journal-title":"Journal of neuropathology and experimental neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3069","issn-type":"print"},{"issue":"6","key":"13_31246501","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1097\/NEN.0b013e31817713b5","volume":"67","author":"Uryu","year":"2008","journal-title":"Journal of neuropathology and experimental neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3069","issn-type":"print"},{"issue":"5","key":"14_28502071","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1002\/ana.21154","volume":"61","author":"Amador-Ortiz","year":"2007","journal-title":"Annals of neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0364-5134","issn-type":"print"},{"issue":"6415","key":"15_10162536","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1038\/362059a0","volume":"362","author":"Rosen","year":"1993","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"3","key":"16_34544774","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1007\/s11910-009-0030-9","volume":"9","author":"Valdmanis","year":"2009","journal-title":"Current neurology and neuroscience reports","ISSN":"https:\/\/id.crossref.org\/issn\/1528-4042","issn-type":"print"},{"issue":"6","key":"17_34414189","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1016\/j.cell.2009.03.006","volume":"136","author":"Lagier-Tourenne","year":"2009","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"39","key":"18_19550383","doi-asserted-by":"publisher","first-page":"36337","DOI":"10.1074\/jbc.M104236200","volume":"276","year":"2001","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"1","key":"19_17949711","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/S0888-7543(03)00214-3","volume":"83","author":"Wang","year":"2004","journal-title":"Genomics","ISSN":"https:\/\/id.crossref.org\/issn\/0888-7543","issn-type":"print"},{"issue":"6430","key":"20_10261006","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1038\/363640a0","volume":"363","author":"Crozat","year":"1993","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"15","key":"21_5703294","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1242\/jcs.110.15.1741","volume":"110","author":"Zinszner","year":"1997","journal-title":"Journal of Cell Science","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9533","issn-type":"print"},{"issue":"2","key":"22_9689263","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1083\/jcb.116.2.257","volume":"116","author":"Matunis","year":"1992","journal-title":"The Journal of Cell Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9525","issn-type":"print"},{"issue":"1","key":"23_14418740","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1146\/annurev.bi.62.070193.001445","volume":"62","author":"Dreyfuss","year":"1993","journal-title":"Annual review of biochemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4154","issn-type":"print"},{"issue":"10","key":"24_17632159","doi-asserted-by":"publisher","first-page":"1653","DOI":"10.1016\/S0006-2952(03)00118-7","volume":"65","author":"Glisovic","year":"2003","journal-title":"Biochemical pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0006-2952","issn-type":"print"},{"key":"25_19155788","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1742-4690-2-8","volume":"2","author":"Kress","year":"2005","ISSN":"https:\/\/id.crossref.org\/issn\/1742-4690","issn-type":"print"},{"issue":"9","key":"26_22578605","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1038\/nsmb1135","volume":"13","author":"Listerman","year":"2006","journal-title":"Nature structural &amp; molecular biology","ISSN":"https:\/\/id.crossref.org\/issn\/1545-9993","issn-type":"print"},{"issue":"5","key":"27_34546197","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1038\/ni.1722","volume":"10","author":"Noguchi","year":"2009","journal-title":"Nature immunology","ISSN":"https:\/\/id.crossref.org\/issn\/1529-2908","issn-type":"print"},{"issue":"6","key":"28_15870541","doi-asserted-by":"crossref","first-page":"3584","DOI":"10.1128\/JVI.69.6.3584-3596.1995","volume":"69","author":"Ou","year":"1995","journal-title":"Journal of Virology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-538X","issn-type":"print"},{"issue":"2","key":"29_22349912","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1016\/j.ydbio.2006.04.443","volume":"295","author":"Acharya","year":"2006","journal-title":"Developmental biology","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1606","issn-type":"print"},{"issue":"50","key":"30_29613996","doi-asserted-by":"publisher","first-page":"36143","DOI":"10.1074\/jbc.M705811200","volume":"282","year":"2007","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"6","key":"31_18221916","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1086\/420978","volume":"74","author":"Buratti","year":"2004","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"45","key":"32_19576894","doi-asserted-by":"publisher","first-page":"37572","DOI":"10.1074\/jbc.M505557200","volume":"280","year":"2005","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"2","key":"33_9703431","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/0092-8674(92)90477-T","volume":"68","author":"Mayeda","year":"1992","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"9","key":"35_31788805","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1001\/archneur.65.9.1185","volume":"65","author":"Kuhnlein","year":"2008","journal-title":"Archives of Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0003-9942","issn-type":"print"},{"issue":"2","key":"36_32200469","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1136\/jmg.2008.062463","volume":"46","year":"2009","journal-title":"Journal of Medical Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2593","issn-type":"print"},{"issue":"5870","key":"37_30523683","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.1126\/science.1154584","volume":"319","year":"2008","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"5","key":"38_30928756","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S1474-4422(08)70071-1","volume":"7","author":"Van Deerlin","year":"2008","journal-title":"Lancet. Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/1474-4422","issn-type":"print"},{"issue":"5","key":"39_30990600","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1038\/ng.132","volume":"40","author":"Kabashi","year":"2008","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"4","key":"40_30986750","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1002\/ana.21392","volume":"63","author":"Yokoseki","year":"2008","journal-title":"Annals of neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0364-5134","issn-type":"print"},{"issue":"9","key":"41_31992647","doi-asserted-by":"publisher","first-page":"e1000193","DOI":"10.1371\/journal.pgen.1000193","volume":"4","author":"Rutherford","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1553-7390","issn-type":"print"},{"issue":"4","key":"42_34100039","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1002\/humu.20950","volume":"30","author":"Corrado","year":"2009","journal-title":"Human mutation","ISSN":"https:\/\/id.crossref.org\/issn\/1059-7794","issn-type":"print"},{"issue":"2","key":"43_33802813","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1001\/archneurol.2008.568","volume":"66","author":"Kabashi","year":"2009","journal-title":"Archives of Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0003-9942","issn-type":"print"},{"issue":"6","key":"44_31291313","doi-asserted-by":"publisher","first-page":"e2450","DOI":"10.1371\/journal.pone.0002450","volume":"3","author":"Guerreiro","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"6","key":"45_34139303","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1111\/j.1468-1331.2009.02574.x","volume":"16","author":"Del Bo","year":"2009","journal-title":"European journal of neurology : the official journal of the European Federation of Neurological Societies","ISSN":"https:\/\/id.crossref.org\/issn\/1351-5101","issn-type":"print"},{"key":"46_35695879","first-page":"1329","volume":"30","year":"2007","journal-title":"Neurobiology of aging","ISSN":"https:\/\/id.crossref.org\/issn\/0197-4580","issn-type":"print"},{"issue":"4","key":"47_34546617","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1002\/ana.21612","volume":"65","author":"Benajiba","year":"2009","journal-title":"Annals of neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0364-5134","issn-type":"print"},{"issue":"11","key":"48_15545351","doi-asserted-by":"publisher","first-page":"1996","DOI":"10.1093\/nar\/22.11.1996","volume":"22","author":"Biamonti","year":"1994","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"2","key":"49_34318487","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.bbrc.2009.03.038","volume":"382","author":"Kametani","year":"2009","journal-title":"Biochemical and biophysical research communications","ISSN":"https:\/\/id.crossref.org\/issn\/0006-291X","issn-type":"print"},{"issue":"10","key":"50_19688776","doi-asserted-by":"publisher","first-page":"3605","DOI":"10.1073\/pnas.0409889102","volume":"102","year":"2005","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"22","key":"51_15656983","doi-asserted-by":"crossref","first-page":"5483","DOI":"10.1002\/j.1460-2075.1994.tb06883.x","volume":"13","author":"Mayeda","year":"1994","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"},{"issue":"3","key":"52_16262128","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1006\/jmbi.1996.0324","volume":"259","author":"Cartegni","year":"1996","journal-title":"Journal of molecular biology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2836","issn-type":"print"},{"issue":"3","key":"53_15854084","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1083\/jcb.129.3.551","volume":"129","author":"Siomi","year":"1995","journal-title":"The Journal of Cell Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9525","issn-type":"print"},{"issue":"7","key":"54_6048561","doi-asserted-by":"crossref","first-page":"4141","DOI":"10.1128\/MCB.18.7.4141","volume":"18","author":"Siomi","year":"1998","journal-title":"Molecular and Cellular Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0270-7306","issn-type":"print"},{"issue":"2","key":"55_15892200","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1242\/jcs.108.2.545","volume":"108","author":"Weighardt","year":"1995","journal-title":"Journal of Cell Science","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9533","issn-type":"print"},{"issue":"1","key":"57_31248922","doi-asserted-by":"publisher","first-page":"182","DOI":"10.2353\/ajpath.2008.080003","volume":"173","year":"2008","journal-title":"American Journal Of Pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9440","issn-type":"print"},{"issue":"2","key":"58_33515096","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1007\/s00401-008-0477-9","volume":"117","author":"Neumann","year":"2009","journal-title":"Acta neuropathologica","ISSN":"https:\/\/id.crossref.org\/issn\/0001-6322","issn-type":"print"},{"issue":"19","key":"59_31613045","doi-asserted-by":"publisher","first-page":"2899","DOI":"10.1016\/j.febslet.2008.07.027","volume":"582","author":"Inukai","year":"2008","journal-title":"FEBS Letters","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3468","issn-type":"print"},{"key":"60_28306076","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/0022-510X(94)90191-0","volume":"124","year":"1994","journal-title":"Journal of the neurological sciences","ISSN":"https:\/\/id.crossref.org\/issn\/0022-510X","issn-type":"print"},{"issue":"5","key":"61_10663737","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1080\/146608200300079536","volume":"1","author":"Brooks","year":"2000","journal-title":"Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases","ISSN":"https:\/\/id.crossref.org\/issn\/1466-0822","issn-type":"print"},{"issue":"5","key":"62_28488036","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1007\/s00401-007-0206-9","volume":"113","author":"Tan","year":"2007","journal-title":"Acta neuropathologica","ISSN":"https:\/\/id.crossref.org\/issn\/0001-6322","issn-type":"print"},{"issue":"15","key":"63_31310027","doi-asserted-by":"publisher","first-page":"2252","DOI":"10.1016\/j.febslet.2008.05.024","volume":"582","author":"Winton","year":"2008","journal-title":"FEBS Letters","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3468","issn-type":"print"},{"issue":"2","key":"64_6411444","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1093\/hmg\/9.2.259","volume":"9","author":"Lorson","year":"2000","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"2","key":"65_23107466","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1093\/nar\/gkl1050","volume":"35","year":"2007","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"4","key":"66_34098953","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1038\/mt.2009.3","volume":"17","author":"Tatom","year":"2009","journal-title":"Molecular therapy : the journal of the American Society of Gene Therapy","ISSN":"https:\/\/id.crossref.org\/issn\/1525-0016","issn-type":"print"},{"issue":"10","key":"68_34662624","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1016\/j.febslet.2009.04.019","volume":"583","author":"Feiguin","year":"2009","journal-title":"FEBS Letters","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3468","issn-type":"print"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/18\/R2\/R156\/1651692\/ddp303.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T21:58:20Z","timestamp":1633989500000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddp303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,6]]},"references-count":64,"journal-issue":{"issue":"R2","published-online":{"date-parts":[[2009,10,6]]},"published-print":{"date-parts":[[2009,10,15]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddp303","relation":{},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,6]]}}}