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Biol. Chem."},{"key":"key\n\t\t\t\t20170522135943_DDP555C66","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/ng1747","article-title":"Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets","volume":"38","author":"Gandhi","year":"2006","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522135943_DDP555C67","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nmeth.1283","article-title":"Cost-effective strategies for completing the interactome","volume":"6","author":"Schwartz","year":"2009","journal-title":"Nat. Methods"},{"key":"key\n\t\t\t\t20170522135943_DDP555C68","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1093\/genetics\/118.3.461","article-title":"A stable genomic source of P element transposase in Drosophila melanogaster","volume":"118","author":"Robertson","year":"1988","journal-title":"Genetics"},{"key":"key\n\t\t\t\t20170522135943_DDP555C69","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/hmg\/ddi032","article-title":"Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis","volume":"14","author":"Sang","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522135943_DDP555C70","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/nature05954","article-title":"A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila","volume":"448","author":"Dietzl","year":"2007","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522135943_DDP555C71","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.bbalip.2009.01.007","article-title":"Emerging new paradigms for ABCG transporters","volume":"1791","author":"Tarr","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"key\n\t\t\t\t20170522135943_DDP555C72","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1080\/01677060802309629","article-title":"The white gene of Drosophila melanogaster encodes a protein with a role in courtship behavior","volume":"22","author":"Anaka","year":"2008","journal-title":"J. Neurogenet."},{"key":"key\n\t\t\t\t20170522135943_DDP555C73","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1139\/gen-42-6-1183","article-title":"A genetic and molecular characterization of the garnet gene of Drosophila melanogaster","volume":"42","author":"Lloyd","year":"1999","journal-title":"Genome"},{"key":"key\n\t\t\t\t20170522135943_DDP555C74","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1017\/S0016672309990152","article-title":"Targeted gain-of-function screening in Drosophila using GAL4-UAS and random transposon insertions","volume":"91","author":"Zhong","year":"2009","journal-title":"Genet. Res."},{"key":"key\n\t\t\t\t20170522135943_DDP555C75","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0012-1606(70)90098-9","article-title":"Ultrastructure of developing melanosomes in C57 black and pallid mice","volume":"23","author":"Theriault","year":"1970","journal-title":"Dev. Biol."},{"key":"key\n\t\t\t\t20170522135943_DDP555C76","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1046\/j.1523-1747.2002.19535.x","article-title":"Melanosome morphologies in murine models of Hermansky\u2013Pudlak syndrome reflect blocks in organelle development","volume":"119","author":"Nguyen","year":"2002","journal-title":"J. Invest. Dermatol."},{"key":"key\n\t\t\t\t20170522135943_DDP555C77","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1182\/blood-2004-04-1538","article-title":"Reduced pigmentation (rp), a mouse model of Hermansky\u2013Pudlak syndrome, encodes a novel component of the BLOC-1 complex","volume":"104","author":"Gwynn","year":"2004","journal-title":"Blood"},{"key":"key\n\t\t\t\t20170522135943_DDP555C78","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.neuron.2008.12.029","article-title":"Snapin facilitates the synchronization of synaptic vesicle fusion","volume":"61","author":"Pan","year":"2009","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522135943_DDP555C79","doi-asserted-by":"crossref","first-page":"10466","DOI":"10.1523\/JNEUROSCI.3001-04.2004","article-title":"Increased expression of the Drosophila vesicular glutamate transporter leads to excess glutamate release and a compensatory decrease in quantal content","volume":"24","author":"Daniels","year":"2004","journal-title":"J. Neurosci."},{"key":"key\n\t\t\t\t20170522135943_DDP555C80","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/nn2019","article-title":"A glial amino-acid transporter controls synapse strength and courtship in Drosophila","volume":"11","author":"Grosjean","year":"2008","journal-title":"Nat. Neurosci."},{"key":"key\n\t\t\t\t20170522135943_DDP555C81","doi-asserted-by":"crossref","first-page":"5525","DOI":"10.1073\/pnas.92.12.5525","article-title":"Misexpression of the white (w) gene triggers male-male courtship in Drosophila","volume":"92","author":"Zhang","year":"1995","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522135943_DDP555C82","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1387\/ijdb.051986da","article-title":"Rab11 is required during Drosophila eye development","volume":"49","author":"Alone","year":"2005","journal-title":"Int. J. Dev. Biol."},{"key":"key\n\t\t\t\t20170522135943_DDP555C83","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s10545-008-1014-7","article-title":"A data-mining approach to rank candidate protein-binding partners\u2014The case of biogenesis of lysosome-related organelles complex-1 (BLOC-1)","volume":"32","author":"Rodriguez-Fernandez","year":"2009","journal-title":"J. Inherit. Metab. Dis."},{"key":"key\n\t\t\t\t20170522135943_DDP555C84","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/sj.mp.4001880","article-title":"Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia","volume":"12","author":"Camargo","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"key\n\t\t\t\t20170522135943_DDP555C85","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1083\/jcb.200907122","article-title":"AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis","volume":"187","author":"Delevoye","year":"2009","journal-title":"J. Cell Biol."},{"key":"key\n\t\t\t\t20170522135943_DDP555C86","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/j.1600-0854.2007.00568.x","article-title":"Multiple roles of auxilin and hsc70 in clathrin-mediated endocytosis","volume":"8","author":"Eisenberg","year":"2007","journal-title":"Traffic"},{"key":"key\n\t\t\t\t20170522135943_DDP555C87","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0092-8674(00)80791-6","article-title":"A structural explanation for the binding of multiple ligands by the \u03b1-adaptin appendage domain","volume":"97","author":"Owen","year":"1999","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522135943_DDP555C88","doi-asserted-by":"crossref","first-page":"2991","DOI":"10.1091\/mbc.E06-12-1162","article-title":"Canonical interaction of cyclin G associated kinase with adaptor protein 1 regulates lysosomal enzyme sorting","volume":"18","author":"Kametaka","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"key\n\t\t\t\t20170522135943_DDP555C89","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s00406-008-0847-2","article-title":"Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia","volume":"259","author":"Martins-de-Souza","year":"2009","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"key\n\t\t\t\t20170522135943_DDP555C90","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.brainresrev.2008.04.006","article-title":"Rab GTPases and their roles in brain neurons and glia","volume":"58","author":"Ng","year":"2008","journal-title":"Brain Res. Rev."},{"key":"key\n\t\t\t\t20170522135943_DDP555C91","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0896-6273(01)00467-6","article-title":"Uncoating of clathrin-coated vesicles in presynaptic terminals: roles for Hsc70 and auxilin","volume":"32","author":"Morgan","year":"2001","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522135943_DDP555C92","doi-asserted-by":"crossref","first-page":"10881","DOI":"10.1093\/nar\/16.22.10881","article-title":"Multiple sequence alignment with hierarchical clustering","volume":"16","author":"Corpet","year":"1988","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170522135943_DDP555C93","doi-asserted-by":"crossref","first-page":"5859","DOI":"10.1093\/nar\/20.21.5859","article-title":"Position-independent germline transformation in Drosophila using a cuticle pigmentation gene as a selectable marker","volume":"20","author":"Patton","year":"1992","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170522135943_DDP555C94","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1242\/dev.118.2.401","article-title":"Targeted gene expression as a means of altering cell fates and generating dominant phenotypes","volume":"118","author":"Brand","year":"1993","journal-title":"Development"},{"key":"key\n\t\t\t\t20170522135943_DDP555C95","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1042\/BJ20051965","article-title":"Reinvestigation of the dysbindin subunit of BLOC-1 (biogenesis of lysosome-related organelles complex-1) as a dystrobrevin-binding protein","volume":"395","author":"Nazarian","year":"2006","journal-title":"Biochem. J."},{"key":"key\n\t\t\t\t20170522135943_DDP555C96","doi-asserted-by":"crossref","first-page":"28191","DOI":"10.1074\/jbc.M204011200","article-title":"BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet dense granules","volume":"277","author":"Falc\u00f3n-P\u00e9rez","year":"2002","journal-title":"J. Biol. 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