{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:21:17Z","timestamp":1792131677882,"version":"4.4.0"},"reference-count":79,"publisher":"Oxford University Press (OUP)","issue":"15","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,8,1]]},"DOI":"10.1093\/hmg\/dds163","type":"journal-article","created":{"date-parts":[[2012,4,27]],"date-time":"2012-04-27T21:26:26Z","timestamp":1335561986000},"page":"3333-3344","source":"Crossref","is-referenced-by-count":116,"title":["OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome"],"prefix":"10.1093","volume":"21","author":[{"given":"Na","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Callah C.","family":"West","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos A.","family":"Murga-Zamalloa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lou","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan M.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clark D.","family":"Wells","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert N.","family":"Weinreb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey B.","family":"Travers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemant","family":"Khanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,4,27]]},"reference":[{"key":"key\n\t\t\t\t20170522131826_DDS163C1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jpeds.2009.01.049","article-title":"Dent-2 disease: a mild variant of Lowe syndrome","volume":"155","year":"2009","journal-title":"J. Pediatr."},{"key":"key\n\t\t\t\t20170522131826_DDS163C2","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1086\/427887","article-title":"Dent Disease with mutations in OCRL1","volume":"76","year":"2005","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C3","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/nrneph.2009.124","article-title":"Inherited cerebrorenal syndromes","volume":"5","year":"2009","journal-title":"Nat. Rev. Nephrol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C4","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.bbrc.2008.02.067","article-title":"All known patient mutations in the ASH-RhoGAP domains of OCRL affect targeting and APPL1 binding","volume":"369","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"key\n\t\t\t\t20170522131826_DDS163C5","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1600-0854.2005.00311.x","article-title":"Structure and function of the Lowe syndrome protein OCRL1","volume":"6","year":"2005","journal-title":"Traffic"},{"key":"key\n\t\t\t\t20170522131826_DDS163C6","doi-asserted-by":"crossref","first-page":"13501","DOI":"10.1073\/pnas.0405664101","article-title":"The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin","volume":"101","year":"2004","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522131826_DDS163C7","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.1038\/sj.emboj.7601274","article-title":"Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases","volume":"25","year":"2006","journal-title":"EMBO J."},{"key":"key\n\t\t\t\t20170522131826_DDS163C8","doi-asserted-by":"crossref","first-page":"e24044","DOI":"10.1371\/journal.pone.0024044","article-title":"Lowe Syndrome protein OCRL1 supports maturation of polarized epithelial cells","volume":"6","year":"2011","journal-title":"PLoS ONE"},{"key":"key\n\t\t\t\t20170522131826_DDS163C9","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.devcel.2007.08.004","article-title":"A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway","volume":"13","year":"2007","journal-title":"Dev. Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C10","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1038\/emboj.2009.155","article-title":"A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism","volume":"28","year":"2009","journal-title":"EMBO J."},{"key":"key\n\t\t\t\t20170522131826_DDS163C11","doi-asserted-by":"crossref","first-page":"F335","DOI":"10.1152\/ajprenal.00453.2009","article-title":"OCRL1 function in renal epithelial membrane traffic","volume":"298","year":"2010","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C12","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1091\/mbc.E11-06-0489","article-title":"Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling","volume":"23","year":"2012","journal-title":"Mol. Biol. Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C13","doi-asserted-by":"crossref","first-page":"4853","DOI":"10.1073\/pnas.92.11.4853","article-title":"The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase","volume":"92","year":"1995","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522131826_DDS163C14","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1038\/ncb2279","article-title":"Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis","volume":"13","year":"2011","journal-title":"Nat. Cell Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C15","doi-asserted-by":"crossref","first-page":"9965","DOI":"10.1074\/jbc.M807442200","article-title":"Differential clathrin binding and subcellular localization of OCRL1 splice isoforms","volume":"284","year":"2009","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522131826_DDS163C16","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1091\/mbc.E05-02-0120","article-title":"Lowe syndrome protein OCRL1 interacts with clathrin and regulates protein trafficking between endosomes and the trans-Golgi network","volume":"16","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C17","first-page":"4970","article-title":"OCRL controls trafficking through early endosomes via PtdIns4,5P(2)-dependent regulation of endosomal actin","volume":"24","year":"2011","journal-title":"EMBO J."},{"key":"key\n\t\t\t\t20170522131826_DDS163C18","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1091\/mbc.E10-08-0730","article-title":"The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway","volume":"22","year":"2011","journal-title":"Mol. Biol. Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C19","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1073\/pnas.0914658107","article-title":"Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1","volume":"107","year":"2010","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522131826_DDS163C20","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1038\/emboj.2011.60","article-title":"A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1","volume":"30","year":"2011","journal-title":"EMBO J."},{"key":"key\n\t\t\t\t20170522131826_DDS163C21","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ymgme.2006.04.005","article-title":"The effect of missense mutations in the RhoGAP-homology domain on ocrl1 function","volume":"89","year":"2006","journal-title":"Mol. Genet. Metab."},{"key":"key\n\t\t\t\t20170522131826_DDS163C22","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1086\/344517","article-title":"The deficiency of PIP2 5-phosphatase in Lowe syndrome affects actin polymerization","volume":"71","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C23","doi-asserted-by":"crossref","first-page":"4478","DOI":"10.1093\/hmg\/ddp407","article-title":"Lowe syndrome patient fibroblasts display Ocrl1-specific cell migration defects that cannot be rescued by the homologous Inpp5b phosphatase","volume":"18","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C24","doi-asserted-by":"crossref","first-page":"13377","DOI":"10.1073\/pnas.0906944106","article-title":"Mouse Kif7\/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling","volume":"106","year":"2009","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522131826_DDS163C25","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.cell.2007.04.035","article-title":"HEF1-dependent Aurora A activation induces disassembly of the primary cilium","volume":"129","year":"2007","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C26","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1016\/j.cub.2005.09.012","article-title":"PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts","volume":"15","year":"2005","journal-title":"Curr. Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C27","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1038\/nm.2011","article-title":"Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis","volume":"15","year":"2009","journal-title":"Nat. Med."},{"key":"key\n\t\t\t\t20170522131826_DDS163C28","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1083\/jcb.200707181","article-title":"Cep164, a novel centriole appendage protein required for primary cilium formation","volume":"179","year":"2007","journal-title":"J. Cell Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C29","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/S0960-9822(03)00174-X","article-title":"Gamma-tubulin functions in the nucleation of a discrete subset of microtubules in the eukaryoticflagellum","volume":"13","year":"2003","journal-title":"Curr. Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C30","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1083\/jcb.104.2.289","article-title":"Microtubules containing acetylated alpha-tubulin in mammalian cells in culture","volume":"104","year":"1987","journal-title":"J. Cell Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C31","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/ncb0411-340","article-title":"Do cilia put brakes on the cell cycle?","volume":"13","year":"2011","journal-title":"Nat. Cell Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C32","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.devcel.2007.08.007","article-title":"Centrioles want to move out and make cilia","volume":"13","year":"2007","journal-title":"Dev. Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C33","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/nrm3085","article-title":"Ciliogenesis: building the cell's antenna","volume":"12","year":"2011","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C34","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1146\/annurev.physiol.67.040403.101353","article-title":"A physiological view of the primary cilium","volume":"67","year":"2005","journal-title":"Annu. Rev. Physiol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C35","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1146\/annurev.cellbio.19.111401.091318","article-title":"Intraflagellar transport","volume":"19","year":"2003","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C36","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1083\/jcb.200911095","article-title":"Intraflagellar transport molecules in ciliary and nonciliary cells of the retina","volume":"189","year":"2010","journal-title":"J. Cell Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C37","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1091\/mbc.E10-03-0269","article-title":"Soluble levels of cytosolic tubulin regulate ciliary length control","volume":"22","year":"2011","journal-title":"Mol. Biol. Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C38","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/ng2066","article-title":"Mutations in LCA5, encoding the ciliary protein lebercilin, cause Leber congenital amaurosis","volume":"39","year":"2007","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C39","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1056\/NEJMra1010172","article-title":"Ciliopathies","volume":"364","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"key\n\t\t\t\t20170522131826_DDS163C40","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.cell.2011.09.014","article-title":"Modeling human disease in humans: the ciliopathies","volume":"147","year":"2011","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C41","doi-asserted-by":"crossref","first-page":"20110","DOI":"10.1074\/jbc.M910119199","article-title":"The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase","volume":"275","year":"2000","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522131826_DDS163C42","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1038\/ng.423","article-title":"Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies","volume":"41","year":"2009","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C43","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/01.ijg.0000158850.07732.05","article-title":"Glaucoma with the oculocerebrorenal syndrome of Lowe","volume":"14","year":"2005","journal-title":"J. Glaucoma"},{"key":"key\n\t\t\t\t20170522131826_DDS163C44","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/BF00410985","article-title":"Cilia in the ciliary epithelium","volume":"213","year":"1980","journal-title":"Albrecht Von Graefes Arch. Klin. Exp. Ophthalmol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C45","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1083\/jcb.101.6.2085","article-title":"Monoclonal antibodies specific for an acetylated form of alpha-tubulin recognize the antigen in cilia and flagella from a variety of organisms","volume":"101","year":"1985","journal-title":"J. Cell Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C46","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/cm.970030207","article-title":"Cell motility and microtubules in cultured fibroblasts from patients with Kartagener syndrome","volume":"3","year":"1983","journal-title":"Cell Motil."},{"key":"key\n\t\t\t\t20170522131826_DDS163C47","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.cell.2007.03.053","article-title":"A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis","volume":"129","year":"2007","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C48","doi-asserted-by":"crossref","first-page":"3591","DOI":"10.1093\/hmg\/ddq275","article-title":"Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration","volume":"19","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C49","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.1073\/pnas.1018823108","article-title":"Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome","volume":"108","year":"2011","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522131826_DDS163C50","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1083\/jcb.200703047","article-title":"Functional dissection of Rab GTPases involved in primary cilium formation","volume":"178","year":"2007","journal-title":"J. Cell Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C51","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1042\/BJ20081673","article-title":"The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease","volume":"419","year":"2009","journal-title":"Biochem. J."},{"key":"key\n\t\t\t\t20170522131826_DDS163C52","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1093\/hmg\/ddq543","article-title":"TOPORS, implicated in retinal degeneration, is a cilia-centrosomal protein","volume":"20","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C53","doi-asserted-by":"crossref","first-page":"4330","DOI":"10.1093\/hmg\/ddq355","article-title":"The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development","volume":"19","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C54","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.cell.2006.03.002","article-title":"Nodal flow and the generation of left-right asymmetry","volume":"125","year":"2006","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C55","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/nrg2717","article-title":"Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait","volume":"11","year":"2010","journal-title":"Nat. Rev. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C56","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1146\/annurev.cellbio.042308.113337","article-title":"Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?","volume":"26","year":"2010","journal-title":"Annu. Rev. Cell. Dev. Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C57","doi-asserted-by":"crossref","first-page":"15523","DOI":"10.1073\/pnas.1002897107","article-title":"Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice","volume":"107","year":"2010","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522131826_DDS163C58","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/ng.662","article-title":"Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy","volume":"42","year":"2010","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C59","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1146\/annurev-physiol-012110-142228","article-title":"How the genetics of deafness illuminates auditory physiology","volume":"73","year":"2011","journal-title":"Annu. Rev. Physiol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C60","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/ng.366","article-title":"A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies","volume":"41","year":"2009","journal-title":"Nat. Genet."},{"issue":"Spec No. 2","key":"key\n\t\t\t\t20170522131826_DDS163C61","first-page":"R235","article-title":"Genetic basis of Joubert syndrome and related disorders of cerebellar development","volume":"14","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C62","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/nm.2380","article-title":"Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome","volume":"17","year":"2011","journal-title":"Nat. Med."},{"key":"key\n\t\t\t\t20170522131826_DDS163C63","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1074\/jbc.273.3.1574","article-title":"Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate","volume":"273","year":"1998","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522131826_DDS163C64","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1212\/WNL.0b013e3181fb3616","article-title":"Stroke treatment and prevention: five new things","volume":"75","year":"2010","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170522131826_DDS163C65","doi-asserted-by":"crossref","first-page":"28276","DOI":"10.1074\/jbc.M111.237560","article-title":"Accumulation of the Raf-1 kinase inhibitory protein (Rkip) is associated with Cep290-mediated photoreceptor degeneration in ciliopathies","volume":"286","year":"2011","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522131826_DDS163C66","article-title":"Lowe syndrome","year":"1993\u20132001","journal-title":"GeneReviews"},{"key":"key\n\t\t\t\t20170522131826_DDS163C67","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1038\/ng.427","article-title":"INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse","volume":"41","year":"2009","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C68","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1074\/mcp.M700569-MCP200","article-title":"Large scale screening for novel rab effectors reveals unexpected broad Rab binding specificity","volume":"7","year":"2008","journal-title":"Mol. Cell Proteomics"},{"key":"key\n\t\t\t\t20170522131826_DDS163C69","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1471-4159.2004.02463.x","article-title":"The interaction of Bex and OMP reveals a dimer of OMP with a short half-life","volume":"90","year":"2004","journal-title":"J. Neurochem."},{"key":"key\n\t\t\t\t20170522131826_DDS163C70","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1038\/nature08895","article-title":"Functional genomic screen for modulators of ciliogenesis and cilium length","volume":"464","year":"2010","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522131826_DDS163C71","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1172\/JCI2414","article-title":"Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice","volume":"101","year":"1998","journal-title":"J. Clin. Invest."},{"key":"key\n\t\t\t\t20170522131826_DDS163C72","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1095\/biolreprod66.5.1522","article-title":"Sertoli cell vacuolization and abnormal germ cell adhesion in mice deficient in an inositol polyphosphate 5-phosphatase","volume":"66","year":"2002","journal-title":"Biol. Reprod."},{"key":"key\n\t\t\t\t20170522131826_DDS163C73","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1681\/ASN.2010050565","article-title":"Mouse model for Lowe syndrome\/Dent Disease 2 renal tubulopathy","volume":"22","year":"2011","journal-title":"J. Am. Soc. Nephrol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C74","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1083\/jcb.200812084","article-title":"Intraflagellar transport particle size scales inversely with flagellar length: revisiting the balance-point length control model","volume":"187","year":"2009","journal-title":"J. Cell Biol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C75","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.devcel.2006.04.010","article-title":"More than just the postal service: novel roles for IFT proteins in signal transduction","volume":"10","year":"2006","journal-title":"Dev. Cell"},{"key":"key\n\t\t\t\t20170522131826_DDS163C76","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1093\/bioinformatics\/btl022","article-title":"A novel domain suggests a ciliary function for ASPM, a brain size determining gene","volume":"22","year":"2006","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t20170522131826_DDS163C77","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1093\/hmg\/ddr615","article-title":"The Lowe syndrome protein OCRL1 is involved in primary cilia assembly","volume":"21","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522131826_DDS163C78","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1472-6750-6-13","article-title":"Modification of the Creator recombination system for proteomics applications\u2014improved expression by addition of splice sites","volume":"6","year":"2006","journal-title":"BMC Biotechnol."},{"key":"key\n\t\t\t\t20170522131826_DDS163C79","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S1672-0229(10)60025-3","article-title":"A multifunctional lentiviral-based gene knockdown with concurrent rescue that controls for off-target effects of RNAi","volume":"8","year":"2010","journal-title":"Genomics Proteomics Bioinformatics"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T13:59:46Z","timestamp":1497967186000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/dds163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,27]]},"references-count":79,"journal-issue":{"issue":"15","published-online":{"date-parts":[[2012,4,27]]},"published-print":{"date-parts":[[2012,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/dds163","relation":{},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,27]]}}}