{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:12:12Z","timestamp":1791249132654,"version":"4.1.0"},"reference-count":51,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Molecular Genetics"],"published-print":{"date-parts":[[2013,3,15]]},"DOI":"10.1093\/hmg\/dds528","type":"journal-article","created":{"date-parts":[[2013,1,3]],"date-time":"2013-01-03T06:56:08Z","timestamp":1357196168000},"page":"1206-1217","source":"Crossref","is-referenced-by-count":19,"title":["Tcof1 acts as a modifier of Pax3 during enteric nervous system development and in the pathogenesis of colonic aganglionosis"],"prefix":"10.1093","volume":"22","author":[{"given":"A. J.","family":"Barlow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Dixon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Dixon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. A.","family":"Trainor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,1,2]]},"reference":[{"issue":"6","key":"1_28750083","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1038\/nrn2137","volume":"8","author":"Heanue","year":"2007","journal-title":"Nature reviews. Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/1471-003X","issn-type":"print"},{"issue":"1","key":"2_12528051","first-page":"31","volume":"30","author":"Le Douarin","year":"1973","journal-title":"Journal of embryology and experimental morphology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-0752","issn-type":"print"},{"issue":"1","key":"3_35674157","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.autneu.2009.09.001","volume":"151","author":"Laranjeira","year":"2009","journal-title":"Autonomic neuroscience : basic & clinical","ISSN":"https:\/\/id.crossref.org\/issn\/1566-0702","issn-type":"print"},{"issue":"1","key":"4_29780706","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1136\/jmg.2007.053959","volume":"45","year":"2008","journal-title":"Journal of Medical Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2593","issn-type":"print"},{"issue":"1","key":"5_22785002","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1097\/00001574-200201000-00013","volume":"18","author":"Belknap","year":"2002","journal-title":"Current opinion in gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0267-1379","issn-type":"print"},{"issue":"6","key":"6_10571950","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1097\/00008480-200012000-00017","volume":"12","author":"Parisi","year":"2000","journal-title":"Current opinion in pediatrics","ISSN":"https:\/\/id.crossref.org\/issn\/1040-8703","issn-type":"print"},{"issue":"1","key":"7_16695057","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/S0959-4388(97)80127-4","volume":"7","author":"Gershon","year":"1997","journal-title":"Current opinion in neurobiology","ISSN":"https:\/\/id.crossref.org\/issn\/0959-4388","issn-type":"print"},{"issue":"8","key":"8_33900143","doi-asserted-by":"publisher","first-page":"2694","DOI":"10.1073\/pnas.0809630105","volume":"106","year":"2009","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"1","key":"9_39146282","doi-asserted-by":"publisher","first-page":"e16181","DOI":"10.1371\/journal.pone.0016181","volume":"6","author":"Tang","year":"2011","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"45","key":"10_41681054","doi-asserted-by":"publisher","first-page":"4937","DOI":"10.3748\/wjg.v17.i45.4937","volume":"17","author":"Wallace","year":"2011","journal-title":"World journal of gastroenterology : WJG","ISSN":"https:\/\/id.crossref.org\/issn\/1007-9327","issn-type":"print"},{"issue":"4","key":"11_36616579","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1002\/humu.21211","volume":"31","author":"Pingault","year":"2010","journal-title":"Human mutation","ISSN":"https:\/\/id.crossref.org\/issn\/1059-7794","issn-type":"print"},{"issue":"2","key":"12_16054869","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1002\/ajmg.1320580205","volume":"58","author":"Baldwin","year":"1995","journal-title":"American journal of medical genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0148-7299","issn-type":"print"},{"issue":"3","key":"13_10164553","first-page":"455","volume":"52","author":"Hoth","year":"1993","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"6361","key":"14_9741895","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1038\/355635a0","volume":"355","author":"Tassabehji","year":"1992","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"8","key":"15_10514812","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1172\/JCI10828","volume":"106","author":"Lang","year":"2000","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"8","key":"16_17563120","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1093\/hmg\/ddg107","volume":"12","author":"Lang","year":"2003","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"10","key":"17_35856570","doi-asserted-by":"publisher","first-page":"1904","DOI":"10.1016\/j.jpedsurg.2008.11.055","volume":"44","author":"Leon","year":"2009","journal-title":"Journal of pediatric surgery","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3468","issn-type":"print"},{"issue":"8","key":"18_41512065","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1093\/hmg\/ddr611","volume":"21","year":"2012","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"2","key":"19_30413814","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1038\/nm1725","volume":"14","author":"Jones","year":"2008","journal-title":"Nature medicine","ISSN":"https:\/\/id.crossref.org\/issn\/1078-8956","issn-type":"print"},{"issue":"2","key":"20_16164310","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1038\/ng0296-130","volume":"12","year":"1996","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"36","key":"21_22546323","doi-asserted-by":"publisher","first-page":"13403","DOI":"10.1073\/pnas.0603730103","volume":"103","year":"2006","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"6","key":"22_16975637","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1101\/gad.969302","volume":"16","author":"Pani","year":"2002","journal-title":"Genes & Development","ISSN":"https:\/\/id.crossref.org\/issn\/0890-9369","issn-type":"print"},{"issue":"6461","key":"23_14683996","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1038\/367380a0","volume":"367","author":"Schuchardt","year":"1994","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"key":"24_23825001","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/jez.1401270206","volume":"127","year":"1954","journal-title":"The Journal of experimental zoology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-104X","issn-type":"print"},{"issue":"4","key":"25_9614355","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1016\/0092-8674(91)90071-6","volume":"67","author":"Epstein","year":"1991","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"2","key":"26_10107642","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1073\/pnas.90.2.532","volume":"90","author":"Epstein","year":"1993","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"24","key":"27_17316556","doi-asserted-by":"publisher","first-page":"3075","DOI":"10.1093\/hmg\/11.24.3075","volume":"11","author":"Paratore","year":"2002","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"1","key":"28_17582618","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/S0896-6273(03)00163-6","volume":"38","author":"Kim","year":"2003","journal-title":"Neuron","ISSN":"https:\/\/id.crossref.org\/issn\/0896-6273","issn-type":"print"},{"issue":"10","key":"29_21946099","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.1242\/dev.02375","volume":"133","year":"2006","journal-title":"Development","ISSN":"https:\/\/id.crossref.org\/issn\/0950-1991","issn-type":"print"},{"issue":"25","key":"30_17910948","doi-asserted-by":"publisher","first-page":"6387","DOI":"10.1242\/dev.00857","volume":"130","author":"Bondurand","year":"2003","journal-title":"Development","ISSN":"https:\/\/id.crossref.org\/issn\/0950-1991","issn-type":"print"},{"issue":"1","key":"31_16162606","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1242\/dev.122.1.349","volume":"122","author":"Durbec","year":"1996","journal-title":"Development","ISSN":"https:\/\/id.crossref.org\/issn\/0950-1991","issn-type":"print"},{"issue":"9-10","key":"32_31640225","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.mod.2008.07.003","volume":"125","author":"Morgan","year":"2008","journal-title":"Mechanisms of development","ISSN":"https:\/\/id.crossref.org\/issn\/0925-4773","issn-type":"print"},{"issue":"7","key":"33_16825607","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.2337\/diab.46.7.1189","volume":"46","author":"Phelan","year":"1997","journal-title":"Diabetes","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1797","issn-type":"print"},{"issue":"30","key":"34_30098683","doi-asserted-by":"publisher","first-page":"5831","DOI":"10.1016\/j.febslet.2007.11.056","volume":"581","author":"Underwood","year":"2007","journal-title":"FEBS Letters","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3468","issn-type":"print"},{"issue":"1","key":"35_18546179","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.ydbio.2004.09.014","volume":"277","author":"Maka","year":"2005","journal-title":"Developmental biology","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1606","issn-type":"print"},{"issue":"1","key":"36_22372848","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.ydbio.2006.03.031","volume":"295","author":"Stanchina","year":"2006","journal-title":"Developmental biology","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1606","issn-type":"print"},{"issue":"3","key":"37_37891803","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1016\/j.nbd.2010.08.006","volume":"40","author":"Wallace","year":"2010","journal-title":"Neurobiology of disease","ISSN":"https:\/\/id.crossref.org\/issn\/0969-9961","issn-type":"print"},{"issue":"7","key":"38_34711220","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1111\/j.1365-2982.2009.01309.x","volume":"21","author":"Wallace","year":"2009","journal-title":"Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society","ISSN":"https:\/\/id.crossref.org\/issn\/1350-1925","issn-type":"print"},{"issue":"9","key":"39_30738482","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.1242\/dev.017418","volume":"135","year":"2008","journal-title":"Development","ISSN":"https:\/\/id.crossref.org\/issn\/0950-1991","issn-type":"print"},{"issue":"2","key":"40_36500667","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.ydbio.2009.12.014","volume":"339","author":"Zhang","year":"2010","journal-title":"Developmental biology","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1606","issn-type":"print"},{"issue":"2","key":"41_36770980","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/j.ydbio.2010.02.036","volume":"341","author":"Stanchina","year":"2010","journal-title":"Developmental biology","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1606","issn-type":"print"},{"issue":"21","key":"42_32063659","doi-asserted-by":"publisher","first-page":"3555","DOI":"10.1242\/dev.022319","volume":"135","year":"2008","journal-title":"Development","ISSN":"https:\/\/id.crossref.org\/issn\/0950-1991","issn-type":"print"},{"issue":"21","key":"43_40944212","doi-asserted-by":"publisher","first-page":"4789","DOI":"10.1242\/dev.060053","volume":"138","author":"Lei","year":"2011","journal-title":"Development","ISSN":"https:\/\/id.crossref.org\/issn\/0950-1991","issn-type":"print"},{"issue":"2","key":"44_41770358","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/j.ydbio.2012.01.003","volume":"363","author":"Mundell","year":"2012","journal-title":"Developmental biology","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1606","issn-type":"print"},{"issue":"5","key":"45_23308473","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1002\/j.1460-2075.1991.tb08054.x","volume":"10","author":"Goulding","year":"1991","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"},{"issue":"2","key":"46_16686222","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1242\/dev.124.2.505","volume":"124","author":"Conway","year":"1997","journal-title":"Development","ISSN":"https:\/\/id.crossref.org\/issn\/0950-1991","issn-type":"print"},{"issue":"9","key":"47_6540483","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1242\/dev.127.9.1869","volume":"127","author":"Epstein","year":"2000","journal-title":"Development","ISSN":"https:\/\/id.crossref.org\/issn\/0950-1991","issn-type":"print"},{"issue":"2","key":"48_30711164","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/S0008-6363(00)00098-5","volume":"47","year":"2000","journal-title":"Cardiovascular Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-6363","issn-type":"print"},{"issue":"7028","key":"49_18698254","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1038\/nature03292","volume":"433","author":"Lang","year":"2005","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"6","key":"50_32549611","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1111\/j.1755-148X.2008.00514.x","volume":"21","author":"Kubic","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1755-1471","issn-type":"print"},{"issue":"10","key":"51_10385944","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.1093\/hmg\/9.10.1473","volume":"9","author":"Dixon","year":"2000","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/22\/6\/1206\/1569025\/dds528.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,5]],"date-time":"2022-02-05T03:29:02Z","timestamp":1644031742000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/dds528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,2]]},"references-count":51,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2013,2,21]]},"published-print":{"date-parts":[[2013,3,15]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/dds528","relation":{},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,2]]}}}