{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:52:45Z","timestamp":1791017565135,"version":"4.1.0"},"reference-count":64,"publisher":"Oxford University Press (OUP)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,7,15]]},"DOI":"10.1093\/hmg\/ddt130","type":"journal-article","created":{"date-parts":[[2013,3,23]],"date-time":"2013-03-23T01:50:24Z","timestamp":1364003424000},"page":"2811-2819","source":"Crossref","is-referenced-by-count":20,"title":["Distinct roles for Toll and autophagy pathways in double-stranded RNA toxicity in a Drosophila model of expanded repeat neurodegenerative diseases"],"prefix":"10.1093","volume":"22","author":[{"given":"Saumya E.","family":"Samaraweera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise V.","family":"O'Keefe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gareth R.","family":"Price","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deon J.","family":"Venter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert I.","family":"Richards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,3,21]]},"reference":[{"key":"key\n\t\t\t\t20170522153949_DDT130C1","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1093\/hmg\/10.20.2187","article-title":"Dynamic mutations: a decade of unstable expanded repeats in human genetic disease","volume":"10","author":"Richards","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C2","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/nrg2748","article-title":"Repeat expansion disease: progress and puzzles in disease pathogenesis","volume":"11","author":"La Spada","year":"2010","journal-title":"Nat. Rev. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C3","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1146\/annurev.neuro.29.051605.113042","article-title":"Trinucleotide repeat disorders","volume":"30","author":"Orr","year":"2007","journal-title":"Annu. Rev. Neurosci."},{"key":"key\n\t\t\t\t20170522153949_DDT130C4","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.ajhg.2009.09.019","article-title":"Spinocerebellar ataxia type 31 is associated with \"inserted\" penta-nucleotide repeats containing (TGGAA)n","volume":"85","author":"Sato","year":"2009","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C5","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ajhg.2011.05.015","article-title":"Expansion of intronic GGCCTG hexanucleotide repeat in NOP56 causes SCA36, a type of spinocerebellar ataxia accompanied by motor neuron involvement","volume":"89","author":"Kobayashi","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C6","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.neuron.2011.09.011","article-title":"Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS","volume":"72","author":"DeJesus-Hernandez","year":"2011","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522153949_DDT130C7","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.neuron.2011.09.010","article-title":"A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD","volume":"72","author":"Renton","year":"2011","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522153949_DDT130C8","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1038\/nature06909","article-title":"RNA toxicity is a component of ataxin-3 degeneration in Drosophila","volume":"453","author":"Li","year":"2008","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522153949_DDT130C9","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1093\/hmg\/ddi096","article-title":"The pathogenic agent in Drosophila models of \u2018polyglutamine\u2019 diseases","volume":"14","author":"McLeod","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C10","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1093\/hmg\/ddr177","article-title":"Perturbation of the Akt\/Gsk3-beta signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs","volume":"20","author":"van Eyk","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C11","doi-asserted-by":"crossref","first-page":"3757","DOI":"10.1093\/hmg\/ddr292","article-title":"Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases","volume":"20","author":"Lawlor","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C12","doi-asserted-by":"crossref","first-page":"e1001340","DOI":"10.1371\/journal.pgen.1001340","article-title":"Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy","volume":"7","author":"Yu","year":"2011","journal-title":"PLoS Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C13","doi-asserted-by":"crossref","first-page":"e38516","DOI":"10.1371\/journal.pone.0038516","article-title":"Ubiquitous expression of CUG or CAG trinucleotide repeat RNA causes common morphological defects in a Drosophila model of RNA-mediated pathology","volume":"7","author":"Lawlor","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170522153949_DDT130C14","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1093\/hmg\/10.19.2165","article-title":"Muscleblind localizes to nuclear foci of aberrant RNA in myotonic dystrophy types 1 and 2","volume":"10","author":"Mankodi","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C15","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1073\/pnas.1013343108","article-title":"Non-ATG-initiated translation directed by microsatellite expansions","volume":"108","author":"Zu","year":"2011","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522153949_DDT130C16","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1093\/hmg\/ddr487","article-title":"Comparative toxicity of polyglutamine, polyalanine and polyleucine tracts in Drosophila models of expanded repeat disease","volume":"21","author":"van Eyk","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C17","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.molcel.2005.09.002","article-title":"Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF","volume":"20","author":"Cho","year":"2005","journal-title":"Mol. Cell"},{"key":"key\n\t\t\t\t20170522153949_DDT130C18","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1038\/ng1827","article-title":"Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8","volume":"38","author":"Moseley","year":"2006","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C19","doi-asserted-by":"crossref","first-page":"3174","DOI":"10.1093\/hmg\/ddm293","article-title":"An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals","volume":"16","author":"Ladd","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C20","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1093\/hmg\/ddr263","article-title":"A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression","volume":"20","author":"Chung","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C21","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.neuron.2011.05.027","article-title":"CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA","volume":"70","author":"Sopher","year":"2011","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522153949_DDT130C22","doi-asserted-by":"crossref","first-page":"e1002481","DOI":"10.1371\/journal.pgen.1002481","article-title":"A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity","volume":"8","author":"Banez-Coronel","year":"2012","journal-title":"PLoS Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C23","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1084\/jem.20080178","article-title":"A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease","volume":"205","author":"Bjorkqvist","year":"2008","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170522153949_DDT130C24","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1186\/1742-2094-9-238","article-title":"Carriers of the fragile X mental retardation 1 (FMR1) premutation allele present with increased levels of cytokine IL-10","volume":"9","author":"Marek","year":"2012","journal-title":"J. Neuroinflammation"},{"key":"key\n\t\t\t\t20170522153949_DDT130C25","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1101\/gad.8.15.1787","article-title":"Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion","volume":"8","author":"Luo","year":"1994","journal-title":"Genes & Development"},{"key":"key\n\t\t\t\t20170522153949_DDT130C26","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0896-6273(03)00533-6","article-title":"RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila","volume":"39","author":"Jin","year":"2003","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522153949_DDT130C27","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.cub.2004.01.034","article-title":"The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila","volume":"14","author":"Mutsuddi","year":"2004","journal-title":"Curr. Biol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C28","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1093\/hmg\/ddi080","article-title":"Myotonic dystrophy associated expanded CUG repeat muscleblind positive ribonuclear foci are not toxic to Drosophila","volume":"14","author":"Houseley","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C29","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1093\/hmg\/ddl137","article-title":"MBNL1 and CUGBP1 modify expanded CUG-induced toxicity in a Drosophila model of myotonic dystrophy type 1","volume":"15","author":"de Haro","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C30","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1093\/hmg\/ddm186","article-title":"Argonaute-2-dependent rescue of a Drosophila model of FXTAS by FRAXE premutation repeat","volume":"16","author":"Sofola","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C31","doi-asserted-by":"crossref","first-page":"e1466","DOI":"10.1371\/journal.pone.0001466","article-title":"Repeat length and RNA expression level are not primary determinants in CUG expansion toxicity in Drosophila models","volume":"3","author":"Le Mee","year":"2008","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170522153949_DDT130C32","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0092-8674(00)81385-9","article-title":"Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye","volume":"87","author":"Freeman","year":"1996","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522153949_DDT130C33","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1534\/genetics.109.103630","article-title":"A Drosophila resource of transgenic RNAi lines for neurogenetics","volume":"182","author":"Ni","year":"2009","journal-title":"Genetics"},{"key":"key\n\t\t\t\t20170522153949_DDT130C34","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nmeth1146","article-title":"Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster","volume":"5","author":"Ni","year":"2008","journal-title":"Nat. Methods"},{"key":"key\n\t\t\t\t20170522153949_DDT130C35","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1038\/78531","article-title":"Heritable gene silencing in Drosophila using double-stranded RNA","volume":"18","author":"Kennerdell","year":"2000","journal-title":"Nat. Biotechnol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C36","doi-asserted-by":"crossref","first-page":"a000232","DOI":"10.1101\/cshperspect.a000232","article-title":"NF-kappaB in the immune response of Drosophila","volume":"1","author":"Hetru","year":"2009","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C37","doi-asserted-by":"crossref","first-page":"12590","DOI":"10.1073\/pnas.221458698","article-title":"Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays","volume":"98","author":"De Gregorio","year":"2001","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522153949_DDT130C38","doi-asserted-by":"crossref","first-page":"15119","DOI":"10.1073\/pnas.261573998","article-title":"A genome-wide analysis of immune responses in Drosophila","volume":"98","author":"Irving","year":"2001","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522153949_DDT130C39","doi-asserted-by":"crossref","first-page":"4578","DOI":"10.1128\/MCB.01814-06","article-title":"Toll and IMD pathways synergistically activate an innate immune response in Drosophila melanogaster","volume":"27","author":"Tanji","year":"2007","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C40","doi-asserted-by":"crossref","first-page":"4860","DOI":"10.1038\/sj.onc.1206715","article-title":"Eiger and its receptor, Wengen, comprise a TNF-like system in Drosophila","volume":"22","author":"Kauppila","year":"2003","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20170522153949_DDT130C41","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1083\/jcb.200508072","article-title":"Expression of mutant Huntingtin in glial cells contributes to neuronal excitotoxicity","volume":"171","author":"Shin","year":"2005","journal-title":"J. Cell Biol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C42","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s004010050933","article-title":"Hereditary dentatorubral-pallidoluysian atrophy: detection of widespread ubiquitinated neuronal and glial intranuclear inclusions in the brain","volume":"96","author":"Hayashi","year":"1998","journal-title":"Acta Neuropathol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C43","doi-asserted-by":"crossref","first-page":"10653","DOI":"10.1074\/jbc.M109.083287","article-title":"Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice","volume":"285","author":"Bradford","year":"2010","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522153949_DDT130C44","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/glia.20098","article-title":"Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila","volume":"49","author":"Kretzschmar","year":"2005","journal-title":"Glia"},{"key":"key\n\t\t\t\t20170522153949_DDT130C45","doi-asserted-by":"crossref","first-page":"e4262","DOI":"10.1371\/journal.pone.0004262","article-title":"Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models","volume":"4","author":"Tamura","year":"2009","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170522153949_DDT130C46","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1006\/dbio.2001.0411","article-title":"Peripheral glia direct axon guidance across the CNS\/PNS transition zone","volume":"238","author":"Sepp","year":"2001","journal-title":"Dev. Biol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C47","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/nature09782","article-title":"Autophagy in immunity and inflammation","volume":"469","author":"Levine","year":"2011","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522153949_DDT130C48","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.it.2007.02.002","article-title":"RIG-I: tri-ing to discriminate between self and non-self RNA","volume":"28","author":"Bowie","year":"2007","journal-title":"TRENDS Immunol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C49","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.dci.2011.03.034","article-title":"Identification of putative miRNA involved in Drosophila melanogaster immune response","volume":"36","author":"Fullaondo","year":"2012","journal-title":"Dev. Comp. Immunol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C50","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/ng1362","article-title":"Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease","volume":"36","author":"Ravikumar","year":"2004","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C51","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1371\/journal.pgen.0030177","article-title":"Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila","volume":"3","author":"Bilen","year":"2007","journal-title":"PLoS Genet."},{"key":"key\n\t\t\t\t20170522153949_DDT130C52","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/brain\/awp292","article-title":"Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3","volume":"133","author":"Menzies","year":"2010","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170522153949_DDT130C53","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.immuni.2007.05.022","article-title":"Toll-like receptor 4 is a sensor for autophagy associated with innate immunity","volume":"27","author":"Xu","year":"2007","journal-title":"Immunity"},{"key":"key\n\t\t\t\t20170522153949_DDT130C54","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1038\/emboj.2008.31","article-title":"Toll-like receptors control autophagy","volume":"27","author":"Delgado","year":"2008","journal-title":"EMBO J"},{"key":"key\n\t\t\t\t20170522153949_DDT130C55","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.immuni.2012.03.003","article-title":"Virus recognition by Toll-7 activates antiviral autophagy in Drosophila","volume":"36","author":"Nakamoto","year":"2012","journal-title":"Immunity"},{"key":"key\n\t\t\t\t20170522153949_DDT130C56","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/j.cellsig.2012.01.020","article-title":"Autophagy in regulation of Toll-like receptor signaling","volume":"24","author":"Into","year":"2012","journal-title":"Cell Signal."},{"key":"key\n\t\t\t\t20170522153949_DDT130C57","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nature10992","article-title":"Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure","volume":"485","author":"Oka","year":"2012","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522153949_DDT130C58","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1111\/j.1471-4159.2009.06537.x","article-title":"Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders","volume":"112","author":"von Bernhardi","year":"2010","journal-title":"J. Neurochem."},{"key":"key\n\t\t\t\t20170522153949_DDT130C59","doi-asserted-by":"crossref","first-page":"7999","DOI":"10.1523\/JNEUROSCI.2675-04.2004","article-title":"Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity","volume":"24","author":"Khoshnan","year":"2004","journal-title":"J. Neurosci."},{"key":"key\n\t\t\t\t20170522153949_DDT130C60","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0304-3940(97)00967-1","article-title":"Increased peripheral benzodiazepine binding sites in the brain of patients with Huntington's disease","volume":"241","author":"Messmer","year":"1998","journal-title":"Neurosci. Lett."},{"key":"key\n\t\t\t\t20170522153949_DDT130C61","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/jnen\/60.2.161","article-title":"Early and progressive accumulation of reactive microglia in the Huntington disease brain","volume":"60","author":"Sapp","year":"2001","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"key\n\t\t\t\t20170522153949_DDT130C62","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1212\/01.wnl.0000222734.56412.17","article-title":"Microglial activation correlates with severity in Huntington disease: a clinical and PET study","volume":"66","author":"Pavese","year":"2006","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170522153949_DDT130C63","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1093\/brain\/awm044","article-title":"Microglial activation in presymptomatic Huntington's disease gene carriers","volume":"130","author":"Tai","year":"2007","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170522153949_DDT130C64","doi-asserted-by":"crossref","first-page":"3312","DOI":"10.1073\/pnas.0611511104","article-title":"An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases","volume":"104","author":"Bischof","year":"2007","journal-title":"Proc. Natl Acad. Sci. USA"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/22\/14\/2811\/17259070\/ddt130.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T08:14:33Z","timestamp":1562832873000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddt130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,21]]},"references-count":64,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2013,3,21]]},"published-print":{"date-parts":[[2013,7,15]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddt130","relation":{},"ISSN":["1460-2083","0964-6906"],"issn-type":[{"value":"1460-2083","type":"electronic"},{"value":"0964-6906","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3,21]]}}}