{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:45:00Z","timestamp":1790775900336,"version":"4.1.0"},"reference-count":51,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Molecular Genetics"],"published-print":{"date-parts":[[2014,1,15]]},"DOI":"10.1093\/hmg\/ddt421","type":"journal-article","created":{"date-parts":[[2013,9,5]],"date-time":"2013-09-05T22:11:27Z","timestamp":1378419087000},"page":"303-318","source":"Crossref","is-referenced-by-count":66,"title":["Rescue of behavioral and EEG deficits in male and female Mecp2-deficient mice by delayed Mecp2 gene reactivation"],"prefix":"10.1093","volume":"23","author":[{"given":"M.","family":"Lang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. G.","family":"Wither","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Colic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. P.","family":"Monnier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. L.","family":"Bardakjian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. H.","family":"Eubanks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,9,5]]},"reference":[{"issue":"2","key":"1_10984879","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1038\/13810","volume":"23","author":"Amir","year":"1999","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"29","key":"2_43199162","doi-asserted-by":"publisher","first-page":"10021","DOI":"10.1523\/JNEUROSCI.1316-12.2012","volume":"32","author":"Nguyen","year":"2012","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"17","key":"3_42746646","doi-asserted-by":"publisher","first-page":"3806","DOI":"10.1093\/hmg\/dds208","volume":"21","year":"2012","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"6039","key":"4_40040587","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1126\/science.1206593","volume":"333","year":"2011","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"3","key":"5_18501856","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.mcn.2004.07.006","volume":"27","author":"Kishi","year":"2004","journal-title":"Molecular and cellular neurosciences","ISSN":"https:\/\/id.crossref.org\/issn\/1044-7431","issn-type":"print"},{"key":"6_46505184","doi-asserted-by":"crossref","first-page":"253","DOI":"10.31887\/DCNS.2012.14.3\/jneul","volume":"14","year":"2012","ISSN":"https:\/\/id.crossref.org\/issn\/1294-8322","issn-type":"print"},{"issue":"3","key":"7_17647867","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/S0887-8994(02)00624-0","volume":"28","author":"Carney","year":"2003","journal-title":"Pediatric neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0887-8994","issn-type":"print"},{"issue":"4","key":"8_28544991","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.4161\/epi.1.1.2642","volume":"1","author":"Nagarajan","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1559-2308","issn-type":"print"},{"issue":"3","key":"9_11061300","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1038\/85899","volume":"27","author":"Guy","year":"2001","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"3","key":"10_11061301","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1038\/85906","volume":"27","author":"Chen","year":"2001","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"2","key":"11_17179562","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/S0896-6273(02)00768-7","volume":"35","author":"Shahbazian","year":"2002","journal-title":"Neuron","ISSN":"https:\/\/id.crossref.org\/issn\/0896-6273","issn-type":"print"},{"issue":"4","key":"12_21589835","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1093\/brain\/awl022","volume":"129","year":"2006","journal-title":"Brain","ISSN":"https:\/\/id.crossref.org\/issn\/0006-8950","issn-type":"print"},{"issue":"4","key":"13_38770810","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/s00109-010-0704-4","volume":"89","author":"Brendel","year":"2011","journal-title":"Journal of molecular medicine (Berlin, Germany)","ISSN":"https:\/\/id.crossref.org\/issn\/0377-046X","issn-type":"print"},{"key":"14_46505185","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/nn.2997","volume":"15","year":"2011","journal-title":"Nature neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/1097-6256","issn-type":"print"},{"key":"15_29832032","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.brainres.2007.08.039","volume":"1180","author":"Lawson-Yuen","year":"2007","journal-title":"Brain research","ISSN":"https:\/\/id.crossref.org\/issn\/0006-8993","issn-type":"print"},{"issue":"5815","key":"16_23617388","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1126\/science.1138389","volume":"315","year":"2007","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"6","key":"17_44063422","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1242\/dmm.011007","volume":"5","author":"Katz","year":"2012","journal-title":"Disease Models & Mechanisms","ISSN":"https:\/\/id.crossref.org\/issn\/1754-8403","issn-type":"print"},{"issue":"40","key":"18_43775465","doi-asserted-by":"publisher","first-page":"13860","DOI":"10.1523\/JNEUROSCI.2159-12.2012","volume":"32","author":"Kron","year":"2012","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"4","key":"19_42433814","doi-asserted-by":"publisher","first-page":"e35396","DOI":"10.1371\/journal.pone.0035396","volume":"7","author":"Wither","year":"2012","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"39","key":"20_35661717","doi-asserted-by":"publisher","first-page":"12187","DOI":"10.1523\/JNEUROSCI.3156-09.2009","volume":"29","author":"Taneja","year":"2009","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"1","key":"21_21339747","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1523\/JNEUROSCI.2623-05.2006","volume":"26","author":"Moretti","year":"2006","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"35","key":"22_19690565","doi-asserted-by":"publisher","first-page":"12560","DOI":"10.1073\/pnas.0506071102","volume":"102","year":"2005","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"1","key":"23_36363679","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.nbd.2009.12.018","volume":"38","author":"D'Cruz","year":"2010","journal-title":"Neurobiology of disease","ISSN":"https:\/\/id.crossref.org\/issn\/0969-9961","issn-type":"print"},{"issue":"12","key":"24_15648024","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1097\/00001756-199407000-00025","volume":"5","author":"Belichenko","year":"1994","journal-title":"Neuroreport","ISSN":"https:\/\/id.crossref.org\/issn\/0959-4965","issn-type":"print"},{"key":"25_46505186","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s004010050582","volume":"93","year":"1997","journal-title":"ACTA NEUROPATH"},{"issue":"13","key":"26_34460351","doi-asserted-by":"publisher","first-page":"4218","DOI":"10.1523\/JNEUROSCI.4225-08.2009","volume":"29","author":"Adachi","year":"2009","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"1","key":"27_29589923","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.neuron.2007.08.018","volume":"56","author":"Chao","year":"2007","journal-title":"Neuron","ISSN":"https:\/\/id.crossref.org\/issn\/0896-6273","issn-type":"print"},{"issue":"3","key":"28_30543068","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1002\/hipo.20389","volume":"18","author":"Zhang","year":"2008","journal-title":"Hippocampus","ISSN":"https:\/\/id.crossref.org\/issn\/1050-9631","issn-type":"print"},{"issue":"1","key":"29_43781699","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1093\/hmg\/dds406","volume":"22","year":"2013","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"9","key":"30_42423405","doi-asserted-by":"publisher","first-page":"2699","DOI":"10.1093\/brain\/aws096","volume":"135","year":"2012","journal-title":"Brain","ISSN":"https:\/\/id.crossref.org\/issn\/0006-8950","issn-type":"print"},{"issue":"2","key":"31_17001892","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1006\/dbio.2002.0597","volume":"244","author":"Hayashi","year":"2002","journal-title":"Developmental biology","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1606","issn-type":"print"},{"issue":"7128","key":"32_23635437","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1038\/nature05541","volume":"445","author":"Ventura","year":"2007","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"28","key":"33_40309224","doi-asserted-by":"publisher","first-page":"10359","DOI":"10.1523\/JNEUROSCI.0057-11.2011","volume":"31","author":"Ward","year":"2011","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"2","key":"34_43957708","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1093\/hmg\/dds433","volume":"22","year":"2013","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"key":"35_46344094","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.expneurol.2012.09.005","volume":"239","year":"2013","journal-title":"Experimental neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0014-4886","issn-type":"print"},{"issue":"2","key":"36_36118737","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1111\/j.1601-183X.2009.00551.x","volume":"9","author":"De Filippis","year":"2010","journal-title":"Genes, brain, and behavior","ISSN":"https:\/\/id.crossref.org\/issn\/1601-1848","issn-type":"print"},{"issue":"3","key":"37_29854530","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/j.neuron.2007.10.001","volume":"56","author":"Chahrour","year":"2007","journal-title":"Neuron","ISSN":"https:\/\/id.crossref.org\/issn\/0896-6273","issn-type":"print"},{"issue":"1","key":"38_35846173","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/s10519-009-9303-y","volume":"40","author":"Roux","year":"2010","journal-title":"Behavior genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0001-8244","issn-type":"print"},{"issue":"10","key":"39_30333683","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1093\/hmg\/ddn026","volume":"17","year":"2008","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"51","key":"40_36151871","doi-asserted-by":"publisher","first-page":"21966","DOI":"10.1073\/pnas.0912257106","volume":"106","year":"2009","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"7357","key":"41_40253655","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1038\/nature10214","volume":"475","author":"Lioy","year":"2011","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"key":"42_28008737","doi-asserted-by":"crossref","first-page":"S206","DOI":"10.1016\/S0387-7604(01)00351-5","volume":"23","year":"2001","journal-title":"Brain & development","ISSN":"https:\/\/id.crossref.org\/issn\/0387-7604","issn-type":"print"},{"issue":"1","key":"43_28946249","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.nbd.2007.04.005","volume":"27","author":"Smrt","year":"2007","journal-title":"Neurobiology of disease","ISSN":"https:\/\/id.crossref.org\/issn\/0969-9961","issn-type":"print"},{"issue":"2","key":"44_17745214","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1002\/ana.10633","volume":"54","author":"Ronnett","year":"2003","journal-title":"Annals of neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0364-5134","issn-type":"print"},{"issue":"3","key":"45_22166210","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.gde.2006.04.009","volume":"16","author":"Moretti","year":"2006","journal-title":"Current opinion in genetics & development","ISSN":"https:\/\/id.crossref.org\/issn\/0959-437X","issn-type":"print"},{"issue":"4","key":"46_39156616","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1152\/jn.00800.2010","volume":"105","year":"2011","journal-title":"Journal of Neurophysiology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3077","issn-type":"print"},{"issue":"5","key":"47_14370030","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/S0387-7604(87)80078-5","volume":"9","author":"Naidu","year":"1987","journal-title":"Brain & development","ISSN":"https:\/\/id.crossref.org\/issn\/0387-7604","issn-type":"print"},{"issue":"4","key":"48_22546031","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1203\/01.pdr.0000238302.84552.d0","volume":"60","year":"2006","journal-title":"Pediatric Research","ISSN":"https:\/\/id.crossref.org\/issn\/0031-3998","issn-type":"print"},{"issue":"6","key":"49_23584926","doi-asserted-by":"publisher","first-page":"1931","DOI":"10.1073\/pnas.0610593104","volume":"104","year":"2007","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"1","key":"50_10401229","doi-asserted-by":"crossref","first-page":"52","DOI":"10.2144\/00291bm09","volume":"29","author":"Truett","year":"2000","journal-title":"BioTechniques","ISSN":"https:\/\/id.crossref.org\/issn\/0736-6205","issn-type":"print"},{"issue":"1","key":"51_31012355","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.jneumeth.2008.03.001","volume":"171","author":"Wu","year":"2008","journal-title":"Journal of neuroscience methods","ISSN":"https:\/\/id.crossref.org\/issn\/0165-0270","issn-type":"print"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/23\/2\/303\/1881440\/ddt421.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T11:47:13Z","timestamp":1646480833000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddt421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,5]]},"references-count":51,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,12,20]]},"published-print":{"date-parts":[[2014,1,15]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddt421","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718100796.793517467","asserted-by":"object"}]},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,5]]}}}