{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T23:38:29Z","timestamp":1791157109189,"version":"4.1.0"},"reference-count":60,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Molecular Genetics"],"published-print":{"date-parts":[[2014,5,15]]},"DOI":"10.1093\/hmg\/ddt667","type":"journal-article","created":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T02:01:28Z","timestamp":1388541688000},"page":"2737-2751","source":"Crossref","is-referenced-by-count":54,"title":["Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of Huntington's disease"],"prefix":"10.1093","volume":"23","author":[{"given":"M.","family":"Maheshwari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Bhutani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Kino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Nukina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. R.","family":"Jana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,12,30]]},"reference":[{"key":"1_29266618","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1146\/annurev.neuro.29.051605.113042","volume":"30","author":"Orr","year":"2007","journal-title":"Annual review of neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0147-006X","issn-type":"print"},{"issue":"1","key":"2_16161573","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1136\/jnnp.60.1.78","volume":"60","author":"Xuereb","year":"1996","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3050","issn-type":"print"},{"key":"3_47246562","first-page":"743","volume":"6","year":"2005","journal-title":"NAT REV"},{"issue":"1","key":"4_15723409","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1097\/00005072-199501000-00013","volume":"54","author":"Hedreen","year":"1995","journal-title":"Journal of neuropathology and experimental neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3069","issn-type":"print"},{"issue":"5","key":"5_6008045","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1097\/00005072-199805000-00001","volume":"57","author":"Vonsattel","year":"1998","journal-title":"Journal of neuropathology and experimental neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3069","issn-type":"print"},{"issue":"6","key":"6_10182174","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","volume":"72","year":"1993","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"6330","key":"7_9500174","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1038\/352077a0","volume":"352","author":"La Spada","year":"1991","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"3","key":"8_14426573","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1038\/ng0793-221","volume":"4","author":"Orr","year":"1993","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"1","key":"9_14698029","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/ng0194-9","volume":"6","author":"Koide","year":"1994","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"3","key":"10_15786600","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1038\/ng1194-221","volume":"8","author":"Kawaguchi","year":"1994","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"5334","key":"11_5743041","doi-asserted-by":"publisher","first-page":"1990","DOI":"10.1126\/science.277.5334.1990","volume":"277","author":"DiFiglia","year":"1997","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"key":"12_39531545","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1146\/annurev-biochem-060809-095203","volume":"80","author":"Anckar","year":"2011","journal-title":"Annual review of biochemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0066-4154","issn-type":"print"},{"issue":"1-3","key":"13_17011910","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/S0014-5793(02)02470-5","volume":"516","author":"Yokoyama","year":"2002","journal-title":"FEBS Letters","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3468","issn-type":"print"},{"issue":"5622","key":"14_17631004","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1126\/science.1083701","volume":"300","author":"Hsu","year":"2003","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"2","key":"15_18017392","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1091\/mbc.E03-07-0532","volume":"15","year":"2004","journal-title":"Molecular Biology of the Cell","ISSN":"https:\/\/id.crossref.org\/issn\/1059-1524","issn-type":"print"},{"issue":"2","key":"16_6033278","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1038\/502","volume":"19","author":"Cummings","year":"1998","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"13","key":"17_10434115","doi-asserted-by":"publisher","first-page":"2009","DOI":"10.1093\/hmg\/9.13.2009","volume":"9","author":"Jana","year":"2000","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"4","key":"18_37686030","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1093\/hmg\/8.4.673","volume":"8","year":"1999","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"4","key":"19_6384788","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1038\/70532","volume":"23","author":"Warrick","year":"1999","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"19","key":"20_10562407","doi-asserted-by":"publisher","first-page":"2811","DOI":"10.1093\/hmg\/9.19.2811","volume":"9","author":"Chan","year":"2000","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"5459","key":"21_6504497","doi-asserted-by":"publisher","first-page":"1837","DOI":"10.1126\/science.287.5459.1837","volume":"287","author":"Kazemi-Esfarjani","year":"2000","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"9","key":"22_17025407","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1093\/hmg\/11.9.1137","volume":"11","author":"Wyttenbach","year":"2002","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"1-2","key":"23_17594193","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/S0006-8993(02)04275-0","volume":"970","author":"Hansson","year":"2003","journal-title":"Brain research","ISSN":"https:\/\/id.crossref.org\/issn\/0006-8993","issn-type":"print"},{"issue":"6","key":"24_28739433","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1038\/sj.mt.6300163","volume":"15","author":"Howarth","year":"2007","journal-title":"Molecular therapy : the journal of the American Society of Gene Therapy","ISSN":"https:\/\/id.crossref.org\/issn\/1525-0016","issn-type":"print"},{"issue":"9","key":"25_27621265","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1093\/hmg\/ddm057","volume":"16","year":"2007","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"4","key":"26_42047677","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1093\/brain\/aws022","volume":"135","year":"2012","journal-title":"Brain","ISSN":"https:\/\/id.crossref.org\/issn\/0006-8950","issn-type":"print"},{"issue":"12","key":"27_6515678","doi-asserted-by":"publisher","first-page":"8772","DOI":"10.1074\/jbc.275.12.8772","volume":"275","author":"Kobayashi","year":"2000","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"14","key":"28_19669743","doi-asserted-by":"publisher","first-page":"7841","DOI":"10.1073\/pnas.140202897","volume":"97","year":"2000","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"5","key":"29_16940786","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1093\/hmg\/11.5.515","volume":"11","author":"Bailey","year":"2002","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"13","key":"30_18372519","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1093\/hmg\/ddh144","volume":"13","year":"2004","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"4","key":"31_6139353","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/S0092-8674(00)81588-3","volume":"94","author":"Zou","year":"1998","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"12","key":"32_11193821","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1093\/hmg\/10.12.1307","volume":"10","author":"Sittler","year":"2001","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"38","key":"33_31535454","doi-asserted-by":"publisher","first-page":"26188","DOI":"10.1074\/jbc.M710521200","volume":"283","year":"2008","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"8","key":"34_40409849","doi-asserted-by":"publisher","first-page":"3306","DOI":"10.1172\/JCI57413","volume":"121","author":"Labbadia","year":"2011","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"53","key":"35_19572418","doi-asserted-by":"publisher","first-page":"56053","DOI":"10.1074\/jbc.M409267200","volume":"279","year":"2004","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"41","key":"36_19576557","doi-asserted-by":"publisher","first-page":"34908","DOI":"10.1074\/jbc.M506288200","volume":"280","year":"2005","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"1","key":"37_36489131","doi-asserted-by":"publisher","first-page":"e1000291","DOI":"10.1371\/journal.pbio.1000291","volume":"8","author":"Neef","year":"2010","journal-title":"PLoS biology","ISSN":"https:\/\/id.crossref.org\/issn\/1544-9173","issn-type":"print"},{"issue":"6","key":"38_46505517","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1038\/emboj.2008.23","volume":"27","author":"Yamanaka","year":"2008","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"},{"issue":"4","key":"39_6540758","doi-asserted-by":"crossref","first-page":"H1091","DOI":"10.1152\/ajpheart.2000.278.4.H1091","volume":"278","author":"Sun","year":"2000","journal-title":"American Journal of Physiology - Heart and Circulatory Physiology","ISSN":"https:\/\/id.crossref.org\/issn\/0363-6135","issn-type":"print"},{"issue":"1","key":"40_11008506","doi-asserted-by":"crossref","first-page":"H455","DOI":"10.1152\/ajpheart.2001.280.1.H455","volume":"280","author":"Knowlton","year":"2001","journal-title":"American Journal of Physiology - Heart and Circulatory Physiology","ISSN":"https:\/\/id.crossref.org\/issn\/0363-6135","issn-type":"print"},{"issue":"4","key":"41_19388065","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1002\/cne.20680","volume":"490","author":"Stack","year":"2005","journal-title":"The Journal of comparative neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9967","issn-type":"print"},{"issue":"3","key":"42_6178871","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/S0896-6273(00)80573-5","volume":"21","author":"Jackson","year":"1998","journal-title":"Neuron","ISSN":"https:\/\/id.crossref.org\/issn\/0896-6273","issn-type":"print"},{"issue":"4","key":"43_42593333","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/j.cell.2012.02.061","volume":"149","author":"Sawarkar","year":"2012","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"16","key":"44_22458150","doi-asserted-by":"publisher","first-page":"2183","DOI":"10.1101\/gad.1436506","volume":"20","author":"Riley","year":"2006","journal-title":"Genes & Development","ISSN":"https:\/\/id.crossref.org\/issn\/0890-9369","issn-type":"print"},{"issue":"5","key":"45_42759394","doi-asserted-by":"publisher","first-page":"e37929","DOI":"10.1371\/journal.pone.0037929","volume":"7","author":"Chafekar","year":"2012","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"key":"46_43215917","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/nm.2558","volume":"18","year":"2011","journal-title":"Nature medicine","ISSN":"https:\/\/id.crossref.org\/issn\/1078-8956","issn-type":"print"},{"issue":"6","key":"47_30282230","doi-asserted-by":"publisher","first-page":"2003","DOI":"10.1096\/fj.07-099689","volume":"22","year":"2008","journal-title":"The FASEB Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0892-6638","issn-type":"print"},{"key":"48_47246563","first-page":"3459","volume":"29","year":"2012","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"},{"issue":"14","key":"49_46789620","doi-asserted-by":"publisher","first-page":"3800","DOI":"10.1093\/emboj\/20.14.3800","volume":"20","author":"Holmberg","year":"2001","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"},{"issue":"30","key":"50_29078966","doi-asserted-by":"publisher","first-page":"7974","DOI":"10.1523\/JNEUROSCI.0006-07.2007","volume":"27","author":"Homma","year":"2007","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"2","key":"51_11050860","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/jnen\/60.2.161","volume":"60","author":"Sapp","year":"2001","journal-title":"Journal of neuropathology and experimental neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3069","issn-type":"print"},{"issue":"3","key":"52_17750535","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1002\/glia.10261","volume":"43","author":"Ma","year":"2003","journal-title":"Glia","ISSN":"https:\/\/id.crossref.org\/issn\/0894-1491","issn-type":"print"},{"issue":"3","key":"53_33884747","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1111\/j.1471-4159.2008.05823.x","volume":"108","author":"Godavarthi","year":"2009","journal-title":"Journal of neurochemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3042","issn-type":"print"},{"issue":"14","key":"54_19669768","doi-asserted-by":"publisher","first-page":"8093","DOI":"10.1073\/pnas.110078997","volume":"97","year":"2000","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"3","key":"55_16491653","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/S0092-8674(00)81369-0","volume":"87","author":"Mangiarini","year":"1996","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"13","key":"57_17680595","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.1093\/hmg\/ddg169","volume":"12","author":"Slow","year":"2003","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"35","key":"58_43086465","doi-asserted-by":"publisher","first-page":"29949","DOI":"10.1074\/jbc.M112.371724","volume":"287","year":"2012","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"12","key":"59_19573436","doi-asserted-by":"publisher","first-page":"11635","DOI":"10.1074\/jbc.M412042200","volume":"280","year":"2005","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"23","key":"60_38150526","doi-asserted-by":"publisher","first-page":"4726","DOI":"10.1093\/hmg\/ddq407","volume":"19","year":"2010","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"12","key":"61_30296998","doi-asserted-by":"publisher","first-page":"7648","DOI":"10.1074\/jbc.M706620200","volume":"283","year":"2008","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/23\/10\/2737\/1697426\/ddt667.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T17:42:59Z","timestamp":1565026979000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddt667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,30]]},"references-count":60,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2014,4,17]]},"published-print":{"date-parts":[[2014,5,15]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddt667","relation":{},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,30]]}}}