{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T13:53:17Z","timestamp":1789912397773,"version":"4.0.1"},"reference-count":65,"publisher":"Oxford University Press (OUP)","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,8,15]]},"DOI":"10.1093\/hmg\/ddu151","type":"journal-article","created":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T23:06:58Z","timestamp":1396566418000},"page":"4328-4344","source":"Crossref","is-referenced-by-count":113,"title":["Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease"],"prefix":"10.1093","volume":"23","author":[{"given":"Han-Yun","family":"Hsiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-Lan","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiung-Mei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yih-Ru","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Mei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Chih","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijuang","family":"Chern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,4,3]]},"reference":[{"key":"key\n\t\t\t\t20170522154447_DDU151C1","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1084\/jem.20080178","article-title":"A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease","volume":"205","author":"Bjorkqvist","year":"2008","journal-title":"J. Exp. Med."},{"key":"key\n\t\t\t\t20170522154447_DDU151C2","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0969-9961(03)00087-1","article-title":"Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis","volume":"14","author":"Hensley","year":"2003","journal-title":"Neurobiol. Dis."},{"key":"key\n\t\t\t\t20170522154447_DDU151C3","doi-asserted-by":"crossref","first-page":"9365","DOI":"10.1523\/JNEUROSCI.1504-06.2006","article-title":"Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease","volume":"26","author":"McCoy","year":"2006","journal-title":"J. Neurosci."},{"key":"key\n\t\t\t\t20170522154447_DDU151C4","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1080\/13550280290100969","article-title":"Local neuroinflammation and the progression of Alzheimer's disease","volume":"8","author":"McGeer","year":"2002","journal-title":"J. Neurovirol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C5","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1093\/brain\/awm044","article-title":"Microglial activation in presymptomatic Huntington's disease gene carriers","volume":"130","author":"Tai","year":"2007","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170522154447_DDU151C6","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1093\/hmg\/ddt036","article-title":"A critical role of astrocyte-mediated nuclear factor-kappaB-dependent inflammation in Huntington's disease","volume":"22","author":"Hsiao","year":"2013","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522154447_DDU151C7","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1002\/ana.10818","article-title":"Minocycline is not beneficial in a phenotypic mouse model of Huntington's disease","volume":"54","author":"Diguet","year":"2003","journal-title":"Ann. Neurol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C8","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1002\/ana.21891","article-title":"Minocycline is protective in a mouse model of Huntington's disease","volume":"54","author":"Hersch","year":"2003","journal-title":"Ann. Neurol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C9","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/ana.10614","article-title":"Minocycline and doxycycline are not beneficial in a model of Huntington's disease","volume":"54","author":"Smith","year":"2003","journal-title":"Ann. Neurol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C10","doi-asserted-by":"crossref","first-page":"10483","DOI":"10.1073\/pnas.1832501100","article-title":"Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease","volume":"100","author":"Wang","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522154447_DDU151C11","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0898-6568(01)00262-5","article-title":"TNF receptor subtype signalling: differences and cellular consequences","volume":"14","author":"MacEwan","year":"2002","journal-title":"Cell. Signal."},{"key":"key\n\t\t\t\t20170522154447_DDU151C12","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/nri1184","article-title":"Signalling pathways of the TNF superfamily: a double-edged sword","volume":"3","author":"Aggarwal","year":"2003","journal-title":"Nat. Rev. Immunol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C13","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1002\/eji.200635921","article-title":"Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity","volume":"36","author":"Alexopoulou","year":"2006","journal-title":"Eur. J. Immunol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C14","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1038\/nn738","article-title":"TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination","volume":"4","author":"Arnett","year":"2001","journal-title":"Nat. Neurosci."},{"key":"key\n\t\t\t\t20170522154447_DDU151C15","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.atherosclerosis.2003.10.004","article-title":"Exclusive expression of transmembrane TNF-alpha in mice reduces the inflammatory response in early lipid lesions of aortic sinus","volume":"172","author":"Canault","year":"2004","journal-title":"Atherosclerosis"},{"key":"key\n\t\t\t\t20170522154447_DDU151C16","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/glia.440130305","article-title":"The receptor for tumor necrosis factor on murine astrocytes-enriched culture: characterization, intracellular degradation, and regulation by cytokines and Theiler's murine encephalomyelitis virus","volume":"13","author":"Aranguez","year":"1995","journal-title":"Glia"},{"key":"key\n\t\t\t\t20170522154447_DDU151C17","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/BF03401714","article-title":"Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia","volume":"3","author":"Botchkina","year":"1997","journal-title":"Mol. Med."},{"key":"key\n\t\t\t\t20170522154447_DDU151C18","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1093\/hmg\/ddi178","article-title":"Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection","volume":"14","author":"Chung","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522154447_DDU151C19","doi-asserted-by":"crossref","first-page":"6348","DOI":"10.1073\/pnas.86.16.6348","article-title":"Production of tumor necrosis factor and other cytokines by astrocytes-enriched culture stimulated with lipopolysaccharide or a neurotropic virus","volume":"86","author":"Lieberman","year":"1989","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522154447_DDU151C20","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/sj.mp.4000227","article-title":"Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue","volume":"2","author":"Morganti-Kossman","year":"1997","journal-title":"Mol. Psychiatry."},{"key":"key\n\t\t\t\t20170522154447_DDU151C21","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1212\/WNL.45.6_Suppl_6.S44","article-title":"Experimental autoimmune encephalomyelitis: immunotherapy with anti-tumor necrosis factor antibodies and soluble tumor necrosis factor receptors","volume":"45","author":"Selmaj","year":"1995","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170522154447_DDU151C22","first-page":"25","article-title":"TNF-alpha modulation for treatment of Alzheimer's disease: a 6-month pilot study","volume":"8","author":"Tobinick","year":"2006","journal-title":"MedGenMed"},{"key":"key\n\t\t\t\t20170522154447_DDU151C23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/nrrheum.2009.279","article-title":"Tumor necrosis factor blockade and the risk of viral infection","volume":"6","author":"Kim","year":"2010","journal-title":"Nat. Rev. Rheumatol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C24","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1159\/000289205","article-title":"The first decade of biologic TNF antagonists in clinical practice: lessons learned, unresolved issues and future directions","volume":"11","author":"Sfikakis","year":"2010","journal-title":"Curr. Dir. Autoimmun."},{"key":"key\n\t\t\t\t20170522154447_DDU151C25","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/QCO.0b013e32832dda55","article-title":"Infectious complications of tumor necrosis factor blockade","volume":"22","author":"Wallis","year":"2009","journal-title":"Curr. Opin. Infect. Dis."},{"key":"key\n\t\t\t\t20170522154447_DDU151C26","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1126\/science.1081297","article-title":"Inactivation of TNF signaling by rationally designed dominant-negative TNF variants","volume":"301","author":"Steed","year":"2003","journal-title":"Science"},{"key":"key\n\t\t\t\t20170522154447_DDU151C27","first-page":"590","article-title":"Creating the next generation of protein therapeutics through rational drug design","volume":"8","author":"Szymkowski","year":"2005","journal-title":"Curr. Opin. Drug Discov. Dev."},{"key":"key\n\t\t\t\t20170522154447_DDU151C28","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.4049\/jimmunol.179.3.1872","article-title":"Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection","volume":"179","author":"Zalevsky","year":"2007","journal-title":"J. Immunol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C29","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0092-8674(00)81369-0","article-title":"Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice","volume":"87","author":"Mangiarini","year":"1996","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522154447_DDU151C30","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.jneumeth.2005.12.030","article-title":"A sensitive and selective assay of neuronal degeneration in cell culture","volume":"154","author":"Carrier","year":"2006","journal-title":"J. Neurosci. Methods"},{"key":"key\n\t\t\t\t20170522154447_DDU151C31","doi-asserted-by":"crossref","first-page":"7999","DOI":"10.1523\/JNEUROSCI.2675-04.2004","article-title":"Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity","volume":"24","author":"Khoshnan","year":"2004","journal-title":"J. Neurosci."},{"key":"key\n\t\t\t\t20170522154447_DDU151C32","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.neuint.2003.09.010","article-title":"Effects of neuroinflammation on glia-glia gap junctional intercellular communication: a perspective","volume":"45","author":"Kielian","year":"2004","journal-title":"Neurochem. Int."},{"key":"key\n\t\t\t\t20170522154447_DDU151C33","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1742-2094-1-14","article-title":"Microglia and neuroinflammation: a pathological perspective","volume":"1","author":"Streit","year":"2004","journal-title":"J. Neuroinflammation"},{"key":"key\n\t\t\t\t20170522154447_DDU151C34","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/1750-1326-6-71","article-title":"Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction","volume":"6","author":"Giralt","year":"2011","journal-title":"Mol. Neurodegener."},{"key":"key\n\t\t\t\t20170522154447_DDU151C35","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00401-007-0306-6","article-title":"Huntington disease models and human neuropathology: similarities and differences","volume":"115","author":"Vonsattel","year":"2008","journal-title":"Acta Neuropathol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C36","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1083\/jcb.201105010","article-title":"Nuclear translocation of AMPK-alpha1 potentiates striatal neurodegeneration in Huntington's disease","volume":"194","author":"Ju","year":"2011","journal-title":"J. Cell. Biol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C37","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1093\/brain\/awr199","article-title":"Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination","volume":"134","author":"Brambilla","year":"2011","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170522154447_DDU151C38","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.nbd.2009.01.006","article-title":"Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology","volume":"34","author":"McAlpine","year":"2009","journal-title":"Neurobiol. Dis."},{"key":"key\n\t\t\t\t20170522154447_DDU151C39","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1093\/brain\/awr203","article-title":"Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB","volume":"134","author":"Taoufik","year":"2011","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170522154447_DDU151C40","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.nbd.2011.04.015","article-title":"The role of IkappaB kinase complex in the neurobiology of Huntington's disease","volume":"43","author":"Khoshnan","year":"2011","journal-title":"Neurobiol. Dis."},{"key":"key\n\t\t\t\t20170522154447_DDU151C41","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1399-0004.2011.01748.x","article-title":"Impact of Huntington's across the entire disease spectrum: the phases and stages of disease from the patient perspective","volume":"80","author":"Ho","year":"2011","journal-title":"Clin. Genet."},{"key":"key\n\t\t\t\t20170522154447_DDU151C42","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1111\/j.1460-9568.2005.04281.x","article-title":"6-Hydroxydopamine-induced alterations in blood-brain barrier permeability","volume":"22","author":"Carvey","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"key\n\t\t\t\t20170522154447_DDU151C43","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1186\/1742-2094-9-188","article-title":"Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson's disease","volume":"9","author":"Pisani","year":"2012","journal-title":"J. Neuroinflammation"},{"key":"key\n\t\t\t\t20170522154447_DDU151C44","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.1172\/JCI64565","article-title":"Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression","volume":"122","author":"Weiss","year":"2012","journal-title":"J. Clin. Invest."},{"key":"key\n\t\t\t\t20170522154447_DDU151C45","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1523\/JNEUROSCI.4846-11.2012","article-title":"Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease","volume":"32","author":"Kwan","year":"2012","journal-title":"J. Neurosci."},{"key":"key\n\t\t\t\t20170522154447_DDU151C46","doi-asserted-by":"crossref","first-page":"563784","DOI":"10.1155\/2011\/563784","article-title":"Huntington's disease: an immune perspective","volume":"2011","author":"Nayak","year":"2011","journal-title":"Neurol. Res. Int."},{"key":"key\n\t\t\t\t20170522154447_DDU151C47","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.pbb.2010.04.018","article-title":"Pioglitazone ameliorates behavioral, biochemical and cellular alterations in quinolinic acid induced neurotoxicity: possible role of peroxisome proliferator activated receptor-Upsilon (PPARUpsilon) in Huntington's disease","volume":"96","author":"Kalonia","year":"2010","journal-title":"Pharmacol. Biochem. Behav."},{"key":"key\n\t\t\t\t20170522154447_DDU151C48","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.lfs.2011.02.020","article-title":"Suppressing inflammatory cascade by cyclo-oxygenase inhibitors attenuates quinolinic acid induced Huntington's disease-like alterations in rats","volume":"88","author":"Kalonia","year":"2011","journal-title":"Life Sci."},{"key":"key\n\t\t\t\t20170522154447_DDU151C49","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.bbrc.2003.10.191","article-title":"Suppression of cytochrome c release and apoptosis in testes with heat stress by minocycline","volume":"312","author":"Matsuki","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"key\n\t\t\t\t20170522154447_DDU151C50","doi-asserted-by":"crossref","first-page":"19948","DOI":"10.1074\/jbc.M313629200","article-title":"Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria","volume":"279","author":"Wang","year":"2004","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522154447_DDU151C51","doi-asserted-by":"crossref","first-page":"13496","DOI":"10.1073\/pnas.96.23.13496","article-title":"A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window","volume":"96","author":"Yrjanheikki","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522154447_DDU151C52","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/417074a","article-title":"Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice","volume":"417","author":"Zhu","year":"2002","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522154447_DDU151C53","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/80538","article-title":"Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease","volume":"6","author":"Chen","year":"2000","journal-title":"Nat. Med."},{"key":"key\n\t\t\t\t20170522154447_DDU151C54","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1385\/NMM:9:1:47","article-title":"Lack of minocycline efficiency in genetic models of Huntington's disease","volume":"9","author":"Mievis","year":"2007","journal-title":"Neuromol. Med."},{"key":"key\n\t\t\t\t20170522154447_DDU151C55","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.cyto.2008.11.002","article-title":"Inflammatory demyelinating events following treatment with anti-tumor necrosis factor","volume":"45","author":"Fromont","year":"2009","journal-title":"Cytokine"},{"key":"key\n\t\t\t\t20170522154447_DDU151C56","doi-asserted-by":"crossref","first-page":"32869","DOI":"10.1074\/jbc.M311766200","article-title":"Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pathway","volume":"279","author":"Marchetti","year":"2004","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522154447_DDU151C57","doi-asserted-by":"crossref","first-page":"3550","DOI":"10.1074\/jbc.272.6.3550","article-title":"Inhibition of p75 tumor necrosis factor receptor by antisense oligonucleotides increases hypoxic injury and beta-amyloid toxicity in human neuronal cell line","volume":"272","author":"Shen","year":"1997","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522154447_DDU151C58","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1136\/jcp.44.10.849","article-title":"Quantitative Limulus lysate assay for endotoxin and the effect of plasma","volume":"44","author":"Hurley","year":"1991","journal-title":"J. Clin. Pathol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C59","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1523\/JNEUROSCI.0116-08.2008","article-title":"Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5\/RANTES) by astrocytes","volume":"28","author":"Chou","year":"2008","journal-title":"J. Neurosci."},{"key":"key\n\t\t\t\t20170522154447_DDU151C60","doi-asserted-by":"crossref","first-page":"4851","DOI":"10.1093\/hmg\/ddr424","article-title":"Human Pompe disease-induced pluripotent stem cells for pathogenesis modeling, drug testing and disease marker identification","volume":"20","author":"Huang","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522154447_DDU151C61","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1093\/hmg\/ddl481","article-title":"Dysregulation of C\/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease","volume":"16","author":"Chiang","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522154447_DDU151C62","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1476-9255-7-56","article-title":"Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro","volume":"7","author":"Furuya","year":"2010","journal-title":"J. Inflamm. (Lond.)"},{"key":"key\n\t\t\t\t20170522154447_DDU151C63","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1128\/MCB.01434-12","article-title":"Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease","volume":"33","author":"Lin","year":"2013","journal-title":"Mol. Cell. Biol."},{"key":"key\n\t\t\t\t20170522154447_DDU151C64","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1743-0003-7-56","article-title":"Effects of muscle fatigue on gait characteristics under single and dual-task conditions in young and older adults","volume":"7","author":"Granacher","year":"2010","journal-title":"J. Neuroeng. Rehabil."},{"key":"key\n\t\t\t\t20170522154447_DDU151C65","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/ni.1750","article-title":"Immunological synapse formation inhibits, via NF-kappaB and FOXO1, the apoptosis of dendritic cells","volume":"10","author":"Riol-Blanco","year":"2009","journal-title":"Nat. Immunol."}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/23\/16\/4328\/13923617\/ddu151.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T02:03:36Z","timestamp":1565316216000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddu151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,3]]},"references-count":65,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2014,4,3]]},"published-print":{"date-parts":[[2014,8,15]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddu151","relation":{},"ISSN":["1460-2083","0964-6906"],"issn-type":[{"value":"1460-2083","type":"electronic"},{"value":"0964-6906","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4,3]]}}}