{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T03:00:53Z","timestamp":1768100453344,"version":"3.49.0"},"reference-count":75,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,15]]},"DOI":"10.1093\/hmg\/ddu455","type":"journal-article","created":{"date-parts":[[2014,9,10]],"date-time":"2014-09-10T04:39:10Z","timestamp":1410323950000},"page":"582-596","source":"Crossref","is-referenced-by-count":81,"title":["The IRF5\u2013TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share"],"prefix":"10.1093","volume":"24","author":[{"given":"Leah C.","family":"Kottyan","sequence":"first","affiliation":[{"name":"Division of Rheumatology, Center for Autoimmune Genomics and Etiology and"},{"name":"US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin E.","family":"Zoller","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Autoimmune Genomics and Etiology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Bene","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Autoimmune Genomics and Etiology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoming","family":"Lu","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Autoimmune Genomics and Etiology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer A.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew M.","family":"Rupert","sequence":"additional","affiliation":[{"name":"Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher J.","family":"Lessard","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"},{"name":"Department of Pathology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel E.","family":"Vaughn","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Autoimmune Genomics and Etiology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miranda","family":"Marion","sequence":"additional","affiliation":[{"name":"Department of Biostatistical Sciences and Center for Public Health Genomics and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew T.","family":"Weirauch","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Autoimmune Genomics and Etiology and"},{"name":"US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA"},{"name":"Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahram","family":"Namjou","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Autoimmune Genomics and Etiology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Adler","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Astrid","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart","family":"Glenn","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtney G.","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gideon M.","family":"Hirschfield","sequence":"additional","affiliation":[{"name":"NIHR Biomedical Research Unit, University of Birmingham, Birmingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Xie","sequence":"additional","affiliation":[{"name":"Mount Sinai Hospital Samuel Lunenfeld Research Institute, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalina","family":"Coltescu","sequence":"additional","affiliation":[{"name":"Liver Centre, Toronto Western Hospital, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Amos","sequence":"additional","affiliation":[{"name":"Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"He","family":"Li","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"},{"name":"Department of Pathology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Ice","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swapan K.","family":"Nath","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Mariette","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, H\u00f4pitaux Universitaires Paris-Sud, INSERM U1012, Le Kremlin Bic\u00eatre, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Bowman","sequence":"additional","affiliation":[{"name":"Rheumatology Department, University Hospital Birmingham, Birmingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for UK Primary Sj\u00f6gren's Syndrome Registry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen","family":"Rischmueller","sequence":"additional","affiliation":[{"name":"The Queen Elizabeth Hospital, Adelaide, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue","family":"Lester","sequence":"additional","affiliation":[{"name":"The Queen Elizabeth Hospital, Adelaide, Australia"},{"name":"The University of Adelaide, Adelaide, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan G.","family":"Brun","sequence":"additional","affiliation":[{"name":"Institute of Internal Medicine, University of Bergen, Bergen, Norway"},{"name":"Department of Rheumatology, Haukeland University Hospital, Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lasse G.","family":"G\u00f8ransson","sequence":"additional","affiliation":[{"name":"Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erna","family":"Harboe","sequence":"additional","affiliation":[{"name":"Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roald","family":"Omdal","sequence":"additional","affiliation":[{"name":"Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah S.","family":"Cunninghame-Graham","sequence":"additional","affiliation":[{"name":"Department of Medical and Molecular Genetics, King's College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Vyse","sequence":"additional","affiliation":[{"name":"Department of Medical and Molecular Genetics, King's College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinne","family":"Miceli-Richard","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, H\u00f4pitaux Universitaires Paris-Sud, INSERM U1012, Le Kremlin Bic\u00eatre, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael T.","family":"Brennan","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James A.","family":"Lessard","sequence":"additional","affiliation":[{"name":"Valley Bone and Joint Clinic, Grand Forks, ND, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Wahren-Herlenius","sequence":"additional","affiliation":[{"name":"Department of Medicine, Karolinska Institute, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marika","family":"Kvarnstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Medicine, Karolinska Institute, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabor G.","family":"Illei","sequence":"additional","affiliation":[{"name":"National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torsten","family":"Witte","sequence":"additional","affiliation":[{"name":"Hannover Medical School, Hanover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Jonsson","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Haukeland University Hospital, Bergen, Norway"},{"name":"Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per","family":"Eriksson","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Clinical and Experimental Medicine, Faculty of Health Sciences, Link\u00f6ping University, Link\u00f6ping, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnel","family":"Nordmark","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Rheumatology, Uppsala University, Uppsala, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan-Fai","family":"Ng","sequence":"additional","affiliation":[{"name":"Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for UK Primary Sj\u00f6gren's Syndrome Registry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan-Manuel","family":"Anaya","sequence":"additional","affiliation":[{"name":"Center for Autoimmune Diseases Research (CREA), Universidad del Rosario, Bogot\u00e1, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelson L.","family":"Rhodus","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, University of Minnesota School of Dentistry, Minneapolis, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara M.","family":"Segal","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, University of Minnesota Medical School, Minneapolis, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan T.","family":"Merrill","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith A.","family":"James","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"},{"name":"Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel M.","family":"Guthridge","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Hal Scofield","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"},{"name":"Division of Veterans Affairs Medical Center, Oklahoma City, OK, USA"},{"name":"Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Alarcon-Riquelme","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"},{"name":"de Gen\u00f3mica e Investigaci\u00f3n Oncol\u00f3gica (GENYO), Pfizer-Universidad de Granada\u2013Junta de Andalucia, Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-Cheol","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan A.","family":"Boackle","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsey A.","family":"Criswell","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Rosalind Russell Medical Research Center for Arthritis, University of California San Francisco, San Francisco, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary","family":"Gilkeson","sequence":"additional","affiliation":[{"name":"Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane L.","family":"Kamen","sequence":"additional","affiliation":[{"name":"Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaim O.","family":"Jacob","sequence":"additional","affiliation":[{"name":"Divison of Gastrointestinal and Liver Diseases, Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Kimberly","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Edberg","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciela S.","family":"Alarc\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John D.","family":"Reveille","sequence":"additional","affiliation":[{"name":"Division of Rheumatology and Clinical Immunogenetics, The Univeristy of Texas Health Science Center at Houston, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis M.","family":"Vil\u00e1","sequence":"additional","affiliation":[{"name":"University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Petri","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Johns Hopkins, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosalind","family":"Ramsey-Goldman","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry I.","family":"Freedman","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine, Winston-Salem, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Niewold","sequence":"additional","affiliation":[{"name":"Division of Rheumatology and Immunology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne M.","family":"Stevens","sequence":"additional","affiliation":[{"name":"University of Washington and Seattle Children's Hospital, Seattle, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Betty P.","family":"Tsao","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine, University of California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Ying","sequence":"additional","affiliation":[{"name":"MD Anderson Cancer Center, University of Texas, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen D.","family":"Mayes","sequence":"additional","affiliation":[{"name":"MD Anderson Cancer Center, University of Texas, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga Y.","family":"Gorlova","sequence":"additional","affiliation":[{"name":"MD Anderson Cancer Center, University of Texas, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ward","family":"Wakeland","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical School, Dallas, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Radstake","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ezequiel","family":"Martin","sequence":"additional","affiliation":[{"name":"Instituto de Parasitolog\u00eda y Biomedicina L\u00f3pez Neyra Avda, Granada, Spain and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Martin","sequence":"additional","affiliation":[{"name":"Instituto de Parasitolog\u00eda y Biomedicina L\u00f3pez Neyra Avda, Granada, Spain and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Siminovitch","sequence":"additional","affiliation":[{"name":"Mount Sinai Hospital Samuel Lunenfeld Research Institute, Toronto, ON, Canada"},{"name":"Department of Medicine, University of Toronto, Toronto, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathy L.","family":"Moser Sivils","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick M.","family":"Gaffney","sequence":"additional","affiliation":[{"name":"Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl D.","family":"Langefeld","sequence":"additional","affiliation":[{"name":"Department of Biostatistical Sciences and Center for Public Health Genomics and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Harley","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Autoimmune Genomics and Etiology and"},{"name":"US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth M.","family":"Kaufman","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Center for Autoimmune Genomics and Etiology and"},{"name":"US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2014,9,8]]},"reference":[{"key":"key\n\t\t\t\t20180328180552_DDU455C1","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/ng.631","article-title":"Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis","volume":"42","author":"Hirschfield","year":"2010","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/ng.764","article-title":"Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47","volume":"43","author":"Anderson","year":"2011","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C3","doi-asserted-by":"crossref","first-page":"2825","DOI":"10.1093\/hmg\/dds099","article-title":"Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up","volume":"21","author":"Martin","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C4","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/ng.582","article-title":"Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci","volume":"42","author":"Stahl","year":"2010","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C5","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1002\/art.24662","article-title":"The CGGGG insertion\/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjogren's syndrome","volume":"60","author":"Miceli-Richard","year":"2009","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20180328180552_DDU455C6","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1089\/dna.2009.0929","article-title":"Association between IRF-5 polymorphisms and risk of acute coronary syndrome","volume":"29","author":"Fan","year":"2010","journal-title":"DNA Cell Biol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C7","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1136\/jmg.2007.055012","article-title":"Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations","volume":"45","author":"Kristjansdottir","year":"2008","journal-title":"J. Med. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C8","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/gene.2012.18","article-title":"Interferon regulatory factor 5 gene variants and pharmacological and clinical outcome of Interferonb therapy in multiple sclerosis","volume":"13","author":"Vosslamber","year":"2012","journal-title":"Genes Immun."},{"key":"key\n\t\t\t\t20180328180552_DDU455C9","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/1479-5876-10-170","article-title":"IRF5 gene polymorphisms in melanoma","volume":"10","author":"Uccellini","year":"2012","journal-title":"J. Transl. Med."},{"key":"key\n\t\t\t\t20180328180552_DDU455C10","doi-asserted-by":"crossref","first-page":"5209","DOI":"10.1093\/hmg\/dds359","article-title":"Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants","volume":"21","author":"Juran","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C11","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/ng.81","article-title":"Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci","volume":"40","author":"Harley","year":"2008","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C12","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1093\/hmg\/ddl469","article-title":"Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation","volume":"16","author":"Cunninghame Graham","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C13","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1469-1809.2006.00336.x","article-title":"Association of a common interferon regulatory factor 5 (IRF5) variant with increased risk of systemic lupus erythematosus (SLE)","volume":"71","author":"Demirci","year":"2007","journal-title":"Ann. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C14","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/sj.gene.6364407","article-title":"Opposed independent effects and epistasis in the complex association of IRF5 to SLE","volume":"8","author":"Ferreiro-Neira","year":"2007","journal-title":"Genes Immun."},{"key":"key\n\t\t\t\t20180328180552_DDU455C15","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1038\/ng.468","article-title":"A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus","volume":"41","author":"Gateva","year":"2009","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C16","doi-asserted-by":"crossref","first-page":"6758","DOI":"10.1073\/pnas.0701266104","article-title":"Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus","volume":"104","author":"Graham","year":"2007","journal-title":"Proci. USA"},{"key":"key\n\t\t\t\t20180328180552_DDU455C17","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1038\/ng.472","article-title":"Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus","volume":"41","author":"Han","year":"2009","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C18","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/rheumatology\/ker263","article-title":"Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population","volume":"51","author":"Jarvinen","year":"2012","journal-title":"Rheumatology (Oxford)"},{"key":"key\n\t\t\t\t20180328180552_DDU455C19","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1002\/art.23216","article-title":"Association of IRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: support for a crucial role of intron 1 polymorphisms","volume":"58","author":"Kawasaki","year":"2008","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20180328180552_DDU455C20","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/gene.2008.4","article-title":"Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans","volume":"9","author":"Kelly","year":"2008","journal-title":"Genes Immun."},{"key":"key\n\t\t\t\t20180328180552_DDU455C21","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3899\/jrheum.090440","article-title":"Promoter insertion\/deletion in the IRF5 gene is highly associated with susceptibility to systemic lupus erythematosus in distinct populations, but exerts a modest effect on gene expression in peripheral blood mononuclear cells","volume":"37","author":"Lofgren","year":"2010","journal-title":"J. Rheumatol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C22","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1093\/rheumatology\/ker364","article-title":"Interferon regulatory factor 5 gene polymorphism confers risk to several rheumatic diseases and correlates with expression of alternative thymic transcripts","volume":"51","author":"Nordang","year":"2012","journal-title":"Rheumatology (Oxford)"},{"key":"key\n\t\t\t\t20180328180552_DDU455C23","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1111\/j.1440-1797.2010.01327.x","article-title":"Association of IRF5 gene polymorphisms and lupus nephritis in a Chinese population","volume":"15","author":"Qin","year":"2010","journal-title":"Nephrology (Carlton)"},{"key":"key\n\t\t\t\t20180328180552_DDU455C24","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1007\/s00439-007-0367-6","article-title":"Genetic association of IRF5 with SLE in Mexicans: higher frequency of the risk haplotype and its homozygozity than Europeans","volume":"121","author":"Reddy","year":"2007","journal-title":"Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C25","doi-asserted-by":"crossref","first-page":"R32","DOI":"10.1186\/ar2152","article-title":"Replication of the genetic effects of IFN regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population","volume":"9","author":"Shin","year":"2007","journal-title":"Arthritis Res. Ther."},{"key":"key\n\t\t\t\t20180328180552_DDU455C26","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1093\/hmg\/ddm359","article-title":"Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus","volume":"17","author":"Sigurdsson","year":"2008","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C27","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1086\/428480","article-title":"Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus","volume":"76","author":"Sigurdsson","year":"2005","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C28","first-page":"360","article-title":"Association of a haplotype of IRF5 gene with systemic lupus erythematosus in Chinese","volume":"35","author":"Siu","year":"2008","journal-title":"J. Rheumatol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C29","doi-asserted-by":"crossref","first-page":"e1000841","DOI":"10.1371\/journal.pgen.1000841","article-title":"Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus","volume":"6","author":"Yang","year":"2010","journal-title":"PLoS Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C30","doi-asserted-by":"crossref","first-page":"780436","DOI":"10.1155\/2012\/780436","article-title":"Interferon regulatory factor 5 in the pathogenesis of systemic lupus erythematosus","volume":"2012","author":"Cham","year":"2012","journal-title":"Clin. Dev. Immunol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C31","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1002\/eji.201141642","article-title":"Irf5-deficient mice are protected from pristane-induced lupus via increased Th2 cytokines and altered IgG class switching","volume":"42","author":"Feng","year":"2012","journal-title":"Eur. J. Immunol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C32","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/art.30183","article-title":"Interferon regulatory factor 5 is critical for the development of lupus in MRL\/lpr mice","volume":"63","author":"Tada","year":"2011","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20180328180552_DDU455C33","doi-asserted-by":"crossref","first-page":"3741","DOI":"10.4049\/jimmunol.1201162","article-title":"Monocytes from Irf5-\/- mice have an intrinsic defect in their response to pristane-induced lupus","volume":"189","author":"Yang","year":"2012","journal-title":"J. Immunol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C34","doi-asserted-by":"crossref","first-page":"34044","DOI":"10.1074\/jbc.M112.384669","article-title":"Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2)","volume":"287","author":"Larue","year":"2012","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20180328180552_DDU455C35","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1038\/ng.2435","article-title":"Bayesian refinement of association signals for 14 loci in 3 common diseases","volume":"44","author":"Wellcome Trust Case Control Consortium,","year":"2012","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C36","doi-asserted-by":"crossref","first-page":"3008","DOI":"10.1093\/hmg\/ddm259","article-title":"An insertion\u2013deletion polymorphism in the interferon regulatory factor 5 (IRF5) gene confers risk of inflammatory bowel diseases","volume":"16","author":"Dideberg","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C37","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/ng1782","article-title":"A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus","volume":"38","author":"Graham","year":"2006","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C38","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1002\/art.27223","article-title":"Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus","volume":"62","author":"Feng","year":"2010","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20180328180552_DDU455C39","doi-asserted-by":"crossref","first-page":"5348","DOI":"10.4049\/jimmunol.1103319","article-title":"IRF5 risk polymorphisms contribute to interindividual variance in pattern recognition receptor-mediated cytokine secretion in human monocyte-derived cells","volume":"188","author":"Hedl","year":"2012","journal-title":"J. Immunol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C40","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1136\/annrheumdis-2011-200463","article-title":"IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus","volume":"71","author":"Niewold","year":"2012","journal-title":"Ann. Rheum. Dis."},{"key":"key\n\t\t\t\t20180328180552_DDU455C41","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1111\/j.1440-1746.2008.05379.x","article-title":"Primary biliary cirrhosis in Asians: less common than in Europeans, but just as depressing","volume":"23","author":"Farrell","year":"2008","journal-title":"J. Gastroenterol. Hepatol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C42","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.ajhg.2012.08.010","article-title":"Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population","volume":"91","author":"Nakamura","year":"2012","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C43","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1002\/art.23613","article-title":"Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients","volume":"58","author":"Niewold","year":"2008","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20180328180552_DDU455C44","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1136\/ard.2009.118315","article-title":"Association of IRF5 polymorphisms with activation of the interferon alpha pathway","volume":"69","author":"Rullo","year":"2010","journal-title":"Ann. Rheum. Dis."},{"key":"key\n\t\t\t\t20180328180552_DDU455C45","doi-asserted-by":"crossref","first-page":"594056","DOI":"10.1155\/2012\/594056","article-title":"Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions","volume":"2012","author":"Guthridge","year":"2012","journal-title":"J. Biomed. Biotechnol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C46","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1161\/ATVBAHA.108.163733","article-title":"Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction","volume":"28","author":"Malarstig","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"key\n\t\t\t\t20180328180552_DDU455C47","doi-asserted-by":"crossref","first-page":"R80","DOI":"10.1186\/ar3343","article-title":"Cis-regulation of IRF5 expression is unable to fully account for systemic lupus erythematosus association: analysis of multiple experiments with lymphoblastoid cell lines","volume":"13","author":"Alonso-Perez","year":"2011","journal-title":"Arthritis Res. Ther."},{"key":"key\n\t\t\t\t20180328180552_DDU455C48","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1002\/art.22497","article-title":"Structural insertion\/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus","volume":"56","author":"Kozyrev","year":"2007","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20180328180552_DDU455C49","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3109\/08916934.2010.491842","article-title":"Exon 6 variants carried on systemic lupus erythematosus (SLE) risk haplotypes modulate IRF5 function","volume":"44","author":"Wen","year":"2011","journal-title":"Autoimmunity"},{"key":"key\n\t\t\t\t20180328180552_DDU455C50","doi-asserted-by":"crossref","first-page":"R82","DOI":"10.1186\/ar4262","article-title":"Identification of three new cis-regulatory IRF5 polymorphisms: in vitro studies","volume":"15","author":"Alonso-Perez","year":"2013","journal-title":"Arthritis Res. Ther."},{"key":"key\n\t\t\t\t20180328180552_DDU455C51","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1093\/nar\/24.1.238","article-title":"TRANSFAC: a database on transcription factors and their DNA binding sites","volume":"24","author":"Wingender","year":"1996","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20180328180552_DDU455C52","doi-asserted-by":"crossref","first-page":"D91","DOI":"10.1093\/nar\/gkh012","article-title":"JASPAR: an open-access database for eukaryotic transcription factor binding profiles","volume":"32","author":"Sandelin","year":"2004","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t20180328180552_DDU455C53","doi-asserted-by":"crossref","first-page":"D77","DOI":"10.1093\/nar\/gkn660","article-title":"UniPROBE: an online database of protein binding microarray data on protein-DNA interactions","volume":"37","author":"Newburger","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20180328180552_DDU455C54","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.cell.2012.12.009","article-title":"DNA-binding specificities of human transcription factors","volume":"152","author":"Jolma","year":"2013","journal-title":"Cell"},{"key":"key\n\t\t\t\t20180328180552_DDU455C55","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/489045a","article-title":"Presenting ENCODE","volume":"489","author":"Skipper","year":"2012","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180328180552_DDU455C56","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1038\/nature12961","article-title":"The genomic landscape of Neanderthal ancestry in present-day humans","volume":"507","author":"Sankararaman","year":"2014","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180328180552_DDU455C57","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/rheumatology\/keq302","article-title":"The lupus family registry and repository","volume":"50","author":"Rasmussen","year":"2011","journal-title":"Rheumatology (Oxford)"},{"key":"key\n\t\t\t\t20180328180552_DDU455C58","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1002\/art.1780400928","article-title":"Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus","volume":"40","author":"Hochberg","year":"1997","journal-title":"Arthritis Rheum"},{"key":"key\n\t\t\t\t20180328180552_DDU455C59","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1086\/375613","article-title":"Control of confounding of genetic associations in stratified populations","volume":"72","author":"Hoggart","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C60","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ajhg.2010.11.014","article-title":"Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study","volume":"88","author":"Lessard","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C61","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1086\/420855","article-title":"Design and analysis of admixture mapping studies","volume":"74","author":"Hoggart","year":"2004","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C62","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1086\/420856","article-title":"A high-density admixture map for disease gene discovery in African Americans","volume":"74","author":"Smith","year":"2004","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C63","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1046\/j.1469-1809.2000.6420171.x","article-title":"Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations","volume":"64","author":"McKeigue","year":"2000","journal-title":"Ann. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C64","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/ng1847","article-title":"Principal components analysis corrects for stratification in genome-wide association studies","volume":"38","author":"Price","year":"2006","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C65","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1002\/humu.20695","article-title":"A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: utility and applications","volume":"29","author":"Halder","year":"2008","journal-title":"Hum. Mutat."},{"key":"key\n\t\t\t\t20180328180552_DDU455C66","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"Purcell","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C67","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1038\/ng2088","article-title":"A new multipoint method for genome-wide association studies by imputation of genotypes","volume":"39","author":"Marchini","year":"2007","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C68","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.ip71","article-title":"Haploview: visualization and analysis of SNP genotype data","author":"Barrett","year":"2009","journal-title":"Cold Spring Harb. Protoc."},{"key":"key\n\t\t\t\t20180328180552_DDU455C69","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/bioinformatics\/bth457","article-title":"Haploview: analysis and visualization of LD and haplotype maps","volume":"21","author":"Barrett","year":"2005","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t20180328180552_DDU455C70","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.ajhg.2007.09.022","article-title":"Estimating local ancestry in admixed populations","volume":"82","author":"Sankararaman","year":"2008","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C71","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1038\/ng.2792","article-title":"Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome","volume":"45","author":"Lessard","year":"2013","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C72","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/nrg2615","article-title":"Bayesian statistical methods for genetic association studies","volume":"10","author":"Stephens","year":"2009","journal-title":"Nat. Rev. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C73","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.ajhg.2012.02.023","article-title":"Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study","volume":"90","author":"Lessard","year":"2012","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20180328180552_DDU455C74","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/nature09298","article-title":"Integrating common and rare genetic variation in diverse human populations","volume":"467","author":"Altshuler","year":"2010","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180328180552_DDU455C75","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/ng.565","article-title":"Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus","volume":"42","author":"Radstake","year":"2010","journal-title":"Nat. Genet."}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/24\/2\/582\/17262496\/ddu455.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T10:39:33Z","timestamp":1717324773000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article\/24\/2\/582\/2900952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,8]]},"references-count":75,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,9,8]]},"published-print":{"date-parts":[[2015,1,15]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddu455","relation":{},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,8]]}}}