{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T01:35:53Z","timestamp":1774316153959,"version":"3.50.1"},"reference-count":72,"publisher":"Oxford University Press (OUP)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,7,15]]},"DOI":"10.1093\/hmg\/ddv122","type":"journal-article","created":{"date-parts":[[2015,4,10]],"date-time":"2015-04-10T00:32:41Z","timestamp":1428625961000},"page":"3918-3928","source":"Crossref","is-referenced-by-count":38,"title":["Antioxidant and anti-inflammatory agents mitigate pathology in a mouse model of pseudoachondroplasia"],"prefix":"10.1093","volume":"24","author":[{"given":"Karen L.","family":"Posey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francoise","family":"Coustry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alka C.","family":"Veerisetty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph L.","family":"Alcorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline T.","family":"Hecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2015,4,9]]},"reference":[{"key":"key\n\t\t\t\t20170522151022_DDV122C1","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0945-053X(98)90080-4","article-title":"Characterization of cartilage oligomeric matrix protein (COMP) in human normal and pseudoachondroplasia musculoskeletal tissues","volume":"17","author":"Hecht","year":"1998","journal-title":"Matrix Biol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C2","doi-asserted-by":"crossref","first-page":"6132","DOI":"10.1016\/S0021-9258(18)42671-3","article-title":"Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage","volume":"267","author":"Hedbom","year":"1992","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522151022_DDV122C3","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/jor.1100180412","article-title":"Molecular cloning, sequencing, and tissue and developmental expression of mouse cartilage oligomeric matrix protein (COMP)","volume":"18","author":"Fang","year":"2000","journal-title":"J. Orthop. Res."},{"key":"key\n\t\t\t\t20170522151022_DDV122C4","doi-asserted-by":"crossref","first-page":"293","DOI":"10.2353\/ajpath.2007.060530","article-title":"Unique matrix structure in the rough endoplasmic reticulum cisternae of pseudoachondroplasia chondrocytes","volume":"170","author":"Merritt","year":"2007","journal-title":"Am. J. Pathol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C5","doi-asserted-by":"crossref","first-page":"6083","DOI":"10.1074\/jbc.M009512200","article-title":"Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I, II, and IX","volume":"276","author":"Thur","year":"2001","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522151022_DDV122C6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/1529-0131(199901)42:1<39::AID-ANR5>3.0.CO;2-Y","article-title":"Changes in serum cartilage marker levels indicate altered cartilage metabolism in families with the osteoarthritis-related type II collagen gene COL2A1 mutation","volume":"42","author":"Bleasel","year":"1999","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20170522151022_DDV122C7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1136\/ard.53.1.8","article-title":"Release of cartilage oligomeric matrix protein (COMP) into joint fluid after knee injury and in osteoarthritis","volume":"53","author":"Lohmander","year":"1994","journal-title":"Ann. Rheum. Dis."},{"key":"key\n\t\t\t\t20170522151022_DDV122C8","doi-asserted-by":"crossref","first-page":"25294","DOI":"10.1074\/jbc.M403778200","article-title":"Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias","volume":"279","author":"Mann","year":"2004","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522151022_DDV122C9","doi-asserted-by":"crossref","first-page":"11347","DOI":"10.1074\/jbc.M608744200","article-title":"Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation","volume":"282","author":"Xu","year":"2007","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522151022_DDV122C10","doi-asserted-by":"crossref","first-page":"32655","DOI":"10.1074\/jbc.M504778200","article-title":"Cartilage oligomeric matrix protein\/thrombospondin 5 supports chondrocyte attachment through interaction with integrins","volume":"280","author":"Chen","year":"2005","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522151022_DDV122C11","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/ajmg.10234","article-title":"Pseudoachondroplasia and multiple epiphyseal dysplasia: new etiologic developments","volume":"106","author":"Unger","year":"2001","journal-title":"Am. J. Med. Genet."},{"key":"key\n\t\t\t\t20170522151022_DDV122C12","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/(SICI)1096-8628(19960517)63:2<406::AID-AJMG16>3.0.CO;2-O","article-title":"Natural history study of pseudoachondroplasia","volume":"63","author":"McKeand","year":"1996","journal-title":"Am. J. Med. Genet."},{"key":"key\n\t\t\t\t20170522151022_DDV122C13","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.orthres.2003.11.010","article-title":"Chondrocyte cell death and intracellular distribution of COMP and type IX collagen in the pseudoachondroplasia growth plate","volume":"22","author":"Hecht","year":"2004","journal-title":"J. Orthop. Res."},{"key":"key\n\t\t\t\t20170522151022_DDV122C14","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0945-053X(98)90113-5","article-title":"Retention of cartilage oligomeric matrix protein (COMP) and cell death in redifferentiated pseudoachondroplasia chondrocytes","volume":"17","author":"Hecht","year":"1998","journal-title":"Matrix Biol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C15","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1002\/jor.20100","article-title":"Expression of mutant cartilage oligomeric matrix protein in human chondrocytes induces the pseudoachondroplasia phenotype","volume":"24","author":"Merritt","year":"2006","journal-title":"J. Orthop. Res."},{"key":"key\n\t\t\t\t20170522151022_DDV122C16","doi-asserted-by":"crossref","first-page":"869","DOI":"10.2174\/138945008785909293","article-title":"The role of cartilage oligomeric matrix protein (COMP) in skeletal disease","volume":"9","author":"Posey","year":"2008","journal-title":"Curr. Drug Targets"},{"key":"key\n\t\t\t\t20170522151022_DDV122C17","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1002\/(SICI)1096-8628(19981228)80:5<510::AID-AJMG14>3.0.CO;2-F","article-title":"Identification of twelve mutations in cartilage oligomeric matrix protein (COMP) in patients with pseudoachondroplasia","volume":"80","author":"Deere","year":"1998","journal-title":"Am. J. Med. Genet."},{"key":"key\n\t\t\t\t20170522151022_DDV122C18","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/(SICI)1096-8628(19990827)85:5<486::AID-AJMG10>3.0.CO;2-O","article-title":"Identification of nine novel mutations in cartilage oligomeric matrix protein in patients with pseudoachondroplasia and multiple epiphyseal dysplasia","volume":"85","author":"Deere","year":"1999","journal-title":"Am. J. Med. Genet."},{"key":"key\n\t\t\t\t20170522151022_DDV122C19","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.2353\/ajpath.2009.090184","article-title":"An inducible cartilage oligomeric matrix protein mouse model recapitulates human pseudoachondroplasia phenotype","volume":"175","author":"Posey","year":"2009","journal-title":"Am. J. Pathol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C20","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.ajpath.2011.10.035","article-title":"Chop (Ddit3) is essential for D469del-COMP retention and cell death in chondrocytes in an inducible transgenic mouse model of pseudoachondroplasia","volume":"180","author":"Posey","year":"2012","journal-title":"Am. J. Pathol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C21","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1002\/jbmr.2139","article-title":"Chondrocyte-specific pathology during skeletal growth and therapeutics in a murine model of pseudoachondroplasia","volume":"29","author":"Posey","year":"2014","journal-title":"J. Bone Miner. Res."},{"key":"key\n\t\t\t\t20170522151022_DDV122C22","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1089\/ars.2007.1782","article-title":"Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?","volume":"9","author":"Malhotra","year":"2007","journal-title":"Antioxid. Redox. Signal"},{"key":"key\n\t\t\t\t20170522151022_DDV122C23","doi-asserted-by":"crossref","first-page":"259462","DOI":"10.4061\/2011\/259462","article-title":"Endoplasmic reticulum stress-related inflammation and cardiovascular diseases","volume":"2011","author":"Gotoh","year":"2011","journal-title":"Int. J. Inflam."},{"key":"key\n\t\t\t\t20170522151022_DDV122C24","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1742-2094-6-41","article-title":"ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology","volume":"6","author":"Salminen","year":"2009","journal-title":"J. Neuroinflammation"},{"key":"key\n\t\t\t\t20170522151022_DDV122C25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.biocel.2005.09.018","article-title":"Coordination of ER and oxidative stress signaling: the PERK\/Nrf2 signaling pathway","volume":"38","author":"Cullinan","year":"2006","journal-title":"Int. J. Biochem. Cell. Biol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C26","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.cell.2010.02.034","article-title":"Endoplasmic reticulum stress and the inflammatory basis of metabolic disease","volume":"140","author":"Hotamisligil","year":"2010","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522151022_DDV122C27","doi-asserted-by":"crossref","first-page":"18525","DOI":"10.1073\/pnas.0809677105","article-title":"Antioxidants reduce endoplasmic reticulum stress and improve protein secretion","volume":"105","author":"Malhotra","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"key\n\t\t\t\t20170522151022_DDV122C28","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.neuropharm.2005.10.016","article-title":"Diclofenac, a non-steroidal anti-inflammatory drug, suppresses apoptosis induced by endoplasmic reticulum stresses by inhibiting caspase signaling","volume":"50","author":"Yamazaki","year":"2006","journal-title":"Neuropharmacology"},{"key":"key\n\t\t\t\t20170522151022_DDV122C29","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/emmm.201303227","article-title":"Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress","volume":"6","author":"Hosoi","year":"2014","journal-title":"EMBO Mol. Med."},{"key":"key\n\t\t\t\t20170522151022_DDV122C30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuint.2008.09.017","article-title":"Effect of pranoprofen on endoplasmic reticulum stress in the primary cultured glial cells","volume":"54","author":"Hosoi","year":"2009","journal-title":"Neurochem. Int."},{"key":"key\n\t\t\t\t20170522151022_DDV122C31","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s10753-011-9407-4","article-title":"ER stress, p66shc, and p-Akt\/Akt mediate adjuvant-induced inflammation, which is blunted by argirein, a supermolecule and rhein in rats","volume":"35","author":"Cong","year":"2012","journal-title":"Inflammation"},{"key":"key\n\t\t\t\t20170522151022_DDV122C32","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.ajpath.2011.10.033","article-title":"D469del-COMP retention in chondrocytes stimulates caspase-independent necroptosis","volume":"180","author":"Coustry","year":"2012","journal-title":"Am. J. Pathol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C33","doi-asserted-by":"crossref","first-page":"475","DOI":"10.2106\/00004623-197355030-00003","article-title":"Pseudoachondroplastic dwarfism. A rough-surfaced endoplasmic reticulum storage disorder","volume":"55","author":"Cooper","year":"1973","journal-title":"J. Bone Joint Surg."},{"key":"key\n\t\t\t\t20170522151022_DDV122C34","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1002\/ajmg.a.33909","article-title":"Nosology and classification of genetic skeletal disorders: 2010 revision","volume":"155A","author":"Warman","year":"2011","journal-title":"Am. J. Med. Genet. A"},{"key":"key\n\t\t\t\t20170522151022_DDV122C35","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/ng0795-325","article-title":"Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia","volume":"10","author":"Hecht","year":"1995","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522151022_DDV122C36","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.biocel.2004.01.011","article-title":"Role of TSP-5\/COMP in pseudoachondroplasia","volume":"36","author":"Posey","year":"2004","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C37","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.bbrc.2004.09.035","article-title":"High ER stress in beta-cells stimulates intracellular degradation of misfolded insulin","volume":"324","author":"Allen","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"(Suppl 1)","key":"key\n\t\t\t\t20170522151022_DDV122C38","first-page":"S71","article-title":"Grape seed proanthocyanidines and skin cancer prevention: inhibition of oxidative stress and protection of immune system","volume":"52","author":"Katiyar","year":"2008","journal-title":"Mol. Nutr. Food Res."},{"key":"key\n\t\t\t\t20170522151022_DDV122C39","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/978-0-387-46401-5_9","article-title":"Regulation of COX and LOX by curcumin","volume":"595","author":"Rao","year":"2007","journal-title":"Adv. Exp. Med. Biol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C40","doi-asserted-by":"crossref","first-page":"420","DOI":"10.22203\/eCM.v022a31","article-title":"Inhibition of cyclooxygenase-2 impacts chondrocyte hypertrophic differentiation during endochondral ossification","volume":"22","author":"Welting","year":"2011","journal-title":"Eur. Cell. Mater."},{"key":"key\n\t\t\t\t20170522151022_DDV122C41","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1210\/en.2014-1348","article-title":"Prostacyclin regulates bone growth via the Epac\/Rap1 pathway","volume":"156","author":"Hutchison","year":"2015","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170522151022_DDV122C42","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/j.bbadis.2014.10.005","article-title":"The molecular targets of resveratrol","volume":"1852","author":"Kulkarni","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"key\n\t\t\t\t20170522151022_DDV122C43","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.cell.2012.01.017","article-title":"Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases","volume":"148","author":"Park","year":"2012","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522151022_DDV122C44","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1021\/cn400094w","article-title":"Neuroprotective properties and mechanisms of resveratrol in in vitro and in vivo experimental cerebral stroke models","volume":"4","author":"Singh","year":"2013","journal-title":"ACS Chem. Neurosci."},{"key":"key\n\t\t\t\t20170522151022_DDV122C45","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1002\/art.22180","article-title":"Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis","volume":"54","author":"Funk","year":"2006","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20170522151022_DDV122C46","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1046\/j.0306-5251.2001.01476.x","article-title":"Association between aspirin and upper gastrointestinal complications: systematic review of epidemiologic studies","volume":"52","author":"Garcia Rodriguez","year":"2001","journal-title":"Br. J. Clin. Pharmacol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C47","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1097\/00001648-200109000-00018","article-title":"Relative risk of upper gastrointestinal complications among users of acetaminophen and nonsteroidal anti-inflammatory drugs","volume":"12","author":"Garcia Rodriguez","year":"2001","journal-title":"Epidemiology"},{"key":"key\n\t\t\t\t20170522151022_DDV122C48","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1126\/science.275.5297.218","article-title":"Cancer chemopreventive activity of resveratrol, a natural product derived from grapes","volume":"275","author":"Jang","year":"1997","journal-title":"Science"},{"key":"key\n\t\t\t\t20170522151022_DDV122C49","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nature05354","article-title":"Resveratrol improves health and survival of mice on a high-calorie diet","volume":"444","author":"Baur","year":"2006","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522151022_DDV122C50","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/nrd2060","article-title":"Therapeutic potential of resveratrol: the in vivo evidence","volume":"5","author":"Baur","year":"2006","journal-title":"Nat. Rev. Drug Dis."},{"key":"key\n\t\t\t\t20170522151022_DDV122C51","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.cmet.2008.06.011","article-title":"Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span","volume":"8","author":"Pearson","year":"2008","journal-title":"Cell Metab."},{"key":"key\n\t\t\t\t20170522151022_DDV122C52","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.exger.2008.06.013","article-title":"Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart","volume":"43","author":"Barger","year":"2008","journal-title":"Exp. Gerontol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C53","doi-asserted-by":"crossref","first-page":"e2264","DOI":"10.1371\/journal.pone.0002264","article-title":"A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice","volume":"3","author":"Barger","year":"2008","journal-title":"PloS One"},{"key":"key\n\t\t\t\t20170522151022_DDV122C54","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/s00011-004-1341-6","article-title":"Effect of resveratrol in experimental osteoarthritis in rabbits","volume":"54","author":"Elmali","year":"2005","journal-title":"Inflamm. Res."},{"key":"key\n\t\t\t\t20170522151022_DDV122C55","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1007\/s00296-010-1720-y","article-title":"Effect of resveratrol on cartilage protection and apoptosis inhibition in experimental osteoarthritis of rabbit","volume":"32","author":"Wang","year":"2012","journal-title":"Rheumatol. Int."},{"key":"key\n\t\t\t\t20170522151022_DDV122C56","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1002\/mnfr.201100143","article-title":"Resveratrol and health\u2014a comprehensive review of human clinical trials","volume":"55","author":"Smoliga","year":"2011","journal-title":"Mol. Nutr. Food Res."},{"key":"key\n\t\t\t\t20170522151022_DDV122C57","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/bja\/87.1.3","article-title":"Mechanisms of inflammatory pain","volume":"87","author":"Kidd","year":"2001","journal-title":"Br. J. Anaesth."},{"key":"key\n\t\t\t\t20170522151022_DDV122C58","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1097\/01.rhu.0000130684.35729.55","article-title":"Mechanisms of inflammatory pain: therapeutic implications","volume":"10","author":"Mackey","year":"2004","journal-title":"J. Clin. Rheumatol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C59","doi-asserted-by":"crossref","first-page":"3404","DOI":"10.1002\/art.11333","article-title":"Oncostatin M in combination with tumor necrosis factor alpha induces cartilage damage and matrix metalloproteinase expression in vitro and in vivo","volume":"48","author":"Hui","year":"2003","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20170522151022_DDV122C60","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/art.20776","article-title":"Role of interleukin-1 and tumor necrosis factor alpha in matrix degradation of human osteoarthritic cartilage","volume":"52","author":"Kobayashi","year":"2005","journal-title":"Arthritis Rheum."},{"key":"key\n\t\t\t\t20170522151022_DDV122C61","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1053\/joca.1999.0292","article-title":"Tumor necrosis factor alpha can contribute to focal loss of cartilage in osteoarthritis","volume":"8","author":"Westacott","year":"2000","journal-title":"Osteo. Cart."},{"key":"key\n\t\t\t\t20170522151022_DDV122C62","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1096\/fj.07-9574LSF","article-title":"Dose translation from animal to human studies revisited","volume":"22","author":"Reagan-Shaw","year":"2008","journal-title":"FASEB J."},{"key":"key\n\t\t\t\t20170522151022_DDV122C63","doi-asserted-by":"crossref","first-page":"203ra124","DOI":"10.1126\/scitranslmed.3006247","article-title":"Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice","volume":"5","author":"Garcia","year":"2013","journal-title":"Sci. Transl. Med."},{"key":"key\n\t\t\t\t20170522151022_DDV122C64","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S0016-5085(96)70066-5","article-title":"Nonsteroidal anti-inflammatory drug and phospholipid prodrugs: combination therapy with antisecretory agents in rats","volume":"111","author":"Lichtenberger","year":"1996","journal-title":"Gastroenterology"},{"key":"key\n\t\t\t\t20170522151022_DDV122C65","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/0278-2391(92)90276-6","article-title":"Effect of ibuprofen on the healing and remodeling of bone and articular cartilage in the rabbit temporomandibular joint","volume":"50","author":"Obeid","year":"1992","journal-title":"J. Oral Maxillofac. Surg."},{"key":"key\n\t\t\t\t20170522151022_DDV122C66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10753-006-9012-0","article-title":"Effects of resveratrol in inflammatory arthritis","volume":"30","author":"Elmali","year":"2007","journal-title":"Inflammation"},{"key":"key\n\t\t\t\t20170522151022_DDV122C67","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1002\/mnfr.200900392","article-title":"Resveratrol confers resistance against taxol via induction of cell cycle arrest in human cancer cell lines","volume":"54","author":"Mao","year":"2010","journal-title":"Mol. Nutr. Food Res."},{"key":"key\n\t\t\t\t20170522151022_DDV122C68","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.bcp.2007.09.014","article-title":"Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro","volume":"75","author":"Csaki","year":"2008","journal-title":"Biochem. Pharmacol."},{"key":"key\n\t\t\t\t20170522151022_DDV122C69","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/09637480500512872","article-title":"Plant foods in the management of diabetes mellitus: spices as beneficial antidiabetic food adjuncts","volume":"56","author":"Srinivasan","year":"2005","journal-title":"Int. J. Food Sci. Nutr."},{"key":"key\n\t\t\t\t20170522151022_DDV122C70","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/biof.5520180218","article-title":"Effects of Coenzyme Q10 in Huntington's disease and early Parkinson's disease","volume":"18","author":"Beal","year":"2003","journal-title":"Biofactors"},{"key":"key\n\t\t\t\t20170522151022_DDV122C71","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S1734-1140(12)70847-2","article-title":"Prenatal tolerability of acetaminophen and other over-the-counter non-selective cyclooxygenase inhibitors","volume":"64","author":"Burdan","year":"2012","journal-title":"Pharmacol. Rep."},{"key":"key\n\t\t\t\t20170522151022_DDV122C72","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.2353\/ajpath.2008.071094","article-title":"Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen","volume":"172","author":"Posey","year":"2008","journal-title":"Am. J. Pathol."}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/24\/14\/3918\/17261820\/ddv122.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T19:46:08Z","timestamp":1651693568000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddv122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,9]]},"references-count":72,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2015,4,9]]},"published-print":{"date-parts":[[2015,7,15]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddv122","relation":{},"ISSN":["1460-2083","0964-6906"],"issn-type":[{"value":"1460-2083","type":"electronic"},{"value":"0964-6906","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4,9]]}}}