{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:08:23Z","timestamp":1790690903114,"version":"4.1.0"},"reference-count":48,"publisher":"Oxford University Press (OUP)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum. Mol. Genet."],"DOI":"10.1093\/hmg\/ddw389","type":"journal-article","created":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T12:05:48Z","timestamp":1478606748000},"page":"ddw389","source":"Crossref","is-referenced-by-count":24,"title":["Decreased WNT\/\u03b2-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a\/C gene"],"prefix":"10.1093","author":[{"given":"Caroline","family":"Le Dour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coline","family":"Macquart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fusako","family":"Sera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunichi","family":"Homma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele","family":"Bonne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Morrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard J.","family":"Worman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Muchir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,1,9]]},"reference":[{"key":"2017010917351843000_ddw389v1.1","doi-asserted-by":"publisher","DOI":"10.1038\/6799"},{"key":"2017010917351843000_ddw389v1.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199912023412302"},{"key":"2017010917351843000_ddw389v1.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc052632"},{"key":"2017010917351843000_ddw389v1.4","first-page":"848","article-title":"Heart involvement in lamin A\/C related diseases","volume":"99","author":"Ben Yaou","year":"2006","journal-title":"Arch. Mal. Coeur Vaiss"},{"key":"2017010917351843000_ddw389v1.5","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.006346"},{"key":"2017010917351843000_ddw389v1.6","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddi017"},{"key":"2017010917351843000_ddw389v1.7","doi-asserted-by":"publisher","DOI":"10.1172\/JCI29042"},{"key":"2017010917351843000_ddw389v1.8","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/dds265"},{"key":"2017010917351843000_ddw389v1.9","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1427"},{"key":"2017010917351843000_ddw389v1.10","first-page":"314","article-title":"Wnt signaling in stem cells and cancer","volume":"6","author":"Reya","year":"2005","journal-title":"Nature"},{"key":"2017010917351843000_ddw389v1.11","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000093186.22847.4C"},{"key":"2017010917351843000_ddw389v1.12","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvu004"},{"key":"2017010917351843000_ddw389v1.13","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-015-0481-x"},{"key":"2017010917351843000_ddw389v1.14","doi-asserted-by":"publisher","DOI":"10.1536\/jhj.45.1007"},{"key":"2017010917351843000_ddw389v1.15","doi-asserted-by":"publisher","DOI":"10.1038\/nm979"},{"key":"2017010917351843000_ddw389v1.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2003.11.035"},{"key":"2017010917351843000_ddw389v1.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2003.07.004"},{"key":"2017010917351843000_ddw389v1.18","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.7.686"},{"key":"2017010917351843000_ddw389v1.19","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.88.3.333"},{"key":"2017010917351843000_ddw389v1.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2010.08.013"},{"key":"2017010917351843000_ddw389v1.21","doi-asserted-by":"publisher","DOI":"10.1038\/nature01631"},{"key":"2017010917351843000_ddw389v1.22","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601230"},{"key":"2017010917351843000_ddw389v1.23","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-009-0219-8"},{"key":"2017010917351843000_ddw389v1.24","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddu498"},{"key":"2017010917351843000_ddw389v1.25","doi-asserted-by":"publisher","DOI":"10.1038\/ng1294-323"},{"key":"2017010917351843000_ddw389v1.26","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.yexcr.2016.06.008","article-title":"N-terminal nesprin-2 variants regulate \u03b2-catenin signalling","volume":"345","author":"Zhang","year":"2016","journal-title":"Exp. Cell Res"},{"key":"2017010917351843000_ddw389v1.27","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2009.11.006"},{"key":"2017010917351843000_ddw389v1.28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004114"},{"key":"2017010917351843000_ddw389v1.29","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(99)00376-4"},{"key":"2017010917351843000_ddw389v1.30","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1002\/cphy.c140060","article-title":"Wnt signaling in cardiac disease","volume":"5","author":"Hermans","year":"2015","journal-title":"Compr. Physiol"},{"key":"2017010917351843000_ddw389v1.31","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.114.001274"},{"key":"2017010917351843000_ddw389v1.32","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1004708107"},{"key":"2017010917351843000_ddw389v1.33","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1242\/jcs.111.12.1741","article-title":"Identification of connexin43 as a functional target fro Wnt signaling","volume":"111","author":"Van der Heyden","year":"1998","journal-title":"J Cell. Sci"},{"key":"2017010917351843000_ddw389v1.34","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvn133"},{"key":"2017010917351843000_ddw389v1.35","doi-asserted-by":"publisher","DOI":"10.1023\/A:1021154115673"},{"key":"2017010917351843000_ddw389v1.36","doi-asserted-by":"publisher","DOI":"10.1126\/science.252.5009.1173"},{"key":"2017010917351843000_ddw389v1.37","doi-asserted-by":"publisher","DOI":"10.1172\/JCI7798"},{"key":"2017010917351843000_ddw389v1.38","doi-asserted-by":"crossref","unstructured":"Li J. Li C. Liang D. Lv F. Yuan T. The E. Ma X. Wu Y. Zhen L. Xie D. , . (2016) LRP6 acts as a scaffold protein in cardiac gap junction assembly. Nat. Comm., 7.","DOI":"10.1038\/ncomms11775"},{"key":"2017010917351843000_ddw389v1.39","doi-asserted-by":"publisher","DOI":"10.1042\/bst0070459"},{"key":"2017010917351843000_ddw389v1.40","first-page":"479","article-title":"GSK3 inhibitors: development and therapeutic potential","volume":"3","author":"Cohen","year":"2004","journal-title":"Nat. Rev"},{"key":"2017010917351843000_ddw389v1.41","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-5521(00)00025-9"},{"key":"2017010917351843000_ddw389v1.42","doi-asserted-by":"publisher","DOI":"10.1007\/BF02787342"},{"key":"2017010917351843000_ddw389v1.43","first-page":"241","article-title":"Inhibition of extracellular signal-regulated kinase signaling to prevent cardiomyopathy caused by mutation in the gene encoding A-type lamins","volume":"19","author":"Muchir","year":"2009","journal-title":"Hum. Mol. Genet"},{"key":"2017010917351843000_ddw389v1.44","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.970673"},{"key":"2017010917351843000_ddw389v1.45","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvr301"},{"key":"2017010917351843000_ddw389v1.46","doi-asserted-by":"crossref","first-page":"144ra102.","DOI":"10.1126\/scitranslmed.3003875","article-title":"Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A\/C gene mutation","volume":"4","author":"Choi","year":"2012","journal-title":"Sc. Transl. Med"},{"key":"2017010917351843000_ddw389v1.47","first-page":"ddw090.","article-title":"ERK1\/2 directly acts on CTGF\/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A\/C gene","volume":"pii","author":"Chatzifrangkeskou","year":"2016","journal-title":"Hum. Mol. Genet"},{"key":"2017010917351843000_ddw389v1.48","first-page":"632","article-title":"Pharmacological inhibition of c-Jun N-terminal kinase signaling prevents cardiomyopathy caused by mutation in LMNA gene","volume":"1802","author":"Wu","year":"2016","journal-title":"Bioch. Biophys. Acta"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/26\/2\/333\/10935466\/ddw389.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T20:15:15Z","timestamp":1657656915000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddw389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,9]]},"references-count":48,"alternative-id":["10.1093\/hmg\/ddw389"],"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddw389","relation":{},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,9]]}}}