{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T04:17:32Z","timestamp":1791778652232,"version":"4.3.4"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:00:00Z","timestamp":1516320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["109915\/Z\/15\/Z"],"award-info":[{"award-number":["109915\/Z\/15\/Z"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wellcome Centre for Mitochondrial Research","award":["203105\/Z\/16\/Z"],"award-info":[{"award-number":["203105\/Z\/16\/Z"]}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/N025431\/1"],"award-info":[{"award-number":["MR\/N025431\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"European Research Council","doi-asserted-by":"publisher","award":["309548"],"award-info":[{"award-number":["309548"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wellcome Trust Pathfinder Scheme","award":["201064\/Z\/16\/Z"],"award-info":[{"award-number":["201064\/Z\/16\/Z"]}]},{"DOI":"10.13039\/100010897","name":"Newton Fund","doi-asserted-by":"publisher","award":["MR\/N027302\/1"],"award-info":[{"award-number":["MR\/N027302\/1"]}],"id":[{"id":"10.13039\/100010897","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"European Union Seventh Framework Programme","doi-asserted-by":"publisher","award":["FP7\/2007-2013, 305444 RD-Connect and 305121 Neuromics"],"award-info":[{"award-number":["FP7\/2007-2013, 305444 RD-Connect and 305121 Neuromics"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wellcome Trust Senior Fellow in Clinical Science","award":["101876\/Z\/13\/Z"],"award-info":[{"award-number":["101876\/Z\/13\/Z"]}]},{"DOI":"10.13039\/100006662","name":"NIHR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006662","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Medical Research Council Mitochondrial Biology Unit","award":["MC_UP_1501\/2"],"award-info":[{"award-number":["MC_UP_1501\/2"]}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006662","name":"NIHR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006662","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014461","name":"Biomedical Research Centre","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100014461","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Cambridge University Hospitals NHS Foundation Trust"},{"DOI":"10.13039\/501100000735","name":"University of Cambridge","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Centre for Translational Muscle Disease","award":["G0601943"],"award-info":[{"award-number":["G0601943"]}]},{"DOI":"10.13039\/501100002850","name":"FONDECYT","doi-asserted-by":"publisher","award":["1150677"],"award-info":[{"award-number":["1150677"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,1]]},"DOI":"10.1093\/hmg\/ddy033","type":"journal-article","created":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T00:17:51Z","timestamp":1516234671000},"page":"1186-1195","source":"Crossref","is-referenced-by-count":65,"title":["A novel mechanism causing imbalance of mitochondrial fusion and fission in human myopathies"],"prefix":"10.1093","volume":"27","author":[{"given":"Marina","family":"Bartsakoulia","sequence":"first","affiliation":[{"name":"Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Pyle","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Troncoso-Chand\u00eda","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, School of Biological Sciences, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josefa","family":"Vial-Brizzi","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, School of Biological Sciences, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marysol V","family":"Paz-Fiblas","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, School of Biological Sciences, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Duff","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Griffin","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"Boczonadi","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanns","family":"Lochm\u00fcller","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Kleinle","sequence":"additional","affiliation":[{"name":"Medical Genetics Center, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick F","family":"Chinnery","sequence":"additional","affiliation":[{"name":"MRC Mitochondrial Biology Unit & Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Gr\u00fcnert","sequence":"additional","affiliation":[{"name":"Department of General Pediatrics, Adolescent Medicine and Neonatology, Medical Center \u2013 University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janbernd","family":"Kirschner","sequence":"additional","affiliation":[{"name":"Department of Neuropediatrics and Muscle Disorders, Faculty of Medicine, Medical Center \u2013 University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ver\u00f3nica","family":"Eisner","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, School of Biological Sciences, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Horvath","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,1,19]]},"reference":[{"key":"key\n\t\t\t\t20180328170536_ddy033-B1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1042\/bse0470115","article-title":"Roles of mitochondria in human disease","volume":"47","author":"Duchen","year":"2010","journal-title":"Essays Biochem"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B2","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1038\/nrm3013","article-title":"Mitochondrial fusion and fission in cell life and death","volume":"11","author":"Westermann","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B3","doi-asserted-by":"crossref","first-page":"2965","DOI":"10.1242\/jcs.093609","article-title":"Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle - pivotal roles in Ca2+ and reactive oxygen species signaling","volume":"126","author":"Eisner","year":"2013","journal-title":"J. Cell Sci"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B4","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1093\/brain\/awq007","article-title":"Multi-system neurological disease is common in patients with OPA1 mutations","volume":"133","author":"Yu-Wai-Man","year":"2010","journal-title":"Brain"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B5","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1001\/archneurol.2010.228","article-title":"Defective mitochondrial adenosine triphosphate production in skeletal muscle from patients with dominant optic atrophy due to OPA1 mutations","volume":"68","author":"Lodi","year":"2011","journal-title":"Arch. Neurol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B6","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/ng1341","article-title":"Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A","volume":"36","author":"Z\u00fcchner","year":"2004","journal-title":"Nat. Genet"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B7","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1001\/archneurol.2009.284","article-title":"Genotype-phenotype correlations in Charcot-Marie-Tooth disease type 2 caused by mitofusin 2 mutations","volume":"66","author":"Calvo","year":"2009","journal-title":"Arch. Neurol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B8","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1097\/NEN.0b013e3182764d47","article-title":"Mitochondria and peripheral neuropathies","volume":"71","author":"Vital","year":"2012","journal-title":"J. Neuropathol. Exp. Neurol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B9","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1091\/mbc.12.8.2245","article-title":"Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells","volume":"12","author":"Smirnova","year":"2001","journal-title":"Mol. Biol. Cell"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B10","doi-asserted-by":"crossref","first-page":"21583","DOI":"10.1074\/jbc.C700083200","article-title":"Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology","volume":"282","author":"Chang","year":"2007","journal-title":"J. Biol. Chem"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B11","doi-asserted-by":"crossref","first-page":"35967","DOI":"10.1074\/jbc.M404105200","article-title":"Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1","volume":"279","author":"Zhu","year":"2004","journal-title":"J. Biol. Chem"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B12","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1083\/jcb.200506078","article-title":"Dnm1 forms spirals that are structurally tailored to fit mitochondria","volume":"170","author":"Ingerman","year":"2005","journal-title":"J. Cell Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B13","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/nsmb.1949","article-title":"Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission","volume":"18","author":"Mears","year":"2011","journal-title":"Nat. Struct. Mol. Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B14","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1083\/jcb.201508099","article-title":"Drp1-dependent mitochondrial fission via MiD49\/51 is essential for apoptotic cristae remodeling","volume":"212","author":"Otera","year":"2016","journal-title":"J. Cell Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B15","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1091\/mbc.E12-10-0721","article-title":"Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission","volume":"24","author":"Loson","year":"2013","journal-title":"Mol. Biol. Cell"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B16","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/embor.2011.54","article-title":"MiD49 and MiD51, new components of the mitochondrial fission machinery","volume":"12","author":"Palmer","year":"2011","journal-title":"EMBO Rep"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B17","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1016\/j.yexcr.2013.07.010","article-title":"The mitochondrial elongation factors MIEF1 and MIEF2 exert partially distinct functions in mitochondrial dynamics","volume":"319","author":"Liu","year":"2013","journal-title":"Exp. Cell Res"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B18","doi-asserted-by":"crossref","first-page":"27584","DOI":"10.1074\/jbc.M113.479873","article-title":"Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission","volume":"288","author":"Palmer","year":"2013","journal-title":"J. Biol. Chem"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B19","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1038\/nrm3877","article-title":"Mitochondrial dynamics and inheritance during cell division, development and disease","volume":"15","author":"Mishra","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B20","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1056\/NEJMoa064436","article-title":"A lethal defect of mitochondrial and peroxisomal fission","volume":"356","author":"Waterham","year":"2007","journal-title":"N. Engl. J. Med"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B21","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1038\/ejhg.2015.243","article-title":"DNM1L-related mitochondrial fission defect presenting as refractory epilepsy","volume":"24","author":"Vanstone","year":"2016","journal-title":"Eur. J. Hum. Genet"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B22","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1002\/humu.23033","article-title":"Biallelic mutations in DNM1L are associated with a slowly progressive infantile encephalopathy","volume":"37","author":"Nasca","journal-title":"Hum. Mutat"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B23","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1002\/ajmg.a.37721","article-title":"A novel de novo dominant negative mutation in DNM1L impairs mitochondrial fission and presents as childhood epileptic encephalopathy","volume":"170","author":"Fahrner","year":"2016","journal-title":"Am. J. Med. Genet. A"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B24","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.1093\/brain\/awx219","article-title":"Mutations in DNM1L, as in OPA1, results in dominant optic atrophy despite opposite effects on mitochondrial fusion and fission","volume":"140","author":"Gerber","year":"2017","journal-title":"Brain"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B25","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1136\/jmedgenet-2012-100836","article-title":"Genomic analysis of mitochondrial diseases in a consanguineous population reveals novel candidate disease genes","volume":"49","author":"Shamseldin","year":"2012","journal-title":"J. Med. Genet"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B26","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1136\/jmedgenet-2015-103500","article-title":"Disturbed mitochondrial and peroxisomal dynamics due to loss of MFF causes Leigh-like encephalopathy, optic atrophy and peripheral neuropathy","volume":"53","author":"Koch","year":"2016","journal-title":"J. Med. Genet"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B27","doi-asserted-by":"crossref","first-page":"18792","DOI":"10.1074\/jbc.M400920200","article-title":"Loss of the intermembrane space protein Mgm1\/OPA1 induces swelling and localized constrictions along the lengths of mitochondria","volume":"279","author":"Griparic","year":"2004","journal-title":"J. Biol. Chem"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B28","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1242\/jcs.185165","article-title":"Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission","volume":"129","author":"Osellame","year":"2016","journal-title":"J. Cell Sci"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B29","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.str.2014.01.001","article-title":"The mitochondrial fission receptor MiD51 requires ADP as a cofactor","volume":"22","author":"Loson","year":"2014","journal-title":"Structure"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B30","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1002\/pro.2629","article-title":"Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1","volume":"24","author":"Loson","year":"2015","journal-title":"Protein Sci"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B31","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1083\/jcb.201311014","article-title":"Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission","volume":"204","author":"Richter","year":"2014","journal-title":"J. Cell Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B32","doi-asserted-by":"crossref","first-page":"e219.","DOI":"10.1093\/brain\/aws049","article-title":"MFN2 mutations cause compensatory mitochondrial DNA proliferation","volume":"135","author":"Sitarz","year":"2012","journal-title":"Brain"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B33","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1083\/jcb.201007152","article-title":"Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells","volume":"191","author":"Otera","year":"2010","journal-title":"J. Cell Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B34","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0014-5793(03)00633-1","article-title":"The cristal membrane of mitochondria is the principal site of oxidative phosphorylation","volume":"546","author":"Gilkerson","year":"2003","journal-title":"FEBS Lett"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B35","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0091-679X(06)80004-X","article-title":"Biochemical assays of respiratory chain complex activity","volume":"80","author":"Kirby","year":"2007","journal-title":"Methods Cell Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B36","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/brain\/awu348","article-title":"Exome sequencing in undiagnosed inherited and sporadic ataxias","volume":"138","author":"Pyle","year":"2015","journal-title":"Brain"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B37","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.mito.2012.01.001","article-title":"Microscale oxygraphy reveals OXPHOS impairment in MRC mutant cells","volume":"12","author":"Invernizzi","year":"2012","journal-title":"Mitochondrion"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B38","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1083\/jcb.200309082","article-title":"Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis","volume":"164","author":"Karbowski","year":"2004","journal-title":"J. Cell Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B39","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1083\/jcb.201312066","article-title":"Mitochondrial fusion is frequent in skeletal muscle and supports excitation-contraction coupling","volume":"205","author":"Eisner","year":"2014","journal-title":"J. Cell Biol"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B40","doi-asserted-by":"crossref","first-page":"E859","DOI":"10.1073\/pnas.1617288114","article-title":"Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity","volume":"114","author":"Eisner","year":"2017","journal-title":"Proc. Natl Acad. Sci. U S A"},{"key":"key\n\t\t\t\t20180328170536_ddy033-B41","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.molcel.2010.06.029","article-title":"Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface","volume":"39","author":"Csordas","year":"2010","journal-title":"Mol. Cell"}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/27\/7\/1186\/24398878\/ddy033.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T21:55:58Z","timestamp":1589838958000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article\/27\/7\/1186\/4817577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,19]]},"references-count":41,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2018,1,19]]},"published-print":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddy033","relation":{},"ISSN":["0964-6906","1460-2083"],"issn-type":[{"value":"0964-6906","type":"print"},{"value":"1460-2083","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,4,1]]},"published":{"date-parts":[[2018,1,19]]}}}