{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T14:15:27Z","timestamp":1789222527121,"version":"build-2803163510"},"reference-count":57,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The jujube witches\u2019 broom (JWB) phytoplasma is associated with witches\u2019 broom, dwarfism, and smaller leaves in jujube, resulting in yield losses. In this study, eight putative JWB effector proteins were identified from potential mobile units of the JWB genome. Among them, Zaofeng6 induced witches\u2019 broom symptoms in Arabidopsis and jujube. Zaofeng6-overexpressing Arabidopsis and unrooted jujube transformants displayed witches\u2019 broom-like shoot proliferation. Transient expression of Zaofeng6 induced hypersensitive response like cell death and expression of hypersensitive response marker genes, like harpin-induced gene 1 (H1N1), and the pathogenesis-related genes PR1, PR2, and PR3 in transformed Nicotiana benthamiana leaves, suggesting that Zaofeng6 could be a virulence effector. Yeast two-hybrid library screening and bimolecular fluorescence complementation confirmed that Zaofeng6 interacts with ZjTCP7 through its first two \u03b1-helix domains in the cell nuclei. ZjTCP7 mRNA and protein abundance decreased in Zaofeng6 transgenic jujube seedlings. The expression of some genes in the strigolactone signaling pathway (ZjCCD7, ZjCCD8, and CYP711A1) were down-regulated in jujube shoots overexpressing Zaofeng6 and in zjtcp7 CRISPR\/Cas9 mutants. Zaofeng6 induces shoot proliferation through decreased expression of ZjTCP7 at the transcriptional and translational levels.<\/jats:p>","DOI":"10.1093\/hr\/uhab032","type":"journal-article","created":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T04:46:30Z","timestamp":1642567590000},"source":"Crossref","is-referenced-by-count":44,"title":["Phytoplasma effector Zaofeng6 induces shoot proliferation by decreasing the expression of ZjTCP7 in <i>Ziziphus jujuba<\/i>"],"prefix":"10.1093","volume":"9","author":[{"given":"Peng","family":"Chen","sequence":"first","affiliation":[{"name":"Henan Agricultural University College of Forestry, , 95 Wenhua Road, Zhengzhou 450002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lichuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Henan Agricultural University College of Forestry, , 95 Wenhua Road, Zhengzhou 450002, 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States","volume":"38","author":"Yao","year":"2013","journal-title":"HortScience."},{"key":"2022092909285923000_ref18","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/s41438-020-00346-5","article-title":"The historical and current research progress on jujube\u2014a superfruit for the future","volume":"7","author":"Liu","year":"2020","journal-title":"Hortic Res."},{"key":"2022092909285923000_ref19","first-page":"1","article-title":"The challenges and countermeasures of jujube industry during transition period","volume":"1","author":"Liu","year":"2018","journal-title":"China Fruits."},{"key":"2022092909285923000_ref20","doi-asserted-by":"crossref","first-page":"701","DOI":"10.17660\/ActaHortic.1998.472.94","article-title":"Characterization of the phytoplasmas associated with cherry lethal yellows and jujube witches\u2019-broom diseases in China","volume":"472","author":"Zhu","year":"1998","journal-title":"Acta 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Sin."},{"key":"2022092909285923000_ref25","first-page":"213","article-title":"Effect of jujube witches\u2019 broom (JWB) phytoplasma on the chlorophyll and several protective enzymes in jujube trees","volume":"27","author":"Liu","year":"2012","journal-title":"Acta Agriculturae Boreali Sinica."},{"key":"2022092909285923000_ref26","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.plaphy.2016.04.003","article-title":"Photosynthetic response to phytoplasma infection in Chinese jujube","volume":"105","author":"Liu","year":"2016","journal-title":"Plant Physiol Biochem."},{"key":"2022092909285923000_ref27","doi-asserted-by":"crossref","first-page":"17080","DOI":"10.1038\/hortres.2017.80","article-title":"Combination of iTRAQ proteomics and RNA-seq transcriptomics reveals multiple levels of regulation in phytoplasma-infected Ziziphus jujuba Mill","volume":"4","author":"Ye","year":"2017","journal-title":"Hortic 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expression in response to infection with jujube witches\u2019 broom phytoplasma","volume":"41","author":"Chen","year":"2019","journal-title":"Acta Physiol Plant."},{"key":"2022092909285923000_ref31","article-title":"Genome-wide identification and expression of the lipoxygenase gene family in jujube (Ziziphus jujuba) in response to phytoplasma infection","author":"Li","journal-title":"J Plant Biochem Biotechnol."},{"key":"2022092909285923000_ref32","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.gene.2017.06.044","article-title":"Genome-wide identification and characterization of the SPL gene family in Ziziphus jujuba","volume":"627","author":"Shao","year":"2017","journal-title":"Gene."},{"key":"2022092909285923000_ref33","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1186\/s12864-020-06890-7","article-title":"Genome-wide analysis of the bZIP gene family in Chinese jujube (Ziziphus jujuba 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Beijing","volume":"34","author":"Dai","year":"2019","journal-title":"Journal of Beijing University of Agriculture."},{"key":"2022092909285923000_ref37","first-page":"264","article-title":"Multiplex-PCR for identification of two Hishimonus species (Hemiptera: Cicadellidae) in jujube orchards and detection of jujube witches\u2019 broom (JWB) phytoplasma in their bodies","volume":"58","author":"Hao","year":"2015","journal-title":"Acta Entomol Sin."},{"key":"2022092909285923000_ref38","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/PL00013068","article-title":"A leafhopper (Hishimonus sellatus) transmits phylogenetically distant phytoplasmas: Rhus yellows and Hovenia witches\u2019 broom phytoplasma","volume":"68","author":"Kusunoki","year":"2002","journal-title":"J Gen Plant Pathol."},{"key":"2022092909285923000_ref39","doi-asserted-by":"crossref","DOI":"10.4161\/mge.26145","article-title":"Horizontal transfer of potential mobile units in phytoplasmas","volume":"3","author":"Ku","year":"2013","journal-title":"Mob Genet Elements."},{"key":"2022092909285923000_ref40","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1146\/annurev-arplant-050213-040012","article-title":"Effector-triggered immunity: from pathogen perception to robust defense","volume":"66","author":"Cui","year":"2015","journal-title":"Annu Rev Plant Biol."},{"key":"2022092909285923000_ref41","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1111\/ppa.12786","article-title":"Identification of wheat blue dwarf phytoplasma effectors targeting plant proliferation and defence responses","volume":"67","author":"Wang","year":"2018","journal-title":"Plant Pathol."},{"key":"2022092909285923000_ref42","first-page":"741","article-title":"Multiple pathways regulate shoot branching","volume":"5","author":"Rameau","year":"2014","journal-title":"Front Plant Sci."},{"key":"2022092909285923000_ref43","doi-asserted-by":"crossref","first-page":"7118","DOI":"10.1093\/jxb\/eraa416","article-title":"A CYC\/TB1-type TCP transcription factor controls spikelet meristem identity in barley","volume":"71","author":"Shang","year":"2020","journal-title":"J Exp Bot."},{"key":"2022092909285923000_ref44","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1093\/treephys\/tpy088","article-title":"CRISPR\/Cas9-mediated knockout of Populus BRANCHED1 and BRANCHED2 orthologs reveals a major function in bud outgrowth control","volume":"10","author":"Muhr","year":"2018","journal-title":"Tree Physiol."},{"key":"2022092909285923000_ref45","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s11240-009-9663-2","article-title":"Factors influencing efficiency of shoot regeneration in Ziziphus jujuba Mill. \u2018Huizao\u2019","volume":"101","author":"Feng","year":"2009","journal-title":"Plant Cell Tissue Organ Cult."},{"key":"2022092909285923000_ref46","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/nmeth.1701","article-title":"SignalP 4.0 discriminating signal peptides from transmembrane regions","volume":"8","author":"Petersen","year":"2011","journal-title":"Nat Methods."},{"key":"2022092909285923000_ref47","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1006\/jmbi.2000.4315","article-title":"Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes","volume":"305","author":"Krogh","year":"2001","journal-title":"J Mol Biol."},{"key":"2022092909285923000_ref48","doi-asserted-by":"crossref","first-page":"3682","DOI":"10.1128\/JB.188.10.3682-3696.2006","article-title":"Living with genome in stability: the adaptation of phytoplasmas to diverse environments of their insect and plant hosts","volume":"188","author":"Bai","year":"2006","journal-title":"J Bacteriol."},{"key":"2022092909285923000_ref49","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1046\/j.1365-313x.1998.00343.x","article-title":"Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana","volume":"16","author":"Clough","year":"2010","journal-title":"Plant J."},{"key":"2022092909285923000_ref50","doi-asserted-by":"crossref","first-page":"W242","DOI":"10.1093\/nar\/gky354","article-title":"CRISPOR: intuitive guide selection for CRISPR\/Cas9 genome editing experiments and screens","volume":"W1","author":"Concordet","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"2022092909285923000_ref51","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1111\/j.1365-4632.2006.03082.x","article-title":"Differential expression of Bcl-2, Bax, and CD95 in DNA repair-proficient and DNA repair-deficient basal cell carcinoma patients","volume":"45","author":"Abid","year":"2006","journal-title":"Int J Dermatol."},{"key":"2022092909285923000_ref52","first-page":"185","volume-title":"cDNA Library Protocols (Methods in Molecular Biology)","author":"Cowell","year":"1997"},{"key":"2022092909285923000_ref53","doi-asserted-by":"crossref","first-page":"5315","DOI":"10.1038\/ncomms6315","article-title":"The complex jujube genome provides insights into fruit tree biology","volume":"5","author":"Liu","year":"2014","journal-title":"Nat Commun."},{"key":"2022092909285923000_ref54","first-page":"4293","article-title":"Expression data analysis to identify key target genes in visceral fat tissue associated with obstructive sleep apnea","volume":"19","author":"Chen","year":"2015","journal-title":"Eur Rev Med Pharmacol Sci."},{"key":"2022092909285923000_ref55","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/jxb\/ery349","article-title":"The biosynthesis of phenolic acids is positively regulated by the JA-responsive transcription factor ERF115 in Salvia miltiorrhiza","volume":"70","author":"Sun","year":"2019","journal-title":"J Exp Bot."},{"key":"2022092909285923000_ref56","first-page":"144","article-title":"Ultrasensitive detection of phytoplasmas by nested-PCR assays using two universal primer pairs","volume":"35","author":"Gundersen","year":"1996","journal-title":"Phytopathol Mediterr."},{"key":"2022092909285923000_ref57","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1094\/Phyto-85-728","article-title":"Detection of multiple phytoplasmas in perennial fruit trees with decline symptoms in Italy","volume":"85","author":"Lee","year":"1995","journal-title":"Phytopathology."}],"container-title":["Horticulture 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