{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:36:33Z","timestamp":1789180593861,"version":"build-2803163510"},"reference-count":55,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"High-level Talents from Guangxi University"},{"name":"Innovation Project of Guangxi Graduate Education","award":["YCSW2025080"],"award-info":[{"award-number":["YCSW2025080"]}]},{"DOI":"10.13039\/100032576","name":"State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources","doi-asserted-by":"crossref","award":["SKLCUSA2024-a04"],"award-info":[{"award-number":["SKLCUSA2024-a04"]}],"id":[{"id":"10.13039\/100032576","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100032576","name":"State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources","doi-asserted-by":"crossref","award":["SKLCUSA-a202306"],"award-info":[{"award-number":["SKLCUSA-a202306"]}],"id":[{"id":"10.13039\/100032576","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Guangxi Science and Technology Major Program","award":["guikeAA23062085"],"award-info":[{"award-number":["guikeAA23062085"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270712"],"award-info":[{"award-number":["32270712"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Passion fruit (Passiflora edulis) production is significantly limited by sporadic cold stress events in unfavorable years. The existence of cultivars with varying cold tolerance offers opportunities for genetic improvement of this high-value crop. To elucidate the molecular basis of cold adaption in passion fruit, we conducted an integrated transcriptomic and metabolomic analysis comparing cold-tolerant and cold-sensitive passion fruit cultivars under low-temperature stress. Our multi-omics approach revealed that cold tolerance is associated with significant reprogramming of key pathways, particularly sphingolipid metabolism, phenylpropanoid metabolism, and terpene metabolism. We further validated that exogenous application of the key metabolites within these pathways, sphinganine, chlorogenic acid (CGA), rutin, and three terpenoids enhanced cold tolerance in cold-sensitive cultivars. Conversely, virus-induced gene silencing (VIGS) of core biosynthetic genes (e.g. PesSPT, PesKDSR, PesHCT, and PesFG2) in these pathways compromised cold resistance, leading to increased oxidative damage and more severe phenotypic injury. This study provides comprehensive insights into the molecular networks underlying cold tolerance in passion fruit, highlighting potential candidate genes and metabolites. Our findings establish a crucial foundation for future molecular breeding strategies aimed at improving cold resistance in this profitable horticultural crop.<\/jats:p>","DOI":"10.1093\/hr\/uhag164","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T09:02:21Z","timestamp":1777280541000},"source":"Crossref","is-referenced-by-count":1,"title":["Integrated transcriptomic and metabolomic analysis reveals key pathways and metabolites underlying cold tolerance in passion fruit"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2640-4749","authenticated-orcid":false,"given":"Lin-Hua","family":"Chen","sequence":"first","affiliation":[{"name":"State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University , Nanning 530004 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiong","family":"Dong","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University , Nanning 530004 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing-Liang","family":"Fan","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University , Nanning 530004 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingrong","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University , Nanning 530004 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongcai","family":"Huang","sequence":"additional","affiliation":[{"name":"Crop Genetic Improvement and Biotechnology Laboratory, Guangxi Academy of Agricultural Sciences , Nanning 530007 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3158-2990","authenticated-orcid":false,"given":"Liu","family":"Yang","sequence":"additional","affiliation":[{"name":"Crop Genetic Improvement and Biotechnology Laboratory, Guangxi Academy of Agricultural Sciences , Nanning 530007 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Guo","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University , Nanning 530004 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7197-5070","authenticated-orcid":false,"given":"Wenguo","family":"Cai","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University , Nanning 530004 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3005-526X","authenticated-orcid":false,"given":"Ling-Ling","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University , Nanning 530004 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,27]]},"reference":[{"key":"2026082812263744700_ref1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1080\/23328940.2017.1377812","article-title":"Rapid responses of plants to temperature changes","volume":"4","author":"Nievola","year":"2017","journal-title":"Temperature (Austin)"},{"key":"2026082812263744700_ref2","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1469-8137.2010.03461.x","article-title":"What is stress? Concepts, definitions and applications in seed science","volume":"188","author":"Kranner","year":"2010","journal-title":"New Phytol"},{"key":"2026082812263744700_ref3","doi-asserted-by":"crossref","first-page":"9471","DOI":"10.15446\/rfnam.v74n2.91828","article-title":"Review on the ecophysiology of important Andean fruits: Passiflora L","volume":"74","author":"Fischer","year":"2021","journal-title":"Rev Fac Nac Agron Medell\u00edn"},{"key":"2026082812263744700_ref4","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0304-4238(87)90051-3","article-title":"Effect of temperature on growth, flowering and nutrient uptake of three passionfruit cultivars under low irradiance","volume":"31","author":"Menzel","year":"1987","journal-title":"Sci Hortic"},{"key":"2026082812263744700_ref5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.plantsci.2010.06.019","article-title":"The CBFs: three arabidopsis transcription factors to cold acclimate","volume":"180","author":"Medina","year":"2011","journal-title":"Plant Sci"},{"key":"2026082812263744700_ref6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/pcp\/pci230","article-title":"Functional analysis of rice DREB1\/CBF-type transcription factors involved in cold-responsive gene expression in transgenic rice","volume":"47","author":"Ito","year":"2006","journal-title":"Plant Cell Physiol"},{"key":"2026082812263744700_ref7","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.3390\/ijms23031549","article-title":"ICE-CBF-COR signaling cascade and its regulation in plants responding to cold stress","volume":"23","author":"Hwarari","year":"2022","journal-title":"Int J Mol Sci"},{"key":"2026082812263744700_ref8","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/pcp\/pcu115","article-title":"Cold signal transduction and its interplay with phytohormones during cold acclimation","volume":"56","author":"Shi","year":"2015","journal-title":"Plant Cell Physiol"},{"key":"2026082812263744700_ref9","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/jipb.12918","article-title":"The transcription factor ICE1 functions in cold stress response by binding to the promoters of CBF and COR genes","volume":"62","author":"Tang","year":"2020","journal-title":"J Integr Plant Biol"},{"key":"2026082812263744700_ref10","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/tpj.16226","article-title":"Overexpression of the FERONIA receptor kinase MdMRLK2 enhances apple cold tolerance","volume":"115","author":"Jing","year":"2023","journal-title":"Plant J"},{"key":"2026082812263744700_ref11","article-title":"A TaSnRK1\u03b1 modulates TaPAP6L-mediated wheat cold tolerance through regulating endogenous jasmonic acid","volume":"10","author":"Zhang","year":"2023","journal-title":"Adv Sci (Weinh)"},{"key":"2026082812263744700_ref12","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.108329","article-title":"Comprehensive characterization and expression analysis of enzymatic antioxidant gene families in passion fruit (Passiflora edulis)","volume":"26","author":"Liang","year":"2023","journal-title":"iScience"},{"key":"2026082812263744700_ref13","first-page":"771","article-title":"Effects of low temperature stress on physiological indexes of cold resistance of Passiflora edulis","volume":"51","author":"Dong","year":"2015","journal-title":"Plant Physiol J"},{"key":"2026082812263744700_ref14","doi-asserted-by":"crossref","first-page":"435","DOI":"10.3390\/f8110435","article-title":"De novo transcriptome sequencing in Passiflora edulis Sims to identify genes and signaling pathways involved in cold tolerance","volume":"8","author":"Liu","year":"2017","journal-title":"Forests"},{"key":"2026082812263744700_ref15","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.10977","article-title":"Comparative transcriptomic analysis reveals the cold acclimation during chilling stress in sensitive and resistant passion fruit (Passiflora edulis) cultivars","volume":"9","author":"Wu","year":"2021","journal-title":"PeerJ"},{"key":"2026082812263744700_ref16","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/s12870-019-1797-8","article-title":"Exploring the adaptive mechanism of Passiflora edulis in karst areas via an integrative analysis of nutrient elements and transcriptional profiles","volume":"19","author":"Xu","year":"2019","journal-title":"BMC Plant Biol"},{"key":"2026082812263744700_ref17","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1093\/plphys\/kiad640","article-title":"Integrative multiomics profiling of passion fruit reveals the genetic basis for fruit color and aroma","volume":"194","author":"Zheng","year":"2024","journal-title":"Plant Physiol"},{"key":"2026082812263744700_ref18","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1038\/nprot.2011.335","article-title":"Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry","volume":"6","author":"Dunn","year":"2011","journal-title":"Nat Protoc"},{"key":"2026082812263744700_ref19","doi-asserted-by":"crossref","first-page":"10038","DOI":"10.1021\/ac9019522","article-title":"FiehnLib: mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography\/mass spectrometry","volume":"81","author":"Kind","year":"2009","journal-title":"Anal Chem"},{"key":"2026082812263744700_ref20","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/nmeth.4512","article-title":"Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics","volume":"15","author":"Lai","year":"2018","journal-title":"Nat Methods"},{"key":"2026082812263744700_ref21","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1038\/nprot.2010.50","article-title":"Global metabolic profiling procedures for urine using UPLC-MS","volume":"5","author":"Want","year":"2010","journal-title":"Nat Protoc"},{"key":"2026082812263744700_ref22","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1093\/plphys\/kiae327","article-title":"Transcriptome and metabolome atlas reveals contributions of sphingosine and chlorogenic acid to cold tolerance in Citrus","volume":"196","author":"Xiao","year":"2024","journal-title":"Plant Physiol"},{"key":"2026082812263744700_ref23","first-page":"315","article-title":"Physiological regulation of exogenous chlorogenic acid on chilling tolerance of tomato seedlings","volume":"30","author":"Li","year":"2024","journal-title":"J Plant Nutr Fertil"},{"key":"2026082812263744700_ref24","first-page":"2055","article-title":"Chlorogenic acid as a promising tool for mitigating chilling injury: cold tolerance and the ripening effect on tomato fruit (Solanum lycopersicum L.)","volume":"13","author":"Ilea","year":"2024","journal-title":"Plants (Basel)"},{"key":"2026082812263744700_ref25","doi-asserted-by":"crossref","DOI":"10.1016\/j.plaphy.2025.109647","article-title":"Integrated transcriptome and metabolome analysis revealed hub genes and metabolites associated with subzero temperature tolerance following cold acclimation in rapeseed (Brassica rapa L.)","volume":"221","author":"Fahim","year":"2025","journal-title":"Plant Physiol Biochem"},{"key":"2026082812263744700_ref26","doi-asserted-by":"crossref","first-page":"uhae026","DOI":"10.1093\/hr\/uhae026","article-title":"5-Aminolevulinic acid improves cold resistance through regulation of Sl MYB4\/Sl MYB88\u2013Sl GSTU43 module to scavenge reactive oxygen species in tomato","volume":"11","author":"Zhang","year":"2024","journal-title":"Hortic Res"},{"key":"2026082812263744700_ref27","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s12298-017-0430-2","article-title":"Exogenous application of rutin and gallic acid regulate antioxidants and alleviate reactive oxygen generation in Oryza sativa L","volume":"23","author":"Singh","year":"2017","journal-title":"Physiol Mol Biol Plants"},{"key":"2026082812263744700_ref28","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1021\/acs.jafc.1c06915","article-title":"Different phenylalanine pathway responses to cold stress based on metabolomics and transcriptomics in tartary buckwheat landraces","volume":"70","author":"Song","year":"2022","journal-title":"J Agric Food Chem"},{"key":"2026082812263744700_ref29","article-title":"Role of phytohormones in regulating cold stress tolerance: physiological and molecular approaches for developing cold-smart crop plants. Plant","volume":"8","author":"Raza","year":"2023","journal-title":"Stress"},{"key":"2026082812263744700_ref30","doi-asserted-by":"crossref","first-page":"uhae093","DOI":"10.1093\/hr\/uhae093","article-title":"Multi-omic dissection of the cold resistance traits of white water lily","volume":"11","author":"Qiu","year":"2024","journal-title":"Hortic Res"},{"key":"2026082812263744700_ref31","doi-asserted-by":"crossref","first-page":"uhae366","DOI":"10.1093\/hr\/uhae366","article-title":"Flavonoids as key players in cold tolerance: molecular insights and applications in horticultural crops","volume":"12","author":"Li","year":"2025","journal-title":"Hortic Res"},{"key":"2026082812263744700_ref32","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.4161\/psb.21949","article-title":"Role of proline under changing environments: a review","volume":"7","author":"Hayat","year":"2012","journal-title":"Plant Signal Behav"},{"key":"2026082812263744700_ref33","first-page":"424","article-title":"Regulation of proline biosynthesis, degradation, uptake and transport in higher plants: its implications in plant growth and abiotic stress tolerance","volume":"88","author":"Kishor","year":"2005","journal-title":"Curr Sci"},{"key":"2026082812263744700_ref34","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/j.1438-8677.2009.00299.x","article-title":"Cold stress and acclimation \u2013 what is important for metabolic adjustment?","volume":"12","author":"Jansk\u00e1","year":"2010","journal-title":"Plant Biol (Stuttg)"},{"key":"2026082812263744700_ref35","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1365-313X.2012.05064.x","article-title":"Identification of a metabolic bottleneck for cold acclimation in Arabidopsis thaliana","volume":"72","author":"N\u00e4gele","year":"2012","journal-title":"Plant J"},{"key":"2026082812263744700_ref36","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1046\/j.1365-3040.2003.00983.x","article-title":"Altering flux through the sucrose biosynthesis pathway in transgenic Arabidopsis thaliana modifies photosynthetic acclimation at low temperatures and the development of freezing tolerance","volume":"26","author":"Strand","year":"2003","journal-title":"Plant Cell Environ"},{"key":"2026082812263744700_ref37","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1080\/07388551.2022.2053056","article-title":"Cold stress regulates accumulation of flavonoids and terpenoids in plants by phytohormone, transcription process, functional enzyme, and epigenetics","volume":"43","author":"He","year":"2023","journal-title":"Crit Rev Biotechnol"},{"key":"2026082812263744700_ref38","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.3390\/metabo13101094","article-title":"Lipid and amino acid pathway metabolites contribute to cold tolerance in Quercus wutaishanica","volume":"13","author":"Li","year":"2023","journal-title":"Metabolites"},{"key":"2026082812263744700_ref39","doi-asserted-by":"crossref","first-page":"uhae096","DOI":"10.1093\/hr\/uhae096","article-title":"SlGAD2 is the target of SlTHM27, positively regulates cold tolerance by mediating anthocyanin biosynthesis in tomato","volume":"11","author":"Wang","year":"2024","journal-title":"Hortic Res"},{"key":"2026082812263744700_ref40","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2020.101051","article-title":"Towards model-driven characterization and manipulation of plant lipid metabolism","volume":"80","author":"Correa","year":"2020","journal-title":"Prog Lipid Res"},{"key":"2026082812263744700_ref41","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.jgg.2023.07.004","article-title":"Genetic and lipidomic analyses reveal the key role of lipid metabolism for cold tolerance in maize","volume":"51","author":"Gao","year":"2024","journal-title":"J Genet Genomics"},{"key":"2026082812263744700_ref42","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.tplants.2007.07.002","article-title":"Cold stress regulation of gene expression in plants","volume":"12","author":"Chinnusamy","year":"2007","journal-title":"Trends Plant Sci"},{"key":"2026082812263744700_ref43","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1111\/nph.15696","article-title":"Advances and challenges in uncovering cold tolerance regulatory mechanisms in plants","volume":"222","author":"Ding","year":"2019","journal-title":"New Phytol"},{"key":"2026082812263744700_ref44","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1104\/pp.17.01311","article-title":"Transcriptomic insights into phenological development and cold tolerance of wheat grown in the field","volume":"176","author":"Li","year":"2018","journal-title":"Plant Physiol"},{"key":"2026082812263744700_ref45","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1016\/j.molp.2018.10.001","article-title":"Emerging roles of sphingolipid signaling in plant response to biotic and abiotic stresses","volume":"11","author":"Ali","year":"2018","journal-title":"Mol Plant"},{"key":"2026082812263744700_ref46","doi-asserted-by":"crossref","DOI":"10.1016\/j.xplc.2021.100214","article-title":"Sphingolipid metabolism, transport, and functions in plants: recent progress and future perspectives","volume":"2","author":"Liu","year":"2021","journal-title":"Plant Commun"},{"key":"2026082812263744700_ref47","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/plb.13477","article-title":"Suppression of mitochondrial alternative oxidase can result in upregulation of the ROS scavenging network: some possible mechanisms underlying the compensation effect","volume":"25","author":"Garmash","year":"2023","journal-title":"Plant Biol (Stuttg)"},{"key":"2026082812263744700_ref48","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1105\/tpc.18.00168","article-title":"A 5-enolpyruvylshikimate 3-phosphate synthase functions as a transcriptional repressor in Populus","volume":"30","author":"Xie","year":"2018","journal-title":"Plant Cell"},{"key":"2026082812263744700_ref49","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"2026082812263744700_ref50","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"HISAT: a fast spliced aligner with low memory requirements","volume":"12","author":"Kim","year":"2015","journal-title":"Nat Methods"},{"key":"2026082812263744700_ref51","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/nbt.3122","article-title":"StringTie enables improved reconstruction of a transcriptome from RNA-seq reads","volume":"33","author":"Pertea","year":"2015","journal-title":"Nat Biotechnol"},{"key":"2026082812263744700_ref52","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol"},{"key":"2026082812263744700_ref53","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1093\/plcell\/koae039","article-title":"Pan-transcriptomic analysis reveals alternative splicing control of cold tolerance in rice","volume":"36","author":"Zhong","year":"2024","journal-title":"Plant Cell"},{"key":"2026082812263744700_ref54","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1104\/pp.112.210740","article-title":"A basic helix-loop-helix transcription factor, PtrbHLH, of Poncirus trifoliata confers cold tolerance and modulates peroxidase-mediated scavenging of hydrogen peroxide","volume":"162","author":"Huang","year":"2013","journal-title":"Plant Physiol"},{"key":"2026082812263744700_ref55","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1007\/s11033-020-05385-8","article-title":"Identification and evaluation of reference genes for quantitative real-time PCR analysis in Passiflora edulis under stem rot condition","volume":"47","author":"Wu","year":"2020","journal-title":"Mol Biol Rep"}],"container-title":["Horticulture Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/hr\/advance-article-pdf\/doi\/10.1093\/hr\/uhag164\/68164034\/uhag164.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/hr\/article-pdf\/13\/9\/uhag164\/68164034\/uhag164.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/hr\/article-pdf\/13\/9\/uhag164\/68164034\/uhag164.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T16:26:57Z","timestamp":1787934417000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hr\/article\/doi\/10.1093\/hr\/uhag164\/8662925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,27]]},"references-count":55,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/hr\/uhag164","relation":{},"ISSN":["2052-7276"],"issn-type":[{"value":"2052-7276","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,4,27]]},"article-number":"uhag164"}}