{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T15:57:17Z","timestamp":1778169437050,"version":"3.51.4"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T00:00:00Z","timestamp":1551225600000},"content-version":"vor","delay-in-days":57,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,1,1]]},"DOI":"10.1093\/hropen\/hoz003","type":"journal-article","created":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T07:43:02Z","timestamp":1549266182000},"source":"Crossref","is-referenced-by-count":14,"title":["A randomized controlled trial of AMH-based individualized FSH dosing in a GnRH antagonist protocol for IVF"],"prefix":"10.1093","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5619-1809","authenticated-orcid":false,"given":"J","family":"Friis Petersen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, North Zealand Hospital, Dyrehavevej 29, Hilleroed, Denmark"},{"name":"The Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"L\u00f8kkegaard","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, North Zealand Hospital, Dyrehavevej 29, Hilleroed, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L F","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, North Zealand Hospital, Dyrehavevej 29, Hilleroed, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Torp","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, North Zealand Hospital, Dyrehavevej 29, Hilleroed, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Egeberg","sequence":"additional","affiliation":[{"name":"The Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Hedegaard","sequence":"additional","affiliation":[{"name":"The Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Nysom","sequence":"additional","affiliation":[{"name":"The Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Nyboe Andersen","sequence":"additional","affiliation":[{"name":"The Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,2,27]]},"reference":[{"key":"key\n\t\t\t\t2019030108304109000_hoz003C1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.rbmo.2017.01.012","article-title":"A randomized controlled trial investigating the use of a predictive nomogram for the selection of the FSH starting dose in IVF\/ICSI cycles","volume":"34","author":"Allegra","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C2","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1093\/humrep\/des101","article-title":"The value of anti-Mullerian hormone measurement in the long GnRH agonist protocol: association with ovarian response and gonadotrophin-dose adjustments","volume":"27","author":"Anckaert","year":"2012","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C3","doi-asserted-by":"crossref","first-page":"444","DOI":"10.3109\/09513590.2014.892066","article-title":"The rate of high ovarian response in women identified at risk by a high serum AMH level is influenced by the type of gonadotropin","volume":"30","author":"Arce","year":"2014","journal-title":"Gynecol Endocrinol"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C5","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.fertnstert.2016.03.041","article-title":"Efficacy and safety of frozen-thawed embryo transfer in women aged 35 to 42 years from the PURSUE randomized clinical trial","volume":"106","author":"Boostanfar","year":"2016","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C6","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1093\/humrep\/dev150","article-title":"The sub-optimal response to controlled ovarian stimulation: manageable or inevitable?","volume":"30","author":"Broekmans","year":"2015","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C7","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.fertnstert.2007.12.013","article-title":"The role of antimullerian hormone in prediction of outcome after IVF: comparison with the antral follicle count","volume":"91","author":"Broer","year":"2009","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C8","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.jclinepi.2006.01.014","article-title":"Review: a gentle introduction to imputation of missing values","volume":"59","author":"Donders","year":"2006","journal-title":"J Clin Epidemiol"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C9","author":"Evers","year":"2017"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C10","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1093\/humupd\/dmt037","article-title":"Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers: from theory to practice","volume":"20","author":"La Marca","year":"2014","journal-title":"Hum Reprod Update"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C11","first-page":"CD012693","article-title":"Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF\/ICSI)","volume":"2","author":"Lensen","year":"2018","journal-title":"Cochrane database Syst Rev"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C12","doi-asserted-by":"crossref","first-page":"3288","DOI":"10.1210\/jc.2016-1340","article-title":"Baseline AMH level associated with ovulation following ovulation induction in women with polycystic ovary syndrome","volume":"101","author":"Mumford","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C13","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.fertnstert.2014.12.114","article-title":"Comparison of antim\u00fcllerian hormone levels and antral follicle count as predictor of ovarian response to controlled ovarian stimulation in good-prognosis patients at individual fertility clinics in two multicenter trials","volume":"103","author":"Nelson","year":"2015","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C14","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.fertnstert.2015.06.024","article-title":"Two new automated, compared with two enzyme-linked immunosorbent, antim\u00fcllerian hormone assays","volume":"104","author":"Nelson","year":"2015","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C15","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1093\/humrep\/dem204","article-title":"Serum anti-M\u00fcllerian hormone and FSH: prediction of live birth and extremes of response in stimulated cycles\u2014implications for individualization of therapy","volume":"22","author":"Nelson","year":"2007","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C16","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1093\/humrep\/den480","article-title":"Anti-M\u00fcllerian hormone-based approach to controlled ovarian stimulation for assisted conception","volume":"24","author":"Nelson","year":"2009","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C17","doi-asserted-by":"crossref","first-page":"625","DOI":"10.3109\/09513590.2016.1147548","article-title":"Selective use of corifollitropin for controlled ovarian stimulation for IVF in patients with low anti-M\u00fcllerian hormone","volume":"32","author":"Nielsen","year":"2016","journal-title":"Gynecol Endocrinol"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C18","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.fertnstert.2016.10.033","article-title":"Individualized versus conventional ovarian stimulation for in vitro fertilization: a multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial","volume":"107","author":"Nyboe Andersen","year":"2017","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C19","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.rbmo.2014.11.013","article-title":"Randomized, controlled, open-label, non-inferiority study of the CONSORT algorithm for individualized dosing of follitropin alfa","volume":"30","author":"Olivennes","year":"2015","journal-title":"Reprod Biomed Online"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C20","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1093\/humrep\/dex319","article-title":"Individualized versus standard FSH dosing in women starting IVF\/ICSI: an RCT. Part 2: The predicted hyper responder","volume":"32","author":"Oudshoorn","year":"2017","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C21","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1093\/humrep\/14.3.622","article-title":"A prospective, randomized, double-blind clinical trial to study the efficacy and efficiency of a fixed dose of recombinant follicle stimulating hormone (Puregon) in women undergoing ovarian stimulation","volume":"14","author":"Out","year":"1999","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C22","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1093\/humrep\/deg472","article-title":"A prospective randomized clinical trial comparing an individual dose of recombinant FSH based on predictive factors versus a \u2018standard\u2019 dose of 150 IU\/day in \u2018standard\u2019 patients undergoing IVF\/ICSI treatment","volume":"18","author":"Popovic-Todorovic","year":"2003","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C23","doi-asserted-by":"crossref","first-page":"e016106","DOI":"10.1136\/bmjopen-2017-016106","article-title":"Comparison of a \u2018freeze-all\u2019 strategy including GnRH agonist trigger versus a \u2018fresh transfer\u2019 strategy including hCG trigger in assisted reproductive technology (ART): a study protocol for a randomised controlled trial","volume":"7","author":"Stormlund","year":"2017","journal-title":"BMJ Open"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C24","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1093\/humrep\/dew051","article-title":"Risk of severe ovarian hyperstimulation syndrome in GnRH antagonist versus GnRH agonist protocol: RCT including 1050 first IVF\/ICSI cycles","volume":"31","author":"Toftager","year":"2016","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C25","first-page":"556","article-title":"Cumulative live birth rates after one ART cycle including all subsequent frozen-thaw cycles in 1050 women: secondary outcome of an RCT comparing GnRH-antagonist and GnRH-agonist protocols","volume":"32","author":"Toftager","year":"2017","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C26","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1093\/humrep\/dex321","article-title":"Individualized FSH dosing based on ovarian reserve testing in women starting IVF\/ICSI: a multicentre trial and cost-effectiveness analysis","volume":"32","author":"van Tilborg","year":"2017","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C27","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.1093\/humrep\/dex318","article-title":"Individualized versus standard FSH dosing in women starting IVF\/ICSI: an RCT. Part 1: The predicted poor responder","volume":"32","author":"van Tilborg","year":"2017","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019030108304109000_hoz003C28","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1093\/humrep\/der182","article-title":"Anti-Mullerian hormone-tailored stimulation protocols improve outcomes whilst reducing adverse effects and costs of IVF","volume":"26","author":"Yates","year":"2011","journal-title":"Hum Reprod"}],"container-title":["Human Reproduction Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hropen\/article-pdf\/2019\/1\/hoz003\/28000548\/hoz003.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T08:30:52Z","timestamp":1551429052000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hropen\/article\/doi\/10.1093\/hropen\/hoz003\/5365630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,1]]},"references-count":27,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,2,27]]},"published-print":{"date-parts":[[2019,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/hropen\/hoz003","relation":{},"ISSN":["2399-3529"],"issn-type":[{"value":"2399-3529","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019]]},"published":{"date-parts":[[2019,1,1]]}}}