{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T07:38:41Z","timestamp":1792741121052,"version":"4.5.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,6]]},"DOI":"10.1093\/humrep\/14.6.1440","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T22:47:51Z","timestamp":1027723671000},"page":"1440-1444","source":"Crossref","is-referenced-by-count":24,"title":["Effect of prednisolone on serum and follicular fluid androgen concentrations in women with polycystic ovary syndrome undergoing in-vitro fertilization"],"prefix":"10.1093","volume":"14","author":[{"given":"Margareta","family":"Fridstro\u0308m","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjell","family":"Carlstro\u0308m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Sjo\u0308blom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torbjo\u0308rn","family":"Hillensjo\u0308","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1999,6]]},"reference":[{"key":"key\n\t\t\t\t20170410032821_ARCURI-ETAL-1996","doi-asserted-by":"crossref","unstructured":"Arcuri, F., Monder, C., Lockwood, C.J. et al. (1996) Expression of 11 beta-hydroxysteroid dehydrogenase during decidualization of human endometrial stromal cells. Endocrinology, 137, 595\u2013600.","DOI":"10.1210\/endo.137.2.8593807"},{"key":"key\n\t\t\t\t20170410032821_BARNES-AND-ROSENFIELD-1989","doi-asserted-by":"crossref","unstructured":"Barnes, R. and Rosenfield, R.L. (1989) Polycystic ovary syndrome: pathogenesis and treatment. Ann. Intern. Med., 110, 386\u2013399.","DOI":"10.7326\/0003-4819-110-5-386"},{"key":"key\n\t\t\t\t20170410032821_BERGH-ETAL-1996","doi-asserted-by":"crossref","unstructured":"Bergh, C., Carlstro\u0308m, K., Selleskog, U. et al. (1996) Effect of growth hormone on follicular fluid androgen levels in patients treated with gonadotropins before in vitro fertilization. Eur. J. Endocrinol., 134, 190\u2013196.","DOI":"10.1530\/eje.0.1340190"},{"key":"key\n\t\t\t\t20170410032821_BIDER-ETAL-1996","doi-asserted-by":"crossref","unstructured":"Bider, D., Amoday, I., Tur-Kaspa, I. et al. (1996) The addition of glucocorticoid to the protocol of programmed oocyte retrieval for in-vitro fertilization\u2014a randomized study. Hum. Reprod., 11, 1606\u20131608.","DOI":"10.1093\/oxfordjournals.humrep.a019454"},{"key":"key\n\t\t\t\t20170410032821_BRODY-ETAL-1983","doi-asserted-by":"crossref","unstructured":"Brody, S., Carlstro\u0308m, K., Lagrelius, A. et al. (1983) Serum levels of 4-androstene-3,17-dione in menstruating and postmenopausal women. Evaluation of a radioimmunoassay and correlation to bone mineral content and endometrial pathology. Acta Obstet. Gynecol. Scand., 62, 531\u2013534.","DOI":"10.3109\/00016348309154231"},{"key":"key\n\t\t\t\t20170410032821_CARLSTROM-ETAL-1988","doi-asserted-by":"crossref","unstructured":"Carlstro\u0308m, K., Brody, S., Lunell, N.O. et al. (1988) Dehydroepiandrosterone sulphate and dehydroepiandrosterone in serum: differences related to age and sex. Maturitas, 10, 297\u2013306.","DOI":"10.1016\/0378-5122(88)90065-5"},{"key":"key\n\t\t\t\t20170410032821_CHANG-ETAL-1983","doi-asserted-by":"crossref","unstructured":"Chang, R.J., Laufer, L.R., Meldrum, D.R. et al. (1983) Steroid secretion in polycystic ovarian disease after ovarian suppression by a long-acting gonadotropin-releasing agonist. J. Clin. Endocrinol. Metab., 56, 897\u2013903.","DOI":"10.1210\/jcem-56-5-897"},{"key":"key\n\t\t\t\t20170410032821_COHEN-ETAL-1990","doi-asserted-by":"crossref","unstructured":"Cohen, J., Malter, H., Elsner, C. et al. (1990) Immunosuppression supports implantation of zona pellucida dissected human embryos. Fertil. Steril., 53, 662\u2013665.","DOI":"10.1016\/S0015-0282(16)53460-8"},{"key":"key\n\t\t\t\t20170410032821_CRILLY-ETAL-1981","doi-asserted-by":"crossref","unstructured":"Crilly, R.G., Francis, R.M. and Nordin, B.E.C. (1981) Steroid hormones, ageing and bone. Clin. Endocrinol. Metab., 10, 115\u2013139.","DOI":"10.1016\/S0300-595X(81)80041-2"},{"key":"key\n\t\t\t\t20170410032821_DALE-ETAL-1992","doi-asserted-by":"crossref","unstructured":"Dale, P.O., Tanbo, T., Djo\u0308seland, O. et al. (1992) Persistence of hyperinsulinemia in polycystic ovary syndrome after ovarian suppression by gonadotropin-releasing hormone agonist. Acta Endocrinol., 126, 132\u2013136.","DOI":"10.1530\/acta.0.1260132"},{"key":"key\n\t\t\t\t20170410032821_DALY-ETAL-1984","doi-asserted-by":"crossref","unstructured":"Daly, D.C., Walters, C.A., Soto-Albors, C.E. et al. (1984) A randomized study of dexamethasone in ovulation induction with clomiphene citrate. Fertil. Steril., 41, 844\u2013848.","DOI":"10.1016\/S0015-0282(16)47896-9"},{"key":"key\n\t\t\t\t20170410032821_DIAMANT-AND-EVRON-1981","doi-asserted-by":"crossref","unstructured":"Diamant, Y.Z. and Evron, S. (1981) Induction of ovulation by combined clomiphene citrate and dexamethasone treatment in clomiphene citrate nonresponders. Eur. J. Obstet. Gynecol. Reprod. Biol., 11, 335\u2013340.","DOI":"10.1016\/0028-2243(81)90034-4"},{"key":"key\n\t\t\t\t20170410032821_DOR-ETAL-1990","doi-asserted-by":"crossref","unstructured":"Dor, J., Schulman, A., Levran, D. et al. (1990) The treatment of patients with polycystic ovary syndrome by in-vitro fertilization and embryo transfer: a comparison of results with those of patients with tubal infertility. Hum. Reprod., 5, 816\u2013818.","DOI":"10.1093\/oxfordjournals.humrep.a137189"},{"key":"key\n\t\t\t\t20170410032821_EHRMANN-ETAL-1995","doi-asserted-by":"crossref","unstructured":"Ehrmann, D.A., Barnes, R.B. and Rosenfield, R.L. (1995) Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion. Endocrine Rev., 16, 322\u2013353.","DOI":"10.1210\/er.16.3.322"},{"key":"key\n\t\t\t\t20170410032821_EVRON-ETAL-1983","doi-asserted-by":"crossref","unstructured":"Evron, S., Navot, D., Laufer, N. et al. (1983) Induction of ovulation with combined human gonadotropins and dexamethasone in women with polycystic ovarian disease. Fertil. Steril., 40, 183\u2013186.","DOI":"10.1016\/S0015-0282(16)47234-1"},{"key":"key\n\t\t\t\t20170410032821_FRANKS-1995","doi-asserted-by":"crossref","unstructured":"Franks, S. (1995) Polycystic ovary syndrome. N. Engl J. Med., 333, 853\u2013861.","DOI":"10.1056\/NEJM199509283331307"},{"key":"key\n\t\t\t\t20170410032821_GILLING-SMITH-ETAL-1994","unstructured":"Gilling-Smith, C., Willis, D., Beard, R. et al. (1994) Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries. J. Clin. Endocrinol. Metab., 79, 1158\u20131165."},{"key":"key\n\t\t\t\t20170410032821_GREENBLATT-ETAL-1956","doi-asserted-by":"crossref","unstructured":"Greenblatt, R.B., Barfield, W. and Lampros, C.P. (1956) Cortisone in the treatment of infertility. Fertil. Steril., 7, 203\u2013212.","DOI":"10.1016\/S0015-0282(16)32340-8"},{"key":"key\n\t\t\t\t20170410032821_HANING-ETAL-1985","doi-asserted-by":"crossref","unstructured":"Haning, R.V., Austin, C.W. and Carlson, I.H. (1985) Role of dehydroepiandrosterone sulfate as prehormone for ovarian steroidogenesis. Obstet. Gynecol., 65, 199\u2013205.","DOI":"10.1097\/00006254-198508000-00016"},{"key":"key\n\t\t\t\t20170410032821_HANING-ETAL-1993","unstructured":"Haning, R.V., Hacket, R.J., Flood, C.A. et al. (1993) Plasma dehydroepiandrosterone sulfate serves as a prehormone for 48% of FF T during treatment with menotrophins. J. Clin. Endocrinol. Metab., 76, 1301\u20131307."},{"key":"key\n\t\t\t\t20170410032821_HILLIER-AND-TETSUKA-1997","doi-asserted-by":"crossref","unstructured":"Hillier, S.G. and Tetsuka, M. (1997) Role of androgens in follicle maturation and atresia. Baillieres Clin. Obstet. Gynecol., 11, 249\u2013260.","DOI":"10.1016\/S0950-3552(97)80036-3"},{"key":"key\n\t\t\t\t20170410032821_HOMBURG-ETAL-1993A","doi-asserted-by":"crossref","unstructured":"Homburg, R., Berkowitz, D., Levy, T. et al. (1993a). In vitro fertilization and embryo transfer for the treatment of infertility associated with polycystic ovary syndrome. Fertil. Steril., 60, 858\u2013863.","DOI":"10.1016\/S0015-0282(16)56287-6"},{"key":"key\n\t\t\t\t20170410032821_HOMBURG-ETAL-1993B","doi-asserted-by":"crossref","unstructured":"Homburg, R., Levy, T., Berkovitz, D. et al. (1993b) Gonadotropin-releasing hormone agonist reduces the miscarriage rate for pregnancies achieved in women with polycystic ovarian syndrome. Fertil. Steril., 59, 527\u2013531.","DOI":"10.1016\/S0015-0282(16)55794-X"},{"key":"key\n\t\t\t\t20170410032821_HOWLES-ETAL-1986","doi-asserted-by":"crossref","unstructured":"Howles, C.M., McNamee, M.C., Edwards, R.G. et al. (1986) Effects of high tonic levels of luteinising hormone on outcome of in vitro fertilisation. Lancet, ii, 521\u2013523.","DOI":"10.1016\/S0140-6736(86)90395-8"},{"key":"key\n\t\t\t\t20170410032821_ISAACS-ETAL-1997","doi-asserted-by":"crossref","unstructured":"Isaacs, J.D., Lincoln, S.R. and Cowan, B.D. (1997) Extended clomiphene citrate (CC) and prednisone for the treatment of chronic anovulation resistant to CC alone. Fertil. Steril., 67, 641\u2013643.","DOI":"10.1016\/S0015-0282(97)81359-3"},{"key":"key\n\t\t\t\t20170410032821_JONES-ETAL-1953","doi-asserted-by":"crossref","unstructured":"Jones, G.E.S., Howard, J.E. and Langford, H. (1953) The use of cortisone in follicular phase disturbances. Fertil. Steril., 4, 49\u201362.","DOI":"10.1016\/S0015-0282(16)31144-X"},{"key":"key\n\t\t\t\t20170410032821_KEMETER-AND-FEICHTINGER-1986","doi-asserted-by":"crossref","unstructured":"Kemeter, P. and Feichtinger, W. (1986) Prednisolone supplementation to clomid and\/or gonadotrophin stimulation for in-vitro fertilization\u2014a prospective randomized trial. Hum. Reprod., 1, 441\u2013444.","DOI":"10.1093\/oxfordjournals.humrep.a136451"},{"key":"key\n\t\t\t\t20170410032821_KRUGER-ETAL-1987","doi-asserted-by":"crossref","unstructured":"Kru\u0308ger, T.F., Acosta, A.A., Simmons, K.F. et al. (1987) A new method of evaluating sperm morphology with predictive value for IVF. Urology, 30, 248\u2013251.","DOI":"10.1016\/0090-4295(87)90246-9"},{"key":"key\n\t\t\t\t20170410032821_LOBO-ETAL-1982","unstructured":"Lobo, R.A., Paul, W., March, C.M. et al. (1982) Clomiphene and dexamethasone in women unresponsive to clomiphene alone. Obstet. Gynecol., 60, 497\u2013501."},{"key":"key\n\t\t\t\t20170410032821_LONGCOPE-1996","unstructured":"Longcope, C. (1996) Dehydroepiandrosterone metabolism. J. Endocrinol., 150, 125\u2013127."},{"key":"key\n\t\t\t\t20170410032821_MAHOUDEAU-ETAL-1972","doi-asserted-by":"crossref","unstructured":"Mahoudeau, J.A., Bardin, C.W. and Lipsett, M.B. (1972) The metabolic clearance rate and origin of plasma dihydro T in man and its conversion to the 5\u03b1-androstanediols. J. Clin. Invest., 50, 1338\u20131344.","DOI":"10.1172\/JCI106613"},{"key":"key\n\t\t\t\t20170410032821_MOHR-AND-TROUNSON-1985","doi-asserted-by":"crossref","unstructured":"Mohr, L.R. and Trounson, A.O. (1985) Cryopreservation of human embryos. Ann. N. Y. Acad. Sci., 442, 536\u2013543.","DOI":"10.1111\/j.1749-6632.1985.tb37562.x"},{"key":"key\n\t\t\t\t20170410032821_OLIVENNES-AND-FRYDMAN-1998","doi-asserted-by":"crossref","unstructured":"Olivennes, F. and Frydman, R. (1998) Friendly IVF: the way of the future? Hum. Reprod., 13, 1121\u20131124.","DOI":"10.1093\/humrep\/13.5.1121"},{"key":"key\n\t\t\t\t20170410032821_POLAK-DE-FRIED-ETAL-1993","doi-asserted-by":"crossref","unstructured":"Polak de Fried, E., Blanco, L., Lancuba, S. et al. (1993) Improvement of clinical pregnancy rate and implantation rate of in-vitro fertilization\u2013 embryo transfer patients by using methylprednisone. Hum. Reprod., 8, 393\u2013395.","DOI":"10.1093\/oxfordjournals.humrep.a138058"},{"key":"key\n\t\t\t\t20170410032821_REGAN-1991","unstructured":"Regan, L. (1991) The luteinizing hormone hypothesis \u2013 high follicular phase luteinizing hormone. Lessons from assisted conception and anovulatory infertility. In Howles, C.M. (ed.), Gonadotrophins, Gonadotrophin-Releasing Hormone Analogues and Growth Factors in Infertility: Future Perspectives. Alden Press, Oxford, pp. 29\u201342."},{"key":"key\n\t\t\t\t20170410032821_REIN-ETAL-1996","doi-asserted-by":"crossref","unstructured":"Rein, M.S., Jackson, K.V., Sable, D.B. et al. (1996) Dexamethasone during ovulation induction for in-vitro fertilization: a pilot study. Hum. Reprod., 11, 253\u2013255.","DOI":"10.1093\/HUMREP\/11.2.253"},{"key":"key\n\t\t\t\t20170410032821_SHOHAM-ETAL-1993","doi-asserted-by":"crossref","unstructured":"Shoham, Z., Jacobs, H.S., Insler, V. (1993) Luteinizing hormone: its role, mechanism of action, and detrimental effects when hypersecreted during the follicular phase. Fertil. Steril., 59, 1153\u20131161.","DOI":"10.1016\/S0015-0282(16)55968-8"},{"key":"key\n\t\t\t\t20170410032821_SINGH-ETAL-1992","unstructured":"Singh, K.B., Dunnihoo, D.R., Mahajan, D.K. et al. (1992) Clomiphene\u2013dexamethasone treatment of clomiphene-resistant women with and without the polycystic ovary syndrome. J. Reprod. Med., 37, 215\u2013218."},{"key":"key\n\t\t\t\t20170410032821_STEGE-ETAL-1987","doi-asserted-by":"crossref","unstructured":"Stege, R., Eriksson, A., Henriksson, P. et al. (1987) Orchidectomy or estrogen treatment in prostatic cancer: effects on serum levels of adrenal androgens and related steroids. Int. J. Androl., 10, 581\u2013587.","DOI":"10.1111\/j.1365-2605.1987.tb00357.x"},{"key":"key\n\t\t\t\t20170410032821_TULCHINSKY-AND-LITTLE-1994","unstructured":"Tulchinsky, D. and Little, A.B. (1994) Maternal \u2013 Fetal Endocrinology, 2nd Edn. Saunders, Philadelphia, pp. 34\u201337."}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/14\/6\/1440\/11495649\/141440.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,8]],"date-time":"2017-12-08T14:11:46Z","timestamp":1512742306000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humrep\/article-lookup\/doi\/10.1093\/humrep\/14.6.1440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,6]]},"references-count":40,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1999,6]]},"published-print":{"date-parts":[[1999,6]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/14.6.1440","relation":{},"ISSN":["1460-2350","0268-1161"],"issn-type":[{"value":"1460-2350","type":"electronic"},{"value":"0268-1161","type":"print"}],"subject":[],"published":{"date-parts":[[1999,6]]}}}