{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:04:20Z","timestamp":1773014660008,"version":"3.50.1"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,6]]},"DOI":"10.1093\/humrep\/15.6.1261","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T22:22:29Z","timestamp":1027722149000},"page":"1261-1265","source":"Crossref","is-referenced-by-count":60,"title":["CA125 production by the peritoneum: in-vitro and in-vivo studies"],"prefix":"10.1093","volume":"15","author":[{"given":"M.","family":"Epiney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Bertossa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Weil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Campana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Bischof","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2000,6]]},"reference":[{"key":"key\n\t\t\t\t20170410034015_ABRAO-ETAL-1997","doi-asserted-by":"crossref","unstructured":"Abrao, M.S., Podgaec, S., Braz, M.F. et al. (1997) The use of biochemical markers in the diagnosis of pelvic endometriosis. Hum. Reprod., 12, 2523\u20132527.","DOI":"10.1093\/humrep\/12.11.2523"},{"key":"key\n\t\t\t\t20170410034015_BARBATI-ETAL-1990","doi-asserted-by":"crossref","unstructured":"Barbati, A., Anceschi, M.M., Broccucci, L. et al. (1990) CA125 is released by human amnion cells in culture. Am. J. Obstet. Gynecol., 162, 266\u2013268.","DOI":"10.1016\/0002-9378(90)90862-2"},{"key":"key\n\t\t\t\t20170410034015_BARBIERI-ETAL-1986","doi-asserted-by":"crossref","unstructured":"Barbieri, R.L., Niloff, J.M., Bast, R.C. et al. (1986) Elevated serum concentrations of CA125 in patients with advanced endometriosis. Fertil. Steril., 45, 630\u2013634.","DOI":"10.1016\/S0015-0282(16)49333-7"},{"key":"key\n\t\t\t\t20170410034015_BAST-ETAL-1981","doi-asserted-by":"crossref","unstructured":"Bast, R.C., Feeney, M., Lazarus, H. et al. (1981) Reactivity of a monoclonal antibody with human ovarian carcinoma. J. Clin. Invest., 68, 1331\u20131337.","DOI":"10.1172\/JCI110380"},{"key":"key\n\t\t\t\t20170410034015_BAST-ETAL-1983","doi-asserted-by":"crossref","unstructured":"Bast, R.C., Klug, T.L., St John, E. et al. (1983) A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer. N. Engl. J. Med., 309, 883\u2013887.","DOI":"10.1056\/NEJM198310133091503"},{"key":"key\n\t\t\t\t20170410034015_BERGMANN-ETAL-1987","doi-asserted-by":"crossref","unstructured":"Bergmann, J.F., Bidart, J.M., George, M. et al. (1987) Elevation of CA125 in patients with benign and malignant ascites. Cancer, 59, 213\u2013217.","DOI":"10.1002\/1097-0142(19870115)59:2<213::AID-CNCR2820590206>3.0.CO;2-I"},{"key":"key\n\t\t\t\t20170410034015_BISCHOF-ETAL-1986","doi-asserted-by":"crossref","unstructured":"Bischof, P., Tseng, L., Brioschi, P.A. et al. (1986) Cancer antigen 125 is produced by human endometrial stromal cells. Hum. Reprod., 1, 423\u2013426.","DOI":"10.1093\/oxfordjournals.humrep.a136445"},{"key":"key\n\t\t\t\t20170410034015_BISCHOF-ETAL-1989","doi-asserted-by":"crossref","unstructured":"Bischof, P., Mignot, T.M. and Ce\u0301dard, L. (1989) Are pregnancy-associated plasma protein-A (PAPP-A) and CA125 measurements after IVF-ET possible predictors of early pregnancy wastage? Hum. Reprod., 4, 843\u2013847.","DOI":"10.1093\/oxfordjournals.humrep.a136998"},{"key":"key\n\t\t\t\t20170410034015_BISCHOF-ETAL-1992","doi-asserted-by":"crossref","unstructured":"Bischof, P., Galfetti, M.A., Seydoux, J. et al. (1992) Peripheral CA125 levels in patients with uterine fibroids. Hum. Reprod., 7, 35\u201338.","DOI":"10.1093\/oxfordjournals.humrep.a137552"},{"key":"key\n\t\t\t\t20170410034015_BON-ETAL-1999","doi-asserted-by":"crossref","unstructured":"Bon, G, Kenemans, P., Dekker, J. et al. (1999) Fluctuations in CA125 and CA 15\u20133 serum concentrations during spontaneous ovulatory cycles. Hum. Reprod., 14, 566\u2013570.","DOI":"10.1093\/humrep\/14.2.566"},{"key":"key\n\t\t\t\t20170410034015_DE-BRUIJN-ETAL-1986","doi-asserted-by":"crossref","unstructured":"De Bruijn, H.W.A., Van Beeck Calkoen-Carpay, T., Jager, S. et al. (1986) The tumor marker CA125 is a common constituent of normal cervical mucus. Am. J. Obstet. Gynecol., 154, 1088\u20131091.","DOI":"10.1016\/0002-9378(86)90757-X"},{"key":"key\n\t\t\t\t20170410034015_DIETEL-ETAL-1986","doi-asserted-by":"crossref","unstructured":"Dietel, M., Arps, H., Klapdor, R. et al. (1986) Antigen detection by monoclonal antibodies CA 19\u20139 and CA125 in normal and tumor tissue and patients' sera. J. Cancer Res. Clin. Oncol., 111, 257\u2013265.","DOI":"10.1007\/BF00389242"},{"key":"key\n\t\t\t\t20170410034015_FEDELE-ETAL-1988","doi-asserted-by":"crossref","unstructured":"Fedele, L., Vercellini, P., Arcaini, L. et al. (1988) CA125 in serum, peritoneal fluid, active lesions and endometrium of patients with endometriosis. Am. J. Obstet. Gynecol., 158, 166\u2013170.","DOI":"10.1016\/0002-9378(88)90803-4"},{"key":"key\n\t\t\t\t20170410034015_DUK-ETAL-1988","doi-asserted-by":"crossref","unstructured":"Duk, J.M, Aalders, J.G., Fleuren, G.J. et al. (1988) CA125: a useful marker in endometrial carcinoma. Am. J. Obstet. Gynecol., 155, 1097\u20131101.","DOI":"10.1016\/0002-9378(86)90358-3"},{"key":"key\n\t\t\t\t20170410034015_GARZETTI-ETAL-1994","doi-asserted-by":"crossref","unstructured":"Garzetti, G.G., Ciavattini, A., Tranquilli, A.L. et al. (1994) Serum CA125 concentration in endometriosis patients: role of pelvic and peritoneal irritation. Gynecol. Endocrinol., 8, 27\u201331.","DOI":"10.3109\/09513599409028454"},{"key":"key\n\t\t\t\t20170410034015_HAGA-ETAL-1986","doi-asserted-by":"crossref","unstructured":"Haga, Y, Sakamoto, K., Egami, H. et al. (1986) Clinical significance of serum CA125 values in patients with cancers of the digestive system. Am. J. Med. Sci., 292, 30\u201334.","DOI":"10.1097\/00000441-198607000-00006"},{"key":"key\n\t\t\t\t20170410034015_HALILA-ETAL-1986","doi-asserted-by":"crossref","unstructured":"Halila, H., Stenman, U.H. and Seppala, M. (1986) Ovarian cancer antigen CA125 levels in pelvic inflammatory disease and pregnancy. Cancer, 57, 1327\u20131329.","DOI":"10.1002\/1097-0142(19860401)57:7<1327::AID-CNCR2820570713>3.0.CO;2-Z"},{"key":"key\n\t\t\t\t20170410034015_HO-ETAL-1997","doi-asserted-by":"crossref","unstructured":"Ho, H.N., Wu, M.Y., Chen, S.U. et al. (1997) Total antioxidant status and nitric oxide do not increase in peritoneal fluids from women with endometriosis. Hum. Reprod., 12, 2810\u20132815.","DOI":"10.1093\/humrep\/12.12.2810"},{"key":"key\n\t\t\t\t20170410034015_JACOBS-ETAL-1988","doi-asserted-by":"crossref","unstructured":"Jacobs, I.J., Fay, T.N., Stabile, I. et al. (1988) The distribution of CA125 in the reproductive tract of pregnant and non-pregnant women. Br. J. Obstet. Gynecol., 95, 1190\u20131194.","DOI":"10.1111\/j.1471-0528.1988.tb06798.x"},{"key":"key\n\t\t\t\t20170410034015_JOHANSSON-ETAL-1998","doi-asserted-by":"crossref","unstructured":"Johansson, J., Santala, M. and Kauppila, A. (1998) Explosive rise of serum CA125 following the rupture of ovarian endometrioma. Hum. Reprod., 12, 3503\u20133504.","DOI":"10.1093\/humrep\/13.12.3503"},{"key":"key\n\t\t\t\t20170410034015_KABAWAT-ETAL-1983","doi-asserted-by":"crossref","unstructured":"Kabawat, S.E., Bast, R.C., Bahn, A.K. et al. (1983) Tissue distribution of a coelomic-epithelium-related antigen recognized by the monoclonal antibody OC 125. Int. J. Gynecol. Pathol., 2, 275\u2013285.","DOI":"10.1097\/00004347-198303000-00005"},{"key":"key\n\t\t\t\t20170410034015_LEHTOVIRTA-ETAL-1990","doi-asserted-by":"crossref","unstructured":"Lehtovirta, P., Apter, D. and Stenman, U.H. (1990) Serum CA125 levels during the menstrual cycle. Br. J. Obstet. Gynecol., 97, 930\u2013933.","DOI":"10.1111\/j.1471-0528.1990.tb02449.x"},{"key":"key\n\t\t\t\t20170410034015_MEISSER-ETAL-1996","doi-asserted-by":"crossref","unstructured":"Meisser, A., Campana, A. and Bischof, P. (1996) CA125 in seminal plasma, correlation with semen parameters. Hum. Reprod., 11, 574\u2013578.","DOI":"10.1093\/HUMREP\/11.3.574"},{"key":"key\n\t\t\t\t20170410034015_NOUWEN-ETAL-1987","unstructured":"Nouwen, E.J., Hendrix, P.G., Dauwe, S. et al. (1987) Tumor markers in the human ovary and its neoplasms. A comparative immunohistochemical study. Am. J. Pathol., 126, 230\u2013242."},{"key":"key\n\t\t\t\t20170410034015_OBRIEN-ETAL-1986","doi-asserted-by":"crossref","unstructured":"O'Brien, T.J., Hardin, J.W., Bannon, G.A. et al. (1986) CA125 antigen in human amniotic fluid and fetal membranes. Am. J. Obstet. Gynecol., 155, 50\u201355.","DOI":"10.1016\/0002-9378(86)90076-1"},{"key":"key\n\t\t\t\t20170410034015_PAAVONEN-ETAL-1989","doi-asserted-by":"crossref","unstructured":"Paavonen, J., Miettinen, A., Heinonen, P.K. et al. (1989) Serum CA125 in acute pelvic inflammatory disease. Br. J. Obstet. Gynecol., 96, 574\u2013579.","DOI":"10.1111\/j.1471-0528.1989.tb03259.x"},{"key":"key\n\t\t\t\t20170410034015_PITTAWAY-AND-FAYEZ-1987","doi-asserted-by":"crossref","unstructured":"Pittaway, D.E. and Fayez, J.A. (1987) Serum CA125 antigen levels increase during the menses. Am. J. Obstet. Gynecol., 156, 75\u201376.","DOI":"10.1016\/0002-9378(87)90207-9"},{"key":"key\n\t\t\t\t20170410034015_REDMAN-ETAL-1988","doi-asserted-by":"crossref","unstructured":"Redman, C.W.E., Jones, S.R., Luesley, D.M. et al. (1988) Peritoneal trauma releases CA125? Br. J. Cancer, 58, 502\u2013504.","DOI":"10.1038\/bjc.1988.250"},{"key":"key\n\t\t\t\t20170410034015_SCHWARTZ-ETAL-1989","unstructured":"Schwartz, P.E., Chambers, S.K., Chambers, J.T. et al. (1989) CA125 in peritoneal washings and fluid: correlation with plasma CA125 and peritoneal cytology. Obstet. Gynecol., 73, 339\u2013342."},{"key":"key\n\t\t\t\t20170410034015_TAKAHASHI-ETAL-1990","doi-asserted-by":"crossref","unstructured":"Takahashi, K, Nagata, H., Abu Musa, A. et al. (1990) Clinical usefulness of CA125 levels in the menstrual discharge in patients with endometriosis. Fertil. Steril., 54, 360\u2013362.","DOI":"10.1016\/S0015-0282(16)53721-2"},{"key":"key\n\t\t\t\t20170410034015_TALBOT-ETAL-1989","unstructured":"Talbot, R., Jacobsen, D.J., Nagorney, D.M. et al. (1989) Temporary elevation of CA125 after abdominal surgical treatment for benign diseases and cancer. Surg. Gynecol. Obstet., 168, 407\u2013412."},{"key":"key\n\t\t\t\t20170410034015_WEINTRAUB-ETAL-1990","doi-asserted-by":"crossref","unstructured":"Weintraub, J., Bischof, P., Tseng, L. et al. (1990) CA125 is an excretory product of human endometrial glands. Biol. Reprod., 42, 721\u2013726.","DOI":"10.1095\/biolreprod42.4.721"},{"key":"key\n\t\t\t\t20170410034015_YEDEMA-ETAL-1993","doi-asserted-by":"crossref","unstructured":"Yedema, C.A., Kenemans, P., Thomas, C.M. et al. (1993) CA125 serum levels in the early post-operative period do not reflect tumour reduction obtained by cytoreductive surgery. Eur. J. Cancer, 29A, 966\u2013971.","DOI":"10.1016\/S0959-8049(05)80203-5"},{"key":"key\n\t\t\t\t20170410034015_ZEILLEMAKER-ETAL-1994","doi-asserted-by":"crossref","unstructured":"Zeillemaker, A.M., Verbrugh, H.A., Hoynck van Papendrecht, A.A.G.M. et al. (1994) CA125 secretion by peritoneal mesothelial cells. J. Clin. Pathol., 47, 263\u2013265.","DOI":"10.1136\/jcp.47.3.263"},{"key":"key\n\t\t\t\t20170410034015_ZEIMET-ETAL-1997","unstructured":"Zeimet, A.G., Offner, F.A., Marth, C. et al. (1997) Modulation of CA125 release by inflammatory cytokines in human peritoneal mesothelial and ovarian cancer cells. Anticancer Res., 17, 3129\u20133132"},{"key":"key\n\t\t\t\t20170410034015_ZEIMET-ETAL-1998","doi-asserted-by":"crossref","unstructured":"Zeimet, A.G., Offner, F.A., Muller-Holzner, E. et al. (1998) Peritoneum and tissues of the female reproductive tract as physiological sources of CA125. Tumor Biol., 19, 275\u2013282.","DOI":"10.1159\/000030018"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","deposited":{"date-parts":[[2017,6,15]],"date-time":"2017-06-15T07:10:58Z","timestamp":1497510658000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humrep\/article-lookup\/doi\/10.1093\/humrep\/15.6.1261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,6]]},"references-count":36,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2000,6]]},"published-print":{"date-parts":[[2000,6]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/15.6.1261","relation":{},"ISSN":["1460-2350","0268-1161"],"issn-type":[{"value":"1460-2350","type":"electronic"},{"value":"0268-1161","type":"print"}],"subject":[],"published":{"date-parts":[[2000,6]]}}}