{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T01:49:21Z","timestamp":1777340961645,"version":"3.51.4"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,3,1]]},"DOI":"10.1093\/humrep\/deh685","type":"journal-article","created":{"date-parts":[[2004,12,17]],"date-time":"2004-12-17T20:12:55Z","timestamp":1103314375000},"page":"642-648","source":"Crossref","is-referenced-by-count":56,"title":["Minimal stimulation IVF with late follicular phase administration of the GnRH antagonist cetrorelix and concomitant substitution with recombinant FSH: a pilot study"],"prefix":"10.1093","volume":"20","author":[{"given":"M.J.","family":"Pelinck","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.E.A.","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Hoek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.G.J.M.","family":"Arts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.H.M.","family":"Simons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.J.","family":"Heineman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2005,3]]},"reference":[{"key":"key\n\t\t\t\t20171011135454_R1","doi-asserted-by":"crossref","unstructured":"Aboulghar MA, Mansour RT, Serour GA, Amin YM, Sattar MA and Ramzy AM (1995) In vitro fertilization in a spontaneous cycle: a successful simple protocol. J Obstet Gynaecol21, 337\u2013340.","DOI":"10.1111\/j.1447-0756.1995.tb01020.x"},{"key":"key\n\t\t\t\t20171011135454_R2","doi-asserted-by":"crossref","unstructured":"Albano C, Smitz J, Camus M, Riethmuller-Winzen H, Van Steirteghem A and Devroey P (1997) Comparison of different doses of gonadotropin-releasing hormone antagonist Cetrorelix during controlled ovarian hyperstimulation. Fertil Steril67, 917\u2013922.","DOI":"10.1016\/S0015-0282(97)81407-0"},{"key":"key\n\t\t\t\t20171011135454_R3","doi-asserted-by":"crossref","unstructured":"Al-Inany H and Aboulghar M (2002) GnRH antagonist in assisted reproduction: a Cochrane review. Hum Reprod17, 874\u2013885.","DOI":"10.1093\/humrep\/17.4.874"},{"key":"key\n\t\t\t\t20171011135454_R4","doi-asserted-by":"crossref","unstructured":"Basir GS, O WS, Ng EHY and Ho PC (2001) Morphometric analysis of peri-implantation endometrium in patients having excessively high oestradiol concentrations after ovarian stimulation. Hum Reprod16, 435\u2013440.","DOI":"10.1093\/humrep\/16.3.435"},{"key":"key\n\t\t\t\t20171011135454_R5","doi-asserted-by":"crossref","unstructured":"Bassil S, Godin PA and Donnez J (1999) Outcome of in-vitro fertilization through natural cycles in poor responders. Hum Reprod14, 1262\u20131265.","DOI":"10.1093\/humrep\/14.5.1262"},{"key":"key\n\t\t\t\t20171011135454_R6","doi-asserted-by":"crossref","unstructured":"Bauman R, Mihaljevic D, Kupesic S and Kurjak A (2002) In vitro fertilization in spontaneous cycles - our experience. Eur J Obstet Gynecol Reprod Biol102, 184\u2013187.","DOI":"10.1016\/S0301-2115(01)00594-2"},{"key":"key\n\t\t\t\t20171011135454_R7","doi-asserted-by":"crossref","unstructured":"Ben-Chetrit A, Gotlieb L, Wong PY and Casper RF (1996) Ovarian response to recombinant human follicle-stimulating hormone in luteinizing hormone-depleted women: examination of the two cell, two gonadotropin theory. Fertil Steril65, 711\u2013717.","DOI":"10.1016\/S0015-0282(16)58201-6"},{"key":"key\n\t\t\t\t20171011135454_R8","doi-asserted-by":"crossref","unstructured":"Bourgain C and Devroey P (2003) The endometrium in stimulated cycles for IVF. Hum Reprod Update9, 515\u2013522.","DOI":"10.1093\/humupd\/dmg045"},{"key":"key\n\t\t\t\t20171011135454_R9","doi-asserted-by":"crossref","unstructured":"Daya S, Gunby J, Hughes EG, Collins JA, Sagle MA and YoungLai EV (1995) Natural cyles for in-vitro fertilization: cost-effectiveness analysis and factors influencing outcome. Hum Reprod10, 1719\u20131724.","DOI":"10.1093\/oxfordjournals.humrep.a136162"},{"key":"key\n\t\t\t\t20171011135454_R10","doi-asserted-by":"crossref","unstructured":"De Sutter P, Van der Elst J, Coetsier T and Dhont M (2003) Single embryo transfer and multiple pregnancy rate reduction in IVF\/ICSI: a 5-year appraisal. Reprod Biomed Online6, 464\u2013469.","DOI":"10.1016\/S1472-6483(10)62169-4"},{"key":"key\n\t\t\t\t20171011135454_R11","doi-asserted-by":"crossref","unstructured":"Duijkers IJM, Klipping C, Willemsen WNP, Krone D, Schneider E, Niebch G and Hermann R (1998) Single and multiple dose pharmacokinetics and pharmacodynamics of the gonadotrophin-releasing hormone antagonist Cetrorelix in healthy female volunteers. Hum Reprod13, 2392\u20132398.","DOI":"10.1093\/humrep\/13.9.2392"},{"key":"key\n\t\t\t\t20171011135454_R12","doi-asserted-by":"crossref","unstructured":"Feldman B, Seidman DS, Levron J, Bider D, Shulman A, Shine S and Dor J (2001) In vitro fertilization following natural cycles in poor responders. Gynecol Endocrinol15, 328\u2013334.","DOI":"10.1080\/gye.15.5.328.334"},{"key":"key\n\t\t\t\t20171011135454_R13","unstructured":"Fossum GT, Davidson A and Paulson RJ (1989) Ovarian hyperstimulation inhibits embryo implantation in the mouse. J In Vitro Fertil Embryo Transf6, 7\u201310."},{"key":"key\n\t\t\t\t20171011135454_R14","doi-asserted-by":"crossref","unstructured":"Gerris J and Van Royen E (2000) Avoiding multiple pregnancies in ART: a plea for single embryo transfer. Hum Reprod15, 1884\u20131888.","DOI":"10.1093\/humrep\/15.9.1884"},{"key":"key\n\t\t\t\t20171011135454_R15","doi-asserted-by":"crossref","unstructured":"Gerris J, de Neubourg D, Mangelschots K, Van Royen E, Vercruyssen M, Barudy-Vasquez J, Valkenburg M and Ryckaert G (2002) Elective single day 3 embryo transfer halves the twinning rate without decrease in the ongoing pregnancy rate of an IVF\/ICSI programme. Hum Reprod17, 2626\u20132631.","DOI":"10.1093\/humrep\/17.10.2626"},{"key":"key\n\t\t\t\t20171011135454_R16","doi-asserted-by":"crossref","unstructured":"Gerris J, de Sutter P, de Neubourg D, Van Royen E, Van der Elst J, Mangelschots K, Vercruyssen M, Kok P, Elseviers M, Annemans L et al. (2004) A real-life prospective health economic study of elective single embryo transfer versus two-embryo transfer in first IVF\/ICSI cycles. Hum Reprod19, 917\u2013923.","DOI":"10.1093\/humrep\/deh188"},{"key":"key\n\t\t\t\t20171011135454_R17","doi-asserted-by":"crossref","unstructured":"H\u00f8jgaard A, Ingerslev HJ and Dinesen J (2001) Friendly IVF: patient opinions. Hum Reprod16, 1391\u20131396.","DOI":"10.1093\/humrep\/16.7.1391"},{"key":"key\n\t\t\t\t20171011135454_R18","doi-asserted-by":"crossref","unstructured":"Ingerslev HJ, H\u00f8jgaard A, Hindkj\u00e6r J and Kesmodel U (2001) A randomized study comparing IVF in the unstimulated cycle with IVF following clomiphene citrate. Hum Reprod16, 696\u2013702.","DOI":"10.1093\/humrep\/16.4.696"},{"key":"key\n\t\t\t\t20171011135454_R19","doi-asserted-by":"crossref","unstructured":"Janssens RMJ, Lambalk CB, Vermeiden JPW, Schats R and Schoemaker J (2000) In-vitro fertilization in a spontaneous cycle: easy, cheap and realistic. Hum Reprod15, 314\u2013318.","DOI":"10.1093\/humrep\/15.2.314"},{"key":"key\n\t\t\t\t20171011135454_R20","doi-asserted-by":"crossref","unstructured":"Lindheim SR, Vidali A, Ditkoff E and Sauer MV (1997) Poor responders to ovarian hyperstimulation may benefit from an attempt at natural-cycle oocyte retrieval. J Assist Reprod Genet14, 174\u2013176.","DOI":"10.1007\/BF02766136"},{"key":"key\n\t\t\t\t20171011135454_R21","doi-asserted-by":"crossref","unstructured":"Lukassen HG, Kremer JA, Lindeman EJ, Braat DD and Wetzels AM (2003) A pilot study of the efficacy of intracytoplasmic sperm injection in a natural cycle. Fertil Steril79, 231\u2013232.","DOI":"10.1016\/S0015-0282(02)04405-9"},{"key":"key\n\t\t\t\t20171011135454_R22","doi-asserted-by":"crossref","unstructured":"Meldrum DR, Rivier J, Garzo G, Wisot A, Stubbs C and Hamilton F (1994) Successful pregnancies with unstimulated cycle oocyte donation using an antagonist of gonadotropin-releasing hormone. Fertil Steril61, 556\u2013557.","DOI":"10.1016\/S0015-0282(16)56594-7"},{"key":"key\n\t\t\t\t20171011135454_R23","doi-asserted-by":"crossref","unstructured":"Morgia F, Sbracia M, Schimberni M, Giallonardo A, Piscitelli C, Giannini P and Aragona C (2004) A controlled trial of natural cycle versus microdose gonadotropin-releasing hormone analog flare cycles in poor responders undergoing in vitro fertilization. Fertil Steril81, 1542\u20131547.","DOI":"10.1016\/j.fertnstert.2003.11.031"},{"key":"key\n\t\t\t\t20171011135454_R24","doi-asserted-by":"crossref","unstructured":"Murray S, Shetty A, Rattray A, Taylor V and Bhattacharya S (2004) A randomized comparison of alternative methods of information provision on the acceptability of elective single embryo transfer. Hum Reprod19, 911\u2013916.","DOI":"10.1093\/humrep\/deh176"},{"key":"key\n\t\t\t\t20171011135454_R25","doi-asserted-by":"crossref","unstructured":"Nargund G, Waterstone J, Bland JM, Philips Z, Parsons J and Campbell S (2001) Cumulative conception and live birth rates in natural (unstimulated) IVF cycles. Hum Reprod16, 259\u2013262.","DOI":"10.1093\/humrep\/16.2.259"},{"key":"key\n\t\t\t\t20171011135454_R26","unstructured":"Ng EHY, Chui DKC, Tang OS, Lau EY, Yeung WS and Chung HP (2001) In vitro fertilization and embryo transfer during natural cycles. J Reprod Med46, 95\u201399."},{"key":"key\n\t\t\t\t20171011135454_R27","doi-asserted-by":"crossref","unstructured":"Olivennes F and Frydman R (1998) Friendly IVF: the way of the future? Hum Reprod13, 1121\u20131124.","DOI":"10.1093\/humrep\/13.5.1121"},{"key":"key\n\t\t\t\t20171011135454_R28","doi-asserted-by":"crossref","unstructured":"Omland AK, Fedors\u00e1k P, Storeng R, Dale PO, \u00c5byholm T and Tanbo T (2001) Natural cycle IVF in unexplained, endometriosis-associated and tubal factor infertility. Hum Reprod16, 2587\u20132592.","DOI":"10.1093\/humrep\/16.12.2587"},{"key":"key\n\t\t\t\t20171011135454_R29","doi-asserted-by":"crossref","unstructured":"Ozturk O, Bhattacharya S and Templeton A (2001) Avoiding multiple pregnancies in ART: evaluation and implementation of new strategies. Hum Reprod16, 1319\u20131321.","DOI":"10.1093\/humrep\/16.7.1319"},{"key":"key\n\t\t\t\t20171011135454_R30","doi-asserted-by":"crossref","unstructured":"Paulson RJ, Sauer MV and Lobo RA (1994) Addition of a gonadotropin releasing hormone (GnRH) antagonist and exogenous gonadotropins to unstimulated in vitro fertilization (IVF) cycles: physiologic observations and preliminary experience. J Assist Reprod Genet11, 28\u201332.","DOI":"10.1007\/BF02213694"},{"key":"key\n\t\t\t\t20171011135454_R31","doi-asserted-by":"crossref","unstructured":"Pelinck MJ, Hoek A, Simons AHM and Heineman MJ (2002) Efficacy of natural cycle IVF: a review of the literature. Hum Reprod Update8, 129\u2013139.","DOI":"10.1093\/humupd\/8.2.129"},{"key":"key\n\t\t\t\t20171011135454_R32","doi-asserted-by":"crossref","unstructured":"Ragni G, Vegetti W, Baroni E, Colomba M, Arnoldi M, Lombroso G and Crosignani G (2001) Comparison of luteal phase profile in gonadotrophin stimulated cycles with or without a gonadotrophin-releasing hormone antagonist. Hum Reprod16, 2258\u20132262.","DOI":"10.1093\/humrep\/16.11.2258"},{"key":"key\n\t\t\t\t20171011135454_R33","doi-asserted-by":"crossref","unstructured":"Relji\u010d M and Vlaisavljevi\u0107 V (1999) The preovulatory serum estradiol pattern in natural IVF\/ICSI cycles. J Assist Reprod Genet16, 535\u2013539.","DOI":"10.1023\/A:1020549221164"},{"key":"key\n\t\t\t\t20171011135454_R34","doi-asserted-by":"crossref","unstructured":"Relji\u010d M, Vlaisavljevi\u0107 V, Gavri\u0107 V, Kova\u010di\u010d B and \u010ci\u017eek-Sajko M (2001) Value of the serum estradiol level on the day of human chorionic gonadotropin injection and on the day after in predicting the outcome in natural in vitro fertilization\/intracytoplasmic sperm injection cycles. Fertil Steril75, 539\u2013543.","DOI":"10.1016\/S0015-0282(00)01735-0"},{"key":"key\n\t\t\t\t20171011135454_R35","doi-asserted-by":"crossref","unstructured":"Rongi\u00e8res-Bertrand C, Olivennes F, Righini C, Franchin R, Ta\u00efeb J, Hamamah S, Bouchard P and Frydman R (1999) Revival of the natural cycles in in-vitro fertilization with the use of a new gonadotrophin-releasing hormone antagonist (Cetrorelix): a pilot study with minimal stimulation. Hum Reprod14, 683\u2013688.","DOI":"10.1093\/humrep\/14.3.683"},{"key":"key\n\t\t\t\t20171011135454_R36","doi-asserted-by":"crossref","unstructured":"Sim\u00f3n C, Garcia Velasco JJ, Valbue\u00f1a D, Peinado JA, Moreno C, Remoh\u00ed J and Pellicer A (1998) Increasing uterine receptivity by decreasing estradiol levels during the preimplantation period in high responders with the use of a follicle-stimulating hormone step-down regimen. Fertil Steril70, 234\u2013239.","DOI":"10.1016\/S0015-0282(98)00140-X"},{"key":"key\n\t\t\t\t20171011135454_R37","unstructured":"Sullivan MW, Stewart-Akers A, Krasnow JS, Berga SL and Zeleznik AJ (1999) Ovarian responses in women to recombinant follicle-stimulating hormone and luteinizing hormone (LH): a role for LH in the final stages of follicular maturation. J Clin Endocrinol Metab84, 228\u2013232."},{"key":"key\n\t\t\t\t20171011135454_R38","doi-asserted-by":"crossref","unstructured":"Tiitinen A, Halttunen M, H\u00e4rkki P, Vuoristo P and Hyden-Granskog C (2001) Elective single embryo transfer: the value of cryopreservation. Hum Reprod16, 1140\u20131144.","DOI":"10.1093\/humrep\/16.6.1140"},{"key":"key\n\t\t\t\t20171011135454_R39","doi-asserted-by":"crossref","unstructured":"Tiitinen A, Unkila-Kallio L, Halttunen M and Hyden-Granskog C (2003) Impact of elective single embryo transfer on the twin pregnancy rate. Hum Reprod18, 1449\u20131453.","DOI":"10.1093\/humrep\/deg301"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/20\/3\/642\/6953292\/deh685.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T11:49:04Z","timestamp":1546429744000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/humrep\/article\/20\/3\/642\/2356629\/Minimal-stimulation-IVF-with-late-follicular-phase"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3,1]]},"references-count":39,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2005,3]]},"published-print":{"date-parts":[[2005,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/deh685","relation":{},"ISSN":["1460-2350","0268-1161"],"issn-type":[{"value":"1460-2350","type":"electronic"},{"value":"0268-1161","type":"print"}],"subject":[],"published-other":{"date-parts":[[2005,3]]},"published":{"date-parts":[[2005,3,1]]}}}