{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T17:32:16Z","timestamp":1772559136046,"version":"3.50.1"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,11,1]]},"DOI":"10.1093\/humrep\/dei216","type":"journal-article","created":{"date-parts":[[2005,7,30]],"date-time":"2005-07-30T00:13:36Z","timestamp":1122682416000},"page":"3072-3077","source":"Crossref","is-referenced-by-count":59,"title":["The effect of non-steroidal anti-inflammatory drugs on medical abortion with mifepristone and misoprostol at 13\u201322 weeks gestation"],"prefix":"10.1093","volume":"20","author":[{"given":"C.","family":"Fiala","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.L.","family":"Swahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Stephansson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Gemzell-Danielsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2005,7,29]]},"reference":[{"key":"key\n\t\t\t\t20171012170115_ASHOK-AND-TEMPLETON-1999","doi-asserted-by":"crossref","unstructured":"Ashok PW and Templeton A (1999) Non-surgical mid-trimester termination of pregnancy: a review of 500 consecutive cases. Br J Obstet Gynaecol106,706\u2013710.","DOI":"10.1111\/j.1471-0528.1999.tb08371.x"},{"key":"key\n\t\t\t\t20171012170115_ASHOK-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Ashok PW , Templeton A, Wagaarachchi PT and Flett GM (2004) Mid-trimester medical termination of pregnancy: a review of 1002 consecutive cases. Contraception69,51\u201358.","DOI":"10.1016\/j.contraception.2003.09.006"},{"key":"key\n\t\t\t\t20171012170115_BYGDEMAN-AND-SWAHN-1985","doi-asserted-by":"crossref","unstructured":"Bygdeman M and Swahn ML (1985) Progesterone receptor blockage. Effect on uterine contractility and early pregnancy. Contraception 32,45\u201351.","DOI":"10.1016\/0010-7824(85)90115-5"},{"key":"key\n\t\t\t\t20171012170115_CREININ-AND-SHULMAN-1997","unstructured":"Creinin M.D and Shulman T (1997) Effect of non-steroidal anti-inflammatory drugs on the action of misoprostol in a regimen for early abortion. Contraception56,165\u2013168."},{"key":"key\n\t\t\t\t20171012170115_CSAPO-1974","unstructured":"Csapo AI (1974) Prostaglandin impact inverted, question mark for menstrua induction. Popul Rep G.4,33\u201340."},{"key":"key\n\t\t\t\t20171012170115_EL-REFAEY-ET-AL-1993","doi-asserted-by":"crossref","unstructured":"El-Refaey H , Hinshaw K and Templeton A (1993) The abortifacient effect of misoprostol in the second trimester. A randomized comparison with gemeprost in patients pre-treated with mifepristone (RU 486). Hum Reprod8,1744\u20136.","DOI":"10.1093\/oxfordjournals.humrep.a137927"},{"key":"key\n\t\t\t\t20171012170115_EL-REFAEY-AND-TEMPLETON-1995","doi-asserted-by":"crossref","unstructured":"El-Refaey H and Templeton A (1995) Induction of abortion in the second trimester by a combination of misoprostol and mifepristone: a randomized comparison between two misoprostol regimens. Hum Reprod10,475\u2013478.","DOI":"10.1093\/oxfordjournals.humrep.a135965"},{"key":"key\n\t\t\t\t20171012170115_EXELGYNE-1998","unstructured":"Exelgyne SA (1998) Summary of product characteristics. Exelgyne, Paris, France."},{"key":"key\n\t\t\t\t20171012170115_FIALA-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Fiala C , Winikoff B, Helstrom L, Hellborg M and Gemzell-Danielsson K (2004) Acceptability of home-use of misoprostol in medical abortion. Contraception70,387\u2013392.","DOI":"10.1016\/j.contraception.2004.06.005"},{"key":"key\n\t\t\t\t20171012170115_GARFIELD-ET-AL-1988","unstructured":"Garfield RE , Blennerhasset MG and Miller SM (1988) Control of myometrial contractility: Role and regulation of gap junctions. In: Oxford Reviews of Reproductive Biology 10,436\u201390."},{"key":"key\n\t\t\t\t20171012170115_GEMZELL-ET-AL-1999","unstructured":"Gemzell Danielsson K , Marions L, Rodriguez A, Spur BW, Wong PY and Bygdeman M (1999) Comparison between oral and vaginal administration of misoprostol on uterine contractility. Obstet Gynecol93,275\u2013280."},{"key":"key\n\t\t\t\t20171012170115_GEMZELL-DANIELSSON-AND-OSTLUND-2000","doi-asserted-by":"crossref","unstructured":"Gemzell-Danielsson K and O\u0308stlund E (2000) Termination of second trimester pregnancy with mifepristone and gemeprost. The clinical experience of 197 consecutive cases. Acta Obstet Gynecol Scand79,702\u2013706.","DOI":"10.1080\/j.1600-0412.2000.079008702.x"},{"key":"key\n\t\t\t\t20171012170115_GORE-AND-ALTMAN-1992","unstructured":"Gore SM and Altman DG (1992) Statistics in practice. British Medical Association, London, UK, pp. 6\u20139."},{"key":"key\n\t\t\t\t20171012170115_HAMODA-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Hamoda H , Ashok PW, Flett GM and Templeton A (2004) Analgesia requirements and predictors of analgesia use for women undergoing medical abortion up to 22 weeks of gestation. BJOG111,996\u20131000.","DOI":"10.1111\/j.1471-0528.2004.00235.x"},{"key":"key\n\t\t\t\t20171012170115_HO-ET-AL-1997","doi-asserted-by":"crossref","unstructured":"Ho PC , Ngai S.W, Liu KL, Wong GC and Lee SW (1997) Vaginal misoprostol compared with oral misoprostol in termination of second-trimester pregnancy. Obstet Gynecol90,735\u2013738.","DOI":"10.1016\/S0029-7844(97)00419-5"},{"key":"key\n\t\t\t\t20171012170115_HONKANEN-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Honkanen H , Piaggio G, Hertzen H, Bartfai G, Erdenetungalag R, Gemzell-Danielsson K, Gopalan S, Horga M, Jerve F, Mittal S, et al. WHO Research Group on Post-Ovulatory Methods for Fertility Regulation (2004) WHO multinational study of three misoprostol regimens after mifepristone for early medical abortion. BJOG111,715\u2013725.","DOI":"10.1111\/j.1471-0528.2004.00153.x"},{"key":"key\n\t\t\t\t20171012170115_JAIN-ET-AL-2001","doi-asserted-by":"crossref","unstructured":"Jain JK , Harwood B, Meckstroth KR and Mishell DR (2001) Early pregnancy termination with vaginal misoprostol and acetaminophen prophylaxis. Contraception63,217\u2013221.","DOI":"10.1016\/S0010-7824(01)00193-7"},{"key":"key\n\t\t\t\t20171012170115_LI-ET-AL-2003","unstructured":"Li CFI , Wong CYG, Chan CPB and Ho PC (2003) A study of co-treatment of non-steroidal anti-inflammatory drugs (NSAIDs) with misoprostol for cervical priming before suction termination of first trimester pregnancy. Contraception67,101\u2013105."},{"key":"key\n\t\t\t\t20171012170115_LUNDSTROM-ET-AL-1976","doi-asserted-by":"crossref","unstructured":"Lundstro\u0308m V , Green K and Wiqvist N (1976) Prostaglandins, indomethacin and dysmenorrhea. Prostaglandins11,893\u2013907.","DOI":"10.1016\/0090-6980(76)90196-9"},{"key":"key\n\t\t\t\t20171012170115_NGAI-ET-AL-1999","doi-asserted-by":"crossref","unstructured":"Ngai SW , Chan YM, Tang OS and Ho PC (1999) The use of misoprostol for pre-operative cervical dilatation prior to vacuum aspiration: a randomized trial. Hum Reprod14,2139\u20132142.","DOI":"10.1093\/humrep\/14.8.2139"},{"key":"key\n\t\t\t\t20171012170115_NORMAN-ET-AL-1991","doi-asserted-by":"crossref","unstructured":"Norman JE , Kelly RW and Baird DT (1991) Uterine activity and decidual prostaglandin production in women in early pregnancy in response to mifepristone with or without indomethacin in vivo. Hum Reprod6,740\u2013744.","DOI":"10.1093\/oxfordjournals.humrep.a137420"},{"key":"key\n\t\t\t\t20171012170115_OLUND-1979","doi-asserted-by":"crossref","unstructured":"O\u0308lund A (1979) The effect of indomethacin on the instillation-abortion interval in rivanol-induced mid-trimester abortion. Acta Obstet Gynecol Scand58,121\u2013122.","DOI":"10.3109\/00016347909154928"},{"key":"key\n\t\t\t\t20171012170115_RADESTAD-AND-BYGDEMAN-1992","unstructured":"Ra\u030adestad A and Bygdeman M (1992) Cervical softening with mifepristone (RU 486) after pretreatment with naproxen. A double-blind randomized study. Contraception45,221\u2013227."},{"key":"key\n\t\t\t\t20171012170115_RADESTAD-ET-AL-1993","doi-asserted-by":"crossref","unstructured":"Ra\u030adestad A , Thyberg J and Christensen NJ (1993) Cervical ripening with mifepristone (RU 486) in first trimester abortion. An electron microscope study. Hum Reprod8,1136\u20131142.","DOI":"10.1093\/oxfordjournals.humrep.a138207"},{"key":"key\n\t\t\t\t20171012170115_SMITH-1987","unstructured":"Smith RP (1987) The dynamics of nonsteroidal anti-inflammatory therapy for primary dysmenorrhoea. Obstet Gynecol70,785\u2013788."},{"key":"key\n\t\t\t\t20171012170115_SPITZ-ET-AL-1998","doi-asserted-by":"crossref","unstructured":"Spitz IM , Bardin CW, Benton L and Robbins A (1998) Early pregnancy termination with mifepristone and misoprostol in the United States. N Engl J Med338,1241\u20131247.","DOI":"10.1056\/NEJM199804303381801"},{"key":"key\n\t\t\t\t20171012170115_WESTHOFF-ET-AL-2000A","doi-asserted-by":"crossref","unstructured":"Westhoff C , Dasmahapatra R, Winikoff B and Clarke S. Mifepristone Clinical Trials Group. (2000a) Predictors of analgesia use during supervised medical abortion. Contraception61,225\u2013229.","DOI":"10.1016\/S0010-7824(00)00090-1"},{"key":"key\n\t\t\t\t20171012170115_WESTHOFF-ET-AL-2000B","doi-asserted-by":"crossref","unstructured":"Westhoff C , Dasmahapatra R and Schaff E (2000b) Analgesia during at-home use of misoprostol as part of a medical abortion regimen. Contraception62,311\u2013314.","DOI":"10.1016\/S0010-7824(00)00186-4"},{"key":"key\n\t\t\t\t20171012170115_WIEBE-2001","doi-asserted-by":"crossref","unstructured":"Wiebe ER (2001) Pain control in medical abortion. Int J Gynecol Obstet74,275\u2013280.","DOI":"10.1016\/S0020-7292(01)00453-2"},{"key":"key\n\t\t\t\t20171012170115_ZIEMAN-ET-AL-1997","doi-asserted-by":"crossref","unstructured":"Zieman M , Fong SK, Benowitz NL, Banskter D and Darney PD (1997) Absorption kinetics of misoprostol with oral or vagina administration. Obstet Gynecol90,88\u201392.","DOI":"10.1016\/S0029-7844(97)00111-7"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/20\/11\/3072\/9543676\/dei216.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T12:28:46Z","timestamp":1586348926000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/humrep\/article\/20\/11\/3072\/2913824\/The-effect-of-nonsteroidal-antiinflammatory-drugs"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7,29]]},"references-count":30,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2005,7,29]]},"published-print":{"date-parts":[[2005,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/dei216","relation":{},"ISSN":["1460-2350","0268-1161"],"issn-type":[{"value":"1460-2350","type":"electronic"},{"value":"0268-1161","type":"print"}],"subject":[],"published-other":{"date-parts":[[2005,11]]},"published":{"date-parts":[[2005,7,29]]}}}