{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:25:12Z","timestamp":1790702712836,"version":"4.1.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,12,1]]},"DOI":"10.1093\/humrep\/dei261","type":"journal-article","created":{"date-parts":[[2005,8,26]],"date-time":"2005-08-26T00:24:07Z","timestamp":1125015847000},"page":"3360-3368","source":"Crossref","is-referenced-by-count":89,"title":["Expression of \u03b2-subunit of HCG genes during normal and failed pregnancy"],"prefix":"10.1093","volume":"20","author":[{"given":"Kristiina","family":"Rull","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maris","family":"Laan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2005,8,25]]},"reference":[{"key":"key\n\t\t\t\t20171012113457_BELLET-ET-AL-1997","unstructured":"Bellet D , Lazar V, Bieche I, Paradis V, Giovangrandi Y, Paterlini P, Lidereau R, Bedossa P, Bidart JM and Vidaud M (1997) Malignant transformation of nontrophoblastic cells is associated with the expression of chorionic gonadotropin beta genes normally transcribed in trophoblastic cells. Cancer Res57,516\u2013523."},{"key":"key\n\t\t\t\t20171012113457_BIECHE-ET-AL-1998","unstructured":"Bieche I , Lazar V, Nogues C, Poynard T, Giovangrandi Y, Bellet D, Lidereau R and Vidaud M (1998) Prognostic value of chorionic gonadotropin beta gene transcripts in human breast carcinoma. Clin Cancer Res4,671\u2013676."},{"key":"key\n\t\t\t\t20171012113457_BO-AND-BOIME-1992","doi-asserted-by":"crossref","unstructured":"Bo M and Boime I (1992) Identification of the transcriptionally active genes of the chorionic gonadotropin beta gene cluster in vivo. J Biol Chem267,3179\u20133184.","DOI":"10.1016\/S0021-9258(19)50712-8"},{"key":"key\n\t\t\t\t20171012113457_BUYALOS-ET-AL-1992","unstructured":"Buyalos RP , Glassman LM, Rifka SM, Falk RJ, Macarthy PO, Tyson VJ and DiMattina M (1992) Serum beta-human chorionic gonadotropin, estradiol and progesterone as early predictors of pathologic pregnancy. J Reprod Med37,261\u2013266."},{"key":"key\n\t\t\t\t20171012113457_DAWOOD-ET-AL-1977","unstructured":"Dawood MY , Saxena BB and Landesman R (1977) Human chorionic gonadotropin and its subunits in hydatidiform mole and choriocarcinoma. Obstet Gynecol50,172\u2013181."},{"key":"key\n\t\t\t\t20171012113457_DIRNHOFER-ET-AL-1996","unstructured":"Dirnhofer S , Hermann M, Hittmair A, Hoermann R, Kapelari K and Berger P (1996) Expression of the human chorionic gonadotropin-beta gene cluster in human pituitaries and alternate use of exon 1. J Clin Endocrinol Metab81,4212\u20134217."},{"key":"key\n\t\t\t\t20171012113457_FRITZ-ET-AL-2001","doi-asserted-by":"crossref","unstructured":"Fritz B , Hallermann C, Olert J, Fuchs B, Bruns M, Aslan M, Schmidt S, Coerdt W, Muntefering H and Rehder H (2001) Cytogenetic analyses of culture failures by comparative genomic hybridisation (CGH)\u2014re-evaluation of chromosome aberration rates in early spontaneous abortions. Eur J Hum Genet9,539\u2013547.","DOI":"10.1038\/sj.ejhg.5200669"},{"key":"key\n\t\t\t\t20171012113457_GASPARD-ET-AL-1980","doi-asserted-by":"crossref","unstructured":"Gaspard UJ , Reuter AM, Deville JL, Vrindts-Gevaert Y, Bagshawe KD and Franchimont P (1980) Serum concentration of human chorionic gonadotropin and its alpha and beta subunits. 2. Trophoblastic tumours. Clin Endocrinol (Oxf)13,319\u2013329.","DOI":"10.1111\/j.1365-2265.1980.tb03391.x"},{"key":"key\n\t\t\t\t20171012113457_GERHARD-AND-RUNNEBAUM-1984","doi-asserted-by":"crossref","unstructured":"Gerhard I and Runnebaum B (1984) Predictive value of hormone determinations in the first half of pregnancy. Eur J Obstet Gynecol Reprod Biol17,1\u201317.","DOI":"10.1016\/0028-2243(84)90075-3"},{"key":"key\n\t\t\t\t20171012113457_GIOVANGRANDI-ET-AL-2001","doi-asserted-by":"crossref","unstructured":"Giovangrandi Y , Parfait B, Asheuer M, Olivi M, Lidereau R, Vidaud M and Bieche I (2001) Analysis of the human CGB\/LHB gene cluster in breast tumors by real-time quantitative RT\u2013PCR assays. Cancer Lett168,93\u2013100.","DOI":"10.1016\/S0304-3835(01)00496-7"},{"key":"key\n\t\t\t\t20171012113457_HAY-1988","doi-asserted-by":"crossref","unstructured":"Hay DL (1988) Placental histology and the production of human choriogonadotrophin and its subunits in pregnancy. Br J Obstet Gynaecol95,1268\u20131275.","DOI":"10.1111\/j.1471-0528.1988.tb06817.x"},{"key":"key\n\t\t\t\t20171012113457_HOTAKAINEN-ET-AL-2002","doi-asserted-by":"crossref","unstructured":"Hotakainen K , Ljungberg B, Paju A, Rasmuson T, Alfthan H and Stenman UH (2002) The free beta-subunit of human chorionic gonadotropin as a prognostic factor in renal cell carcinoma. Br J Cancer86,185\u2013189.","DOI":"10.1038\/sj.bjc.6600050"},{"key":"key\n\t\t\t\t20171012113457_JURISICOVA-ET-AL-1999","doi-asserted-by":"crossref","unstructured":"Jurisicova A , Antenos M, Kapasi K, Meriano J and Casper RF (1999) Variability in the expression of trophectodermal markers beta-human chorionic gonadotrophin, human leukocyte antigen-G and pregnancy specific beta-1 glycoprotein by the human blastocyst. Hum Reprod14,1852\u20131858.","DOI":"10.1093\/humrep\/14.7.1852"},{"key":"key\n\t\t\t\t20171012113457_KNOFLER-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Knofler M , Saleh L, Bauer S, Galos B, Rotheneder H, Husslein P and Helmer H (2004) Transcriptional regulation of the human chorionic gonadotropin beta gene during villous trophoblast differentiation. Endocrinology145,1685\u20131694.","DOI":"10.1210\/en.2003-0954"},{"key":"key\n\t\t\t\t20171012113457_LAZAR-ET-AL-1995","unstructured":"Lazar V , Diez SG, Laurent A, Giovangrandi Y, Radvanyi F, Chopin D, Bidart JM, Bellet D and Vidaud M (1995) Expression of human chorionic gonadotropin beta subunit genes in superficial and invasive bladder carcinomas. Cancer Res55,3735\u20133738."},{"key":"key\n\t\t\t\t20171012113457_LETTERIE-AND-HIBBERT-2000","doi-asserted-by":"crossref","unstructured":"Letterie GS and Hibbert M (2000) Serial serum human chorionic gonadotropin (hCG) levels in ectopic pregnancy and first trimester miscarriage. Arch Gynecol Obstet263,168\u2013169.","DOI":"10.1007\/s004040050275"},{"key":"key\n\t\t\t\t20171012113457_LYALL-2002","doi-asserted-by":"crossref","unstructured":"Lyall F (2002) The human placental bed revisited. Placenta23,555\u2013562.","DOI":"10.1053\/plac.2002.0850"},{"key":"key\n\t\t\t\t20171012113457_MARUO-ET-AL-1992","doi-asserted-by":"crossref","unstructured":"Maruo T , Ladines-Llave CA, Matsuo H, Manalo AS and Mochizuki M (1992) A novel change in cytologic localization of human chorionic gonadotropin and human placental lactogen in first-trimester placenta in the course of gestation. Am J Obstet Gynecol167,217\u2013222.","DOI":"10.1016\/S0002-9378(11)91661-5"},{"key":"key\n\t\t\t\t20171012113457_MEEGDES-ET-AL-1988","doi-asserted-by":"crossref","unstructured":"Meegdes BH , Ingenhoes R, Peeters LL and Exalto N (1988) Early pregnancy wastage: relationship between chorionic vascularization and embryonic development. Fertil Steril49,216\u2013220.","DOI":"10.1016\/S0015-0282(16)59704-0"},{"key":"key\n\t\t\t\t20171012113457_MILLER-LINDHOLM-ET-AL-1997","doi-asserted-by":"crossref","unstructured":"Miller-Lindholm AK , LaBenz CJ, Ramey J, Bedows E and Ruddon RW (1997) Human chorionic gonadotropin-beta gene expression in first trimester placenta. Endocrinology138,5459\u20135465.","DOI":"10.1210\/endo.138.12.5618"},{"key":"key\n\t\t\t\t20171012113457_POIKKEUS-ET-AL-2002","doi-asserted-by":"crossref","unstructured":"Poikkeus P , Hiilesmaa V and Tiitinen A (2002) Serum HCG 12 days after embryo transfer in predicting pregnancy outcome. Hum Reprod17,1901\u20131905.","DOI":"10.1093\/humrep\/17.7.1901"},{"key":"key\n\t\t\t\t20171012113457_RADONIC-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Radonic A , Thulke S, Mackay IM, Landt O, Siegert W and Nitsche A (2004) Guideline to reference gene selection for quantitative real-time PCR. Biochem Biophys Res Commun313,856\u2013862.","DOI":"10.1016\/j.bbrc.2003.11.177"},{"key":"key\n\t\t\t\t20171012113457_RANDALL-ET-AL-1987","doi-asserted-by":"crossref","unstructured":"Randall S , Buckley CH and Fox H (1987) Placentation in the fallopian tube. Int J Gynecol Pathol6,132\u2013139.","DOI":"10.1097\/00004347-198706000-00005"},{"key":"key\n\t\t\t\t20171012113457_RAO-2001","unstructured":"Rao CV (2001) Tropic effects of LH and hCG on early pregnancy events in women\u2019s reproductive tract. Early Pregn5,18\u201319."},{"key":"key\n\t\t\t\t20171012113457_SPAN-ET-AL-2002","doi-asserted-by":"crossref","unstructured":"Span PN , Thomas CM, Heuvel JJ, Bosch RR, Schalken JA, vd Locht L, Mensink EJ and Sweep CG (2002) Analysis of expression of chorionic gonadotrophin transcripts in prostate cancer by quantitative Taqman and a modified molecular beacon RT-PCR. J Endocrinol172,489\u2013495.","DOI":"10.1677\/joe.0.1720489"},{"key":"key\n\t\t\t\t20171012113457_SPAN-ET-AL-2003","doi-asserted-by":"crossref","unstructured":"Span PN , Manders P, Heuvel JJ, Thomas CM, Bosch RR, Beex LV and Sweep CG (2003) Molecular beacon reverse transcription\u2013PCR of human chorionic gonadotropin-beta-3, -5 and -8 mRNAs has prognostic value in breast cancer. Clin Chem49,1074\u20131080.","DOI":"10.1373\/49.7.1074"},{"key":"key\n\t\t\t\t20171012113457_SRISUPARP-ET-AL-2001","doi-asserted-by":"crossref","unstructured":"Srisuparp S , Strakova Z and Fazleabas AT (2001) The role of chorionic gonadotropin (CG) in blastocyst implantation. Arch Med Res32,627\u2013634.","DOI":"10.1016\/S0188-4409(01)00330-7"},{"key":"key\n\t\t\t\t20171012113457_STENMAN-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Stenman UH , Alfthan H and Hotakainen K (2004) Human chorionic gonadotropin in cancer. Clin Biochem37,549\u2013561.","DOI":"10.1016\/j.clinbiochem.2004.05.008"},{"key":"key\n\t\t\t\t20171012113457_TALMADGE-ET-AL-1984","doi-asserted-by":"crossref","unstructured":"Talmadge K , Vamvakopoulos NC and Fiddes JC (1984) Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone. Nature307,37\u201340.","DOI":"10.1038\/307037a0"},{"key":"key\n\t\t\t\t20171012113457_TOTH-ET-AL-2001","unstructured":"Toth P , Lukacs H, Gimes G, Sebestyen A, Pasztor N, Paulin F and Rao CV (2001) Clinical importance of vascular LH\/hCG receptors\u2014a review. Reprod Biol1,5\u201311."},{"key":"key\n\t\t\t\t20171012113457_WILLEY-1999","doi-asserted-by":"crossref","unstructured":"Willey KP (1999) An elusive role for glycosylation in the structure and function of reproductive hormones. Hum Reprod Update5,330\u2013355.","DOI":"10.1093\/humupd\/5.4.330"},{"key":"key\n\t\t\t\t20171012113457_ZYGMUNT-ET-AL-2002","doi-asserted-by":"crossref","unstructured":"Zygmunt M , Herr F, Keller-Schoenwetter S, Kunzi-Rapp K, Munstedt K, Rao CV, Lang U and Preissner KT (2002) Characterization of human chorionic gonadotropin as a novel angiogenic factor. J Clin Endocrinol Metab87,5290\u20135296.","DOI":"10.1210\/jc.2002-020642"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/20\/12\/3360\/9543529\/dei261.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T19:31:28Z","timestamp":1626463888000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/humrep\/article\/20\/12\/3360\/2913788\/Expression-of-\u03b2subunit-of-HCG-genes-during-normal"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8,25]]},"references-count":32,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2005,8,25]]},"published-print":{"date-parts":[[2005,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/dei261","relation":{},"ISSN":["1460-2350","0268-1161"],"issn-type":[{"value":"1460-2350","type":"electronic"},{"value":"0268-1161","type":"print"}],"subject":[],"published-other":{"date-parts":[[2005,12]]},"published":{"date-parts":[[2005,8,25]]}}}