{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T21:05:01Z","timestamp":1789247101258,"version":"build-2803163510"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,4,1]]},"DOI":"10.1093\/humrep\/dei428","type":"journal-article","created":{"date-parts":[[2005,12,23]],"date-time":"2005-12-23T01:33:45Z","timestamp":1135301625000},"page":"980-985","source":"Crossref","is-referenced-by-count":30,"title":["Reduced recombination associated with the production of aneuploid sperm in an infertile man: a case report"],"prefix":"10.1093","volume":"21","author":[{"given":"S.","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.A.","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Arsovska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Moens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2005,12,22]]},"reference":[{"key":"key\n\t\t\t\t20171012080622_BARLOW-AND-HULTEN-1998","doi-asserted-by":"crossref","unstructured":"Barlow AL and Hulten MA (1998) Crossing over analysis at pachytene in man. Eur J Hum Genet6,350\u2013358.","DOI":"10.1038\/sj.ejhg.5200200"},{"key":"key\n\t\t\t\t20171012080622_BERNARDINI-ET-AL-2000","doi-asserted-by":"crossref","unstructured":"Bernardini L , Gianaroli L, Fortini D, Conte N, Magli C, Cayani S, Gaggero G, Tindiglia C, Ragni N and Venturini PL (2000) Frequency of hyper- and hypohaploidy and diploidy in ejaculate, epididymal and testicular germ cells of infertile patients. Hum Reprod15,2165\u20132172.","DOI":"10.1093\/humrep\/15.10.2165"},{"key":"key\n\t\t\t\t20171012080622_BONDUELLE-ET-AL-2002","doi-asserted-by":"crossref","unstructured":"Bonduelle M , Van Assche E, Joris H, Keymolen K, Devroey P, Van Streirteghem A and Liebaers I (2002) Prenatal testing in ICSI pregnancies: incidence of chromosomal anomalies in 1586 karyotypes and relations with abnormal semen parameters. Hum Reprod17,2600\u20132614.","DOI":"10.1093\/humrep\/17.10.2600"},{"key":"key\n\t\t\t\t20171012080622_CODINA-PASCUAL-ET-AL-2005","doi-asserted-by":"crossref","unstructured":"Codina-Pascual M , Oliver-Bonet M, Navarro J, Campillo M, Garcia F, Egozcue S, Abad C, Egozcue J and Benet J (2005) Synapsis and meiotic recombination analyses: MLH1 focus in the XY pair as an indicator. Hum Reprod20,2133\u20132139.","DOI":"10.1093\/humrep\/dei023"},{"key":"key\n\t\t\t\t20171012080622_GIANAROLI-ET-AL-2005","doi-asserted-by":"crossref","unstructured":"Gianaroli L , Magli MC, Cavallini G, Crippa A, Nadalini M, Bernardini L, Menchini Fabris GF, Voliani S and Ferraretti AP (2005) Frequency of aneuploidy in sperm from patients with extremely severe male factor infertility. Hum Reprod20,2140\u20132152.","DOI":"10.1093\/humrep\/dei033"},{"key":"key\n\t\t\t\t20171012080622_GONSALVES-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Gonsalves J , Sun F, Schlegel PN, Turek PJ, Hopps CV, Greene C, Martin R and Reijo Pera RA (2004) Defective recombination in infertile men. Hum Mol Genet13,2875\u20132883.","DOI":"10.1093\/hmg\/ddh302"},{"key":"key\n\t\t\t\t20171012080622_HALE-1994","doi-asserted-by":"crossref","unstructured":"Hale DW (1994) Is X-Y recombination necessary for spermatocyte survival during mammalian spermatogenesis? Cytogenet Cell Genet65,278\u2013282.","DOI":"10.1159\/000133648"},{"key":"key\n\t\t\t\t20171012080622_HASSOLD-AND-HUNT-2001","doi-asserted-by":"crossref","unstructured":"Hassold TJ and Hunt P (2001) To err (meiotically) is human: the genesis of human aneuploidy. Nat Rev Genet2,280\u2013291.","DOI":"10.1038\/35066065"},{"key":"key\n\t\t\t\t20171012080622_HASSOLD-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Hassold T , Judis L, Chan ER, Schwartz S, Seftel A and Lynn A (2004) Cytological studies of meiotic recombination in human males. Cytogenet Genome Res107,249\u2013255.","DOI":"10.1159\/000080602"},{"key":"key\n\t\t\t\t20171012080622_HASSOLD-ET-AL-2000","doi-asserted-by":"crossref","unstructured":"Hassold TJ , Sherman S and Hunt P (2000) Counting cross-over: characterizing meiotic recombination in mammals. Hum Mol Genet9,2409\u20132419.","DOI":"10.1093\/hmg\/9.16.2409"},{"key":"key\n\t\t\t\t20171012080622_HASSOLD-ET-AL-1991","unstructured":"Hassold TJ , Sherman SL, Pettay D, Page DC and Jacobs PA (1991) XY chromosome nondisjunction in man is associated with diminished recombination in the pseudoautosomal region. Am J Hum Genet49,253\u2013260."},{"key":"key\n\t\t\t\t20171012080622_JUDIS-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Judis L , Chan ER, Schwartz S, Seftel A and Hassold TJ (2004) Meiosis I arrest and azoospermia in an infertile man explained by failure of formation of a component of the synaptonemal complex. Fertil Steril74,205\u2013209.","DOI":"10.1016\/j.fertnstert.2003.05.021"},{"key":"key\n\t\t\t\t20171012080622_LYNN-ET-AL-2002","doi-asserted-by":"crossref","unstructured":"Lynn A , Koehler KE, Judis L, Chan ER, Cherry JP, Schwartz S, Seftel A, Hunt PA and Hassold TJ (2002) Covariation of synaptonemal complex length and mammalian meiotic exchange rates. Science296,2222\u20132225.","DOI":"10.1126\/science.1071220"},{"key":"key\n\t\t\t\t20171012080622_MARCON-AND-MOENS-2003","doi-asserted-by":"crossref","unstructured":"Marcon E and Moens P (2003) MLH1p and MLH3p localize to precociously induced chiasmata of okadaic-acid-treated mouse spermatocytes. Genetics165,2283\u20132287.","DOI":"10.1093\/genetics\/165.4.2283"},{"key":"key\n\t\t\t\t20171012080622_MOENS-ET-AL-2002","doi-asserted-by":"crossref","unstructured":"Moens PB , Kolas NK, Tarsounas M, Marcon E, Cohen PE and Spyropoulos B (2002) The time course of chromosomal localization of recombination-related proteins at meiosis in the mouse are compatible with models that can resolve the early DNA\u2013DNA interactions without reciprocal recombination. J Cell Sci115,1611\u20131622.","DOI":"10.1242\/jcs.115.8.1611"},{"key":"key\n\t\t\t\t20171012080622_MOOSANI-ET-AL-1995","doi-asserted-by":"crossref","unstructured":"Moosani N , Pattinson HA, Carter MD, Cox DM, Rademaker AW and Martin RH (1995) Chromosomal analysis of sperm from men with idiopathic infertility using sperm karyotyping and fluorescent in situ hybridization. Fertil Steril64,811\u2013817.","DOI":"10.1016\/S0015-0282(16)57859-5"},{"key":"key\n\t\t\t\t20171012080622_OLIVER-BONET-ET-AL-2003","doi-asserted-by":"crossref","unstructured":"Oliver-Bonet M , Lieh T, Nietzel A, Heller A, Starke H, Claussen U, Codina-Pascual M, Pujol A, Abad C, Egozcue J, Navarro J and Benet J (2003) Karyotyping of human synaptonemal complexes by cenM-FISH. Am J Hum Genet11,879\u2013883.","DOI":"10.1038\/sj.ejhg.5201067"},{"key":"key\n\t\t\t\t20171012080622_ROEDER-1997","doi-asserted-by":"crossref","unstructured":"Roeder GS (1997) Meiotic chromosomes: it takes two to tango. Genes Dev11,2600\u20132621.","DOI":"10.1101\/gad.11.20.2600"},{"key":"key\n\t\t\t\t20171012080622_SAVAGE-ET-AL-1998","doi-asserted-by":"crossref","unstructured":"Savage AR , Petersen MB, Pettay D, Taft L, Allran K, Freeman SB, Karadima G, Avramopoulos D, Torfs C, Mikkelsen M, Hassold TJ and Sherman SL (1998) Elucidating the mechanism of paternal non-disjunction of chromosome 21 in humans. Hum Mol Genet7,1221\u20131227.","DOI":"10.1093\/hmg\/7.8.1221"},{"key":"key\n\t\t\t\t20171012080622_SHERMAN-ET-AL-1991","unstructured":"Sherman SL , Takaesu N, Freeman SB, Grantham M, Phillips C, Blackston RD, Jacobs PA, Cockwell AE, Freeman V, Uchida I, Mikkelson M, Kurnit DM, Buraczynska M, Keats BJB and Hassold TJ (1991) Trisomy 21: association between reduced recombination and nondisjunction. Am J Hum Genet49,608\u2013620."},{"key":"key\n\t\t\t\t20171012080622_SHI-ET-AL-2001","doi-asserted-by":"crossref","unstructured":"Shi Q , Spriggs E, Field LL, Ko E, Barclay L and Martin RH (2001) Single sperm typing demonstrates that reduced recombination is associated with the production of aneuploid 24,XY human sperm. Am J Med Genet99,34\u201338.","DOI":"10.1002\/1096-8628(20010215)99:1<34::AID-AJMG1106>3.0.CO;2-D"},{"key":"key\n\t\t\t\t20171012080622_SUN-ET-AL-2004A","doi-asserted-by":"crossref","unstructured":"Sun F , Kozak G, Scott S, Trpkov K, Ko E, Mikhaail-Phillips M, Bestor TH, Moens P and Martin R (2004) Meiotic defects in a man with non-obstructive azoospermia: case report. Hum Reprod19,1770\u20131773.","DOI":"10.1093\/humrep\/deh335"},{"key":"key\n\t\t\t\t20171012080622_SUN-ET-AL-2004B","doi-asserted-by":"crossref","unstructured":"Sun F , Oliver-Bonet M, Lieh T, Starke H, Ko E, Rademaker A, Navarro J, Benet J and Martin R (2004) Human male recombination maps for individual chromosomes. Am J Hum Genet74,521\u2013531.","DOI":"10.1086\/382138"},{"key":"key\n\t\t\t\t20171012080622_SUN-ET-AL-2005","doi-asserted-by":"crossref","unstructured":"Sun F , Trypkov K, Rademaker A, Ko E and Martin RH (2005) Variation in meiotic recombination frequencies among human males. Hum Genet116,172\u2013178.","DOI":"10.1007\/s00439-004-1215-6"},{"key":"key\n\t\t\t\t20171012080622_TANG-ET-AL-2004","doi-asserted-by":"crossref","unstructured":"Tang SS , Gao H, Robinson WP, Ho Yuen B and Ma S (2004) An association between sex chromosomal aneuploidy in sperm and an abortus with 45,X of paternal origin: possible transmission of chromosomal abnormalities through ICSI. Hum Reprod19,147\u2013151.","DOI":"10.1093\/humrep\/deh007"},{"key":"key\n\t\t\t\t20171012080622_THOMAS-ET-AL-2000","doi-asserted-by":"crossref","unstructured":"Thomas NS , Collins AR, Hassold TJ and Jacobs PJ (2000) A reinvestigation of non-disjunction resulting in 47,XXY males of paternal origin. Eur J Hum Genet8,805\u2013808.","DOI":"10.1038\/sj.ejhg.5200531"},{"key":"key\n\t\t\t\t20171012080622_USHIJIMA-ET-AL-2000","doi-asserted-by":"crossref","unstructured":"Ushijima C , Kumasako Y, Kihaile PE, Hirotsuru K and Utsunomiya T (2000) Analysis of chromosomal abnormalities in human spermatozoa using multi-colour fluorescent in-situ hybridization. Hum Reprod15,1107\u20131111.","DOI":"10.1093\/humrep\/15.5.1107"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/21\/4\/980\/1574062\/dei428.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T23:17:02Z","timestamp":1626909422000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/humrep\/article\/21\/4\/980\/585567\/Reduced-recombination-associated-with-the"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12,22]]},"references-count":27,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2005,12,22]]},"published-print":{"date-parts":[[2006,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/dei428","relation":{},"ISSN":["1460-2350","0268-1161"],"issn-type":[{"value":"1460-2350","type":"electronic"},{"value":"0268-1161","type":"print"}],"subject":[],"published-other":{"date-parts":[[2006,4]]},"published":{"date-parts":[[2005,12,22]]}}}