{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T11:37:19Z","timestamp":1777549039176,"version":"3.51.4"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Reproduction"],"published-print":{"date-parts":[[2009,8,1]]},"DOI":"10.1093\/humrep\/dep113","type":"journal-article","created":{"date-parts":[[2009,4,29]],"date-time":"2009-04-29T20:25:51Z","timestamp":1241036751000},"page":"2014-2022","source":"Crossref","is-referenced-by-count":108,"title":["Genetic polymorphisms of GnRH and gonadotrophic hormone receptors affect the phenotype of polycystic ovary syndrome"],"prefix":"10.1093","volume":"24","author":[{"given":"O.","family":"Valkenburg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.G.","family":"Uitterlinden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Piersma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Hofman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.P.N.","family":"Themmen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.H.","family":"de Jong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.C.J.M.","family":"Fauser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.S.E.","family":"Laven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2009,4,29]]},"reference":[{"issue":"2","key":"1_16036359","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/0303-7207(95)03557-N","volume":"111","author":"Atger","year":"1995","journal-title":"Molecular and cellular endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0303-7207","issn-type":"print"},{"issue":"6","key":"2_18211987","doi-asserted-by":"publisher","first-page":"2745","DOI":"10.1210\/jc.2003-032046","volume":"89","author":"Azziz","year":"2004","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"6","key":"3_17989298","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1093\/humupd\/dmg044","volume":"9","author":"Balen","year":"2003","journal-title":"Human Reproduction Update","ISSN":"https:\/\/id.crossref.org\/issn\/1355-4786","issn-type":"print"},{"issue":"7","key":"4_18944072","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1097\/01.fpc.0000167330.92786.5e","volume":"15","author":"Behre","year":"2005","ISSN":"https:\/\/id.crossref.org\/issn\/1744-6872","issn-type":"print"},{"issue":"5","key":"5_18842379","doi-asserted-by":"publisher","first-page":"2810","DOI":"10.1210\/jc.2004-2359","volume":"90","year":"2005","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"2","key":"6_5328447","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1210\/endo-125-2-917","volume":"125","author":"DALKIN","year":"1989","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"4","key":"7_9589749","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1007\/BF00145007","volume":"7","author":"Hofman","year":"1991","journal-title":"European journal of epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0393-2990","issn-type":"print"},{"issue":"11","key":"8_29857020","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1007\/s10654-007-9199-x","volume":"22","author":"Hofman","year":"2007","journal-title":"European journal of epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0393-2990","issn-type":"print"},{"issue":"7","key":"9_6075043","doi-asserted-by":"publisher","first-page":"2361","DOI":"10.1210\/jc.83.7.2361","volume":"83","author":"Imani","year":"1998","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"key":"10_34696013","first-page":"185","volume":"32","year":"2003","ISSN":"https:\/\/id.crossref.org\/issn\/1873-2763","issn-type":"print"},{"issue":"3","key":"11_11062146","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1210\/jc.86.3.1318","volume":"86","author":"Jakimiuk","year":"2001","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"11","key":"12_17346178","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1097\/00006254-200211000-00022","volume":"57","author":"Laven","year":"2002","journal-title":"Obstetrical & gynecological survey","ISSN":"https:\/\/id.crossref.org\/issn\/0029-7828","issn-type":"print"},{"issue":"4","key":"13_17856151","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1016\/S0015-0282(03)01115-4","volume":"80","author":"Laven","year":"2003","journal-title":"Fertility and sterility","ISSN":"https:\/\/id.crossref.org\/issn\/0015-0282","issn-type":"print"},{"issue":"9","key":"14_10481291","doi-asserted-by":"publisher","first-page":"3365","DOI":"10.1210\/jc.85.9.3365","volume":"85","author":"Mayorga","year":"2000","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"4","key":"15_21588620","doi-asserted-by":"publisher","first-page":"1470","DOI":"10.1210\/jc.2005-2156","volume":"91","year":"2006","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"4","key":"16_29259409","doi-asserted-by":"publisher","first-page":"R51","DOI":"10.1186\/bcr1756","volume":"9","author":"Piersma","year":"2007","journal-title":"Breast cancer research : BCR","ISSN":"https:\/\/id.crossref.org\/issn\/1465-5411","issn-type":"print"},{"issue":"1-2","key":"17_29389417","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.mce.2007.06.007","volume":"276","author":"Piersma","year":"2007","journal-title":"Molecular and cellular endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0303-7207","issn-type":"print"},{"issue":"4","key":"18_17572525","doi-asserted-by":"publisher","first-page":"1653","DOI":"10.1210\/jc.2002-021585","volume":"88","author":"Powell","year":"2003","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"1","key":"19_17987236","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.fertnstert.2003.10.004","volume":"81","year":"2004","journal-title":"Fertility and sterility","ISSN":"https:\/\/id.crossref.org\/issn\/0015-0282","issn-type":"print"},{"issue":"6","key":"20_6099676","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.1093\/humrep\/13.6.1442","volume":"13","author":"Schipper","year":"1998","journal-title":"Human Reproduction","ISSN":"https:\/\/id.crossref.org\/issn\/0268-1161","issn-type":"print"},{"issue":"2","key":"21_18689903","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1210\/jc.2004-0649","volume":"90","year":"2005","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"2","key":"22_10728100","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1210\/jc.84.2.751","volume":"84","author":"Simoni","year":"1999","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"5","key":"23_17298612","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1093\/humupd\/8.5.413","volume":"8","author":"Simoni","year":"2002","journal-title":"Human Reproduction Update","ISSN":"https:\/\/id.crossref.org\/issn\/1355-4786","issn-type":"print"},{"issue":"5","key":"24_31422033","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1093\/humupd\/dmn024","volume":"14","year":"2008","journal-title":"Human Reproduction Update","ISSN":"https:\/\/id.crossref.org\/issn\/1355-4786","issn-type":"print"},{"issue":"3","key":"25_30543845","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1097\/FPC.0b013e3282f4e98c","volume":"18","author":"Simoni","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1744-6872","issn-type":"print"},{"issue":"7","key":"26_4822888","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1210\/mend-1-7-465","volume":"1","author":"Steinkampf","year":"1987","journal-title":"Molecular Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0888-8809","issn-type":"print"},{"issue":"4","key":"27_11073876","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1086\/319501","volume":"68","author":"Stephens","year":"2001","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"6","key":"28_21263747","doi-asserted-by":"publisher","first-page":"1762","DOI":"10.1016\/j.fertnstert.2005.06.031","volume":"84","author":"Vagenakis","year":"2005","journal-title":"Fertility and sterility","ISSN":"https:\/\/id.crossref.org\/issn\/0015-0282","issn-type":"print"},{"issue":"3","key":"29_16704813","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/S0015-0282(97)80068-4","volume":"67","author":"van Santbrink","year":"1997","journal-title":"Fertility and sterility","ISSN":"https:\/\/id.crossref.org\/issn\/0015-0282","issn-type":"print"},{"issue":"4","key":"30_9765940","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1210\/jc.74.4.836","volume":"74","author":"Venturoli","year":"1992","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"16","key":"31_19309673","doi-asserted-by":"publisher","first-page":"3445","DOI":"10.1093\/bioinformatics\/bti529","volume":"21","year":"2005","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"5","key":"32_18775046","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1086\/429864","volume":"76","author":"Wigginton","year":"2005","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"4","key":"33_11513894","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1210\/jcem-30-4-435","volume":"30","author":"YEN","year":"1970","journal-title":"Journal of Clinical Endocrinology & Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"20","key":"34_13016937","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1056\/NEJM198311173092002","volume":"309","author":"Zumoff","year":"1983","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/24\/8\/2014\/1832180\/dep113.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T17:53:37Z","timestamp":1550598817000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humrep\/article-lookup\/doi\/10.1093\/humrep\/dep113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,29]]},"references-count":34,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2009,7,14]]},"published-print":{"date-parts":[[2009,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/dep113","relation":{},"ISSN":["0268-1161","1460-2350"],"issn-type":[{"value":"0268-1161","type":"print"},{"value":"1460-2350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,29]]}}}