{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:23:28Z","timestamp":1791181408017,"version":"4.1.0"},"reference-count":46,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1093\/humrep\/des360","type":"journal-article","created":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:38:44Z","timestamp":1349051924000},"page":"199-209","source":"Crossref","is-referenced-by-count":115,"title":["Identification of genital tract markers in the human seminal plasma using an integrative genomics approach"],"prefix":"10.1093","volume":"28","author":[{"given":"A.D.","family":"Rolland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Lavigne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Dauly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Calvel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Kervarrec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Freour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Evrard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Rioux-Leclercq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Auger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Pineau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,9,27]]},"reference":[{"key":"key\n\t\t\t\t20170522102936_DES360C1","first-page":"3341","article-title":"Serum inhibin B levels reflect Sertoli cell function in normal men and men with testicular dysfunction","volume":"81","author":"Anawalt","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170522102936_DES360C2","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1093\/humrep\/13.4.920","article-title":"Inhibin B in seminal plasma: testicular origin and relationship to spermatogenesis","volume":"13","author":"Anderson","year":"1998","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170522102936_DES360C3","doi-asserted-by":"crossref","first-page":"e49","DOI":"10.1111\/j.1365-2605.2010.01124.x","article-title":"Second to fourth digit ratios, male genital development and reproductive health: a clinical study among fertile men and testis cancer patients","volume":"34","author":"Auger","year":"2011","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20170522102936_DES360C4","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1021\/pr100745u","article-title":"Proteomic analysis of seminal plasma from normal volunteers and post-vasectomy patients identifies over 2000 proteins and candidate biomarkers of the urogenital system","volume":"10","author":"Batruch","year":"2011","journal-title":"J Proteome Res"},{"key":"key\n\t\t\t\t20170522102936_DES360C5","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1002\/pmic.200800389","article-title":"The art of observing rare protein species in proteomes with peptide ligand libraries","volume":"9","author":"Boschetti","year":"2009","journal-title":"Proteomics"},{"key":"key\n\t\t\t\t20170522102936_DES360C6","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1439-0272.1991.tb02550.x","article-title":"How frequent is unintentional childlessness in Germany?","volume":"23","author":"Bruckert","year":"1991","journal-title":"Andrologia"},{"key":"key\n\t\t\t\t20170522102936_DES360C7","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/S0015-0282(01)02866-7","article-title":"Serum inhibin B may be a reliable marker of the presence of testicular spermatozoa in patients with nonobstructive azoospermia","volume":"76","author":"Brugo-Olmedo","year":"2001","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170522102936_DES360C8","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.fertnstert.2009.01.083","article-title":"Controversies in the management of nonobstructive azoospermia","volume":"91","author":"Carpi","year":"2009","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170522102936_DES360C9","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1021\/pr050153r","article-title":"Exploring the hidden human urinary proteome via ligand library beads","volume":"4","author":"Castagna","year":"2005","journal-title":"J Proteome Res"},{"key":"key\n\t\t\t\t20170522102936_DES360C10","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/1471-2105-9-86","article-title":"The Annotation, Mapping, Expression and Network (AMEN) suite of tools for molecular systems biology","volume":"9","author":"Chalmel","year":"2008","journal-title":"BMC Bioinformatics"},{"key":"key\n\t\t\t\t20170522102936_DES360C11","doi-asserted-by":"crossref","first-page":"8346","DOI":"10.1073\/pnas.0701883104","article-title":"The conserved transcriptome in human and rodent male gametogenesis","volume":"104","author":"Chalmel","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170522102936_DES360C12","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1002\/mrd.20453","article-title":"Identification, molecular cloning, and cellular distribution of the rat homolog of minichromosome maintenance protein 7 (MCM7) in the rat testis","volume":"73","author":"Com","year":"2006","journal-title":"Mol Reprod Dev"},{"key":"key\n\t\t\t\t20170522102936_DES360C13","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1095\/biolreprod.109.079699","article-title":"Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice","volume":"82","author":"Danshina","year":"2010","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170522102936_DES360C14","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1055\/s-2006-958463","article-title":"Semenogelin, the main protein of the human semen coagulum, regulates sperm function","volume":"33","author":"de Lamirande","year":"2007","journal-title":"Semin Thromb Hemost"},{"key":"key\n\t\t\t\t20170522102936_DES360C15","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M110.004127","article-title":"Verification of male infertility biomarkers in seminal plasma by multiplex selected reaction monitoring assay","volume":"10","author":"Drabovich","year":"2011","journal-title":"Mol Cell Proteomics"},{"key":"key\n\t\t\t\t20170522102936_DES360C16","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.jprot.2009.01.007","article-title":"Clinical collection and protein properties of expressed prostatic secretions as a source for biomarkers of prostatic disease","volume":"72","author":"Drake","year":"2009","journal-title":"J Proteomics"},{"key":"key\n\t\t\t\t20170522102936_DES360C17","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1002\/prca.200700228","article-title":"Proteomics of semen and its constituents","volume":"1","author":"Duncan","year":"2007","journal-title":"Proteomics Clin Appl"},{"key":"key\n\t\t\t\t20170522102936_DES360C18","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/j.1939-4640.2002.tb02340.x","article-title":"Possible relationship between seminal plasma inhibin B and spermatogenesis in patients with azoospermia","volume":"23","author":"El Garem","year":"2002","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170522102936_DES360C19","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1093\/humrep\/14.8.2020","article-title":"Anti-Mullerian hormone as a seminal marker for spermatogenesis in non-obstructive azoospermia","volume":"14","author":"Fenichel","year":"1999","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170522102936_DES360C20","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/pros.20089","article-title":"A comprehensive characterization of the peptide and protein constituents of human seminal fluid","volume":"61","author":"Fung","year":"2004","journal-title":"Prostate"},{"key":"key\n\t\t\t\t20170522102936_DES360C21","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/S0015-0282(02)02974-6","article-title":"Successful pregnancy and delivery after testicular sperm extraction despite an undetectable concentration of serum inhibin B in a patient with nonobstructive azoospermia","volume":"77","author":"Guthauser","year":"2002","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170522102936_DES360C22","first-page":"1321","article-title":"Inhibin-B: a likely candidate for the physiologically important form of inhibin in men","volume":"81","author":"Illingworth","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170522102936_DES360C23","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/biostatistics\/4.2.249","article-title":"Exploration, normalization, and summaries of high density oligonucleotide array probe level data","volume":"4","author":"Irizarry","year":"2003","journal-title":"Biostatistics"},{"key":"key\n\t\t\t\t20170522102936_DES360C24","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/aja.2011.61","article-title":"Surgical recovery of sperm in non-obstructive azoospermia","volume":"14","author":"Ishikawa","year":"2012","journal-title":"Asian J Androl"},{"key":"key\n\t\t\t\t20170522102936_DES360C25","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1093\/humrep\/14.5.1250","article-title":"Regional differences in waiting time to pregnancy: pregnancy-based surveys from Denmark, France, Germany, Italy and Sweden. The European infertility and subfecundity study group","volume":"14","author":"Juul","year":"1999","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170522102936_DES360C26","doi-asserted-by":"crossref","DOI":"10.5962\/bhl.title.6940","volume-title":"The Biochemistry of Semen","author":"Mann","year":"1954"},{"key":"key\n\t\t\t\t20170522102936_DES360C27","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1074\/mcp.M900513-MCP200","article-title":"In-depth exploration of cerebrospinal fluid by combining peptide ligand library treatment and label-free protein quantification","volume":"9","author":"Mouton-Barbosa","year":"2010","journal-title":"Mol Cell Proteomics"},{"key":"key\n\t\t\t\t20170522102936_DES360C28","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1095\/biolreprod.108.068353","article-title":"Expression of the gene for mouse lactate dehydrogenase C (Ldhc) is required for male fertility","volume":"79","author":"Odet","year":"2008","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170522102936_DES360C29","doi-asserted-by":"crossref","first-page":"459","DOI":"10.2164\/jandrol.04104","article-title":"A review of the physical and chemical properties of human semen and the formulation of a semen stimulant","volume":"26","author":"Owen","year":"2005","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170522102936_DES360C30","doi-asserted-by":"crossref","first-page":"R40","DOI":"10.1186\/gb-2006-7-5-r40","article-title":"Large-scale and high-confidence proteomic analysis of human seminal plasma","volume":"7","author":"Pilch","year":"2006","journal-title":"Genome Biol"},{"key":"key\n\t\t\t\t20170522102936_DES360C31","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/pros.20860","article-title":"Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen","volume":"69","author":"Poliakov","year":"2009","journal-title":"Prostate"},{"key":"key\n\t\t\t\t20170522102936_DES360C32","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1002\/mas.20178","article-title":"The ProteoMiner and the FortyNiners: searching for gold nuggets in the proteomic arena","volume":"27","author":"Righetti","year":"2008","journal-title":"Mass Spectrom Rev"},{"key":"key\n\t\t\t\t20170522102936_DES360C33","doi-asserted-by":"crossref","first-page":"3980","DOI":"10.1002\/pmic.200500904","article-title":"Protein equalizer technology: the quest for a \u2018democratic proteome\u2019","volume":"6","author":"Righetti","year":"2006","journal-title":"Proteomics"},{"key":"key\n\t\t\t\t20170522102936_DES360C34","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00441-005-1127-3","article-title":"Seminal plasma and male factor signalling in the female reproductive tract","volume":"322","author":"Robertson","year":"2005","journal-title":"Cell Tissue Res"},{"issue":"Suppl. 1","key":"key\n\t\t\t\t20170522102936_DES360C35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1600-0897.2011.01033.x","article-title":"Seminal plasma proteins: what role do they play?","volume":"66","author":"Rodriguez-Martinez","year":"2011","journal-title":"Am J Reprod Immunol"},{"key":"key\n\t\t\t\t20170522102936_DES360C36","volume-title":"WHO Manual for the Standardized Investigation, Diagnosis and Management of the Infertile Male","author":"Rowe","year":"2000"},{"key":"key\n\t\t\t\t20170522102936_DES360C37","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.1021\/pr801017a","article-title":"Directed sample interrogation utilizing an accurate mass exclusion-based data-dependent acquisition strategy (AMEx)","volume":"8","author":"Rudomin","year":"2009","journal-title":"J Proteome Res"},{"key":"key\n\t\t\t\t20170522102936_DES360C38","doi-asserted-by":"crossref","first-page":"4055","DOI":"10.1021\/pr070339l","article-title":"Proteomic analysis of human blood serum using peptide library beads","volume":"6","author":"Sennels","year":"2007","journal-title":"J Proteome Res"},{"key":"key\n\t\t\t\t20170522102936_DES360C39","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1093\/molehr\/gam051","article-title":"Region-specific gene expression profiling along the human epididymis","volume":"13","author":"Thimon","year":"2007","journal-title":"Mol Hum Reprod"},{"key":"key\n\t\t\t\t20170522102936_DES360C40","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1093\/humrep\/den181","article-title":"Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach","volume":"23","author":"Thimon","year":"2008","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170522102936_DES360C41","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/pros.10255","article-title":"Proteomic analysis of human prostasomes","volume":"56","author":"Utleg","year":"2003","journal-title":"Prostate"},{"key":"key\n\t\t\t\t20170522102936_DES360C42","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.ccr.2005.10.001","article-title":"Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression","volume":"8","author":"Varambally","year":"2005","journal-title":"Cancer Cell"},{"key":"key\n\t\t\t\t20170522102936_DES360C43","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1093\/humrep\/17.4.971","article-title":"Serum inhibin B cannot predict testicular sperm retrieval in patients with non-obstructive azoospermia","volume":"17","author":"Vernaeve","year":"2002","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170522102936_DES360C44","first-page":"2496","article-title":"Serum inhibin B in combination with serum follicle-stimulating hormone (FSH) is a more sensitive marker than serum FSH alone for impaired spermatogenesis in men, but cannot predict the presence of sperm in testicular tissue samples","volume":"84","author":"von Eckardstein","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170522102936_DES360C45","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/aja.2009.26","article-title":"Proteomic analysis of seminal plasma from asthenozoospermia patients reveals proteins that affect oxidative stress responses and semen quality","volume":"11","author":"Wang","year":"2009","journal-title":"Asian J Androl"},{"key":"key\n\t\t\t\t20170522102936_DES360C46","doi-asserted-by":"crossref","first-page":"3705","DOI":"10.1093\/bioinformatics\/bth449","article-title":"limmaGUI: a graphical user interface for linear modeling of microarray data","volume":"20","author":"Wettenhall","year":"2004","journal-title":"Bioinformatics"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/28\/1\/199\/17370977\/des360.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T22:40:03Z","timestamp":1714430403000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humrep\/article-lookup\/doi\/10.1093\/humrep\/des360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,27]]},"references-count":46,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,9,27]]},"published-print":{"date-parts":[[2013,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/des360","relation":{},"ISSN":["1460-2350","0268-1161"],"issn-type":[{"value":"1460-2350","type":"electronic"},{"value":"0268-1161","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9,27]]}}}