{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T18:32:41Z","timestamp":1781375561557,"version":"3.54.1"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1093\/humrep\/des441","type":"journal-article","created":{"date-parts":[[2013,1,6]],"date-time":"2013-01-06T01:14:17Z","timestamp":1357434857000},"page":"1006-1012","source":"Crossref","is-referenced-by-count":70,"title":["Reproductive decision-making in young female carriers of a BRCA mutation"],"prefix":"10.1093","volume":"28","author":[{"given":"L.S.","family":"Donnelly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Moynihan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Bancroft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.G.R.","family":"Evans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Eeles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Lavery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Ormondroyd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,1,4]]},"reference":[{"key":"key\n\t\t\t\t20170522104534_DES441C1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1136\/jmg.30.7.549","article-title":"Five year study of prenatal testing for Huntington's disease: demand, attitudes, and psychological assessment","volume":"30","author":"Adam","year":"1993","journal-title":"J Med Genet"},{"key":"key\n\t\t\t\t20170522104534_DES441C2","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1086\/375033","article-title":"Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies","volume":"72","author":"Antoniou","year":"2003","journal-title":"Am J Hum Genet"},{"key":"key\n\t\t\t\t20170522104534_DES441C3","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/BF02895156","article-title":"Psychological distress among women seeking genetics counselling for breast-ovarian cancer risk: the contribution of personality and appraisal","volume":"19","author":"Audrain","year":"1997","journal-title":"Ann Behav Med"},{"key":"key\n\t\t\t\t20170522104534_DES441C4","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1191\/1478088706qp063oa","article-title":"Using thematic analysis in psychology","volume":"3","author":"Braun","year":"2006","journal-title":"Qual Res Psychol"},{"key":"key\n\t\t\t\t20170522104534_DES441C5","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/sj.ejhg.5201774","article-title":"The complexity of reproductive decision-making in asymptomatic carriers of the Huntington mutation","volume":"15","author":"Decruyenaere","year":"2007","journal-title":"Eur J Hum Genet"},{"key":"key\n\t\t\t\t20170522104534_DES441C6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s10897-005-0619-3","article-title":"Negotiating responsibility: case studies of reproductive decision-making and prenatal genetic testing in families facing Huntington disease","volume":"14","author":"Downing","year":"2005","journal-title":"J Genet Couns"},{"key":"key\n\t\t\t\t20170522104534_DES441C37","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1186\/bcr748","article-title":"Are BRCA1- and BRCA2- related breast cancers associated with increased mortality?","volume":"6","author":"Evans","year":"2004","journal-title":"Breast Cancer Res"},{"key":"key\n\t\t\t\t20170522104534_DES441C7","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/1471-2407-8-155","article-title":"Penetrance estimates for BRCA1 and BRCA2 based on genetic testing in a Clinical Cancer Genetics service setting: risks of breast\/ovarian cancer quoted should reflect the cancer burden in the family","volume":"8","author":"Evans","year":"2008","journal-title":"BMC Cancer"},{"key":"key\n\t\t\t\t20170522104534_DES441C8","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1093\/humrep\/den471","article-title":"Opinion about reproductive decision making among individuals undergoing BRCA1\/2 genetic testing in a multicentre Spanish cohort","volume":"24","author":"Fortuny","year":"2009","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170522104534_DES441C9","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1038\/sj.bjc.6600253","article-title":"Predictive testing for BRCA1\/2: attributes, risk perception and management in a multi-centre clinical cohort","volume":"86","author":"Foster","year":"2002","journal-title":"Br J Cancer"},{"key":"key\n\t\t\t\t20170522104534_DES441C10","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1399-0004.2009.01273.x","article-title":"Preimplantation Genetic Diagnosis","volume":"76","author":"Geraedts","year":"2009","journal-title":"Clin Genet"},{"key":"key\n\t\t\t\t20170522104534_DES441C11","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev-psych-120709-145346","article-title":"Heuristic decision-making","volume":"62","author":"Gigerenzer","year":"2011","journal-title":"Ann Rev Psychol"},{"key":"key\n\t\t\t\t20170522104534_DES441C12","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/1467-9566.00175","article-title":"Doing the right thing: genetic risk and responsibility","volume":"21","author":"Hallowell","year":"1999","journal-title":"Sociol Health Ill"},{"key":"key\n\t\t\t\t20170522104534_DES441C13","volume-title":"Rational Choice in an Uncertain World: The Psychology of Judgment and Decision-Making","author":"Hastie","year":"2010"},{"key":"key\n\t\t\t\t20170522104534_DES441C14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.pec.2009.11.017","article-title":"Conceptualizing couples' decision-making in PGD: Emerging cognitive, emotional and moral dimensions","volume":"81","author":"Hershberger","year":"2010","journal-title":"Patient Educ Couns"},{"key":"key\n\t\t\t\t20170522104534_DES441C15","author":"Human Fertilisation and Embyology Act","year":"1990"},{"key":"key\n\t\t\t\t20170522104534_DES441C16","article-title":"Choices and Boundaries\u2014public discussion summary","author":"HFEA","year":"2006"},{"key":"key\n\t\t\t\t20170522104534_DES441C17","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1111\/j.1572-0241.2007.01168.x","article-title":"Attitudes toward prenatal genetic testing in patients with familial adenomatous polyposis","volume":"102","author":"Kastrinos","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"key\n\t\t\t\t20170522104534_DES441C18","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/0029-7844(95)00405-X","article-title":"An inevitable dilemma: prenatal testing for mutations in the BRCA1 breast-ovarian cancer susceptibility gene","volume":"87","author":"Lancaster","year":"1996","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170522104534_DES441C19","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/ajmg.10006","article-title":"Facilitating informed choice in prenatal testing: how well are we doing?","volume":"106","author":"Marteau","year":"2001","journal-title":"Am J Med Genet"},{"key":"key\n\t\t\t\t20170522104534_DES441C20","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1093\/humrep\/dem055","article-title":"Views of BRCA gene mutation carriers on preimplantation genetic diagnosis as a reproductive option for hereditary breast and ovarian cancer","volume":"22","author":"Menon","year":"2007","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170522104534_DES441C21","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1093\/jnci\/94.20.1564","article-title":"Breast cancer risk perception among women who have undergone prophylactic bilateral mastectomy","volume":"94","author":"Metcalfe","year":"2002","journal-title":"J Natl Cancer Inst"},{"key":"key\n\t\t\t\t20170522104534_DES441C22","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1080\/03085140050174750","article-title":"Genetic risk and the birth of the somatic individual","volume":"29","author":"Novas","year":"2000","journal-title":"Econ Soc"},{"key":"key\n\t\t\t\t20170522104534_DES441C23","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.ijnurstu.2007.01.014","article-title":"The use of cognitive continuum theory and patient scenarios to explore nurse prescribers' pharmacological knowledge and decision-making","volume":"45","author":"Offredy","year":"2008","journal-title":"Int J Nurs Stud"},{"key":"key\n\t\t\t\t20170522104534_DES441C24","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/ejhg.2011.146","article-title":"Attitudes to reproductive genetic testing in women who had a positive BRCA test before having children: a qualitative analysis","volume":"20","author":"Ormondroyd","year":"2012","journal-title":"Eur J Hum Genet"},{"key":"key\n\t\t\t\t20170522104534_DES441C25","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1016\/j.fertnstert.2008.03.019","article-title":"Attitudes of high-risk women toward preimplantation genetic diagnosis","volume":"91","author":"Quinn","year":"2009","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170522104534_DES441C26","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1093\/jnci\/djn442","article-title":"Meta-analysis of risk reducing estimates associated with risk-reducing salpingo-oophorectomy in BRCA1 or BRCA2 mutation carriers","volume":"101","author":"Rebbeck","year":"2009","journal-title":"J Natl Cancer Inst"},{"key":"key\n\t\t\t\t20170522104534_DES441C27","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/14636770701701774","article-title":"On doing \u2018being ordinary\u2019: women's accounts of BRCA testing and maternal responsibility","volume":"26","author":"Rowley","year":"2007","journal-title":"New Genet Soc"},{"key":"key\n\t\t\t\t20170522104534_DES441C28","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1177\/0884217505276291","article-title":"The travesty of choosing after positive prenatal diagnosis","volume":"34","author":"Sandelowski","year":"2005","journal-title":"J Obstet Gynecol Neonatal Nurs"},{"key":"key\n\t\t\t\t20170522104534_DES441C29","doi-asserted-by":"crossref","first-page":"3918","DOI":"10.1200\/JCO.2008.17.4227","article-title":"A lesser evil: prophylactic mastectomy for women at high risk for breast cancer","volume":"26","author":"Schover","year":"2008","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t20170522104534_DES441C30","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1158\/1055-9965.733.13.5","article-title":"Fertility intentions following testing for a BRCA1 gene mutation","volume":"13","author":"Smith","year":"2004","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"key\n\t\t\t\t20170522104534_DES441C31","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s10689-007-9171-7","article-title":"Cancer risk reduction and reproductive concerns in female BRCA1\/2 mutation carriers","volume":"7","author":"Staton","year":"2008","journal-title":"Fam Cancer"},{"key":"key\n\t\t\t\t20170522104534_DES441C32","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0277-9536(03)00155-2","article-title":"Predictive genetic testing for Huntington's disease: context, appraisal and moral imperatives","volume":"58","author":"Taylor","year":"2004","journal-title":"Soc Sci Med"},{"key":"key\n\t\t\t\t20170522104534_DES441C33","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1126\/science.185.4157.1124","article-title":"Judgment under uncertainty: heuristics and biases","volume":"185","author":"Tversky","year":"1974","journal-title":"Science"},{"key":"key\n\t\t\t\t20170522104534_DES441C34","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1016\/j.ejca.2004.05.004","article-title":"Psychological distress in women at increased risk of breast cancer: the role of risk perception","volume":"40","author":"vanDooren","year":"2004","journal-title":"Eur J Cancer"},{"key":"key\n\t\t\t\t20170522104534_DES441C35","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1038\/sj.bjc.6602207","article-title":"Foster C, Eeles R, Eccles D, Ashley S, Davidson R, Mackay P, Morrison J, Hopwood P, Evans DGR, Psychosocial study collaborators. Psychosocial impact of breast\/ovarian (BRCA 1\/2) cancer-predictive genetic testing in a UK multi-centre clinical cohort","volume":"91","author":"Watson","year":"2004","journal-title":"Br J Cancer"},{"key":"key\n\t\t\t\t20170522104534_DES441C36","volume-title":"Multiple Criteria Decision-Making","author":"Zeleny","year":"1982"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/28\/4\/1006\/17371215\/des441.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T13:44:42Z","timestamp":1687959882000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humrep\/article-lookup\/doi\/10.1093\/humrep\/des441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,4]]},"references-count":37,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2013,1,4]]},"published-print":{"date-parts":[[2013,4]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/des441","relation":{},"ISSN":["1460-2350","0268-1161"],"issn-type":[{"value":"1460-2350","type":"electronic"},{"value":"0268-1161","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1,4]]}}}