{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:02:27Z","timestamp":1791583347540,"version":"4.3.4"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"10","funder":[{"name":"Department of Clinical Medicine, Aarhus University Hospital"},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum. Reprod."],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1093\/humrep\/dev192","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T01:11:33Z","timestamp":1438909893000},"page":"2419-2426","source":"Crossref","is-referenced-by-count":68,"title":["Only a minority of sex chromosome abnormalities are detected by a national prenatal screening program for Down syndrome"],"prefix":"10.1093","volume":"30","author":[{"given":"Mette Hansen","family":"Viuff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirstine","family":"Stochholm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"Uldbjerg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgitte Bruun","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Danish Fetal Medicine Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus H\u00f8jbjerg","family":"Gravholt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,8,6]]},"reference":[{"key":"2015091716321672000_30.10.2419.1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199704)17:4<363::AID-PD79>3.0.CO;2-O"},{"key":"2015091716321672000_30.10.2419.2","doi-asserted-by":"publisher","DOI":"10.1111\/apa.12008"},{"key":"2015091716321672000_30.10.2419.3","doi-asserted-by":"publisher","DOI":"10.1111\/jsm.12277"},{"key":"2015091716321672000_30.10.2419.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.03.021"},{"key":"2015091716321672000_30.10.2419.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1994.tb18097.x"},{"key":"2015091716321672000_30.10.2419.6","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021491"},{"key":"2015091716321672000_30.10.2419.7","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1374"},{"key":"2015091716321672000_30.10.2419.8","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2010.148"},{"key":"2015091716321672000_30.10.2419.9","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-10-24"},{"key":"2015091716321672000_30.10.2419.10","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a2547"},{"key":"2015091716321672000_30.10.2419.11","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddm246"},{"key":"2015091716321672000_30.10.2419.12","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970040704"},{"key":"2015091716321672000_30.10.2419.13","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2008.265"},{"key":"2015091716321672000_30.10.2419.14","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2012.3931"},{"key":"2015091716321672000_30.10.2419.15","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.312.7022.16"},{"key":"2015091716321672000_30.10.2419.16","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1159\/000226594","article-title":"Population screening for genetic disorders in the 21st century: evidence, economics, and ethics","volume":"13","author":"Grosse","year":"2009","journal-title":"Public Health Genomics"},{"key":"2015091716321672000_30.10.2419.17","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-2382"},{"key":"2015091716321672000_30.10.2419.18","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deq060"},{"key":"2015091716321672000_30.10.2419.19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02151.x"},{"key":"2015091716321672000_30.10.2419.20","first-page":"282","article-title":"Rates of chromosome abnormalities at different maternal ages","volume":"58","author":"Hook","year":"1981","journal-title":"Obstet Gynecol"},{"key":"2015091716321672000_30.10.2419.21","doi-asserted-by":"publisher","DOI":"10.1089\/gtmb.2014.0236"},{"key":"2015091716321672000_30.10.2419.22","doi-asserted-by":"publisher","DOI":"10.1038\/gim.0b013e31822e57a7"},{"key":"2015091716321672000_30.10.2419.23","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1515\/JPM.2005.071","article-title":"The best marker combination using the integrated screening test approach for detecting various chromosomal aneuploidies","volume":"33","author":"Maymon","year":"2005","journal-title":"J Perinat Med"},{"key":"2015091716321672000_30.10.2419.24","doi-asserted-by":"publisher","DOI":"10.1210\/er.2011-1059"},{"key":"2015091716321672000_30.10.2419.25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2009.03715.x"},{"key":"2015091716321672000_30.10.2419.26","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-1049"},{"key":"2015091716321672000_30.10.2419.27","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199806)18:6<581::AID-PD301>3.0.CO;2-6"},{"key":"2015091716321672000_30.10.2419.28","doi-asserted-by":"publisher","DOI":"10.1159\/000264259"},{"key":"2015091716321672000_30.10.2419.29","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.13030167.x"},{"key":"2015091716321672000_30.10.2419.30","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(200005)20:5<411::AID-PD822>3.0.CO;2-2"},{"key":"2015091716321672000_30.10.2419.31","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(200005)20:5<390::AID-PD824>3.0.CO;2-B"},{"key":"2015091716321672000_30.10.2419.32","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0558"},{"key":"2015091716321672000_30.10.2419.33","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-15"},{"key":"2015091716321672000_30.10.2419.34","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-15"},{"key":"2015091716321672000_30.10.2419.35","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/ajmg.a.33214","article-title":"Mortality and incidence in women with 47,XXX and variants","volume":"152A","author":"Stochholm","year":"2010","journal-title":"Am J Med Genet A"},{"key":"2015091716321672000_30.10.2419.36","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-11-1066"},{"key":"2015091716321672000_30.10.2419.37","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1002\/ajmg.a.35539","article-title":"Socio-economic factors affect mortality in 47,XYY syndrome\u2014a comparison with the background population and Klinefelter syndrome","volume":"158A","author":"Stochholm","year":"2012","journal-title":"Am J Med Genet A"},{"key":"2015091716321672000_30.10.2419.38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2013.03.008"},{"key":"2015091716321672000_30.10.2419.39","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-8"},{"key":"2015091716321672000_30.10.2419.40","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004175"},{"key":"2015091716321672000_30.10.2419.41","doi-asserted-by":"publisher","DOI":"10.1159\/000109231"},{"key":"2015091716321672000_30.10.2419.42","doi-asserted-by":"publisher","DOI":"10.1159\/000080099"},{"key":"2015091716321672000_30.10.2419.43","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1515\/JPEM.2007.20.5.607","article-title":"Weight deficit at birth and Turner's syndrome","volume":"20","author":"Wisniewski","year":"2007","journal-title":"J Pediatr Endocrinol Metab"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/30\/10\/2419\/17371863\/dev192.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T17:11:06Z","timestamp":1589562666000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humrep\/article-lookup\/doi\/10.1093\/humrep\/dev192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,6]]},"references-count":43,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2015,9,17]]},"published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1093\/humrep\/dev192"],"URL":"https:\/\/doi.org\/10.1093\/humrep\/dev192","relation":{},"ISSN":["0268-1161","1460-2350"],"issn-type":[{"value":"0268-1161","type":"print"},{"value":"1460-2350","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,6]]}}}