{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T18:38:38Z","timestamp":1787251118432,"version":"build-2736575974"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"11","funder":[{"DOI":"10.13039\/501100000951","name":"Cancer Council Victoria","doi-asserted-by":"publisher","award":["491079"],"award-info":[{"award-number":["491079"]}],"id":[{"id":"10.13039\/501100000951","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"Australian National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1021127"],"award-info":[{"award-number":["1021127"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"Australian National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1085435"],"award-info":[{"award-number":["1085435"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"Australian National Health and Medical Research Council","doi-asserted-by":"publisher","award":["145780"],"award-info":[{"award-number":["145780"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"Australian National Health and Medical Research Council","doi-asserted-by":"publisher","award":["288713"],"award-info":[{"award-number":["288713"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"name":"RD Wright Career Development Award","award":["465121"],"award-info":[{"award-number":["465121"]}]},{"name":"Senior Research Fellowship","award":["1042298"],"award-info":[{"award-number":["1042298"]}]},{"name":"the Victorian Government's Operational Infrastructure Support and an Australian Postgraduate Award"},{"name":"China Council Scholarship (LX)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,1]]},"DOI":"10.1093\/humrep\/dex289","type":"journal-article","created":{"date-parts":[[2017,8,25]],"date-time":"2017-08-25T07:09:09Z","timestamp":1503644949000},"page":"2254-2268","source":"Crossref","is-referenced-by-count":130,"title":["N-cadherin identifies human endometrial epithelial progenitor cells by in vitro stem cell assays"],"prefix":"10.1093","volume":"32","author":[{"given":"Hong P T","family":"Nguyen","sequence":"first","affiliation":[{"name":"The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia"},{"name":"Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria 3168, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Xiao","sequence":"additional","affiliation":[{"name":"The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia"},{"name":"Department of Gynecology and Obstetrics, West China Second University Hospital of Sichuan University, Chengdu, Sichuan 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A","family":"Deane","sequence":"additional","affiliation":[{"name":"The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia"},{"name":"Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria 3168, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ker-Sin","family":"Tan","sequence":"additional","affiliation":[{"name":"The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona L","family":"Cousins","sequence":"additional","affiliation":[{"name":"The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia"},{"name":"Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria 3168, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Masuda","sequence":"additional","affiliation":[{"name":"The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia"},{"name":"Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria 3168, Australia"},{"name":"Current address: Department of Obstetrics and Gynaecology, Keio University, Tokyo 160-8582, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl N","family":"Sprung","sequence":"additional","affiliation":[{"name":"Centre for Innate Immunity and Infectious Disease, Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia"},{"name":"Department of Molecular and Translational Science, Monash University, Clayton, Victoria 3168, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Rosamilia","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria 3168, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3590-2077","authenticated-orcid":false,"given":"Caroline E","family":"Gargett","sequence":"additional","affiliation":[{"name":"The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia"},{"name":"Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria 3168, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,9,27]]},"reference":[{"key":"key\n\t\t\t\t20180328173150_dex289C1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.scr.2015.02.002","article-title":"CDH2 and CDH11 act as regulators of stem cell fate decisions","volume":"14","author":"Alimperti","year":"2015","journal-title":"Stem Cell Res"},{"key":"key\n\t\t\t\t20180328173150_dex289C2","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s00404-013-3040-4","article-title":"Epithelial to mesenchymal transition (EMT) seems to be regulated differently in endometriosis and the endometrium","volume":"289","author":"Bartley","year":"2014","journal-title":"Arch Gynecol Obstet"},{"key":"key\n\t\t\t\t20180328173150_dex289C3","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1242\/dev.148478","article-title":"Development of organoids from mouse and human endometrium showing endometrial epithelium physiology and long-term expandability","volume":"144","author":"Boretto","year":"2017","journal-title":"Development"},{"key":"key\n\t\t\t\t20180328173150_dex289C4","doi-asserted-by":"crossref","first-page":"e21221","DOI":"10.1371\/journal.pone.0021221","article-title":"Reconstruction of endometrium from human endometrial side population cell lines","volume":"6","author":"Cervello","year":"2011","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180328173150_dex289C5","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1095\/biolreprod.103.024109","article-title":"Clonogenicity of human endometrial epithelial and stromal cells","volume":"70","author":"Chan","year":"2004","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20180328173150_dex289C6","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1387\/ijdb.041793ld","article-title":"N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling","volume":"48","author":"Derycke","year":"2004","journal-title":"Int J Dev Biol"},{"key":"key\n\t\t\t\t20180328173150_dex289C7","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0002-9378(97)80022-1","article-title":"Comparison of endometrial growth produced by unopposed conjugated estrogens or by micronized estradiol in postmenopausal women","volume":"176","author":"Ettinger","year":"1997","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20180328173150_dex289C8","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/0002-9378(79)90302-8","article-title":"Proliferation kinetics of human endometrium during the normal menstrual cycle","volume":"133","author":"Ferenczy","year":"1979","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20180328173150_dex289C9","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/humupd\/dml045","article-title":"Uterine stem cells: what is the evidence?","volume":"13","author":"Gargett","year":"2007","journal-title":"Hum Reprod Update"},{"key":"key\n\t\t\t\t20180328173150_dex289C10","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.mce.2008.02.026","article-title":"Hormone and growth factor signaling in endometrial renewal: Role of stem\/progenitor cells","volume":"288","author":"Gargett","year":"2008","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20180328173150_dex289C11","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s11154-012-9221-9","article-title":"Endometrial regeneration and endometrial stem\/progenitor cells","volume":"13","author":"Gargett","year":"2012","journal-title":"Rev Endocr Metab Disord"},{"key":"key\n\t\t\t\t20180328173150_dex289C12","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1095\/biolreprod.108.075226","article-title":"Isolation and culture of epithelial progenitors and mesenchymal stem cells from human endometrium","volume":"80","author":"Gargett","year":"2009","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20180328173150_dex289C13","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1093\/humrep\/dep036","article-title":"A re-appraisal of the morphological changes within the endometrium during menstruation: a hysteroscopic, histological and scanning electron microscopic study","volume":"24","author":"Garry","year":"2009","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180328173150_dex289C14","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1634\/stemcells.2006-0167","article-title":"N-Cadherin is expressed by putative stem\/progenitor cells and melanocytes in the human limbal epithelial stem cell niche","volume":"25","author":"Hayashi","year":"2007","journal-title":"Stem Cells"},{"key":"key\n\t\t\t\t20180328173150_dex289C15","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.scr.2012.11.001","article-title":"Aquaporin 1-positive stromal niche-like cells directly interact with N-cadherin-positive clusters in the basal limbal epithelium","volume":"10","author":"Higa","year":"2013","journal-title":"Stem Cell Res"},{"key":"key\n\t\t\t\t20180328173150_dex289C16","doi-asserted-by":"crossref","first-page":"e44285","DOI":"10.1371\/journal.pone.0044285","article-title":"Stromal-to-epithelial transition during postpartum endometrial regeneration","volume":"7","author":"Huang","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180328173150_dex289C17","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1530\/REP-09-0411","article-title":"A cancer stem cell origin for human endometrial carcinoma?","volume":"140","author":"Hubbard","year":"2010","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20180328173150_dex289C18","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1210\/er.2004-0021","article-title":"Endocrine regulation of menstruation","volume":"27","author":"Jabbour","year":"2006","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20180328173150_dex289C19","doi-asserted-by":"crossref","first-page":"9590","DOI":"10.1523\/JNEUROSCI.3699-13.2014","article-title":"N-cadherin promotes recruitment and migration of neural progenitor cells from the SVZ neural stem cell niche into demyelinated lesions","volume":"34","author":"Klingener","year":"2014","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20180328173150_dex289C20","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1038\/nrg1225","article-title":"Developmental genetics of the female reproductive tract in mammals","volume":"4","author":"Kobayashi","year":"2003","journal-title":"Nat Rev Genet"},{"key":"key\n\t\t\t\t20180328173150_dex289C21","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/humrep\/17.10.2725","article-title":"Endometriosis results from the dislocation of basal endometrium","volume":"17","author":"Leyendecker","year":"2002","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180328173150_dex289C22","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00404-009-1191-0","article-title":"The pathophysiology of endometriosis and adenomyosis: tissue injury and repair","volume":"280","author":"Leyendecker","year":"2009","journal-title":"Arch Gynecol Obstet"},{"key":"key\n\t\t\t\t20180328173150_dex289C23","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1177\/1933719116657196","article-title":"Endometrial expression of homeobox genes and cell adhesion molecules in infertile women with intramural fibroids during window of implantation","volume":"24","author":"Makker","year":"2017","journal-title":"Reprod Sci"},{"key":"key\n\t\t\t\t20180328173150_dex289C24","doi-asserted-by":"crossref","first-page":"e10387","DOI":"10.1371\/journal.pone.0010387","article-title":"Stem cell-like properties of the endometrial side population: implication in endometrial regeneration","volume":"5","author":"Masuda","year":"2010","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180328173150_dex289C25","doi-asserted-by":"crossref","first-page":"e53498","DOI":"10.1371\/journal.pone.0053498","article-title":"Slug controls stem\/progenitor cell growth dynamics during mammary gland morphogenesis","volume":"7","author":"Nassour","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180328173150_dex289C26","doi-asserted-by":"crossref","first-page":"2870","DOI":"10.1210\/en.2011-1839","article-title":"Differential expression of wnt signaling molecules between pre- and postmenopausal endometrial epithelial cells suggests a population of putative epithelial stem\/progenitor cells reside in the basalis layer","volume":"153","author":"Nguyen","year":"2012","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20180328173150_dex289C27","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1093\/oxfordjournals.humrep.a137291","article-title":"Expression of intermediate filament in endometrial glands changes with the onset of pregnancy and in endometriosis","volume":"6","author":"Norwitz","year":"1991","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180328173150_dex289C28","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1095\/biolreprod40.3.681","article-title":"The basalis of the primate endometrium: a bifunctional germinal compartment","volume":"40","author":"Padykula","year":"1989","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20180328173150_dex289C29","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1016\/j.fertnstert.2010.04.055","article-title":"Expression of E- and N-cadherin and CD44 in endometrium and hydrosalpinges from infertile women","volume":"94","author":"Poncelet","year":"2010","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20180328173150_dex289C30","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s12958-015-0084-2","article-title":"Aberrant expression of Notch1\/numb\/snail signaling, an epithelial mesenchymal transition related pathway, in adenomyosis","volume":"13","author":"Qi","year":"2015","journal-title":"Reprod Biol Endocrinol"},{"key":"key\n\t\t\t\t20180328173150_dex289C31","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1126\/science.1128004","article-title":"Lhx2 maintains stem cell character in hair follicles","volume":"312","author":"Rhee","year":"2006","journal-title":"Science"},{"key":"key\n\t\t\t\t20180328173150_dex289C32","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1002\/dneu.22077","article-title":"N-cadherin regulates the proliferation and differentiation of ventral midbrain dopaminergic progenitors","volume":"73","author":"Sakane","year":"2013","journal-title":"Dev Neurobiol"},{"key":"key\n\t\t\t\t20180328173150_dex289C33","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1196\/annals.1434.014","article-title":"Stem cells and the pathogenesis of endometriosis","volume":"1127","author":"Sasson","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"key\n\t\t\t\t20180328173150_dex289C34","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.fertnstert.2005.02.056","article-title":"Putative stem cell activity of human endometrial epithelial and stromal cells during the menstrual cycle","volume":"84","author":"Schwab","year":"2005","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20180328173150_dex289C35","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1093\/humrep\/den051","article-title":"Identification of surface markers for prospective isolation of human endometrial stromal colony-forming cells","volume":"23","author":"Schwab","year":"2008","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180328173150_dex289C36","doi-asserted-by":"crossref","first-page":"655","DOI":"10.2174\/1566524013363168","article-title":"In search of pathogenic mechanisms in endometriosis: the challenge for molecular cell biology","volume":"1","author":"Starzinski-Powitz","year":"2001","journal-title":"Curr Mol Med"},{"key":"key\n\t\t\t\t20180328173150_dex289C37","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1146\/annurev.bi.59.070190.001321","article-title":"Cadherins: a molecular family important in selective cell-cell adhesion","volume":"59","author":"Takeichi","year":"1990","journal-title":"Annu Rev Biochem"},{"key":"key\n\t\t\t\t20180328173150_dex289C38","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1001\/jama.292.1.81","article-title":"Endometrial cells derived from donor stem cells in bone marrow transplant recipients","volume":"292","author":"Taylor","year":"2004","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180328173150_dex289C39","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1038\/ncb3516","article-title":"Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium","volume":"19","author":"Turco","year":"2017","journal-title":"Nat Cell Biol"},{"key":"key\n\t\t\t\t20180328173150_dex289C40","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1093\/humrep\/deu159","article-title":"Mesenchymal stem\/stromal cells in postmenopausal endometrium","volume":"29","author":"Ulrich","year":"2014","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180328173150_dex289C41","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1093\/humrep\/det285","article-title":"SSEA-1 isolates human endometrial basal glandular epithelial cells: phenotypic and functional characterization and implications in the pathogenesis of endometriosis","volume":"28","author":"Valentijn","year":"2013","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180328173150_dex289C42","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/modpathol.2009.127","article-title":"Cadherin expression in gastrointestinal tract endometriosis: possible role in deep tissue invasion and development of malignancy","volume":"23","author":"Van Patten","year":"2010","journal-title":"Mod Pathol"},{"key":"key\n\t\t\t\t20180328173150_dex289C43","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s12943-015-0448-4","article-title":"P-cadherin and the journey to cancer metastasis","volume":"14","author":"Vieira","year":"2015","journal-title":"Mol Cancer"},{"key":"key\n\t\t\t\t20180328173150_dex289C44","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1101\/gad.14.10.1169","article-title":"Cadherin superfamily genes: functions, genomic organization, and neurologic diversity","volume":"14","author":"Yagi","year":"2000","journal-title":"Genes Dev"},{"key":"key\n\t\t\t\t20180328173150_dex289C45","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1038\/nature02041","article-title":"Identification of the haematopoietic stem cell niche and control of the niche size","volume":"425","author":"Zhang","year":"2003","journal-title":"Nature"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/32\/11\/2254\/21345555\/dex289.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T15:51:39Z","timestamp":1659369099000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humrep\/article\/32\/11\/2254\/4259275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,27]]},"references-count":45,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2017,9,27]]},"published-print":{"date-parts":[[2017,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/dex289","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.732030678.793541091","asserted-by":"object"}]},"ISSN":["0268-1161","1460-2350"],"issn-type":[{"value":"0268-1161","type":"print"},{"value":"1460-2350","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,11]]},"published":{"date-parts":[[2017,9,27]]}}}