{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:22:08Z","timestamp":1787008928054,"version":"build-2736575974"},"reference-count":54,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T00:00:00Z","timestamp":1531699200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,1]]},"DOI":"10.1093\/humrep\/dey244","type":"journal-article","created":{"date-parts":[[2018,6,19]],"date-time":"2018-06-19T15:23:20Z","timestamp":1529421800000},"page":"1696-1704","source":"Crossref","is-referenced-by-count":31,"title":["Ovarian response is associated with anogenital distance in patients undergoing controlled ovarian stimulation for IVF"],"prefix":"10.1093","volume":"33","author":[{"given":"F","family":"Fabregues","sequence":"first","affiliation":[{"name":"Institut Cl\u00ednic of Gynecology, Obstetrics and Neonatology, Hospital Cl\u00ednic- Institut d\u00b4Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Faculty of Medicine-University of Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Gonz\u00e1lez-Foruria","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic of Gynecology, Obstetrics and Neonatology, Hospital Cl\u00ednic- Institut d\u00b4Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Faculty of Medicine-University of Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Pe\u00f1arrubia","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic of Gynecology, Obstetrics and Neonatology, Hospital Cl\u00ednic- Institut d\u00b4Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Faculty of Medicine-University of Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Carmona","sequence":"additional","affiliation":[{"name":"Institut Cl\u00ednic of Gynecology, Obstetrics and Neonatology, Hospital Cl\u00ednic- Institut d\u00b4Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Faculty of Medicine-University of Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,7,16]]},"reference":[{"key":"key\n\t\t\t\t20180828120411_dey244C1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1017\/S2040174417001118","article-title":"Anogenital distance in newborn daughters of women with polycystic ovary syndrome indicates fetal testosterone exposure","volume":"9","author":"Barrett","year":"2018","journal-title":"J Dev Orig Health Dis"},{"key":"key\n\t\t\t\t20180828120411_dey244C2","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1017\/S2040174414000646","article-title":"Stability of proposed biomarkers of prenatal androgen exposure over the menstrual cycle","volume":"6","author":"Barrett","year":"2015","journal-title":"J Dev Orig Health Dis"},{"key":"key\n\t\t\t\t20180828120411_dey244C3","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1289\/ehp.1408163","article-title":"Prenatal phthalate exposures and anogenital distance in Swedish boys","volume":"123","author":"Bornehag","year":"2015","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20180828120411_dey244C4","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1210\/er.2009-0006","article-title":"Ovarian aging: mechanisms and clinical consequences","volume":"30","author":"Broekmans","year":"2009","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20180828120411_dey244C5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0378-3782(97)00028-5","article-title":"Is the age of menopause determined in-utero?","volume":"49","author":"Cresswell","year":"1997","journal-title":"Early Hum Dev"},{"key":"key\n\t\t\t\t20180828120411_dey244C6","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1210\/jc.2012-4057","article-title":"Clinical review: anogenital distance or digit length ratio as measures of fetal androgen exposure: relationship to male reproductive development and its disorders","volume":"98","author":"Dean","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20180828120411_dey244C7","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1055\/s-0033-1356478","article-title":"What is normal ovarian reserve?","volume":"31","author":"Dillon","year":"2013","journal-title":"Semin Reprod Med"},{"key":"key\n\t\t\t\t20180828120411_dey244C8","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1111\/j.1439-0531.2012.02003.x","article-title":"Variation in ano-genital distance in spontaneously cycling female mice","volume":"47","author":"Dusek","year":"2012","journal-title":"Reprod Domest Anim"},{"key":"key\n\t\t\t\t20180828120411_dey244C9","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1093\/oxfordjournals.humrep.a137570","article-title":"Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause","volume":"7","author":"Faddy","year":"1992","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C10","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1365-2605.2005.00563.x","article-title":"Disruption of reproductive development in male rat offspring following in utero exposure to phthalate esters","volume":"29","author":"Foster","year":"2006","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20180828120411_dey244C11","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1080\/10408444.2016.1211090","article-title":"Human exposure to environmental contaminants and congenital anomalies: a critical review","volume":"47","author":"Foster","year":"2017","journal-title":"Crit Rev Toxicol"},{"key":"key\n\t\t\t\t20180828120411_dey244C12","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.fertnstert.2008.09.073","article-title":"Recent cigarette smoking and assisted reproductive technologies outcome","volume":"93","author":"Fuentes","year":"2010","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20180828120411_dey244C13","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1095\/biolreprod65.5.1311","article-title":"Developmental biology of uterine glands","volume":"65","author":"Gray","year":"2001","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C14","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1365-2605.2005.00636.x","article-title":"Adverse effects of environmental antiandrogens and androgens on reproductive development in mammals","volume":"29","author":"Gray","year":"2006","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20180828120411_dey244C15","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1258\/002367777780936620","article-title":"Sexing mouse pups","volume":"11","author":"Greenham","year":"1977","journal-title":"Lab Anim"},{"key":"key\n\t\t\t\t20180828120411_dey244C16","first-page":"250","article-title":"Individualization of controlled ovarian stimulation in vitro fertilization using ovarian reserve markers","volume":"69","author":"Grisendi","year":"2017","journal-title":"Minerva Ginecol"},{"key":"key\n\t\t\t\t20180828120411_dey244C17","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1148\/radiology.143.1.7063747","article-title":"The meaning and use of the area under a receiver operating characteristic (ROC) curve","volume":"143","author":"Hanley","year":"1982","journal-title":"Radiology"},{"key":"key\n\t\t\t\t20180828120411_dey244C18","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1055\/s-0033-1356477","article-title":"Predicting reproductive age with biomarkers of ovarian reserve--how (and what) are we measuring?","volume":"31","author":"Hansen","year":"2013","journal-title":"Semin Reprod Med"},{"key":"key\n\t\t\t\t20180828120411_dey244C19","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.fertnstert.2010.04.006","article-title":"Correlation of ovarian reserve tests with histologically determined primordial follicle number","volume":"95","author":"Hansen","year":"2011","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20180828120411_dey244C20","doi-asserted-by":"crossref","first-page":"17525","DOI":"10.1073\/pnas.1207854109","article-title":"Bisphenol A alters early oogenesis and follicle formation in the fetal ovary of the rhesus monkey","volume":"109","author":"Hunt","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20180828120411_dey244C21","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1203\/00006450-200005000-00003","article-title":"Reduced uterine and ovarian size in adolescent girls born small for gestational age","volume":"47","author":"Ibanez","year":"2000","journal-title":"Pediatr Res"},{"key":"key\n\t\t\t\t20180828120411_dey244C22","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1210\/jcem.87.5.8459","article-title":"Hypersecretion of FSH in infant boys and girls born small for gestational age","volume":"87","author":"Ibanez","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20180828120411_dey244C23","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1093\/humrep\/det286","article-title":"Shorter anogenital distance correlates with undescended testis: a detailed genital anthropometric analysis in human newborns","volume":"28","author":"Jain","year":"2013","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C24","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1093\/humrep\/14.7.1744","article-title":"A rational approach to the management of low responders in in-vitro fertilization","volume":"14","author":"Karande","year":"1999","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C25","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/S0022-5347(05)67107-8","article-title":"Urethral development in the fetal rabbit and induction of hypospadias: a model for human development","volume":"164","author":"Kurzrock","year":"2000","journal-title":"J Urol"},{"key":"key\n\t\t\t\t20180828120411_dey244C26","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1093\/humupd\/dmt037","article-title":"Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers: from theory to practice","volume":"20","author":"La Marca","year":"2014","journal-title":"Hum Reprod Update"},{"key":"key\n\t\t\t\t20180828120411_dey244C27","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s10815-013-0144-5","article-title":"Ovarian sensitivity index is a better measure of ovarian responsiveness to gonadotrophin stimulation than the number of oocytes during in-vitro fertilization treatment","volume":"31","author":"Li","year":"2014","journal-title":"J Assist Reprod Genet"},{"key":"key\n\t\t\t\t20180828120411_dey244C28","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1095\/biolreprod.111.091173","article-title":"Xenobiotic effects on ovarian preantral follicles","volume":"85","author":"Mark-Kappeler","year":"2011","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C29","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/1476-069X-11-90","article-title":"Anogenital distance is related to ovarian follicular number in young Spanish women: a cross-sectional study","volume":"11","author":"Mendiola","year":"2012","journal-title":"Environ Health"},{"key":"key\n\t\t\t\t20180828120411_dey244C30","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1093\/humrep\/dew163","article-title":"Endometriomas and deep infiltrating endometriosis in adulthood are strongly associated with anogenital distance, a biomarker for prenatal hormonal environment","volume":"31","author":"Mendiola","year":"2016","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C31","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1111\/1471-0528.12627","article-title":"Longer anogenital distance is associated with higher testosterone levels in women: a cross-sectional study","volume":"121","author":"Mira-Escolano","year":"2014","journal-title":"BJOG"},{"key":"key\n\t\t\t\t20180828120411_dey244C32","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.rbmo.2013.09.026","article-title":"Anogenital distance of women in relation to their mother\u2019s gynaecological characteristics before or during pregnancy","volume":"28","author":"Mira-Escolano","year":"2014","journal-title":"Reprod Biomed Online"},{"key":"key\n\t\t\t\t20180828120411_dey244C33","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1210\/en.2014-1534","article-title":"Anogenital distance plasticity in adulthood: implications for its use as a biomarker of fetal androgen action","volume":"156","author":"Mitchell","year":"2015","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20180828120411_dey244C34","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.reprotox.2012.02.006","article-title":"Reproductive effects in F1 adult females exposed in utero to moderate to high doses of mono-2-ethylhexylphthalate (MEHP)","volume":"34","author":"Moyer","year":"2012","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20180828120411_dey244C35","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1093\/humrep\/deh674","article-title":"Previous cycle cancellation due to poor follicular development as a predictor of ovarian response in cycles stimulated with gonadotrophin-releasing hormone agonist-gonadotrophin treatment","volume":"20","author":"Penarrubia","year":"2005","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C36","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1093\/humrep\/deh718","article-title":"Basal and stimulation day 5 anti-Mullerian hormone serum concentrations as predictors of ovarian response and pregnancy in assisted reproductive technology cycles stimulated with gonadotropin-releasing hormone agonist--gonadotropin treatment","volume":"20","author":"Penarrubia","year":"2005","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C37","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/humupd\/dmt057","article-title":"Environmental and developmental origins of ovarian reserve","volume":"20","author":"Richardson","year":"2014","journal-title":"Hum Reprod Update"},{"key":"key\n\t\t\t\t20180828120411_dey244C38","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1093\/humrep\/dex274","article-title":"Presence of polycystic ovary syndrome is associated with longer anogenital distance in adult Mediterranean women","volume":"32","author":"Sanchez-Ferrer","year":"2017","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C39","doi-asserted-by":"crossref","first-page":"76.e71","DOI":"10.1016\/j.jpurol.2014.11.018","article-title":"Anogenital distance and penile width measurements in The Infant Development and the Environment Study (TIDES): methods and predictors","volume":"11","author":"Sathyanarayana","year":"2015","journal-title":"J Pediatr Urol"},{"key":"key\n\t\t\t\t20180828120411_dey244C40","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1095\/biolreprod.108.072801","article-title":"Developmental programming: differential effects of prenatal testosterone and dihydrotestosterone on follicular recruitment, depletion of follicular reserve, and ovarian morphology in sheep","volume":"80","author":"Smith","year":"2009","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C41","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.reprotox.2013.09.008","article-title":"The association of bisphenol-A urinary concentrations with antral follicle counts and other measures of ovarian reserve in women undergoing infertility treatments","volume":"42","author":"Souter","year":"2013","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20180828120411_dey244C42","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.envres.2008.08.007","article-title":"Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans","volume":"108","author":"Swan","year":"2008","journal-title":"Environ Res"},{"key":"key\n\t\t\t\t20180828120411_dey244C43","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1289\/ehp.8100","article-title":"Decrease in anogenital distance among male infants with prenatal phthalate exposure","volume":"113","author":"Swan","year":"2005","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20180828120411_dey244C44","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1093\/humrep\/deu363","article-title":"First trimester phthalate exposure and anogenital distance in newborns","volume":"30","author":"Swan","year":"2015","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C45","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/humupd\/dmg007","article-title":"Clinical management of low ovarian response to stimulation for IVF: a systematic review","volume":"9","author":"Tarlatzis","year":"2003","journal-title":"Hum Reprod Update"},{"key":"key\n\t\t\t\t20180828120411_dey244C46","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/humupd\/8.2.141","article-title":"The variability of female reproductive ageing","volume":"8","author":"te Velde","year":"2002","journal-title":"Hum Reprod Update"},{"key":"key\n\t\t\t\t20180828120411_dey244C47","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1289\/ehp.0900881","article-title":"Anogenital distance from birth to 2 years: a population study","volume":"117","author":"Thankamony","year":"2009","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20180828120411_dey244C48","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/andr.12156","article-title":"Anogenital distance as a marker of androgen exposure in humans","volume":"4","author":"Thankamony","year":"2016","journal-title":"Andrology"},{"key":"key\n\t\t\t\t20180828120411_dey244C49","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.reprotox.2017.07.009","article-title":"Fertility and anogenital distance in women","volume":"73","author":"Wainstock","year":"2017","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20180828120411_dey244C50","doi-asserted-by":"crossref","first-page":"e8772","DOI":"10.1371\/journal.pone.0008772","article-title":"Human ovarian reserve from conception to the menopause","volume":"5","author":"Wallace","year":"2010","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180828120411_dey244C51","first-page":"937","article-title":"Polycystic ovary syndrome is associated with anogenital distance, a marker of prenatal androgen exposure","volume":"32","author":"Wu","year":"2017","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C52","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1093\/humrep\/12.8.1736","article-title":"Effects of cigarette smoking and age on the maturation of human oocytes","volume":"12","author":"Zenzes","year":"1997","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20180828120411_dey244C53","doi-asserted-by":"crossref","first-page":"5651","DOI":"10.1007\/s11033-011-1372-3","article-title":"Fetal exposure to bisphenol A affects the primordial follicle formation by inhibiting the meiotic progression of oocytes","volume":"39","author":"Zhang","year":"2012","journal-title":"Mol Biol Rep"},{"key":"key\n\t\t\t\t20180828120411_dey244C54","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/clinchem\/39.4.561","article-title":"Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine","volume":"39","author":"Zweig","year":"1993","journal-title":"Clin Chem"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/33\/9\/1696\/25591685\/dey244.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T18:42:26Z","timestamp":1604428946000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humrep\/article\/33\/9\/1696\/5054591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,16]]},"references-count":54,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2018,7,16]]},"published-print":{"date-parts":[[2018,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/dey244","relation":{},"ISSN":["0268-1161","1460-2350"],"issn-type":[{"value":"0268-1161","type":"print"},{"value":"1460-2350","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,9]]},"published":{"date-parts":[[2018,7,16]]}}}