{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:42:47Z","timestamp":1790671367308,"version":"4.1.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T00:00:00Z","timestamp":1544054400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,2,1]]},"DOI":"10.1093\/humrep\/dey352","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T12:12:11Z","timestamp":1542197531000},"page":"261-267","source":"Crossref","is-referenced-by-count":11,"title":["Cost-effectiveness analysis of medical management versus conservative surgery for early tubal pregnancy"],"prefix":"10.1093","volume":"34","author":[{"given":"G","family":"Bourel","sequence":"first","affiliation":[{"name":"INSERM, Universit\u00e9 Paris-Saclay, Univ. Paris-Sud, UVSQ, Centre de Recherche en Epid\u00e9miologie et Sant\u00e9 des Populations, H\u00f4pital Paul Brousse, 16 av Paul Vaillant Couturier, Villejuif, France"},{"name":"Unit\u00e9 de recherche m\u00e9dico-\u00e9conomique, CHU de Montpellier, 191 Av. du Doyen Gaston Giraud, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Pelletier-Fleury","sequence":"additional","affiliation":[{"name":"INSERM, Universit\u00e9 Paris-Saclay, Univ. Paris-Sud, UVSQ, Centre de Recherche en Epid\u00e9miologie et Sant\u00e9 des Populations, H\u00f4pital Paul Brousse, 16 av Paul Vaillant Couturier, Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Bouyer","sequence":"additional","affiliation":[{"name":"INSERM, Universit\u00e9 Paris-Saclay, Univ. Paris-Sud, UVSQ, Centre de Recherche en Epid\u00e9miologie et Sant\u00e9 des Populations, H\u00f4pital Paul Brousse, 16 av Paul Vaillant Couturier, Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Delbarre","sequence":"additional","affiliation":[{"name":"INSERM, Universit\u00e9 Paris-Saclay, Univ. Paris-Sud, UVSQ, Centre de Recherche en Epid\u00e9miologie et Sant\u00e9 des Populations, H\u00f4pital Paul Brousse, 16 av Paul Vaillant Couturier, Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Fernandez","sequence":"additional","affiliation":[{"name":"INSERM, Universit\u00e9 Paris-Saclay, Univ. Paris-Sud, UVSQ, Centre de Recherche en Epid\u00e9miologie et Sant\u00e9 des Populations, H\u00f4pital Paul Brousse, 16 av Paul Vaillant Couturier, Villejuif, France"},{"name":"GHU Sud, AP-HP, Service de Gyn\u00e9cologie Obst\u00e9trique, H\u00f4pital Bic\u00eatre, 78 Rue du G\u00e9n\u00e9ral Leclerc, Le Kremlin Bic\u00eatre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Capmas","sequence":"additional","affiliation":[{"name":"INSERM, Universit\u00e9 Paris-Saclay, Univ. Paris-Sud, UVSQ, Centre de Recherche en Epid\u00e9miologie et Sant\u00e9 des Populations, H\u00f4pital Paul Brousse, 16 av Paul Vaillant Couturier, Villejuif, France"},{"name":"GHU Sud, AP-HP, Service de Gyn\u00e9cologie Obst\u00e9trique, H\u00f4pital Bic\u00eatre, 78 Rue du G\u00e9n\u00e9ral Leclerc, Le Kremlin Bic\u00eatre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,12,6]]},"reference":[{"key":"key\n\t\t\t\t2019012510361352400_dey352C1","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1111\/j.1447-0756.2008.00746.x","article-title":"Prophylactic intratubal injection of methotrexate after linear salpingostomy for prevention of persistent ectopic pregnancy","volume":"34","author":"Akira","year":"2008","journal-title":"J Obstet Gynaecol Res"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C2","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1056\/NEJMcp0810384","article-title":"Clinical practice. Ectopic pregnancy","volume":"361","author":"Barnhart","year":"2009","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C3","first-page":"S8","article-title":"Epidemiology of ectopic pregnancy: incidence, risk factors and outcomes","volume":"32","author":"Bouyer","year":"2003","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C4","doi-asserted-by":"crossref","first-page":"3224","DOI":"10.1093\/humrep\/17.12.3224","article-title":"Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases","volume":"17","author":"Bouyer","year":"2002","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C5","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/(SICI)1099-1050(199707)6:4<327::AID-HEC282>3.0.CO;2-W","article-title":"Pulling cost-effectiveness analysis up by its bootstraps: a non-parametric approach to confidence interval estimation","volume":"6","author":"Briggs","year":"1997","journal-title":"Health Econ"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C6","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.fertnstert.2014.01.029","article-title":"Treatment of ectopic pregnancies in 2014: new answers to some old questions","volume":"101","author":"Capmas","year":"2014","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C7","author":"Drummond","year":"2015"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C8","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1093\/humrep\/det037","article-title":"Fertility after ectopic pregnancy: the DEMETER randomized trial","volume":"28","author":"Fernandez","year":"2013","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C9","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S0029-7844(96)00370-5","article-title":"Methotrexate prophylaxis for persistent ectopic pregnancy after conservative treatment by salpingostomy","volume":"89","author":"Graczykowski","year":"1997","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C10","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1093\/aje\/kwp425","article-title":"Multiple imputation for missing data: fully conditional specification versus multivariate normal imputation","volume":"171","author":"Lee","year":"2010","journal-title":"Am J Epidemiol"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C11","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/S0002-9378(99)70330-3","article-title":"Treatment of tubal pregnancy in the netherlands: an economic comparison of systemic methotrexate administration and laparoscopic salpingostomy","volume":"181","author":"Mol","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C12","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1093\/humrep\/dev162","article-title":"Cost-effectiveness of salpingotomy and salpingectomy in women with tubal pregnancy (a randomized controlled trial)","volume":"30","author":"Mol","year":"2015","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C13","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0015-0282(98)00212-X","article-title":"Systemic methotrexate therapy versus laparoscopic salpingostomy in patients with tubal pregnancy. Part I. Impact on patients\u2019 health-related quality of life","volume":"70","author":"Nieuwkerk","year":"1998","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C14","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/S0015-0282(98)00213-1","article-title":"Systemic methotrexate therapy versus laparoscopic salpingostomy in tubal pregnancy. Part II. Patient preferences for systemic methotrexate","volume":"70","author":"Nieuwkerk","year":"1998","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C15","first-page":"989","article-title":"Resolution of hormonal markers of ectopic gestation: a randomized trial comparing single-dose intramuscular methotrexate with salpingostomy","volume":"92","author":"Saraj","year":"1998","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C16","first-page":"204","article-title":"An economic evaluation of single dose systemic methotrexate and laparoscopic surgery for the treatment of unruptured ectopic pregnancy","volume":"108","author":"Sowter","year":"2001","journal-title":"BJOG"},{"key":"key\n\t\t\t\t2019012510361352400_dey352C17","first-page":"447","article-title":"Cost-effectiveness analysis of laparoscopic surgery versus methotrexate: comparison of data recorded in an ectopic pregnancy registry","volume":"32","author":"Vaissade","year":"2003","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"}],"container-title":["Human Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humrep\/article-pdf\/34\/2\/261\/27583474\/dey352.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,2]],"date-time":"2019-11-02T05:01:30Z","timestamp":1572670890000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humrep\/article\/34\/2\/261\/5231901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,6]]},"references-count":17,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,12,6]]},"published-print":{"date-parts":[[2019,2,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humrep\/dey352","relation":{},"ISSN":["0268-1161","1460-2350"],"issn-type":[{"value":"0268-1161","type":"print"},{"value":"1460-2350","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,2]]},"published":{"date-parts":[[2018,12,6]]}}}