{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:58:13Z","timestamp":1791223093275,"version":"4.1.0"},"reference-count":299,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T00:00:00Z","timestamp":1684195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,5]]},"abstract":"Abstract<\/jats:title>\n \n BACKGROUND<\/jats:title>\n A normal chromosomal constitution defined through PGT-A assessing all chromosomes on trophectoderm (TE) biopsies represents the strongest predictor of embryo implantation. Yet, its positive predictive value is not higher than 50\u201360%. This gap of knowledge on the causes of euploid blastocysts\u2019 reproductive failure is known as \u2018the black box of implantation\u2019.<\/jats:p>\n <\/jats:sec>\n \n OBJECTIVE AND RATIONALE<\/jats:title>\n Several embryonic, maternal, paternal, clinical, and IVF laboratory features were scrutinized for their putative association with reproductive success or implantation failure of euploid blastocysts.<\/jats:p>\n <\/jats:sec>\n \n SEARCH METHODS<\/jats:title>\n A systematic bibliographical search was conducted without temporal limits up to August 2021. The keywords were \u2018(blastocyst OR day5 embryo OR day6 embryo OR day7 embryo) AND (euploid OR chromosomally normal OR preimplantation genetic testing) AND (implantation OR implantation failure OR miscarriage OR abortion OR live birth OR biochemical pregnancy OR recurrent implantation failure)\u2019. Overall, 1608 items were identified and screened. We included all prospective or retrospective clinical studies and randomized-controlled-trials (RCTs) that assessed any feature associated with live-birth rates (LBR) and\/or miscarriage rates (MR) among non-mosaic euploid blastocyst transfer after TE biopsy and PGT-A. In total, 41 reviews and 372 papers were selected, clustered according to a common focus, and thoroughly reviewed. The PRISMA guideline was followed, the PICO model was adopted, and ROBINS-I and ROB 2.0 scoring were used to assess putative bias. Bias across studies regarding the LBR was also assessed using visual inspection of funnel plots and the trim and fill method. Categorical data were combined with a pooled-OR. The random-effect model was used to conduct the meta-analysis. Between-study heterogeneity was addressed using I2. Whenever not suitable for the meta-analysis, the included studies were simply described for their results. The study protocol was registered at http:\/\/www.crd.york.ac.uk\/PROSPERO\/ (registration number CRD42021275329).<\/jats:p>\n <\/jats:sec>\n \n OUTCOMES<\/jats:title>\n We included 372 original papers (335 retrospective studies, 30 prospective studies and 7 RCTs) and 41 reviews. However, most of the studies were retrospective, or characterized by small sample sizes, thus prone to bias, which reduces the quality of the evidence to low or very low. Reduced inner cell mass (7 studies, OR: 0.37, 95% CI: 0.27\u20130.52, I2\u2009=\u200953%), or TE quality (9 studies, OR: 0.53, 95% CI: 0.43\u20130.67, I2\u2009=\u200970%), overall blastocyst quality worse than Gardner\u2019s BB-grade (8 studies, OR: 0.40, 95% CI: 0.24\u20130.67, I2\u2009=\u200983%), developmental delay (18 studies, OR: 0.56, 95% CI: 0.49\u20130.63, I2\u2009=\u200947%), and (by qualitative analysis) some morphodynamic abnormalities pinpointed through time-lapse microscopy (abnormal cleavage patterns, spontaneous blastocyst collapse, longer time of morula formation I, time of blastulation (tB), and duration of blastulation) were all associated with poorer reproductive outcomes. Slightly lower LBR, even in the context of PGT-A, was reported among women \u226538\u2009years (7 studies, OR: 0.87, 95% CI: 0.75\u20131.00, I2\u2009=\u200931%), while obesity was associated with both lower LBR (2 studies, OR: 0.66, 95% CI: 0.55\u20130.79, I2\u2009=\u20090%) and higher MR (2 studies, OR: 1.8, 95% CI: 1.08\u20132.99, I2\u2009=\u200952%). The experience of previous repeated implantation failures (RIF) was also associated with lower LBR (3 studies, OR: 0.72, 95% CI: 0.55\u20130.93, I2\u2009=\u20090%). By qualitative analysis, among hormonal assessments, only abnormal progesterone levels prior to transfer were associated with LBR and MR after PGT-A. Among the clinical protocols used, vitrified-warmed embryo transfer was more effective than fresh transfer (2 studies, OR: 1.56, 95% CI: 1.05\u20132.33, I2\u2009=\u200923%) after PGT-A. Lastly, multiple vitrification-warming cycles (2 studies, OR: 0.41, 95% CI: 0.22\u20130.77, I2\u2009=\u200950%) or (by qualitative analysis) a high number of cells biopsied may slightly reduce the LBR, while simultaneous zona-pellucida opening and TE biopsy allowed better results than the Day 3 hatching-based protocol (3 studies, OR: 1.41, 95% CI: 1.18\u20131.69, I2\u2009=\u20090%).<\/jats:p>\n <\/jats:sec>\n \n WIDER IMPLICATIONS<\/jats:title>\n Embryo selection aims at shortening the time-to-pregnancy, while minimizing the reproductive risks. Knowing which features are associated with the reproductive competence of euploid blastocysts is therefore critical to define, implement, and validate safer and more efficient clinical workflows. Future research should be directed towards: (i) systematic investigations of the mechanisms involved in reproductive aging beyond de novo chromosomal abnormalities, and how lifestyle and nutrition may accelerate or exacerbate their consequences; (ii) improved evaluation of the uterine and blastocyst-endometrial dialogue, both of which represent black boxes themselves; (iii) standardization\/automation of embryo assessment and IVF protocols; (iv) additional invasive or preferably non-invasive tools for embryo selection. Only by filling these gaps we may finally crack the riddle behind \u2018the black box of implantation\u2019.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/humupd\/dmad010","type":"journal-article","created":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T21:14:44Z","timestamp":1684271684000},"page":"570-633","source":"Crossref","is-referenced-by-count":145,"title":["Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis"],"prefix":"10.1093","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5390-9221","authenticated-orcid":false,"given":"Danilo","family":"Cimadomo","sequence":"first","affiliation":[{"name":"IVIRMA Global Research Alliance, GENERA, Clinica Valle Giulia , Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Rienzi","sequence":"additional","affiliation":[{"name":"IVIRMA Global Research Alliance, GENERA, Clinica Valle Giulia , Rome, Italy"},{"name":"Department of Biomolecular Sciences, University of Urbino \u201cCarlo Bo\u201d , Urbino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5676-0055","authenticated-orcid":false,"given":"Alessandro","family":"Conforti","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Reproductive Science and Odontostomatology, Federico II University , Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Forman","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Columbia University Irving Medical Centre , New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Canosa","sequence":"additional","affiliation":[{"name":"IVIRMA Global Research Alliance, LIVET , Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Innocenti","sequence":"additional","affiliation":[{"name":"IVIRMA Global Research Alliance, GENERA, Clinica Valle Giulia , Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Poli","sequence":"additional","affiliation":[{"name":"Centrum voor Kinderwens, Dijklander Hospital , Purmerend, The Netherlands"},{"name":"Juno Genetics , Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna","family":"Hynes","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Columbia University Irving Medical Centre , New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Gemmell","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Columbia University Irving Medical Centre , New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0873-3925","authenticated-orcid":false,"given":"Alberto","family":"Vaiarelli","sequence":"additional","affiliation":[{"name":"IVIRMA Global Research Alliance, GENERA, Clinica Valle Giulia , Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Alviggi","sequence":"additional","affiliation":[{"name":"Department of Public Health, Federico II University , Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo Maria","family":"Ubaldi","sequence":"additional","affiliation":[{"name":"IVIRMA Global Research Alliance, GENERA, Clinica Valle Giulia , Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0109-323X","authenticated-orcid":false,"given":"Antonio","family":"Capalbo","sequence":"additional","affiliation":[{"name":"Juno Genetics , Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,5,16]]},"reference":[{"key":"2023090508443947800_dmad010-B1","doi-asserted-by":"crossref","first-page":"621221","DOI":"10.3389\/fendo.2021.621221","article-title":"The morphology of inner cell mass is the strongest predictor of live birth after a frozen-thawed single embryo transfer","volume":"12","author":"Ai","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2023090508443947800_dmad010-B2","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.fertnstert.2010.04.003","article-title":"The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender","volume":"95","author":"Alfarawati","year":"2011","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B3","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.rbmo.2011.02.001","article-title":"Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting","volume":"22","author":"Alpha SiRM and ESHRE SIGE","year":"2011","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B4","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1093\/humrep\/der037","article-title":"The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting","volume":"26","author":"Alpha SiRM and ESHRE SIGoE","year":"2011","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B5","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.rbmo.2020.11.019","article-title":"Multiple cryopreservation-warming cycles, coupled with blastocyst biopsy, negatively affect IVF outcomes","volume":"42","author":"Aluko","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B6","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1093\/humrep\/deab031","article-title":"Individualised luteal phase support in artificially prepared frozen embryo transfer cycles based on serum progesterone levels: a prospective cohort study","volume":"36","author":"\u00c1lvarez","year":"2021","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B7","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.rbmo.2019.07.029","article-title":"Effect of embryo transfer difficulty on live birth rates studied in vitrified-warmed euploid blastocyst transfers","volume":"39","author":"Alvarez","year":"2019","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B8","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1016\/j.fertnstert.2016.02.005","article-title":"A new more detailed stratification of low responders to ovarian stimulation: from a poor ovarian response to a low prognosis concept","volume":"105","author":"Alviggi","year":"2016","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B9","doi-asserted-by":"crossref","first-page":"hoaa008","DOI":"10.1093\/hropen\/hoaa008","article-title":"Eshre Working Group on time-lapse technology: good practice recommendations for the use of time-lapse technology","volume":"2020","author":"Apter","year":"2020","journal-title":"Hum Reprod Open"},{"key":"2023090508443947800_dmad010-B10","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1007\/s10815-019-01482-1","article-title":"Comparison of daily vaginal progesterone gel plus weekly intramuscular progesterone with daily intramuscular progesterone for luteal phase support in single, autologous euploid frozen-thawed embryo transfers","volume":"36","author":"Asoglu","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B11","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1093\/humupd\/dmr039","article-title":"Ovarian antral folliculogenesis during the human menstrual cycle: a review","volume":"18","author":"Baerwald","year":"2012","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B12","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.fertnstert.2016.04.041","article-title":"Impact of multinucleated blastomeres on embryo developmental competence, morphokinetics, and aneuploidy","volume":"106","author":"Balakier","year":"2016","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B13","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1093\/humupd\/dmac022","article-title":"Morphological and morphokinetic associations with aneuploidy: a systematic review and meta-analysis","volume":"28","author":"Bamford","year":"2022","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B14","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1093\/humrep\/dex299","article-title":"High gonadotropin dosage does not affect euploidy and pregnancy rates in IVF PGS cycles with single embryo transfer","volume":"32","author":"Barash","year":"2017","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B15","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1007\/s10815-017-0944-0","article-title":"Association between growth dynamics, morphological parameters, the chromosomal status of the blastocysts, and clinical outcomes in IVF PGS cycles with single embryo transfer","volume":"34","author":"Barash","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B16","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.ejogrb.2021.05.047","article-title":"Correlation between plasmatic progesterone, endometrial receptivity genetic assay and implantation rates in frozen-thawed transferred euploid embryos. A multivariate analysis","volume":"263","author":"Barrenetxea","year":"2021","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2023090508443947800_dmad010-B17","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.rbmo.2019.04.003","article-title":"The window is wide: flexible timing for vitrified-warmed embryo transfer in natural cycles","volume":"39","author":"Bartels","year":"2019","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B18","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s10815-022-02441-z","article-title":"Oocyte aging: looking beyond chromosome segregation errors","volume":"39","author":"Bebbere","year":"2022","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B19","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.fertnstert.2021.03.031","article-title":"The use of propensity score matching to assess the benefit of the endometrial receptivity analysis in frozen embryo transfers","volume":"116","author":"Bergin","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B20","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1007\/s10815-019-01564-0","article-title":"Effect of the vaginal microbiome on the pregnancy rate in women receiving assisted reproductive treatment","volume":"36","author":"Bernabeu","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B21","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.fertnstert.2018.10.001","article-title":"What are patients doing with their mosaic embryos? Decision making after genetic counseling","volume":"111","author":"Besser","year":"2019","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B22","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.fertnstert.2020.07.050","article-title":"Endometriosis does not impact live-birth rates in frozen embryo transfers of euploid blastocysts","volume":"115","author":"Bishop","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B23","doi-asserted-by":"crossref","first-page":"156","DOI":"10.3109\/14647273.2015.1072646","article-title":"How should we choose the \u2018best\u2019 embryo? A commentary on behalf of the British Fertility Society and the Association of Clinical Embryologists","volume":"18","author":"Bolton","year":"2015","journal-title":"Hum Fertil (Camb)"},{"key":"2023090508443947800_dmad010-B24","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.fertnstert.2022.04.020","article-title":"Relationship between paternal factors and embryonic aneuploidy of paternal origin","volume":"118","author":"Bonus","year":"2022","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B25","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/j.rbmo.2021.03.004","article-title":"Which factors affect the likelihood of miscarriage after single euploid blastocyst transfer?","volume":"42","author":"Boynukalin","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B26","doi-asserted-by":"crossref","first-page":"e0227619","DOI":"10.1371\/journal.pone.0227619","article-title":"Parameters impacting the live birth rate per transfer after frozen single euploid blastocyst transfer","volume":"15","author":"Boynukalin","year":"2020","journal-title":"PLoS One"},{"key":"2023090508443947800_dmad010-B27","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/s12958-019-0549-9","article-title":"Measuring the serum progesterone level on the day of transfer can be an additional tool to maximize ongoing pregnancies in single euploid frozen blastocyst transfers","volume":"17","author":"Boynukalin","year":"2019","journal-title":"Reprod Biol Endocrinol"},{"key":"2023090508443947800_dmad010-B28","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.fertnstert.2017.09.013","article-title":"Impact of multiple blastocyst biopsy and vitrification-warming procedures on pregnancy outcomes","volume":"108","author":"Bradley","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B29","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.rbmo.2017.03.013","article-title":"Clinical use of monopronucleated zygotes following blastocyst culture and preimplantation genetic screening, including verification of biparental chromosome inheritance","volume":"34","author":"Bradley","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B30","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.semcdb.2022.01.007","article-title":"Maternal selection of human embryos in early gestation: insights from recurrent miscarriage","volume":"131","author":"Brosens","year":"2022","journal-title":"Semin Cell Dev Biol"},{"key":"2023090508443947800_dmad010-B31","doi-asserted-by":"crossref","first-page":"3894","DOI":"10.1038\/srep03894","article-title":"Uterine selection of human embryos at implantation","volume":"4","author":"Brosens","year":"2014","journal-title":"Sci Rep"},{"key":"2023090508443947800_dmad010-B32","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1016\/j.ajhg.2022.07.009","article-title":"On the reproductive capabilities of aneuploid human preimplantation embryos","volume":"109","author":"Capalbo","year":"2022","journal-title":"Am J Hum Genet"},{"key":"2023090508443947800_dmad010-B33","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1016\/j.ajhg.2021.11.002","article-title":"Mosaic human preimplantation embryos and their developmental potential in a prospective, non-selection clinical trial","volume":"108","author":"Capalbo","year":"2021","journal-title":"Am J Hum Genet"},{"key":"2023090508443947800_dmad010-B34","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1093\/humrep\/deu033","article-title":"Correlation between standard blastocyst morphology, euploidy and implantation: an observational study in two centres involving 956 screened blastocysts","volume":"29","author":"Capalbo","year":"2014","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B35","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.fertnstert.2017.08.004","article-title":"Abnormally fertilized oocytes can result in healthy live births: improved genetic technologies for preimplantation genetic testing can be used to rescue viable embryos in in vitro fertilization cycles","volume":"108","author":"Capalbo","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B36","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1093\/humrep\/dev294","article-title":"Consistent and reproducible outcomes of blastocyst biopsy and aneuploidy screening across different biopsy practitioners: a multicentre study involving 2586 embryo biopsies","volume":"31","author":"Capalbo","year":"2016","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B37","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.fertnstert.2015.09.014","article-title":"MicroRNAs in spent blastocyst culture medium are derived from trophectoderm cells and can be explored for human embryo reproductive competence assessment","volume":"105","author":"Capalbo","year":"2016","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B38","first-page":"492","article-title":"Detecting mosaicism in trophectoderm biopsies: current challenges and future possibilities","volume":"32","author":"Capalbo","year":"2017","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B39","doi-asserted-by":"crossref","first-page":"e0185747","DOI":"10.1371\/journal.pone.0185747","article-title":"Optimal timing of blastocyst vitrification after trophectoderm biopsy for preimplantation genetic screening","volume":"12","author":"Chen","year":"2017","journal-title":"PLoS One"},{"key":"2023090508443947800_dmad010-B40","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1017\/S0967199421000435","article-title":"The effects of the day of trophectoderm biopsy and blastocyst grade on the clinical and neonatal outcomes of preimplantation genetic testing-frozen embryo transfer cycles","volume":"30","author":"Chen","year":"2022","journal-title":"Zygote"},{"key":"2023090508443947800_dmad010-B41","doi-asserted-by":"crossref","first-page":"e0140779","DOI":"10.1371\/journal.pone.0140779","article-title":"Can comprehensive chromosome screening technology improve IVF\/ICSI outcomes? A meta-analysis","volume":"10","author":"Chen","year":"2015","journal-title":"PLoS One"},{"key":"2023090508443947800_dmad010-B42","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1093\/humrep\/deab014","article-title":"Leave the past behind: women\u2019s reproductive history shows no association with blastocysts\u2019 euploidy and limited association with live birth rates after euploid embryo transfers","volume":"36","author":"Cimadomo","year":"2021","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B43","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1093\/humrep\/dey291","article-title":"Associations of blastocyst features, trophectoderm biopsy and other laboratory practice with post-warming behavior and implantation","volume":"33","author":"Cimadomo","year":"2018","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B44","doi-asserted-by":"crossref","first-page":"7193075","DOI":"10.1155\/2016\/7193075","article-title":"The impact of biopsy on human embryo developmental potential during preimplantation genetic diagnosis","volume":"2016","author":"Cimadomo","year":"2016","journal-title":"Biomed Res Int"},{"key":"2023090508443947800_dmad010-B45","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1093\/humrep\/deac175","article-title":"Human blastocyst spontaneous collapse is associated with worse morphological quality and higher degeneration and aneuploidy rates: a comprehensive analysis standardized through artificial intelligence","volume":"37","author":"Cimadomo","year":"2022","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B46","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1093\/humrep\/dez119","article-title":"Definition and validation of a custom protocol to detect miRNAs in the spent media after blastocyst culture: searching for biomarkers of implantation","volume":"34","author":"Cimadomo","year":"2019","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B47","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1093\/humrep\/dey282","article-title":"Inconclusive chromosomal assessment after blastocyst biopsy: prevalence, causative factors and outcomes after re-biopsy and re-vitrification. A multicentre experience","volume":"33","author":"Cimadomo","year":"2018","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B48","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1007\/s10815-018-1195-4","article-title":"Continuous embryo culture elicits higher blastulation but similar cumulative delivery rates than sequential: a large prospective study","volume":"35","author":"Cimadomo","year":"2018","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B49","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.rbmo.2021.09.022","article-title":"Inter-centre reliability in embryo grading across several IVF clinics is limited: implications for embryo selection","volume":"44","author":"Cimadomo","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B50","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1093\/humrep\/deac080","article-title":"How slow is too slow? A comprehensive portrait of Day 7 blastocysts and their clinical value standardized through artificial intelligence","volume":"37","author":"Cimadomo","year":"2022","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B51","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1093\/humrep\/dez078","article-title":"Looking past the appearance: a comprehensive description of the clinical contribution of poor-quality blastocysts to increase live birth rates during cycles with aneuploidy testing","volume":"34","author":"Cimadomo","year":"2019","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B52","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1093\/humrep\/dey217","article-title":"Luteal phase anovulatory follicles result in the production of competent oocytes: intra-patient paired case\u2013control study comparing follicular versus luteal phase stimulations in the same ovarian cycle","volume":"33","author":"Cimadomo","year":"2018","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B53","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s10815-021-02124-1","article-title":"Oocyte competence is independent of the ovulation trigger adopted: a large observational study in a setting that entails vitrified-warmed single euploid blastocyst transfer","volume":"38","author":"Cimadomo","year":"2021","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B54","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.1093\/humrep\/deu278","article-title":"Proposed guidelines on the nomenclature and annotation of dynamic human embryo monitoring by a time-lapse user group","volume":"29","author":"Ciray","year":"2014","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B55","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1093\/humrep\/dez290","article-title":"The human factor: does the operator performing the embryo transfer significantly impact the cycle outcome?","volume":"35","author":"Cirillo","year":"2020","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B56","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.rbmo.2022.06.002","article-title":"Different actors for the same play: the impact of the embryologist performing the embryo transfer","volume":"45","author":"Cirillo","year":"2022","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B57","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.fertnstert.2016.12.022","article-title":"Optimal euploid embryo transfer strategy, fresh versus frozen, after preimplantation genetic screening with next generation sequencing: a randomized controlled trial","volume":"107","author":"Coates","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B58","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.rbmo.2011.12.012","article-title":"Accumulation of oocytes: a new strategy for managing low-responder patients","volume":"24","author":"Cobo","year":"2012","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B59","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1093\/humupd\/dmz015","article-title":"Potential genetic causes of miscarriage in euploid pregnancies: a systematic review","volume":"25","author":"Colley","year":"2019","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B60","doi-asserted-by":"crossref","first-page":"R69","DOI":"10.1152\/ajpregu.00239.2012","article-title":"Corpus luteal contribution to maternal pregnancy physiology and outcomes in assisted reproductive technologies","volume":"304","author":"Conrad","year":"2013","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"2023090508443947800_dmad010-B61","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1093\/humupd\/dmab016","article-title":"Plasticity of the human preimplantation embryo: developmental dogmas, variations on themes and self-correction","volume":"27","author":"Coticchio","year":"2021","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B62","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1093\/humrep\/deab011","article-title":"Perturbations of morphogenesis at the compaction stage affect blastocyst implantation and live birth rates","volume":"36","author":"Coticchio","year":"2021","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B63","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1093\/humupd\/dmz008","article-title":"The enigmatic morula: mechanisms of development, cell fate determination, self-correction and implications for ART","volume":"25","author":"Coticchio","year":"2019","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B64","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1007\/s10815-020-01948-7","article-title":"Evaluation of the endometrial receptivity assay and the preimplantation genetic test for aneuploidy in overcoming recurrent implantation failure","volume":"37","author":"Cozzolino","year":"2020","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B65","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.fertnstert.2022.07.007","article-title":"Use of the endometrial receptivity array to guide personalized embryo transfer after a failed transfer attempt was associated with a lower cumulative and per transfer live birth rate during donor and autologous cycles","volume":"118","author":"Cozzolino","year":"2022","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B66","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.fertnstert.2020.09.139","article-title":"Female obesity increases the risk of miscarriage of euploid embryos","volume":"115","author":"Cozzolino","year":"2020","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B67","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1093\/humupd\/dmy044","article-title":"Conventional and modern markers of endometrial receptivity: a systematic review and meta-analysis","volume":"25","author":"Craciunas","year":"2019","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B68","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S1701-2163(15)30261-9","article-title":"Technical update: preimplantation genetic diagnosis and screening","volume":"37","author":"Dahdouh","year":"2015","journal-title":"J Obstet Gynaecol Can"},{"key":"2023090508443947800_dmad010-B69","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/j.fertnstert.2015.08.038","article-title":"Comprehensive chromosome screening improves embryo selection: a meta-analysis","volume":"104","author":"Dahdouh","year":"2015","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B70","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1101\/gr.239830.118","article-title":"Single-cell sequencing of primate preimplantation embryos reveals chromosome elimination via cellular fragmentation and blastomere exclusion","volume":"29","author":"Daughtry","year":"2019","journal-title":"Genome Res"},{"key":"2023090508443947800_dmad010-B71","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.fertnstert.2003.11.064","article-title":"Moving to blastocyst biopsy for preimplantation genetic diagnosis and single embryo transfer at Sydney IVF","volume":"82","author":"de Boer","year":"2004","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B72","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1093\/humrep\/deaa002","article-title":"Intracytoplasmic sperm injection is not superior to conventional IVF in couples with non-male factor infertility and preimplantation genetic testing for aneuploidies (PGT-A)","volume":"35","author":"De Munck","year":"2020","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B73","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.fertnstert.2008.10.072","article-title":"Preimplantation genetic screening for aneuploidy of embryos after in vitro fertilization in women aged at least 35 years: a prospective randomized trial","volume":"93","author":"Debrock","year":"2010","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B74","doi-asserted-by":"crossref","first-page":"3422","DOI":"10.1038\/s41598-017-03711-y","article-title":"Performance of four modern whole genome amplification methods for copy number variant detection in single cells","volume":"7","author":"Deleye","year":"2017","journal-title":"Sci Rep"},{"key":"2023090508443947800_dmad010-B75","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1007\/s10815-020-01765-y","article-title":"Preimplantation genetic testing for aneuploidy in poor ovarian responders with four or fewer oocytes retrieved","volume":"37","author":"Deng","year":"2020","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B76","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s10815-019-01621-8","article-title":"The impact of culture conditions on blastocyst formation and aneuploidy rates: a comparison between single-step and sequential media in a large academic practice","volume":"37","author":"Deng","year":"2020","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B77","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.fertnstert.2018.04.004","article-title":"Inheritance of epigenetic dysregulation from male factor infertility has a direct impact on reproductive potential","volume":"110","author":"Denomme","year":"2018","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B78","first-page":"2302","article-title":"Genome-wide haplotyping embryos developing from 0PN and 1PN zygotes increases transferrable embryos in PGT-M","volume":"33","author":"Destouni","year":"2018","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B79","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.fertnstert.2015.05.022","article-title":"Mitochondrial DNA content as a viability score in human euploid embryos: less is better","volume":"104","author":"Diez-Juan","year":"2015","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B80","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.cmet.2015.11.004","article-title":"Obesity and bariatric surgery drive epigenetic variation of spermatozoa in humans","volume":"23","author":"Donkin","year":"2016","journal-title":"Cell Metab"},{"key":"2023090508443947800_dmad010-B81","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.0006-341X.2000.00455.x","article-title":"Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"Duval","year":"2000","journal-title":"Biometrics"},{"key":"2023090508443947800_dmad010-B82","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF01129615","article-title":"Factors influencing the success of in vitro fertilization for alleviating human infertility","volume":"1","author":"Edwards","year":"1984","journal-title":"J In Vitro Fert Embryo Transf"},{"key":"2023090508443947800_dmad010-B83","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s10815-020-02050-8","article-title":"Does blastocyst mitochondrial DNA content affect miscarriage rate in patients undergoing single euploid frozen embryo transfer?","volume":"38","author":"El-Damen","year":"2021","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B84","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.rbmo.2017.06.015","article-title":"The Vienna consensus: report of an expert meeting on the development of ART laboratory performance indicators","volume":"35","author":"ESHRE SIGoE and Alpha SiRM","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B85","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.rbmo.2020.10.017","article-title":"Blastulation rates of sibling oocytes in two IVF culture media: an evidence-based workflow to implement newly commercialized products","volume":"42","author":"Fabozzi","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B86","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.3390\/nu14091918","article-title":"Personalized nutrition in the management of female infertility: new insights on chronic low-grade inflammation","volume":"14","author":"Fabozzi","year":"2022","journal-title":"Nutrients"},{"key":"2023090508443947800_dmad010-B87","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1007\/s10815-017-0966-7","article-title":"Pre-implantation genetic diagnosis-should we use ICSI for all?","volume":"34","author":"Feldman","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B88","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1093\/humrep\/deaa181","article-title":"Metabolic activity of human blastocysts correlates with their morphokinetics, morphological grade, KIDScore and artificial intelligence ranking","volume":"35","author":"Ferrick","year":"2020","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B89","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.fertnstert.2012.04.028","article-title":"Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic sperm injection: a novel, paired randomized controlled trial using DNA fingerprinting","volume":"98","author":"Forman","year":"2012","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B90","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/molehr\/gat073","article-title":"Morphological and cytogenetic assessment of cleavage and blastocyst stage embryos","volume":"20","author":"Fragouli","year":"2014","journal-title":"Mol Hum Reprod"},{"key":"2023090508443947800_dmad010-B91","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.fertnstert.2009.04.053","article-title":"Comprehensive chromosome screening of polar bodies and blastocysts from couples experiencing repeated implantation failure","volume":"94","author":"Fragouli","year":"2010","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B92","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1093\/humrep\/dex292","article-title":"Clinical implications of mitochondrial DNA quantification on pregnancy outcomes: a blinded prospective non-selection study","volume":"32","author":"Fragouli","year":"2017","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B93","doi-asserted-by":"crossref","first-page":"e1005241","DOI":"10.1371\/journal.pgen.1005241","article-title":"Altered levels of mitochondrial DNA are associated with female age, aneuploidy, and provide an independent measure of embryonic implantation potential","volume":"11","author":"Fragouli","year":"2015","journal-title":"PLoS Genet"},{"key":"2023090508443947800_dmad010-B94","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1055\/s-0035-1567821","article-title":"Mitochondrial DNA assessment to determine oocyte and embryo viability","volume":"33","author":"Fragouli","year":"2015","journal-title":"Semin Reprod Med"},{"key":"2023090508443947800_dmad010-B95","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.ajog.2014.09.029","article-title":"Vitamin D levels do not affect IVF outcomes following the transfer of euploid blastocysts","volume":"212","author":"Franasiak","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B96","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.ajog.2014.11.023","article-title":"Reply: to PMID 25265402","volume":"212","author":"Franasiak","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B97","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1097\/GCO.0000000000000357","article-title":"Endometrial microbiome","volume":"29","author":"Franasiak","year":"2017","journal-title":"Curr Opin Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B98","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s10815-015-0614-z","article-title":"Endometrial microbiome at the time of embryo transfer: next-generation sequencing of the 16S ribosomal subunit","volume":"33","author":"Franasiak","year":"2016","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B99","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1080\/09513590.2018.1534952","article-title":"Low serum progesterone the day prior to frozen embryo transfer of euploid embryos is associated with significant reduction in live birth rates","volume":"35","author":"Gaggiotti-Marre","year":"2019","journal-title":"Gynecol Endocrinol"},{"key":"2023090508443947800_dmad010-B100","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0015-0282(00)00518-5","article-title":"Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer","volume":"73","author":"Gardner","year":"2000","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B101","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1093\/humupd\/dmu064","article-title":"Diagnosis of human preimplantation embryo viability","volume":"21","author":"Gardner","year":"2015","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B102","first-page":"377","volume-title":"Toward Reproductive Certainty: Fertility and Genetics Beyond","author":"Gardner","year":"1999"},{"key":"2023090508443947800_dmad010-B103","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/00001703-199906000-00013","article-title":"Culture and transfer of human blastocysts","volume":"11","author":"Gardner","year":"1999","journal-title":"Curr Opin Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B104","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1093\/humrep\/der143","article-title":"Glucose consumption of single post-compaction human embryos is predictive of embryo sex and live birth outcome","volume":"26","author":"Gardner","year":"2011","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B105","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.fertnstert.2012.12.004","article-title":"Analysis of metabolism to select viable human embryos for transfer","volume":"99","author":"Gardner","year":"2013","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B106","doi-asserted-by":"crossref","first-page":"e0179002","DOI":"10.1371\/journal.pone.0179002","article-title":"Sperm DNA fragmentation index does not correlate with blastocyst aneuploidy or morphological grading","volume":"12","author":"Gat","year":"2017","journal-title":"PLoS One"},{"key":"2023090508443947800_dmad010-B107","first-page":"55","article-title":"The Kidscore(TM) D5 algorithm as an additional tool to morphological assessment and PGT-A in embryo selection: a time-lapse study","volume":"24","author":"Gazzo","year":"2020","journal-title":"JBRA Assist Reprod"},{"key":"2023090508443947800_dmad010-B108","first-page":"77","article-title":"Blastocyst contractions are strongly related with aneuploidy, lower implantation rates, and slow-cleaving embryos: a time lapse study","volume":"24","author":"Gazzo","year":"2020","journal-title":"JBRA Assist Reprod"},{"key":"2023090508443947800_dmad010-B109","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1093\/humrep\/deab123","article-title":"Global transcriptomic changes occur in uterine fluid-derived extracellular vesicles during the endometrial window for embryo implantation","volume":"36","author":"Giacomini","year":"2021","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B110","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1016\/j.fertnstert.2021.04.001","article-title":"Weighing in: the impact of obesity on euploid miscarriage rates","volume":"115","author":"Ginsburg","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B111","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1007\/s10815-021-02252-8","article-title":"Individual culture leads to decreased blastocyst formation but does not affect pregnancy outcomes in the setting of a single, vitrified-warmed euploid blastocyst transfer","volume":"38","author":"Glatthorn","year":"2021","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B112","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.fertnstert.2014.11.025","article-title":"Long-term cryopreservation of human oocytes does not increase embryonic aneuploidy","volume":"103","author":"Goldman","year":"2015","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B113","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.tig.2019.08.005","article-title":"De novo mutations reflect development and aging of the human germline","volume":"35","author":"Goldmann","year":"2019","journal-title":"Trends Genet"},{"key":"2023090508443947800_dmad010-B114","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.fertnstert.2015.05.024","article-title":"Morphokinetics as a predictor of self-correction to diploidy in tripronucleated intracytoplasmic sperm injection-derived human embryos","volume":"104","author":"Grau","year":"2015","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B115","doi-asserted-by":"crossref","first-page":"457913","DOI":"10.1155\/2014\/457913","article-title":"Comparative genomic hybridization selection of blastocysts for repeated implantation failure treatment: a pilot study","volume":"2014","author":"Greco","year":"2014","journal-title":"Biomed Res Int"},{"key":"2023090508443947800_dmad010-B116","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s10815-016-0736-y","article-title":"The endometrial preparation for frozen-thawed euploid blastocyst transfer: a prospective randomized trial comparing clinical results from natural modified cycle and exogenous hormone stimulation with GnRH agonist","volume":"33","author":"Greco","year":"2016","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B117","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.fertnstert.2017.11.002","article-title":"Cumulus cell transcriptome profiling is not predictive of live birth after in vitro fertilization: a paired analysis of euploid sibling blastocysts","volume":"109","author":"Green","year":"2018","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B118","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s10815-019-01632-5","article-title":"Sperm DNA fragmentation on the day of fertilization is not associated with embryologic or clinical outcomes after IVF\/ICSI","volume":"37","author":"Green","year":"2020","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B119","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1007\/s10815-015-0549-4","article-title":"Investigating the optimal preconception TSH range for patients undergoing IVF when controlling for embryo quality","volume":"32","author":"Green","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B120","first-page":"255","article-title":"What is the optimal means of preparing the endometrium in frozen-thawed embryo transfer cycles? A systematic review and meta-analysis","volume":"23","author":"Groenewoud","year":"2017","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B121","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.rbmo.2021.09.012","article-title":"A microenvironment of high lactate and low pH created by the blastocyst promotes endometrial receptivity and implantation","volume":"44","author":"Gurner","year":"2022","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B122","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s10815-018-1331-1","article-title":"The number of biopsied trophectoderm cells may affect pregnancy outcomes","volume":"36","author":"Guzman","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B123","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1093\/humrep\/dey091","article-title":"Should extended blastocyst culture include Day 7?","volume":"33","author":"Hammond","year":"2018","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B124","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/humrep\/dey349","article-title":"Tracking quality: can embryology key performance indicators be used to identify clinically relevant shifts in pregnancy rate?","volume":"34","author":"Hammond","year":"2019","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B125","first-page":"99","article-title":"Impact of paternal age on embryology and pregnancy outcomes in the setting of a euploid single-embryo transfer with ejaculated sperm: retrospective cohort study","volume":"1","author":"Hanson","year":"2020","journal-title":"F S Rep"},{"key":"2023090508443947800_dmad010-B126","doi-asserted-by":"crossref","first-page":"i72","DOI":"10.1093\/humrep\/des230","article-title":"The blastocyst","volume":"27(Suppl 1)","author":"Hardarson","year":"2012","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B127","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1530\/jrf.0.0980549","article-title":"Binucleate blastomeres in preimplantation human embryos in vitro: failure of cytokinesis during early cleavage","volume":"98","author":"Hardy","year":"1993","journal-title":"J Reprod Fertil"},{"key":"2023090508443947800_dmad010-B128","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/j.fertnstert.2013.07.2002","article-title":"Diminished effect of maternal age on implantation after preimplantation genetic diagnosis with array comparative genomic hybridization","volume":"100","author":"Harton","year":"2013","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B129","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1016\/j.jrhm.2016.11.006","article-title":"Gene profiling the window of implantation: microarray analyses from human and rodent models","volume":"2","author":"Herington","year":"2016","journal-title":"J Reprod Health Med"},{"key":"2023090508443947800_dmad010-B130","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.fertnstert.2017.08.040","article-title":"Embryo aneuploidy is not impacted by selective serotonin reuptake inhibitor exposure","volume":"108","author":"Hernandez-Nieto","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B131","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1093\/humrep\/deaa123","article-title":"Late follicular phase progesterone elevation during ovarian stimulation is not associated with decreased implantation of chromosomally screened embryos in thaw cycles","volume":"35","author":"Hernandez-Nieto","year":"2020","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B132","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1093\/humrep\/dez129","article-title":"What is the reproductive potential of day 7 euploid embryos?","volume":"34","author":"Hernandez-Nieto","year":"2019","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B133","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1080\/09513590.2019.1684465","article-title":"Infertile patients with inflammatory bowel disease have comparable in vitro fertilization clinical outcomes to the general infertile population","volume":"36","author":"Hernandez-Nieto","year":"2020","journal-title":"Gynecol Endocrinol"},{"key":"2023090508443947800_dmad010-B134","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1093\/humupd\/dmz042","article-title":"Identifying biomarkers for predicting successful embryo implantation: applying single to multi-OMICs to improve reproductive outcomes","volume":"26","author":"Hernandez-Vargas","year":"2020","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B135","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1001\/jama.2022.1892","article-title":"Trends and outcomes for preimplantation genetic testing in the United States, 2014\u20132018","volume":"327","author":"Hipp","year":"2022","journal-title":"JAMA"},{"key":"2023090508443947800_dmad010-B136","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.fertnstert.2019.05.039","article-title":"Embryonic aneuploidy rates are equivalent in natural cycles and gonadotropin-stimulated cycles","volume":"112","author":"Hong","year":"2019","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B137","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.fertnstert.2014.06.009","article-title":"Examining the temperature of embryo culture in in vitro fertilization: a randomized controlled trial comparing traditional core temperature (37 degrees C) to a more physiologic, cooler temperature (36 degrees C)","volume":"102","author":"Hong","year":"2014","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B138","doi-asserted-by":"crossref","first-page":"P1075","DOI":"10.1016\/j.rbmo.2021.02.015","article-title":"Deep learning neural network analysis of human blastocyst expansion from time-lapse image files","volume":"42","author":"Huang","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B139","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.tjog.2018.10.016","article-title":"Early blastulation of day 4 embryo correlates with the increased euploid rate of preimplantation genetic screening cycles","volume":"57","author":"Hung","year":"2018","journal-title":"Taiwan J Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B140","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1093\/humrep\/deaa028","article-title":"No effect of ovarian stimulation and oocyte yield on euploidy and live birth rates: an analysis of 12 298 trophectoderm biopsies","volume":"35","author":"Irani","year":"2020","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B141","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jri.2018.03.002","article-title":"High serum IGF-1 levels are associated with pregnancy loss following frozen-thawed euploid embryo transfer cycles","volume":"127","author":"Irani","year":"2018","journal-title":"J Reprod Immunol"},{"key":"2023090508443947800_dmad010-B142","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.fertnstert.2018.03.032","article-title":"Blastocyst development rate influences implantation and live birth rates of similarly graded euploid blastocysts","volume":"110","author":"Irani","year":"2018","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B143","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.fertnstert.2016.11.012","article-title":"Morphologic grading of euploid blastocysts influences implantation and ongoing pregnancy rates","volume":"107","author":"Irani","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B144","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.ajog.2018.11.1103","article-title":"Does maternal age at retrieval influence the implantation potential of euploid blastocysts?","volume":"220","author":"Irani","year":"2019","journal-title":"Am J Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B145","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.fertnstert.2020.10.051","article-title":"Diminished ovarian reserve is associated with reduced euploid rates via preimplantation genetic testing for aneuploidy independently from age: evidence for concomitant reduction in oocyte quality with quantity","volume":"115","author":"Jaswa","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B146","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1007\/s43032-020-00381-6","article-title":"Effect of embryo developmental stage, morphological grading, and ploidy status on live birth rate in frozen cycles of single blastocyst transfer","volume":"28","author":"Ji","year":"2021","journal-title":"Reprod Sci"},{"key":"2023090508443947800_dmad010-B147","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0015-0282(16)54416-1","article-title":"Relaxin levels in ovum donation pregnancies","volume":"56","author":"Johnson","year":"1991","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B148","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.fertnstert.2019.09.043","article-title":"Embryo\u2019s Natural Motion (enMotion): a paired randomized controlled trial evaluating a dynamic embryo culture system","volume":"113","author":"Juneau","year":"2020","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B149","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1093\/humrep\/det433","article-title":"The role of the osteopontin-integrin alphavbeta3 interaction at implantation: functional analysis using three different in vitro models","volume":"29","author":"Kang","year":"2014","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B150","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/AOG.0b013e318278eeda","article-title":"Association of abnormal ovarian reserve parameters with a higher incidence of aneuploid blastocysts","volume":"121","author":"Katz-Jaffe","year":"2013","journal-title":"Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B151","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41746-019-0096-y","article-title":"Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization","volume":"2","author":"Khosravi","year":"2019","journal-title":"NPJ Digit Med"},{"key":"2023090508443947800_dmad010-B152","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.fertnstert.2020.12.037","article-title":"The Appraisal of Body Content (ABC) trial: increased male or female adiposity does not significantly impact in vitro fertilization laboratory or clinical outcomes","volume":"116","author":"Kim","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B153","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.fertnstert.2021.10.011","article-title":"The concordance rates of an initial trophectoderm biopsy with the rest of the embryo using PGTseq, a targeted next-generation sequencing platform for preimplantation genetic testing-aneuploidy","volume":"117","author":"Kim","year":"2022","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B154","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.3346\/jkms.2019.34.e27","article-title":"Correlation between morphologic grading and euploidy rates of blastocysts, and clinical outcomes in in vitro fertilization preimplantation genetic screening","volume":"34","author":"Kim","year":"2019","journal-title":"J Korean Med Sci"},{"key":"2023090508443947800_dmad010-B155","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.ajog.2018.09.030","article-title":"National mosaic embryo transfer practices: a survey","volume":"219","author":"Kim","year":"2018","journal-title":"Am J Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B156","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1007\/s10815-019-01501-1","article-title":"Assessing the impact of delayed blastulation using time lapse morphokinetics and preimplantation genetic testing in an IVF patient population","volume":"36","author":"Kimelman","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B157","first-page":"6","article-title":"Sperm as obesity propagator?","volume":"17","author":"Koch","year":"2016","journal-title":"Nat Rev Genet"},{"key":"2023090508443947800_dmad010-B158","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/s10815-015-0546-7","article-title":"Serum progesterone levels greater than 20 ng\/dl on day of embryo transfer are associated with lower live birth and higher pregnancy loss rates","volume":"32","author":"Kofinas","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B159","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s10815-016-0671-y","article-title":"Erratum to: serum progesterone levels greater than 20 ng\/ml on day of embryo transfer are associated with lower live birth and higher pregnancy loss rates","volume":"33","author":"Kofinas","year":"2016","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B160","doi-asserted-by":"crossref","first-page":"hoaa020","DOI":"10.1093\/hropen\/hoaa020","article-title":"ESHRE PGT Consortium and SIG Embryology good practice recommendations for polar body and embryo biopsy for PGT","volume":"2020","author":"Kokkali","year":"2020","journal-title":"Hum Reprod Open"},{"key":"2023090508443947800_dmad010-B161","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s10815-017-1060-x","article-title":"Are blastocyst aneuploidy rates different between fertile and infertile populations?","volume":"35","author":"Kort","year":"2018","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B162","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/humrep\/deaa322","article-title":"Impact of low serum progesterone levels on the day of embryo transfer on pregnancy outcome: a prospective cohort study in artificial cycles with vaginal progesterone","volume":"36","author":"Labarta","year":"2021","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B163","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.rbmo.2019.11.011","article-title":"Alternative patterns of partial embryo compaction: prevalence, morphokinetic history and possible implications","volume":"40","author":"Lagalla","year":"2020","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B164","doi-asserted-by":"crossref","first-page":"E936","DOI":"10.1152\/ajpendo.00255.2010","article-title":"Decidual PTEN expression is required for trophoblast invasion in the mouse","volume":"299","author":"Lague","year":"2010","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"2023090508443947800_dmad010-B165","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1071\/RD04102","article-title":"Understanding cellular disruptions during early embryo development that perturb viability and fetal development","volume":"17","author":"Lane","year":"2005","journal-title":"Reprod Fertil Dev"},{"key":"2023090508443947800_dmad010-B166","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/humupd\/dmz033","article-title":"Non-invasive preimplantation genetic testing (niPGT): the next revolution in reproductive genetics?","volume":"26","author":"Leaver","year":"2020","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B167","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.tjog.2019.01.013","article-title":"Performance of preimplantation genetic testing for aneuploidy in IVF cycles for patients with advanced maternal age, repeat implantation failure, and idiopathic recurrent miscarriage","volume":"58","author":"Lee","year":"2019","journal-title":"Taiwan J Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B168","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s10815-014-0417-7","article-title":"In vitro fertilization with preimplantation genetic screening improves implantation and live birth in women age 40 through 43","volume":"32","author":"Lee","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B169","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1007\/s10815-019-01542-6","article-title":"Adjusted mitochondrial DNA quantification in human embryos may not be applicable as a biomarker of implantation potential","volume":"36","author":"Lee","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B170","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1002\/bies.10137","article-title":"Quiet please, do not disturb: a hypothesis of embryo metabolism and viability","volume":"24","author":"Leese","year":"2002","journal-title":"Bioessays"},{"key":"2023090508443947800_dmad010-B171","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1093\/molehr\/gan065","article-title":"Metabolism of the viable mammalian embryo: quietness revisited","volume":"14","author":"Leese","year":"2008","journal-title":"Mol Hum Reprod"},{"key":"2023090508443947800_dmad010-B172","doi-asserted-by":"crossref","first-page":"899485","DOI":"10.3389\/fphys.2022.899485","article-title":"The quiet embryo hypothesis: 20 years on","volume":"13","author":"Leese","year":"2022","journal-title":"Front Physiol"},{"key":"2023090508443947800_dmad010-B173","doi-asserted-by":"crossref","first-page":"e027767","DOI":"10.1136\/bmjopen-2018-027767","article-title":"Going to extremes: the Goldilocks\/Lagom principle and data distribution","volume":"9","author":"Leese","year":"2019","journal-title":"BMJ Open"},{"key":"2023090508443947800_dmad010-B174","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1093\/humrep\/dem253","article-title":"Embryo viability and metabolism: obeying the quiet rules","volume":"22","author":"Leese","year":"2007","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B175","doi-asserted-by":"crossref","first-page":"205","DOI":"10.4103\/2096-2924.274544","article-title":"Retrospective cohort study of preimplantation genetic testing for aneuploidy with comprehensive chromosome screening versus nonpreimplantation genetic testing in normal karyotype, secondary infertility patients with recurrent pregnancy loss","volume":"3","author":"Lei","year":"2019","journal-title":"Reprod Dev Med"},{"key":"2023090508443947800_dmad010-B176","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1056\/NEJMoa1808737","article-title":"A randomized trial of endometrial scratching before in vitro fertilization","volume":"380","author":"Lensen","year":"2019","journal-title":"N Engl J Med"},{"key":"2023090508443947800_dmad010-B177","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.fertnstert.2019.11.016","article-title":"Higher chromosomal abnormality rate in blastocysts from young patients with idiopathic recurrent pregnancy loss","volume":"113","author":"Liu","year":"2020","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B178","doi-asserted-by":"crossref","first-page":"hoy023","DOI":"10.1093\/hropen\/hoy023","article-title":"Comprehensive mitochondrial DNA analysis and IVF outcome","volume":"2018","author":"Lledo","year":"2018","journal-title":"Hum Reprod Open"},{"key":"2023090508443947800_dmad010-B179","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.rbmo.2017.07.010","article-title":"Early miscarriage rate in lean polycystic ovary syndrome women after euploid embryo transfer \u2013 a matched-pair study","volume":"35","author":"Luo","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B180","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s13039-016-0238-8","article-title":"A pilot proof-of-principle study to compare fresh and vitrified cycle preimplantation genetic screening by chromosome microarray and next generation sequencing","volume":"9","author":"Ma","year":"2016","journal-title":"Mol Cytogenet"},{"key":"2023090508443947800_dmad010-B181","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1095\/biolreprod.114.122846","article-title":"The human endometrium as a sensor of embryo quality","volume":"91","author":"Macklon","year":"2014","journal-title":"Biol Reprod"},{"key":"2023090508443947800_dmad010-B182","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/humrep\/dez234","article-title":"The effect of ICSI-related procedural timings and operators on the outcome","volume":"35","author":"Maggiulli","year":"2020","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B183","doi-asserted-by":"publisher","DOI":"10.3791\/59625","article-title":"Human blastocyst biopsy and vitrification","author":"Maggiulli","year":"2019","journal-title":"J Vis Exp"},{"key":"2023090508443947800_dmad010-B184","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.fertnstert.2018.09.016","article-title":"Deoxyribonucleic acid detection in blastocoelic fluid: a new predictor of embryo ploidy and viable pregnancy","volume":"111","author":"Magli","year":"2019","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B185","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s10815-019-01646-z","article-title":"Pregnancy outcomes after frozen-thawed single euploid blastocyst transfer following IVF cycles using GNRH agonist or HCG trigger for final oocyte maturation","volume":"37","author":"Makhijani","year":"2020","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B186","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.fertnstert.2010.07.1088","article-title":"Ovarian stimulation and the risk of aneuploid conceptions","volume":"95","author":"Massie","year":"2011","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B187","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1093\/humupd\/dmr003","article-title":"Preimplantation genetic screening: a systematic review and meta-analysis of RCTs","volume":"17","author":"Mastenbroek","year":"2011","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B188","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s10815-017-0937-z","article-title":"Could monopronucleated ICSI zygotes be considered for transfer? Analysis through time-lapse monitoring and PGS","volume":"34","author":"Mateo","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B189","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.fertnstert.2017.08.033","article-title":"Effect of the male factor on the clinical outcome of intracytoplasmic sperm injection combined with preimplantation aneuploidy testing: observational longitudinal cohort study of 1,219 consecutive cycles","volume":"108","author":"Mazzilli","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B190","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/j.fertnstert.2005.05.063","article-title":"Pregnancies and live births after trophectoderm biopsy and preimplantation genetic testing of human blastocysts","volume":"84","author":"McArthur","year":"2005","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B191","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.fertnstert.2020.08.021","article-title":"Can embryo morphokinetic parameters predict euploid pregnancy loss?","volume":"115","author":"McQueen","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B192","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1007\/s10815-017-0983-6","article-title":"Replacing single frozen-thawed euploid embryos in a natural cycle in ovulatory women may increase live birth rates compared to medicated cycles in anovulatory women","volume":"34","author":"Melnick","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B193","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s10815-020-01996-z","article-title":"Live birth rate from euploid blastocysts is not associated with infertility etiology or oocyte source following frozen-thawed embryo transfer (FET): analysis of 4148 cycles reported to SART CORS","volume":"38","author":"Meng","year":"2021","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B194","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1093\/humrep\/dew183","article-title":"Correlation between aneuploidy, standard morphology evaluation and morphokinetic development in 1730 biopsied blastocysts: a consecutive case series study","volume":"31","author":"Minasi","year":"2016","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B195","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/GCO.0000000000000449","article-title":"The dilemma of aneuploidy screening on low responders","volume":"30","author":"Morin","year":"2018","journal-title":"Curr Opin Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B196","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1093\/humrep\/dey238","article-title":"Diminished ovarian reserve and poor response to stimulation in patients <38 years old: a quantitative but not qualitative reduction in performance","volume":"33","author":"Morin","year":"2018","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B197","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1007\/s10815-021-02250-w","article-title":"Embryo quality, ploidy, and transfer outcomes in male versus female blastocysts","volume":"38","author":"Moutos","year":"2021","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B198","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.rbmo.2017.08.025","article-title":"Duration of blastulation may be associated with ongoing pregnancy rate in single euploid blastocyst transfer cycles","volume":"35","author":"Mumusoglu","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B199","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1093\/humrep\/dex031","article-title":"Euploidy rates in donor egg cycles significantly differ between fertility centres","volume":"32","author":"Munne","year":"2017","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B200","first-page":"113","article-title":"Prognostic value of blastocyst grade after frozen euploid embryo transfer in patients with recurrent pregnancy loss","volume":"1","author":"Murugappan","year":"2020","journal-title":"F S Rep"},{"key":"2023090508443947800_dmad010-B201","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.rbmo.2018.10.007","article-title":"The correlation between morphology and implantation of euploid human blastocysts","volume":"38","author":"Nazem","year":"2019","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B202","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/uog.22065","article-title":"Three-dimensional ultrasound diagnosis of adenomyosis is not associated with adverse pregnancy outcome following single thawed euploid blastocyst transfer: prospective cohort study","volume":"56","author":"Neal","year":"2020","journal-title":"Ultrasound Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B203","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.fertnstert.2016.11.013","article-title":"High relative deoxyribonucleic acid content of trophectoderm biopsy adversely affects pregnancy outcomes","volume":"107","author":"Neal","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B204","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1007\/s10815-019-01550-6","article-title":"When next-generation sequencing-based preimplantation genetic testing for aneuploidy (PGT-A) yields an inconclusive report: diagnostic results and clinical outcomes after re biopsy","volume":"36","author":"Neal","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B205","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/humupd\/dms043","article-title":"The ageing ovary and uterus: new biological insights","volume":"19","author":"Nelson","year":"2013","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B206","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1007\/s10815-019-01535-5","article-title":"What is the clinical impact of the endometrial receptivity array in PGT-A and oocyte donation cycles?","volume":"36","author":"Neves","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B207","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s10815-020-01722-9","article-title":"Comprehensive analysis of the associations between previous pregnancy failures and blastocyst aneuploidy as well as pregnancy outcomes after PGT-A","volume":"37","author":"Ni","year":"2020","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B208","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.rbmo.2021.02.005","article-title":"Comparison of single euploid blastocyst transfer cycle outcome derived from embryos with normal or abnormal cleavage patterns","volume":"42","author":"Ozbek","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B209","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10815-018-1347-6","article-title":"Minimizing mosaicism: assessing the impact of fertilization method on rate of mosaicism after next-generation sequencing (NGS) preimplantation genetic testing for aneuploidy (PGT-A)","volume":"36","author":"Palmerola","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B210","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1007\/s10815-021-02197-y","article-title":"Elevated serum progesterone does not impact euploidy rates in PGT-A patients","volume":"38","author":"Pardi\u00f1as","year":"2021","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B211","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.rbmo.2016.02.002","article-title":"Corona cell RNA sequencing from individual oocytes revealed transcripts and pathways linked to euploid oocyte competence and live birth","volume":"32","author":"Parks","year":"2016","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B212","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.repbio.2020.08.002","article-title":"Effects of euploid blastocyst morphological development on reproductive outcomes","volume":"20","author":"Peng","year":"2020","journal-title":"Reprod Biol"},{"key":"2023090508443947800_dmad010-B213","doi-asserted-by":"crossref","first-page":"3541","DOI":"10.15419\/bmrat.v6i12.581","article-title":"Selecting euploid embryo for transfer by preimplantation genetic testing for aneuploidy improved clinical outcomes in patients with advanced maternal age","volume":"6","author":"Phuong","year":"2019","journal-title":"Biomed Res Ther"},{"key":"2023090508443947800_dmad010-B214","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.rbmo.2016.06.005","article-title":"Does slow embryo development predict a high aneuploidy rate on trophectoderm biopsy?","volume":"33","author":"Piccolomini","year":"2016","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B215","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.rbmo.2021.03.006","article-title":"Serum anti-Mullerian hormone levels are not associated with aneuploidy rates in human blastocysts","volume":"42","author":"Pipari","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B216","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.fertnstert.2020.07.002","article-title":"Rate of true recurrent implantation failure is low: results of three successive frozen euploid single embryo transfers","volume":"115","author":"Pirtea","year":"2020","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B217","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1007\/s10815-019-01574-y","article-title":"Deconstructing the myth of poor prognosis for fast-cleaving embryos on day 3. Is it time to change the consensus?","volume":"36","author":"Pons","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B218","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1093\/humrep\/dez012","article-title":"Extended in vitro culture of human embryos demonstrates the complex nature of diagnosing chromosomal mosaicism from a single trophectoderm biopsy","volume":"34","author":"Popovic","year":"2019","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B219","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1093\/humrep\/dex070","article-title":"Mitochondrial DNA quantification as a tool for embryo viability assessment: retrospective analysis of data from single euploid blastocyst transfers","volume":"32","author":"Ravichandran","year":"2017","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B220","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s10815-020-01739-0","article-title":"The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers","volume":"37","author":"Reig","year":"2020","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B221","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.fertnstert.2019.07.1322","article-title":"Time of morulation and trophectoderm quality are predictors of a live birth after euploid blastocyst transfer: a multicentre study","volume":"112","author":"Rienzi","year":"2019","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B222","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1093\/humrep\/deaa009","article-title":"Definition of a clinical strategy to enhance the efficacy, efficiency and safety of egg donation cycles with imported vitrified oocytes","volume":"35","author":"Rienzi","year":"2020","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B223","first-page":"139","article-title":"Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance","volume":"23","author":"Rienzi","year":"2017","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B224","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1007\/s10815-015-0507-1","article-title":"Oocyte versus embryo cryopreservation for fertility preservation in cancer patients: guaranteeing a women\u2019s autonomy","volume":"32","author":"Rienzi","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B225","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.fertnstert.2020.09.140","article-title":"Routine endometrial receptivity array in first embryo transfer cycles does not improve live birth rate","volume":"115","author":"Riestenberg","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B226","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s10815-020-02043-7","article-title":"Endometrial compaction does not predict live birth rate in single euploid frozen embryo transfer cycles","volume":"38","author":"Riestenberg","year":"2021","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B227","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1007\/s10815-018-1265-7","article-title":"Euploid embryos selected by an automated time-lapse system have superior SET outcomes than selected solely by conventional morphology assessment","volume":"35","author":"Rocafort","year":"2018","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B228","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s10815-016-0647-y","article-title":"Reproductive outcome is optimized by genomic embryo screening, vitrification, and subsequent transfer into a prepared synchronous endometrium","volume":"33","author":"Rodriguez-Purata","year":"2016","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B229","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1093\/humrep\/deab111","article-title":"Length of estradiol exposure >100 pg\/ml in the follicular phase affects pregnancy outcomes in natural frozen embryo transfer cycles","volume":"36","author":"Romanski","year":"2021","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B230","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.fertnstert.2018.06.002","article-title":"The pros and cons of preimplantation genetic testing for aneuploidy: clinical and laboratory perspectives","volume":"110","author":"Rosenwaks","year":"2018","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B231","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.fertnstert.2019.12.034","article-title":"Trophectoderm biopsy protocols can affect clinical outcomes: time to focus on the blastocyst biopsy technique","volume":"113","author":"Rubino","year":"2020","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B232","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S1472-6483(10)60015-6","article-title":"Prognostic factors for preimplantation genetic screening in repeated pregnancy loss","volume":"18","author":"Rubio","year":"2009","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B233","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1093\/humrep\/deq174","article-title":"Prospective cohort study in high responder oocyte donors using two hormonal stimulation protocols: impact on embryo aneuploidy and development","volume":"25","author":"Rubio","year":"2010","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B234","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.fertnstert.2019.04.038","article-title":"Embryonic cell-free DNA versus trophectoderm biopsy for aneuploidy testing: concordance rate and clinical implications","volume":"112","author":"Rubio","year":"2019","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B235","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1007\/s10815-019-01609-4","article-title":"Preimplantation genetic testing for aneuploidy improves clinical, gestational, and neonatal outcomes in advanced maternal age patients without compromising cumulative live-birth rate","volume":"36","author":"Sacchi","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B236","doi-asserted-by":"crossref","first-page":"652","DOI":"10.4103\/1119-3077.208959","article-title":"To compare aneuploidy rates between ICSI and IVF Cases","volume":"20","author":"Sahin","year":"2017","journal-title":"Niger J Clin Pract"},{"key":"2023090508443947800_dmad010-B237","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.fertnstert.2009.10.046","article-title":"Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis","volume":"93","author":"Sakkas","year":"2010","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B238","doi-asserted-by":"crossref","first-page":"155","DOI":"10.4103\/jhrs.JHRS_115_19","article-title":"The influence of delayed blastocyst development on the outcome of frozen-thawed transfer of euploid and untested embryos","volume":"13","author":"Sardana","year":"2020","journal-title":"J Hum Reprod Sci"},{"key":"2023090508443947800_dmad010-B239","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1093\/humrep\/dez229","article-title":"Preimplantation genetic testing for aneuploidy: a comparison of live birth rates in patients with recurrent pregnancy loss due to embryonic aneuploidy or recurrent implantation failure","volume":"34","author":"Sato","year":"2019","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B240","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1007\/s10815-019-01410-3","article-title":"An integrated investigation of oocyte developmental competence: expression of key genes in human cumulus cells, morphokinetics of early divisions, blastulation, and euploidy","volume":"36","author":"Scarica","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B241","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/S0015-0282(99)00311-8","article-title":"Blastocyst culture and transfer: analysis of results and parameters affecting outcome in two in vitro fertilization programs","volume":"72","author":"Schoolcraft","year":"1999","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B242","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.fertnstert.2012.01.104","article-title":"Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study","volume":"97","author":"Scott","year":"2012","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B243","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.rbmo.2020.04.011","article-title":"Mitochondrial DNA content is not predictive of reproductive competence in euploid blastocysts","volume":"41","author":"Scott","year":"2020","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B244","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.fertnstert.2013.04.039","article-title":"Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial","volume":"100","author":"Scott","year":"2013","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B245","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.fertnstert.2019.02.024","article-title":"Endometrial preparation before the transfer of single, vitrified-warmed, euploid blastocysts: does the duration of estradiol treatment influence clinical outcome?","volume":"111","author":"Sekhon","year":"2019","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B246","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.ajog.2014.11.022","article-title":"A biochemical view: vitamin D levels do not affect in vitro fertilization outcomes following the transfer of euploid blastocysts","volume":"212","author":"Sertoglu","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"2023090508443947800_dmad010-B247","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.fertnstert.2019.12.007","article-title":"Frozen-thawed embryo transfer: the potential importance of the corpus luteum in preventing obstetrical complications","volume":"113","author":"Singh","year":"2020","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B248","first-page":"CD011872","article-title":"Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies","volume":"5","author":"Siristatidis","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"2023090508443947800_dmad010-B249","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/humrep\/12.2.321","article-title":"The chromosomal constitution of embryos developing from abnormally fertilized oocytes after intracytoplasmic sperm injection and conventional in-vitro fertilization","volume":"12","author":"Staessen","year":"1997","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B250","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1089\/thy.2011.0087","article-title":"Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum","volume":"21","author":"Stagnaro-Green","year":"2011","journal-title":"Thyroid"},{"key":"2023090508443947800_dmad010-B251","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.fertnstert.2017.12.001","article-title":"Arcuate uterus: is there an impact on in vitro fertilization outcomes after euploid embryo transfer?","volume":"109","author":"Surrey","year":"2018","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B252","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1007\/s10815-020-01842-2","article-title":"GnRH triggering may improve euploidy and live birth rate in hyper-responders: a retrospective cohort study","volume":"37","author":"Tan","year":"2020","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B253","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1007\/s10815-017-1112-2","article-title":"The role of the endometrial receptivity array (ERA) in patients who have failed euploid embryo transfers","volume":"35","author":"Tan","year":"2018","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B254","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1007\/s10815-019-01584-w","article-title":"Male factor infertility impacts the rate of mosaic blastocysts in cycles of preimplantation genetic testing for aneuploidy","volume":"36","author":"Tarozzi","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B255","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.fertnstert.2014.07.1207","article-title":"Blastocyst euploidy and implantation rates in a young (<35 years) and old (>\/\u2009=\u200935 years) presumed fertile and infertile patient population","volume":"102","author":"Taylor","year":"2014","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B256","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.rbmo.2014.03.001","article-title":"Outcomes of blastocysts biopsied and vitrified once versus those cryopreserved twice for euploid blastocyst transfer","volume":"29","author":"Taylor","year":"2014","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B257","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.rbmo.2014.06.001","article-title":"Comparison of aneuploidy, pregnancy and live birth rates between day 5 and day 6 blastocysts","volume":"29","author":"Taylor","year":"2014","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B258","doi-asserted-by":"crossref","first-page":"e10258","DOI":"10.1371\/journal.pone.0010258","article-title":"Natural selection of human embryos: decidualizing endometrial stromal cells serve as sensors of embryo quality upon implantation","volume":"5","author":"Teklenburg","year":"2010","journal-title":"PLoS One"},{"key":"2023090508443947800_dmad010-B259","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/humrep\/deh579","article-title":"ESHRE PGD Consortium \u2018Best practice guidelines for clinical preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS)\u2019","volume":"20","author":"Thornhill","year":"2005","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B260","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1177\/1933719116687660","article-title":"Paternal age is not associated with pregnancy outcomes after single thawed euploid blastocyst transfer","volume":"24","author":"Tiegs","year":"2017","journal-title":"Reprod Sci"},{"key":"2023090508443947800_dmad010-B261","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.fertnstert.2020.07.052","article-title":"A multicentre, prospective, blinded, nonselection study evaluating the predictive value of an aneuploid diagnosis using a targeted next-generation sequencing-based preimplantation genetic testing for aneuploidy assay and impact of biopsy","volume":"115","author":"Tiegs","year":"2020","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B262","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1007\/s43032-021-00519-0","article-title":"Next-generation sequencing (NGS)-based preimplantation genetic testing for aneuploidy (PGT-A) of trophectoderm biopsy for recurrent implantation failure (RIF) patients: a retrospective study","volume":"28","author":"Tong","year":"2021","journal-title":"Reprod Sci"},{"key":"2023090508443947800_dmad010-B263","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/molehr\/gaq103","article-title":"Single-cell whole-genome amplification technique impacts the accuracy of SNP microarray-based genotyping and copy number analyses","volume":"17","author":"Treff","year":"2011","journal-title":"Mol Hum Reprod"},{"key":"2023090508443947800_dmad010-B264","first-page":"954","article-title":"Levels of trophectoderm mitochondrial DNA do not predict the reproductive potential of sibling embryos","volume":"32","author":"Treff","year":"2017","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B265","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1093\/humrep\/dev159","article-title":"Reduction of multiple pregnancies in the advanced maternal age population after implementation of an elective single embryo transfer policy coupled with enhanced embryo selection: pre- and post-intervention study","volume":"30","author":"Ubaldi","year":"2015","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B266","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1016\/j.fertnstert.2016.03.002","article-title":"Follicular versus luteal phase ovarian stimulation during the same menstrual cycle (DuoStim) in a reduced ovarian reserve population results in a similar euploid blastocyst formation rate: new insight in ovarian reserve exploitation","volume":"105","author":"Ubaldi","year":"2016","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B267","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1093\/humrep\/deaa203","article-title":"The euploid blastocysts obtained after luteal phase stimulation show the same clinical, obstetric and perinatal outcomes as follicular phase stimulation-derived ones: a multicentre study","volume":"35","author":"Vaiarelli","year":"2020","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B268","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ejogrb.2020.11.024","article-title":"Endometriosis shows no impact on the euploid blastocyst rate per cohort of inseminated metaphase-II oocytes: a case\u2013control study","volume":"256","author":"Vaiarelli","year":"2021","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2023090508443947800_dmad010-B269","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.fertnstert.2017.05.033","article-title":"Implantation failure of endometrial origin: it is not pathology, but our failure to synchronize the developing embryo with a receptive endometrium","volume":"108","author":"Valdes","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B270","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1017\/S0967199400003920","article-title":"Laser blastocyst biopsy for preimplantation diagnosis in the human","volume":"5","author":"Veiga","year":"1997","journal-title":"Zygote"},{"key":"2023090508443947800_dmad010-B271","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.fertnstert.2016.09.028","article-title":"Accurate quantitation of mitochondrial DNA reveals uniform levels in human blastocysts irrespective of ploidy, age, or implantation potential","volume":"107","author":"Victor","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B272","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1007\/s10815-018-1246-x","article-title":"Contraction behaviour reduces embryo competence in high-quality euploid blastocysts","volume":"35","author":"Vinals Gonzalez","year":"2018","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B273","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1007\/s10815-019-01496-9","article-title":"Euploid blastocysts implant irrespective of their morphology after NGS-(PGT-A) testing in advanced maternal age patients","volume":"36","author":"Vinals Gonzalez","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B274","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/humupd\/dmv034","article-title":"The effects of chemical and physical factors on mammalian embryo culture and their importance for the practice of assisted human reproduction","volume":"22","author":"Wale","year":"2016","journal-title":"Hum Reprod Update"},{"key":"2023090508443947800_dmad010-B275","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.rbmo.2019.05.011","article-title":"Miscarriage history association with euploid embryo transfer outcomes","volume":"39","author":"Wang","year":"2019","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B276","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.rbmo.2019.05.006","article-title":"Anti-Mullerian hormone in association with euploid embryo transfer outcomes","volume":"39","author":"Wang","year":"2019","journal-title":"Reprod Biomed Online"},{"key":"2023090508443947800_dmad010-B277","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1007\/s00404-019-05251-4","article-title":"Hormone replacement versus natural frozen embryo transfer for euploid embryos","volume":"300","author":"Wang","year":"2019","journal-title":"Arch Gynecol Obstet"},{"key":"2023090508443947800_dmad010-B278","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1089\/dna.2020.6271","article-title":"Trophectoderm mitochondrial DNA content associated with embryo quality and day-5 euploid blastocyst transfer outcomes","volume":"40","author":"Wang","year":"2021","journal-title":"DNA Cell Biol"},{"key":"2023090508443947800_dmad010-B279","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.fertnstert.2021.01.034","article-title":"Embryo-endometrium crosstalk: a new understanding from in vitro model","volume":"115","author":"Wang","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B280","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s10815-015-0435-0","article-title":"Endometrial disruption does not improve implantation in patients who have failed the transfer of euploid blastocysts","volume":"32","author":"Werner","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B281","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.fertnstert.2016.01.005","article-title":"Sequential versus Monophasic Media Impact Trial (SuMMIT): a paired randomized controlled trial comparing a sequential media system to a monophasic medium","volume":"105","author":"Werner","year":"2016","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B282","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1093\/humrep\/deac058","article-title":"Sperm selection with hyaluronic acid improved live birth outcomes among older couples and was connected to sperm DNA quality, potentially affecting all treatment outcomes","volume":"37","author":"West","year":"2022","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B283","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1095\/biolreprod.116.144410","article-title":"Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment","volume":"96","author":"Wetendorf","year":"2017","journal-title":"Biol Reprod"},{"key":"2023090508443947800_dmad010-B284","first-page":"45","article-title":"Day 7 blastocyst euploidy supports routine implementation for cycles using preimplantation genetic testing","volume":"23","author":"Whitney","year":"2019","journal-title":"JBRA Assist Reprod"},{"key":"2023090508443947800_dmad010-B285","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1093\/humrep\/deab064","article-title":"The true incidence of chromosomal mosaicism after preimplantation genetic testing is much lower than that indicated by trophectoderm biopsy","volume":"36","author":"Wu","year":"2021","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B286","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1093\/humrep\/dey270","article-title":"Dosage of exogenous gonadotropins is not associated with blastocyst aneuploidy or live-birth rates in PGS cycles in Chinese women","volume":"33","author":"Wu","year":"2018","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B287","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1017\/S0967199420000866","article-title":"Prolonged interval time between blastocyst biopsy and vitrification compromised the outcomes in preimplantation genetic testing","volume":"29","author":"Xiong","year":"2021","journal-title":"Zygote"},{"key":"2023090508443947800_dmad010-B288","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/s10815-021-02137-w","article-title":"Trophectoderm biopsy protocols may impact the rate of mosaic blastocysts in cycles with pre-implantation genetic testing for aneuploidy","volume":"38","author":"Xiong","year":"2021","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B289","doi-asserted-by":"crossref","first-page":"3540","DOI":"10.1093\/humrep\/des330","article-title":"Administration of calcitonin promotes blastocyst implantation in mice by up-regulating integrin beta3 expression in endometrial epithelial cells","volume":"27","author":"Xiong","year":"2012","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B290","doi-asserted-by":"crossref","first-page":"e13107","DOI":"10.1111\/aji.13107","article-title":"Lipoxin A4 interferes with embryo implantation via suppression of epithelial-mesenchymal transition","volume":"81","author":"Xu","year":"2019","journal-title":"Am J Reprod Immunol"},{"key":"2023090508443947800_dmad010-B291","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1056\/NEJMoa2103613","article-title":"Live birth with or without preimplantation genetic testing for aneuploidy","volume":"385","author":"Yan","year":"2021","journal-title":"N Engl J Med"},{"key":"2023090508443947800_dmad010-B292","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1755-8794-7-38","article-title":"Selection of competent blastocysts for transfer by combining time-lapse monitoring and array CGH testing for patients undergoing preimplantation genetic screening: a prospective study with sibling oocytes","volume":"7","author":"Yang","year":"2014","journal-title":"BMC Med Genomics"},{"key":"2023090508443947800_dmad010-B293","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1007\/s10815-019-01517-7","article-title":"A prospective study of non-invasive preimplantation genetic testing for aneuploidies (NiPGT-A) using next-generation sequencing (NGS) on spent culture media (SCM)","volume":"36","author":"Yeung","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443947800_dmad010-B294","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1093\/humrep\/dex234","article-title":"The international glossary on infertility and fertility care, 2017","volume":"32","author":"Zegers-Hochschild","year":"2017","journal-title":"Hum Reprod"},{"key":"2023090508443947800_dmad010-B295","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.fertnstert.2017.06.005","article-title":"The international glossary on infertility and fertility care, 2017","volume":"108","author":"Zegers-Hochschild","year":"2017","journal-title":"Fertil Steril"},{"key":"2023090508443947800_dmad010-B296","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1007\/s00404-019-05084-1","article-title":"Comparison of two protocols of blastocyst biopsy submitted to preimplantation genetic testing for aneuploidies: a randomized controlled trial","volume":"299","author":"Zhao","year":"2019","journal-title":"Arch Gynecol Obstet"},{"key":"2023090508443947800_dmad010-B297","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.4103\/0366-6999.232808","article-title":"Overall blastocyst quality, trophectoderm grade, and inner cell mass grade predict pregnancy outcome in euploid blastocyst transfer cycles","volume":"131","author":"Zhao","year":"2018","journal-title":"Chin Med J (Engl)"},{"key":"2023090508443947800_dmad010-B298","doi-asserted-by":"crossref","first-page":"762976","DOI":"10.3389\/fendo.2021.762976","article-title":"Mitochondrial DNA content may not be a reliable screening biomarker for live birth after single euploid blastocyst transfer","volume":"12","author":"Zhou","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2023090508443947800_dmad010-B299","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.fertnstert.2019.12.030","article-title":"Endometrial compaction before frozen euploid embryo transfer improves ongoing pregnancy rates","volume":"113","author":"Zilberberg","year":"2020","journal-title":"Fertil Steril"}],"container-title":["Human Reproduction Update"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/humupd\/article-pdf\/29\/5\/570\/51344812\/dmad010.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/humupd\/article-pdf\/29\/5\/570\/51344812\/dmad010.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T04:48:14Z","timestamp":1693889294000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humupd\/article\/29\/5\/570\/7165696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,16]]},"references-count":299,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5,16]]},"published-print":{"date-parts":[[2023,9,5]]}},"URL":"https:\/\/doi.org\/10.1093\/humupd\/dmad010","relation":{},"ISSN":["1355-4786","1460-2369"],"issn-type":[{"value":"1355-4786","type":"print"},{"value":"1460-2369","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,10,1]]},"published":{"date-parts":[[2023,5,16]]}}}