{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:39:42Z","timestamp":1793378382014,"version":"4.5.0"},"reference-count":88,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T00:00:00Z","timestamp":1683849600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"Netherlands Organisation for Health Research and Development","doi-asserted-by":"publisher","award":["ZonMw 843002807"],"award-info":[{"award-number":["ZonMw 843002807"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Antarctica-2 RCT","award":["NTR6590"],"award-info":[{"award-number":["NTR6590"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>The number of frozen embryo transfers (FET) has increased dramatically over the past decade. Based on current evidence, there is no difference in pregnancy rates when natural cycle FET (NC-FET) is compared to artificial cycle FET (AC-FET) in subfertile women. However, NC-FET seems to be associated with lower risk of adverse obstetric and neonatal outcomes compared with AC-FET cycles. Currently, there is no consensus about whether NC-FET needs to be combined with luteal phase support (LPS) or not. The question of how to prepare the endometrium for FET has now gained even more importance and taken the dimension of safety into account as it should not simply be reduced to the basic question of effectiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE AND RATIONALE<\/jats:title>\n                    <jats:p>The objective of this project was to determine whether NC-FET, with or without LPS, decreases the risk of adverse obstetric and neonatal outcomes compared with AC-FET.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SEARCH METHODS<\/jats:title>\n                    <jats:p>A systematic review and meta-analysis was carried out. A literature search was performed using the following databases: CINAHL, EMBASE, and MEDLINE from inception to 10 October 2022. Observational studies, including cohort studies, and registries comparing obstetric and neonatal outcomes between singleton pregnancies after NC-FET and those after AC-FET were sought. Risk of bias was assessed using the ROBINS-I tool. The quality of evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation approach. We calculated pooled odds ratios (ORs), pooled risk differences (RDs), pooled adjusted ORs, and prevalence estimates with 95% CI using a random effect model, while heterogeneity was assessed by the I2.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OUTCOMES<\/jats:title>\n                    <jats:p>The conducted search identified 2436 studies, 890 duplicates were removed and 1546 studies were screened. Thirty studies (NC-FET n\u2009=\u200956\u200a445; AC-FET n\u2009=\u200957\u200a231) were included, 19 of which used LPS in NC-FET. Birthweight was lower following NC-FET versus AC-FET (mean difference 26.35\u2009g; 95% CI 11.61\u201341.08, I2\u2009=\u200963%). Furthermore NC-FET compared to AC-FET resulted in a lower risk of large for gestational age (OR 0.88, 95% 0.83\u20130.94, I2\u2009=\u200954%), macrosomia (OR 0.81; 95% CI 0.71\u20130.93, I2\u2009=\u200968%), low birthweight (OR 0.81, 95% CI 0.77\u20130.85, I2\u2009=\u200941%), early pregnancy loss (OR 0.73; 95% CI 0.61\u20130.86, I2\u2009=\u200970%), preterm birth (OR 0.80; 95% CI 0.75\u20130.85, I2\u2009=\u200920%), very preterm birth (OR 0.66, 95% CI 0.53\u20130.84, I2\u2009=\u20090%), hypertensive disorders of pregnancy (OR 0.60, 95% CI 0.50\u20130.65, I2\u2009=\u200961%), pre-eclampsia (OR 0.50; 95% CI 0.42\u20130.60, I2\u2009=\u200944%), placenta previa (OR 0.84, 95% CI 0.73\u20130.97, I2\u2009=\u20090%), and postpartum hemorrhage (OR 0.43; 95% CI 0.38\u20130.48, I2\u2009=\u200953%). Stratified analyses on LPS use in NC-FET suggested that, compared to AC-FET, NC-FET with LPS decreased preterm birth risk, while NC-FET without LPS did not (OR 0.75, 95% CI 0.70\u20130.81). LPS use did not modify the other outcomes. Heterogeneity varied from low to high, while quality of the evidence was very low to moderate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>WIDER IMPLICATIONS<\/jats:title>\n                    <jats:p>This study confirms that NC-FET decreases the risk of adverse obstetric and neonatal outcomes compared with AC-FET. We estimate that for each adverse outcome, use of NC-FET may prevent 4 to 22 cases per 1000 women. Consequently, NC-FET should be the preferred treatment in women with ovulatory cycles undergoing FET. Based on very low quality of evidence, the risk of preterm birth be decreased when LPS is used in NC-FET compared to AC-FET. However, because of many uncertainties\u2014the major being the debate about efficacy of the use of LPS\u2014future research is needed on efficacy and safety of LPS and no recommendation can be made about the use of LPS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/humupd\/dmad011","type":"journal-article","created":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T15:57:35Z","timestamp":1683907055000},"page":"634-654","source":"Crossref","is-referenced-by-count":133,"title":["Obstetric and neonatal outcomes after natural versus artificial cycle frozen embryo transfer and the role of luteal phase support: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0673-3876","authenticated-orcid":false,"given":"T R","family":"Zaat","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC Location University of Amsterdam , Amsterdam, The Netherlands"},{"name":"Amsterdam Reproduction and Development Research Institute , Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E B","family":"Kostova","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC Location University of Amsterdam , Amsterdam, The Netherlands"},{"name":"Amsterdam Reproduction and Development Research Institute , Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Korsen","sequence":"additional","affiliation":[{"name":"University Medical Center Groningen , Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1227-4303","authenticated-orcid":false,"given":"M G","family":"Showell","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, University of Auckland , Auckland, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6892-5574","authenticated-orcid":false,"given":"F","family":"Mol","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC Location University of Amsterdam , Amsterdam, The Netherlands"},{"name":"Amsterdam Reproduction and Development Research Institute , Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8263-213X","authenticated-orcid":false,"given":"M","family":"van Wely","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC Location University of Amsterdam , Amsterdam, The Netherlands"},{"name":"Amsterdam Reproduction and Development Research Institute , Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,5,12]]},"reference":[{"key":"2023090508443629000_dmad011-B1","doi-asserted-by":"crossref","first-page":"e65","DOI":"10.1097\/AOG.0000000000004479","article-title":"Prediction and prevention of spontaneous preterm birth: ACOG Practice Bulletin, Number 234","volume":"138","author":"American College of Obstetricians and Gynecologists\u2019 Committee on Practice Bulletins\u2014Obstetrics","year":"2021","journal-title":"Obstet Gynecol"},{"key":"2023090508443629000_dmad011-B2","doi-asserted-by":"crossref","first-page":"703","DOI":"10.3390\/jcm10040703","article-title":"Ovulatory-based FET cycles may achieve higher pregnancy rates in the general population and among anovulatory women","volume":"10","author":"Aslih","year":"2021","journal-title":"J Clin Med"},{"key":"2023090508443629000_dmad011-B3","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.fertnstert.2020.10.039","article-title":"Adverse obstetric and perinatal outcomes in 1,136 singleton pregnancies conceived after programmed frozen embryo transfer (FET) compared with natural cycle FET","volume":"115","author":"Asserhoj","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443629000_dmad011-B4","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1472-6963-4-38","article-title":"Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group","volume":"4","author":"Atkins","year":"2004","journal-title":"BMC Health Serv Res"},{"key":"2023090508443629000_dmad011-B5","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.siny.2017.11.004","article-title":"Screening for fetal growth restriction and placental insufficiency","volume":"23","author":"Audette","year":"2018","journal-title":"Semin Fetal Neonatal Med"},{"key":"2023090508443629000_dmad011-B6","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.mce.2018.08.003","article-title":"Steroid hormones induce in vitro human first trimester trophoblast tubulogenesis by the lysophosphatidic acid pathway","volume":"478","author":"Beltrame","year":"2018","journal-title":"Mol Cell Endocrinol"},{"key":"2023090508443629000_dmad011-B7","doi-asserted-by":"crossref","first-page":"558819","DOI":"10.3389\/fendo.2020.558819","article-title":"Preterm birth in assisted reproductive technology: an analysis of more than 20,000 singleton newborns","volume":"11","author":"Bu","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2023090508443629000_dmad011-B8","doi-asserted-by":"crossref","first-page":"S745","DOI":"10.1016\/j.ajog.2017.11.577","article-title":"Pathophysiology of placental-derived fetal growth restriction","volume":"218","author":"Burton","year":"2018","journal-title":"Am J Obstet Gynecol"},{"key":"2023090508443629000_dmad011-B9","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1093\/humrep\/deac073","article-title":"Obstetric and perinatal outcomes following programmed compared to natural frozen-thawed embryo transfer cycles: a systematic review and meta-analysis","volume":"37","author":"Busnelli","year":"2022","journal-title":"Hum Reprod"},{"key":"2023090508443629000_dmad011-B10","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/j.fertnstert.2016.01.006","article-title":"Optimal endometrial preparation for frozen embryo transfer cycles: window of implantation and progesterone support","volume":"105","author":"Casper","year":"2016","journal-title":"Fertil Steril"},{"key":"2023090508443629000_dmad011-B11","doi-asserted-by":"crossref","first-page":"e0020","DOI":"10.5041\/RMMJ.10297","article-title":"Impact of endometrial preparation protocols for frozen embryo transfer on live birth rates","volume":"8","author":"Cerrillo","year":"2017","journal-title":"Rambam Maimonides Med J"},{"key":"2023090508443629000_dmad011-B12","doi-asserted-by":"crossref","first-page":"R69","DOI":"10.1152\/ajpregu.00239.2012","article-title":"Corpus luteal contribution to maternal pregnancy physiology and outcomes in assisted reproductive technologies","volume":"304","author":"Conrad","year":"2013","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"2023090508443629000_dmad011-B13","doi-asserted-by":"crossref","first-page":"E677","DOI":"10.1152\/ajpendo.00225.2019","article-title":"Potential influence of the corpus luteum on circulating reproductive and volume regulatory hormones, angiogenic and immunoregulatory factors in pregnant women","volume":"317","author":"Conrad","year":"2019","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"2023090508443629000_dmad011-B14","doi-asserted-by":"crossref","first-page":"R1091","DOI":"10.1152\/ajpregu.00015.2020","article-title":"Maternal endothelial function, circulating endothelial cells, and endothelial progenitor cells in pregnancies conceived with or without in vitro fertilization","volume":"318","author":"Conrad","year":"2020","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"2023090508443629000_dmad011-B15","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1161\/HYPERTENSIONAHA.119.13015","article-title":"Maternal cardiovascular dysregulation during early pregnancy after in vitro fertilization cycles in the absence of a corpus luteum","volume":"74","author":"Conrad","year":"2019","journal-title":"Hypertension"},{"key":"2023090508443629000_dmad011-B16","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.semnephrol.2010.10.003","article-title":"Emerging role of relaxin in the maternal adaptations to normal pregnancy: implications for preeclampsia","volume":"31","author":"Conrad","year":"2011","journal-title":"Semin Nephrol"},{"key":"2023090508443629000_dmad011-B17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta24330","article-title":"Progesterone to prevent miscarriage in women with early pregnancy bleeding: the PRISM RCT","volume":"24","author":"Coomarasamy","year":"2020","journal-title":"Health Technol Assess"},{"key":"2023090508443629000_dmad011-B18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta20410","article-title":"PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages\u2014a randomised, double-blind, placebo-controlled, international multicentre trial and economic evaluation","volume":"20","author":"Coomarasamy","year":"2016","journal-title":"Health Technol Assess"},{"key":"2023090508443629000_dmad011-B19","author":"Covidence systematic review software"},{"key":"2023090508443629000_dmad011-B20","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1080\/09513590.2021.1955342","article-title":"Endometrial preparation does not affect the risk of hypertensive disorders of pregnancy in low-risk women undergoing frozen embryo transfer","volume":"38","author":"Dallagiovanna","year":"2022","journal-title":"Gynecol Endocrinol"},{"key":"2023090508443629000_dmad011-B21","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1093\/humrep\/dey242","article-title":"ART in Europe, 2014: results generated from European registries by ESHRE: the European IVF-monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE)","volume":"33","author":"De Geyter","year":"2018","journal-title":"Hum Reprod"},{"key":"2023090508443629000_dmad011-B22","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1515\/jpm.2010.027","article-title":"Avoidable mortality in small-for-gestational-age children in the Netherlands","volume":"38","author":"De Reu","year":"2010","journal-title":"J Perinat Med"},{"key":"2023090508443629000_dmad011-B23","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1111\/1471-0528.14694","article-title":"Core outcome sets in women's and newborn health: a systematic review","volume":"124","author":"Duffy","year":"2017","journal-title":"BJOG"},{"key":"2023090508443629000_dmad011-B24","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.fertnstert.2020.11.012","article-title":"Developing a core outcome set for future infertility research: an international consensus development study","volume":"115","author":"Duffy","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443629000_dmad011-B25","doi-asserted-by":"crossref","first-page":"hoy007","DOI":"10.1093\/hropen\/hoy007","article-title":"A protocol developing, disseminating and implementing a core outcome set for infertility","volume":"2018","author":"Duffy","year":"2018","journal-title":"Hum Reprod Open"},{"key":"2023090508443629000_dmad011-B26","doi-asserted-by":"crossref","first-page":"126.e1","DOI":"10.1016\/j.ajog.2019.03.010","article-title":"Neonatal and maternal outcome after frozen embryo transfer: increased risks in programmed cycles","volume":"221","author":"Ernstad","year":"2019","journal-title":"Am J Obstet Gynecol"},{"key":"2023090508443629000_dmad011-B27","author":"ESHRE"},{"key":"2023090508443629000_dmad011-B28","doi-asserted-by":"crossref","first-page":"hoab026","DOI":"10.1093\/hropen\/hoab026","article-title":"ART in Europe, 2017: results generated from European registries by ESHRE","volume":"2021","author":"European IVF-Monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE)","year":"2021","journal-title":"Hum Reprod Open"},{"key":"2023090508443629000_dmad011-B29","first-page":"2282","article-title":"Perinatal and maternal outcome after vitrification of blastocysts: a Nordic study in singletons from the CoNARTaS group","volume":"34","author":"Ginstrom Ernstad","year":"2019","journal-title":"Hum Reprod"},{"key":"2023090508443629000_dmad011-B30","first-page":"CD006359","article-title":"Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes","volume":"10","author":"Glujovsky","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"2023090508443629000_dmad011-B31","doi-asserted-by":"crossref","first-page":"100752","DOI":"10.1016\/j.ajogmf.2022.100752","article-title":"Programmed frozen embryo transfer cycle increased risk of hypertensive disorders of pregnancy\u2014a multicenter cohort study in ovulatory women","volume":"5","author":"Gu","year":"2022","journal-title":"Am J Obstet Gynecol MFM"},{"key":"2023090508443629000_dmad011-B32","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1080\/19396368.2016.1199064","article-title":"A modified natural cycle results in higher live birth rate in vitrified-thawed embryo transfer for women with regular menstruation","volume":"62","author":"Guan","year":"2016","journal-title":"Syst Biol Reprod Med"},{"key":"2023090508443629000_dmad011-B33","first-page":"425","article-title":"Disparities in reproductive outcomes according to the endometrial preparation protocol in frozen embryo transfer: The risk of early pregnancy loss in frozen embryo transfer cycles.","volume":"35","author":"Hatoum","year":"2018"},{"key":"2023090508443629000_dmad011-B34","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"2023090508443629000_dmad011-B35","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1016\/j.fertnstert.2020.12.016","article-title":"Endometrium preparation and perinatal outcomes in women undergoing single-blastocyst transfer in frozen cycles","volume":"115","author":"Hu","year":"2021","journal-title":"Fertil Steril"},{"key":"2023090508443629000_dmad011-B36","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s10815-019-01420-1","article-title":"Increased pregnancy complications following frozen-thawed embryo transfer during an artificial cycle","volume":"36","author":"Jing","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443629000_dmad011-B37","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0015-0282(16)54416-1","article-title":"Relaxin levels in ovum donation pregnancies","volume":"56","author":"Johnson","year":"1991","journal-title":"Fertil Steril"},{"key":"2023090508443629000_dmad011-B38","doi-asserted-by":"crossref","first-page":"287.e1","DOI":"10.1016\/j.ajog.2016.12.029","article-title":"Failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta","volume":"216","author":"Labarrere","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"2023090508443629000_dmad011-B39","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1007\/s10815-015-0499-x","article-title":"Frozen blastocyst embryo transfer using a supplemented natural cycle protocol has a similar live birth rate compared to a programmed cycle protocol","volume":"32","author":"Lathi","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443629000_dmad011-B40","doi-asserted-by":"crossref","first-page":"346","DOI":"10.3389\/fendo.2020.00346","article-title":"Seven years of vitrified blastocyst transfers: comparison of 3 preparation protocols at a single ART center","volume":"11","author":"Levi Setti","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2023090508443629000_dmad011-B41","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1186\/s12884-021-03791-9","article-title":"Perinatal outcomes of neonates born from different endometrial preparation protocols after frozen embryo transfer: a retrospective cohort study","volume":"21","author":"Li","year":"2021","journal-title":"BMC Pregnancy Childbirth"},{"key":"2023090508443629000_dmad011-B42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/14647273.2022.2053593","article-title":"Maternal and child-health outcomes in different endometrial preparation methods for frozen-thawed embryo transfer: a retrospective study","author":"Li","year":"2022","journal-title":"Hum Fertil (Camb)"},{"key":"2023090508443629000_dmad011-B43","doi-asserted-by":"crossref","first-page":"338","DOI":"10.3389\/fmed.2020.00338","article-title":"Maternal and neonatal complications after natural vs. hormone replacement therapy cycle regimen for frozen single blastocyst transfer","volume":"7","author":"Lin","year":"2020","journal-title":"Front Med (Lausanne)"},{"key":"2023090508443629000_dmad011-B44","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/humupd\/dmx031","article-title":"Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer?","volume":"24","author":"Maheshwari","year":"2018","journal-title":"Hum Reprod Update"},{"key":"2023090508443629000_dmad011-B45","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.rbmo.2020.03.009","article-title":"Maternal and perinatal outcomes in programmed versus natural vitrified-warmed blastocyst transfer cycles","volume":"41","author":"Makhijani","year":"2020","journal-title":"Reprod Biomed Online"},{"key":"2023090508443629000_dmad011-B46","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.ejogrb.2022.07.021","article-title":"Practice variation in diagnosis, monitoring and management of fetal growth restriction in the Netherlands","volume":"276","author":"Marijnen","year":"2022","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2023090508443629000_dmad011-B47","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1093\/humupd\/dmab011","article-title":"Should women receive luteal support following natural cycle frozen embryo transfer? A systematic review and meta-analysis","volume":"27","author":"Mizrachi","year":"2021","journal-title":"Hum Reprod Update"},{"key":"2023090508443629000_dmad011-B48","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.rbmo.2021.03.002","article-title":"Lower risk of adverse perinatal outcomes in natural versus artificial frozen-thawed embryo transfer cycles: a systematic review and meta-analysis","volume":"42","author":"Moreno-Sepulveda","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"2023090508443629000_dmad011-B49","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1055\/s-0035-1570379","article-title":"Role of the placenta in preterm birth: a review","volume":"33","author":"Morgan","year":"2016","journal-title":"Am J Perinatol"},{"key":"2023090508443629000_dmad011-B50","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.fertnstert.2012.09.027","article-title":"Implications of assisted reproductive technologies on term singleton birth weight: an analysis of 25,777 children in the national assisted reproduction registry of Japan","volume":"99","author":"Nakashima","year":"2013","journal-title":"Fertil Steril"},{"key":"2023090508443629000_dmad011-B51","author":"NICE (National Institute for Health and Care Excellence)"},{"key":"2023090508443629000_dmad011-B52","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/humrep\/dev284","article-title":"Pregnancy complications in women with polycystic ovary syndrome: importance of diagnostic criteria or of phenotypic features?","volume":"31","author":"Palomba","year":"2016","journal-title":"Hum Reprod"},{"key":"2023090508443629000_dmad011-B53","doi-asserted-by":"crossref","first-page":"546532","DOI":"10.3389\/fendo.2020.546532","article-title":"Hormone replacement versus natural cycle protocols of endometrial preparation for frozen embryo transfer","volume":"11","author":"Pan","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2023090508443629000_dmad011-B54","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1093\/humupd\/dmab003","article-title":"Secretory products of the corpus luteum and preeclampsia","volume":"27","author":"Pereira","year":"2021","journal-title":"Hum Reprod Update"},{"key":"2023090508443629000_dmad011-B55","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/GRF.0000000000000456","article-title":"Fresh or frozen embryo transfer in in vitro fertilization: an update","volume":"62","author":"Pereira","year":"2019","journal-title":"Clin Obstet Gynecol"},{"key":"2023090508443629000_dmad011-B56","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1093\/humrep\/det440","article-title":"Large baby syndrome in singletons born after frozen embryo transfer (FET): is it due to maternal factors or the cryotechnique?","volume":"29","author":"Pinborg","year":"2014","journal-title":"Hum Reprod"},{"key":"2023090508443629000_dmad011-B57","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/aogs.12799","article-title":"Epigenetics and assisted reproductive technologies","volume":"95","author":"Pinborg","year":"2016","journal-title":"Acta Obstet Gynecol Scand"},{"key":"2023090508443629000_dmad011-B58","first-page":"575","article-title":"Fetal growth and body proportion in preeclampsia","volume":"101","author":"Rasmussen","year":"2003","journal-title":"Obstet Gynecol"},{"key":"2023090508443629000_dmad011-B59","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.rbmo.2021.12.004","article-title":"Artificially prepared vitrified-warmed embryo transfer cycles are associated with an increased risk of pre-eclampsia","volume":"44","author":"Roelens","year":"2022","journal-title":"Reprod Biomed Online"},{"key":"2023090508443629000_dmad011-B60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/humupd\/dmab037","article-title":"Effects of different frozen embryo transfer regimens on abnormalities of fetal weight: a systematic review and meta-analysis","volume":"28","author":"Rosalik","year":"2021","journal-title":"Hum Reprod Update"},{"key":"2023090508443629000_dmad011-B61","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1093\/humrep\/dez079","article-title":"Endometrial preparation methods for frozen-thawed embryo transfer are associated with altered risks of hypertensive disorders of pregnancy, placenta accreta, and gestational diabetes mellitus","volume":"34","author":"Saito","year":"2019","journal-title":"Hum Reprod"},{"key":"2023090508443629000_dmad011-B64","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s10815-017-0869-7","article-title":"Increased incidence of post-term delivery and Cesarean section after frozen-thawed embryo transfer during a hormone replacement cycle","volume":"34","author":"Saito","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"2023090508443629000_dmad011-B65","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/humupd\/dmw004","article-title":"The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding","volume":"22","author":"Schatz","year":"2016","journal-title":"Hum Reprod Update"},{"key":"2023090508443629000_dmad011-B66","doi-asserted-by":"crossref","first-page":"102167","DOI":"10.1016\/j.jogoh.2021.102167","article-title":"Frozen embryo transfer and preeclampsia risk","volume":"50","author":"Severino","year":"2021","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"2023090508443629000_dmad011-B67","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/ijgo.13852","article-title":"FIGO good practice recommendations on progestogens for prevention of preterm delivery","volume":"155","author":"Shennan","year":"2021","journal-title":"Int J Gynaecol Obstet"},{"key":"2023090508443629000_dmad011-B68","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1111\/1471-0528.16582","article-title":"The long-term effect of prenatal progesterone treatment on child development, behaviour and health: a systematic review","volume":"128","author":"Simons","year":"2021","journal-title":"BJOG"},{"key":"2023090508443629000_dmad011-B69","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.fertnstert.2019.12.007","article-title":"Frozen-thawed embryo transfer: the potential importance of the corpus luteum in preventing obstetrical complications","volume":"113","author":"Singh","year":"2020","journal-title":"Fertil Steril"},{"key":"2023090508443629000_dmad011-B70","doi-asserted-by":"crossref","first-page":"i4919","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"key":"2023090508443629000_dmad011-B71","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/305707a0","article-title":"Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo","volume":"305","author":"Trounson","year":"1983","journal-title":"Nature"},{"key":"2023090508443629000_dmad011-B72","doi-asserted-by":"crossref","first-page":"hoac007","DOI":"10.1093\/hropen\/hoac007","article-title":"Impact of endometrial preparation on early pregnancy loss and live birth rate after frozen embryo transfer: a large multicenter cohort study (14 421 frozen cycles)","volume":"2022","author":"Vinsonneau","year":"2022","journal-title":"Hum Reprod Open"},{"key":"2023090508443629000_dmad011-B73","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1161\/HYPERTENSIONAHA.118.12046","article-title":"Absent or excessive corpus luteum number is associated with altered maternal vascular health in early pregnancy","volume":"73","author":"von Versen-Hoynck","year":"2019","journal-title":"Hypertension"},{"key":"2023090508443629000_dmad011-B74","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1161\/HYPERTENSIONAHA.118.12043","article-title":"Increased preeclampsia risk and reduced aortic compliance with in vitro fertilization cycles in the absence of a corpus luteum","volume":"73","author":"von Versen-Hoynck","year":"2019","journal-title":"Hypertension"},{"key":"2023090508443629000_dmad011-B75","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1007\/s00404-019-05251-4","article-title":"Hormone replacement versus natural frozen embryo transfer for euploid embryos","volume":"300","author":"Wang","year":"2019","journal-title":"Arch Gynecol Obstet"},{"key":"2023090508443629000_dmad011-B76","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1093\/humrep\/deaa093","article-title":"Effects of different cycle regimens for frozen embryo transfer on perinatal outcomes of singletons","volume":"35","author":"Wang","year":"2020","journal-title":"Hum Reprod"},{"key":"2023090508443629000_dmad011-B77","doi-asserted-by":"crossref","first-page":"327","DOI":"10.3389\/fmed.2020.00327","article-title":"Pregnancy outcomes after different cycle regimens for frozen-thawed embryo transfer: a retrospective study using propensity score matching","volume":"7","author":"Wang","year":"2020","journal-title":"Front Med (Lausanne)"},{"key":"2023090508443629000_dmad011-B78","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3389\/fmed.2020.00104","article-title":"Increased risk of pre-eclampsia after frozen-thawed embryo transfer in programming cycles","volume":"7","author":"Wang","year":"2020","journal-title":"Front Med (Lausanne)"},{"key":"2023090508443629000_dmad011-B79","doi-asserted-by":"crossref","first-page":"727753","DOI":"10.3389\/fmed.2021.727753","article-title":"Pregnancy outcomes after frozen-thawed embryo transfer in the absence of a corpus luteum","volume":"8","author":"Waschkies","year":"2021","journal-title":"Front Med (Lausanne)"},{"key":"2023090508443629000_dmad011-B80","author":"Weissman"},{"key":"2023090508443629000_dmad011-B81","first-page":"332A","article-title":"The impact of the mode of conception on periconceptional maternal cardiovascular adaptation to pregnancy: the renin-angiotensin-aldosterone-system","volume":"27","author":"Wiegel","year":"2020","journal-title":"Reprod Sci"},{"key":"2023090508443629000_dmad011-B82","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/s12958-022-01009-x","article-title":"The impact of different endometrial preparation protocols on obstetric and neonatal complications in frozen-thawed embryo transfer: a retrospective cohort study of 3,458 singleton deliveries","volume":"20","author":"Xu","year":"2022","journal-title":"Reprod Biol Endocrinol"},{"key":"2023090508443629000_dmad011-B83","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1186\/s12884-022-04682-3","article-title":"Adverse obstetric and perinatal outcomes in 2333 singleton pregnancies conceived after different endometrial preparation protocols: a retrospective study in China","volume":"22","author":"Yang","year":"2022","journal-title":"BMC Pregnancy Childbirth"},{"key":"2023090508443629000_dmad011-B84","first-page":"CD011184","article-title":"Fresh versus frozen embryo transfers in assisted reproduction","volume":"2","author":"Zaat","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"2023090508443629000_dmad011-B85","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.rbmo.2021.01.015","article-title":"Increased obstetric and neonatal risks in artificial cycles for frozen embryo transfers?","volume":"42","author":"Zaat","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"2023090508443629000_dmad011-B86","doi-asserted-by":"crossref","first-page":"hoab035","DOI":"10.1093\/hropen\/hoab035","article-title":"Is home-based monitoring of ovulation to time frozen embryo transfer a cost-effective alternative for hospital-based monitoring of ovulation? Study protocol of the multicentre, non-inferiority Antarctica-2 randomised controlled trial","volume":"2021","author":"Zaat","year":"2021","journal-title":"Hum Reprod Open"},{"key":"2023090508443629000_dmad011-B87","doi-asserted-by":"crossref","first-page":"hoac021","DOI":"10.1093\/hropen\/hoac021","article-title":"Facilitators and barriers for home-based monitoring to time frozen embryo transfers in IVF among women and healthcare providers","volume":"2022","author":"Zaat","year":"2022","journal-title":"Hum Reprod Open"},{"key":"2023090508443629000_dmad011-B88","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0015-0282(16)48029-5","article-title":"Two pregnancies following transfer of intact frozen-thawed embryos","volume":"42","author":"Zeilmaker","year":"1984","journal-title":"Fertil Steril"},{"key":"2023090508443629000_dmad011-B89","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.fertnstert.2021.09.033","article-title":"The impact of different cycle regimens on birthweight of singletons in frozen-thawed embryo transfer cycles of ovulatory women","volume":"117","author":"Zhou","year":"2022","journal-title":"Fertil Steril"},{"key":"2023090508443629000_dmad011-B90","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s12958-020-00601-3","article-title":"Increased risk of maternal and neonatal complications in hormone replacement therapy cycles in frozen embryo transfer","volume":"18","author":"Zong","year":"2020","journal-title":"Reprod Biol Endocrinol"}],"container-title":["Human Reproduction Update"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/humupd\/article-pdf\/29\/5\/634\/51344780\/dmad011.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/humupd\/article-pdf\/29\/5\/634\/51344780\/dmad011.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T04:47:47Z","timestamp":1693889267000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humupd\/article\/29\/5\/634\/7161073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,12]]},"references-count":88,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5,12]]},"published-print":{"date-parts":[[2023,9,5]]}},"URL":"https:\/\/doi.org\/10.1093\/humupd\/dmad011","relation":{},"ISSN":["1355-4786","1460-2369"],"issn-type":[{"value":"1355-4786","type":"print"},{"value":"1460-2369","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,10,1]]},"published":{"date-parts":[[2023,5,12]]}}}