{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:05:34Z","timestamp":1792785934546,"version":"4.5.0"},"reference-count":441,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Melbourne, Faculty of Science and School of BioSciences held by EGB","id":[{"id":"https:\/\/ror.org\/01ej9dk98","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Men attending ART clinics often have poor fertility awareness and are typically overlooked for psychological support. Recent developments in understanding the link between sub-fertility, healthspan and lifespan enforce the need for comprehensive health assessments of men attending ART clinics. Evidence now suggests paternal factors including genetics, epigenetics, paternal age, oxidative stress and DNA damage contribute to embryo development and the health of the offspring. With the described decline in global sperm counts, overall male reproductive health and the increased utilisation of ART, it is imperative that research focuses on improving ART protocols for male factor infertility and investigates novel treatments for patients. Sperm contributions in ART are often overlooked, leading to optimisation of the clinical environment to focus on oocytes and embryos. Research into improving ART protocols for sperm is growing, but the clinical implementation has been slow. In parallel, current treatment options for male infertility are limited to procedures like ICSI, which bypass the underlying physiological causes of infertility. Ongoing research into sperm in clinical settings, as well as better patient psychosocial care, is therefore key to improving patient outcomes and wellbeing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE AND RATIONALE<\/jats:title>\n                    <jats:p>This review aims to evaluate the current standing of male reproductive health management in ART clinics with a unique focus on integrated patient care from men\u2019s fertility awareness, through to psychosocial support and targeted education. Additionally, this review aims to identify major barriers that currently prevent rapid integration of novel technologies for male infertility diagnostics and treatments into ART clinics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SEARCH METHODS<\/jats:title>\n                    <jats:p>PubMed searches were performed to identify peer-reviewed articles and reviews using the following terms: \u2018sperm preparation\/selection\u2019, \u2018male reproductive health\u2019, \u2018male infertility\u2019, \u2018diagnostics\u2019, \u2018cryopreservation\u2019, \u2018ART\u2019, \u2018fertility education\u2019, \u2018fertility awareness\u2019, \u2018artificial intelligence\u2019, and \u2018sperm\u2019 in combination with other key words related to the subject. No restriction was placed on date; all relevant studies up until March\u00a02026 were evaluated and discussed. References within articles were also searched.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OUTCOMES<\/jats:title>\n                    <jats:p>In an ART setting, men rarely receive routine healthcare follow-up after providing a sample for assisted reproduction. Through integration of several underrepresented aspects of male health care, this review concludes that male reproductive health should be managed more collaboratively by medical specialists, including general practitioners, urologists, endocrinologists and andrologists, to understand the underlying cause of male infertility and determine an appropriate treatment. Moreover, this review finds that the integration of mental health professionals into the ART clinic environment is urgently needed to ensure appropriate counselling and care for people during and following fertility treatment. Finally, we determined that a lack of direct collaboration between researchers and clinical practitioners may be partly responsible for the slow uptake of novel technologies into the ART clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>WIDER IMPLICATIONS<\/jats:title>\n                    <jats:p>Further research needs to be undertaken to improve public health messaging and education for men about their fertility. An overarching theme identified by this review is the need for targeted collaboration between research scientists and clinicians to improve men\u2019s reproductive care, in turn, culminating in faster clinical adoption of beneficial techniques and products to improve patient outcomes. This review highlights an urgent need for more integrated models of fertility care that extend from men\u2019s fertility awareness and education, through to improvements of \u2018in clinic\u2019 appraisal of the underlying causes of male infertility, and finally, better inclusion of men\u2019s psychosocial support into reproductive care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>REGISTRATION NUMBER<\/jats:title>\n                    <jats:p>n\/a<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/humupd\/dmag027","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T11:25:44Z","timestamp":1787570744000},"source":"Crossref","is-referenced-by-count":0,"title":["Male infertility research for the ART clinic: priorities to enhance patient outcomes, education and wellbeing"],"prefix":"10.1093","author":[{"given":"Georgia A","family":"Bennett","sequence":"first","affiliation":[{"name":"School of Biosciences, Faculty of Science, Bio21 Institute, The University of Melbourne , Parkville, Victoria,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon P","family":"Smyth","sequence":"additional","affiliation":[{"name":"School of Biosciences, Faculty of Science, Bio21 Institute, The University of Melbourne , Parkville, Victoria,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3138-8274","authenticated-orcid":false,"given":"David K","family":"Gardner","sequence":"additional","affiliation":[{"name":"School of Biosciences, Faculty of Science, Bio21 Institute, The University of Melbourne , Parkville, Victoria,","place":["Australia"]},{"name":"Melbourne IVF , Collingwood, Victoria,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7256-1403","authenticated-orcid":false,"given":"Elizabeth G","family":"Bromfield","sequence":"additional","affiliation":[{"name":"School of Biosciences, Faculty of Science, Bio21 Institute, The University of Melbourne , Parkville, Victoria,","place":["Australia"]},{"name":"Reproductive and Family Health Research Program, Hunter Medical Research Institute , New Lambton Heights, New South Wales,","place":["Australia"]},{"name":"Centre for Reproductive Science, School of Science, College of Engineering, Science and Environment, University of Newcastle , Callaghan, New South Wales,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"key":"2026092423210397400_dmag027-B1","doi-asserted-by":"crossref","first-page":"104121","DOI":"10.1016\/j.compbiomed.2020.104121","article-title":"Effect of deep transfer and multi-task learning on sperm abnormality detection","volume":"128","author":"Abbasi","year":"2021","journal-title":"Comput Biol Med"},{"key":"2026092423210397400_dmag027-B2","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/humupd\/dmn061","article-title":"Techniques for cryopreservation of individual or small numbers of human spermatozoa: a systematic review","volume":"15","author":"AbdelHafez","year":"2009","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B3","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s10561-019-09801-7","article-title":"Does Myoinositol supplement improve sperm parameters and DNA integrity in patients with oligoasthenoteratozoospermia after the freezing-thawing process?","volume":"21","author":"Abdolsamadi","year":"2020","journal-title":"Cell Tissue Bank"},{"key":"2026092423210397400_dmag027-B4","doi-asserted-by":"crossref","first-page":"e12959","DOI":"10.1111\/and.12959","article-title":"Effect of in vitro vitamin E (alpha-tocopherol) supplementation in human spermatozoon submitted to oxidative stress","volume":"50","author":"Adami","year":"2018","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B5","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.fertnstert.2025.02.009","article-title":"How many infants have been born with the help of assisted reproductive technology?","volume":"124","author":"Adamson","year":"2025","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B6","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s12958-015-0032-1","article-title":"A unique view on male infertility around the globe","volume":"13","author":"Agarwal","year":"2015","journal-title":"Reprod Biol Endocrinol"},{"key":"2026092423210397400_dmag027-B7","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.rbmo.2013.11.015","article-title":"Vitrification is not superior to rapid freezing of normozoospermic spermatozoa: effects on sperm parameters, DNA fragmentation and hyaluronan binding","volume":"28","author":"Agha-Rahimi","year":"2014","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B8","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.fertnstert.2010.06.011","article-title":"Psychosocial support for infertile couples during assisted reproductive technology treatment","volume":"95","author":"Agostini","year":"2011","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B9","doi-asserted-by":"crossref","first-page":"e12773","DOI":"10.1111\/and.12773","article-title":"Ascorbic acid reduces redox potential in human spermatozoa subjected to heat-induced oxidative stress","volume":"49","author":"Ahmad","year":"2017","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B10","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1093\/humrep\/dei024","article-title":"Development of a novel electrophoretic system for the isolation of human spermatozoa","volume":"20","author":"Ainsworth","year":"2005","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B11","doi-asserted-by":"crossref","first-page":"2645","DOI":"10.1093\/humrep\/deae230","article-title":"Paternal age, de novo mutations, and offspring health? New directions for an ageing problem","volume":"39","author":"Aitken","year":"2024","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1071\/RD15325","article-title":"Causes and consequences of oxidative stress in spermatozoa","volume":"28","author":"Aitken","year":"2016","journal-title":"Reprod Fertil Dev"},{"key":"2026092423210397400_dmag027-B13","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1095\/biolreprod.112.102020","article-title":"Sperm motility is lost in vitro as a consequence of mitochondrial free radical production and the generation of electrophilic aldehydes but can be significantly rescued by the presence of nucleophilic thiols","volume":"87","author":"Aitken","year":"2012","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B14","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4103\/1008-682X.122203","article-title":"Oxidative stress and male reproductive health","volume":"16","author":"Aitken","year":"2014","journal-title":"Asian J Androl"},{"key":"2026092423210397400_dmag027-B15","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1093\/humrep\/dex281","article-title":"New permeable cryoprotectant-free vitrification method for native human sperm","volume":"32","author":"Aizpurua","year":"2017","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B16","doi-asserted-by":"crossref","first-page":"e13672","DOI":"10.1111\/and.13672","article-title":"The physiology of male reproduction: impact of drugs and their abuse on male fertility","volume":"52","author":"Ajayi","year":"2020","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B17","doi-asserted-by":"crossref","first-page":"e12703","DOI":"10.1111\/and.12703","article-title":"Total antioxidant status and lipid peroxidation with and without in vitro zinc supplementation in infertile men","volume":"49","author":"Ajina","year":"2017","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B18","first-page":"633","article-title":"Slow cryopreservation is not superior to vitrification in human spermatozoa; an experimental controlled study","volume":"13","author":"Ali Mohamed","year":"2015","journal-title":"Iran J Reprod Med"},{"key":"2026092423210397400_dmag027-B19","doi-asserted-by":"crossref","first-page":"e12845","DOI":"10.1111\/and.12845","article-title":"Comparison and evaluation of capacitation and acrosomal reaction in freeze-thawed human ejaculated spermatozoa treated with L-carnitine and pentoxifylline","volume":"50","author":"Aliabadi","year":"2018","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B20","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1093\/humupd\/dmt046","article-title":"The combined human sperm proteome: cellular pathways and implications for basic and clinical science","volume":"20","author":"Amaral","year":"2014","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B21","doi-asserted-by":"crossref","first-page":"5670","DOI":"10.1021\/pr500652y","article-title":"Identification of proteins involved in human sperm motility using high-throughput differential proteomics","volume":"13","author":"Amaral","year":"2014","journal-title":"J Proteome Res"},{"key":"2026092423210397400_dmag027-B22","doi-asserted-by":"crossref","first-page":"3200","DOI":"10.3390\/ph3103200","article-title":"Endocannabinoids and human sperm cells","volume":"3","author":"Ambrosini","year":"2010","journal-title":"Pharmaceuticals (Basel)"},{"key":"2026092423210397400_dmag027-B23","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1095\/biolreprod.105.046060","article-title":"Oleoylethanolamide protects human sperm cells from oxidation stress: studies on cases of idiopathic infertility","volume":"74","author":"Ambrosini","year":"2006","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B24","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.fertnstert.2014.07.767","article-title":"Relationship between seminal plasma levels of anandamide congeners palmitoylethanolamide and oleoylethanolamide and semen quality","volume":"102","author":"Amoako","year":"2014","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B25","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1038\/s41467-025-56193-2","article-title":"Specific types of male infertility are correlated with T cell exhaustion or senescence signatures","volume":"16","author":"Amodio","year":"2025","journal-title":"Nat Commun"},{"key":"2026092423210397400_dmag027-B26","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1093\/oxfordjournals.humrep.a135883","article-title":"Improvement of sperm motility by the addition of progesterone to the Percoll medium during sperm purification","volume":"10","author":"Andersen","year":"1995","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B27","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1530\/RAF-20-0041","article-title":"Is pre-freeze sperm preparation more advantageous than post-freeze?","volume":"2","author":"Androni","year":"2021","journal-title":"Reprod Fertil"},{"key":"2026092423210397400_dmag027-B28","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S1472-6483(10)60150-2","article-title":"Intracytoplasmic morphologically selected sperm injection: a prospective randomized trial","volume":"16","author":"Antinori","year":"2008","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B29","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.fertnstert.2015.06.043","article-title":"Single human sperm cryopreservation method using hollow-core agarose capsules","volume":"104","author":"Araki","year":"2015","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B30","first-page":"71","article-title":"Effects of pentoxifylline on sperm motility characteristics and motility longevity of postthaw cryopreserved semen using computer-assisted semen analysis (CASA)","volume":"77","author":"Aribarg","year":"1994","journal-title":"J Med Assoc Thai"},{"key":"2026092423210397400_dmag027-B31","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/09513590.2016.1254179","article-title":"In vitro effect of Myo-inositol on sperm motility in normal and oligoasthenospermia patients undergoing in vitro fertilization","volume":"33","author":"Artini","year":"2017","journal-title":"Gynecol Endocrinol"},{"key":"2026092423210397400_dmag027-B32","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1042\/bj2560251","article-title":"The antioxidant action of taurine, hypotaurine and their metabolic precursors","volume":"256","author":"Aruoma","year":"1988","journal-title":"Biochem J"},{"key":"2026092423210397400_dmag027-B33","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.cryobiol.2020.07.001","article-title":"Supplementation of freezing media with alpha lipoic acid preserves the structural and functional characteristics of sperm against cryodamage in infertile men with asthenoteratozoospermia","volume":"96","author":"Asa","year":"2020","journal-title":"Cryobiology"},{"key":"2026092423210397400_dmag027-B34","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1002\/adhm.201400058","article-title":"Selection of functional human sperm with higher DNA integrity and fewer reactive oxygen species","volume":"3","author":"Asghar","year":"2014","journal-title":"Adv Healthc Mater"},{"key":"2026092423210397400_dmag027-B35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3109\/01485019408987797","article-title":"Effect of natural antioxidants tocopherol and ascorbic acids in maintenance of sperm activity during freeze-thaw process","volume":"33","author":"Askari","year":"1994","journal-title":"Arch Androl"},{"key":"2026092423210397400_dmag027-B36","doi-asserted-by":"crossref","first-page":"e14528","DOI":"10.1111\/and.14528","article-title":"Effect of Myo-inositol on sperm quality and biochemical factors in cryopreserved semen of patients with Asthenospermia","volume":"54","author":"Azizi","year":"2022","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B37","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1016\/j.bpj.2017.03.037","article-title":"Antioxidant and membrane binding properties of serotonin protect lipids from oxidation","volume":"112","author":"Azouzi","year":"2017","journal-title":"Biophys J"},{"key":"2026092423210397400_dmag027-B38","doi-asserted-by":"crossref","first-page":"167","DOI":"10.32725\/jab.2019.015","article-title":"Prediction of semen quality using artificial neural network","volume":"17","author":"Badura","year":"2019","journal-title":"J Appl Biomed"},{"key":"2026092423210397400_dmag027-B39","doi-asserted-by":"crossref","first-page":"3566","DOI":"10.3390\/cells10123566","article-title":"Sperm selection for ICSI: do we have a winner?","volume":"10","author":"Baldini","year":"2021","journal-title":"Cells"},{"key":"2026092423210397400_dmag027-B40","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.fertnstert.2003.06.011","article-title":"Impact of repeated antral follicle counts on the prediction of poor ovarian response in women undergoing in vitro fertilization","volume":"81","author":"Bancsi","year":"2004","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B41","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/and.12130","article-title":"Cryoprotective effect of L-carnitine on motility, vitality and DNA oxidation of human spermatozoa","volume":"46","author":"Banihani","year":"2014","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B42","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1439-0272.2011.01216.x","article-title":"Human sperm DNA oxidation, motility and viability in the presence of L-carnitine during in vitro incubation and centrifugation","volume":"44","author":"Banihani","year":"2012","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B43","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.fertnstert.2021.03.039","article-title":"International Committee for Monitoring Assisted Reproductive Technologies (ICMART): world report on assisted reproductive technologies, 2013","volume":"116","author":"Banker","year":"2021","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B44","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.urology.2014.04.043","article-title":"Functional sperm testing and the role of proteomics in the evaluation of male infertility","volume":"84","author":"Barazani","year":"2014","journal-title":"Urology"},{"key":"2026092423210397400_dmag027-B45","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1093\/humrep\/der312","article-title":"ESHRE special interest group for andrology basic semen analysis course: a continued focus on accuracy, quality, efficiency and clinical relevance","volume":"26","author":"Barratt","year":"2011","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B46","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1093\/humupd\/dmx021","article-title":"The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance-challenges and future research opportunities","volume":"23","author":"Barratt","year":"2017","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B47","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/humrep\/dey019","article-title":"The significance of human spermatozoa vacuoles can be elucidated by a novel procedure of array comparative genomic hybridization","volume":"33","author":"Berkovitz","year":"2018","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B48","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1093\/humrep\/dey304","article-title":"A novel solution for freezing small numbers of spermatozoa using a sperm vitrification device","volume":"33","author":"Berkovitz","year":"2018","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B49","doi-asserted-by":"crossref","first-page":"e0262661","DOI":"10.1371\/journal.pone.0262661","article-title":"Robust and generalizable embryo selection based on artificial intelligence and time-lapse image sequences","volume":"17","author":"Berntsen","year":"2022","journal-title":"PLoS One"},{"key":"2026092423210397400_dmag027-B50","doi-asserted-by":"crossref","first-page":"hoab027","DOI":"10.1093\/hropen\/hoab027","article-title":"How do young men want to receive information about fertility? Young men\u2019s attitudes towards a fertility campaign targeting men in Copenhagen, Denmark","volume":"2021","author":"Berthelsen","year":"2021","journal-title":"Hum Reprod Open"},{"key":"2026092423210397400_dmag027-B51","doi-asserted-by":"crossref","first-page":"10","DOI":"10.4103\/aja202334","article-title":"Psychological consequences of a diagnosis of infertility in men: a systematic analysis","volume":"26","author":"Biggs","year":"2024","journal-title":"Asian J Androl"},{"key":"2026092423210397400_dmag027-B52","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nrurol.2017.69","article-title":"Oxidative stress and male infertility","volume":"14","author":"Bisht","year":"2017","journal-title":"Nat Rev Urol"},{"key":"2026092423210397400_dmag027-B53","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1016\/S0021-9258(19)40024-0","article-title":"Progesterone and 17 alpha-hydroxyprogesterone. Novel stimulators of calcium influx in human sperm","volume":"265","author":"Blackmore","year":"1990","journal-title":"J Biol Chem"},{"key":"2026092423210397400_dmag027-B54","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.rbmo.2013.09.019","article-title":"High-magnification selection of spermatozoa prior to oocyte injection: confirmed and potential indications","volume":"28","author":"Boitrelle","year":"2014","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B55","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.1093\/humrep\/13.11.3262","article-title":"Psychological reactions during in-vitro fertilization: similar response pattern in husbands and wives","volume":"13","author":"Boivin","year":"1998","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B56","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1093\/humrep\/dey107","article-title":"An experimental evaluation of the benefits and costs of providing fertility information to adolescents and emerging adults","volume":"33","author":"Boivin","year":"2018","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B57","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1093\/humupd\/dmw036","article-title":"The epidemiologic evidence linking prenatal and postnatal exposure to endocrine disrupting chemicals with male reproductive disorders: a systematic review and meta-analysis","volume":"23","author":"Bonde","year":"2016","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B58","doi-asserted-by":"crossref","first-page":"e13818","DOI":"10.1111\/and.13818","article-title":"Supplementing post-wash asthenozoospermic human spermatozoa with coenzyme Q10 for 1 hr in vitro improves sperm motility, but not oxidative stress","volume":"52","author":"Boonsimma","year":"2020","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B59","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0303-7207(00)00347-6","article-title":"Reezing a few testicular spermatozoa retrieved by TESA","volume":"169","author":"Borini","year":"2000","journal-title":"Mol Cell Endocrinol"},{"key":"2026092423210397400_dmag027-B60","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.cryobiol.2009.10.012","article-title":"Resveratrol and ascorbic acid prevent DNA damage induced by cryopreservation in human semen","volume":"60","author":"Branco","year":"2010","journal-title":"Cryobiology"},{"key":"2026092423210397400_dmag027-B61","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1093\/humrep\/dep340","article-title":"When and why do subfertile couples discontinue their fertility care? A longitudinal cohort study in a secondary care subfertility population","volume":"24","author":"Brandes","year":"2009","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B62","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1093\/oxfordjournals.humrep.a136291","article-title":"Pentoxifylline-supplemented cryoprotectant improves human sperm motility after cryopreservation","volume":"10","author":"Brennan","year":"1995","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B63","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.1093\/humrep\/dev214","article-title":"The impact of oxidative stress on chaperone-mediated human sperm-egg interaction","volume":"30","author":"Bromfield","year":"2015","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B64","first-page":"91","article-title":"Proteolytic degradation of heat shock protein A2 occurs in response to oxidative stress in male germ cells of the mouse","volume":"23","author":"Bromfield","year":"2017","journal-title":"Mol Hum Reprod"},{"key":"2026092423210397400_dmag027-B65","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1093\/humrep\/des402","article-title":"Fertility knowledge and beliefs about fertility treatment: findings from the International Fertility Decision-making Study","volume":"28","author":"Bunting","year":"2013","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B66","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/s41585-022-00640-y","article-title":"Male infertility and somatic health - insights into lipid damage as a mechanistic link","volume":"19","author":"Burke","year":"2022","journal-title":"Nat Rev Urol"},{"key":"2026092423210397400_dmag027-B67","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1093\/humrep\/15.suppl_1.28","article-title":"Effects of progesterone on sperm function: mechanisms of action","volume":"15","author":"Calogero","year":"2000","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B68","doi-asserted-by":"crossref","first-page":"101273","DOI":"10.1016\/j.mam.2024.101273","article-title":"Obesity and male fertility disorders","volume":"97","author":"Cannarella","year":"2024","journal-title":"Mol Aspects Med"},{"key":"2026092423210397400_dmag027-B69","doi-asserted-by":"crossref","first-page":"103252","DOI":"10.1016\/j.rbmo.2023.06.007","article-title":"Cryostorage management of reproductive cells and tissues in ART: status, needs, opportunities and potential new challenges","volume":"47","author":"Canosa","year":"2023","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B70","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1136\/bmj.305.6854.609","article-title":"Evidence for decreasing quality of semen during past 50 years","volume":"305","author":"Carlsen","year":"1992","journal-title":"BMJ"},{"key":"2026092423210397400_dmag027-B71","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1007\/s10815-017-0955-x","article-title":"Selecting embryos with the highest implantation potential using data mining and decision tree based on classical embryo morphology and morphokinetics","volume":"34","author":"Carrasco","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B72","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1111\/andr.13356","article-title":"MiOXSYS((R)) and OxiSperm((R)) II assays appear to provide no clinical utility for determining oxidative stress in human sperm-results from repeated semen collections","volume":"11","author":"Castleton","year":"2023","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B73","doi-asserted-by":"crossref","first-page":"897101","DOI":"10.3389\/fendo.2022.897101","article-title":"Advanced paternal age and future generations","volume":"13","author":"Chan","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2026092423210397400_dmag027-B74","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.21037\/tau-24-195","article-title":"A narrative review of sperm selection technology for assisted reproduction techniques","volume":"13","author":"Charles","year":"2024","journal-title":"Transl Androl Urol"},{"key":"2026092423210397400_dmag027-B75","first-page":"330","article-title":"The effect of L-carnitine and coenzyme Q10 on the sperm motility, DNA fragmentation, chromatin structure and oxygen free radicals during, before and after freezing in oligospermia men","volume":"18","author":"Chavoshi Nezhad","year":"2021","journal-title":"Urol J"},{"key":"2026092423210397400_dmag027-B76","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s00404-013-2801-4","article-title":"Influence of reactive oxygen species on human sperm functions and fertilizing capacity including therapeutical approaches","volume":"288","author":"Chen","year":"2013","journal-title":"Arch Gynecol Obstet"},{"key":"2026092423210397400_dmag027-B77","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1093\/humrep\/den060","article-title":"Protective effect of antioxidant supplementation in sperm-preparation medium against oxidative stress in human spermatozoa","volume":"23","author":"Chi","year":"2008","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B78","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/j.1939-4640.2000.tb03275.x","article-title":"Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men","volume":"21","author":"Chia","year":"2000","journal-title":"J Androl"},{"key":"2026092423210397400_dmag027-B79","doi-asserted-by":"crossref","first-page":"e0165125","DOI":"10.1371\/journal.pone.0165125","article-title":"Measuring sperm DNA fragmentation and clinical outcomes of medically assisted reproduction: a systematic review and meta-analysis","volume":"11","author":"Cissen","year":"2016","journal-title":"PLoS One"},{"key":"2026092423210397400_dmag027-B80","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/and.12434","article-title":"Reliable single sperm cryopreservation in cell sleepers for azoospermia management","volume":"48","author":"Coetzee","year":"2016","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B81","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1093\/humrep\/12.5.994","article-title":"Cryopreservation of single human spermatozoa","volume":"12","author":"Cohen","year":"1997","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B82","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3164\/jcbn.08-251","article-title":"Ascorbic Acid in human seminal plasma: determination and its relationship to sperm quality","volume":"45","author":"Colagar","year":"2009","journal-title":"J Clin Biochem Nutr"},{"key":"2026092423210397400_dmag027-B83","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.fertnstert.2007.04.055","article-title":"Do sperm DNA integrity tests predict pregnancy with in vitro fertilization?","volume":"89","author":"Collins","year":"2008","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B84","first-page":"891","article-title":"Inositol activity in oligoasthenoteratospermia\u2014an in vitro study","volume":"14","author":"Colone","year":"2010","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"2026092423210397400_dmag027-B85","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/j.urology.2012.03.005","article-title":"Myoinositol: does it improve sperm mitochondrial function and sperm motility?","volume":"79","author":"Condorelli","year":"2012","journal-title":"Urology"},{"key":"2026092423210397400_dmag027-B86","first-page":"129","article-title":"Effects of Myoinositol on sperm mitochondrial function in-vitro","volume":"15","author":"Condorelli","year":"2011","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"2026092423210397400_dmag027-B87","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.rbmo.2019.10.003","article-title":"There is only one thing that is truly important in an IVF laboratory: everything\u2019 Cairo Consensus Guidelines on IVF Culture Conditions","volume":"40","author":"Consensus Group","year":"2020","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B88","doi-asserted-by":"crossref","first-page":"525","DOI":"10.7754\/Clin.Lab.2014.141005","article-title":"Diagnostic accuracies of the TUNEL, SCD, and comet based sperm DNA fragmentation assays for male infertility: a meta-analysis study","volume":"61","author":"Cui","year":"2015","journal-title":"Clin Lab"},{"key":"2026092423210397400_dmag027-B89","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.fertnstert.2020.09.159","article-title":"Evaluating predictive models in reproductive medicine","volume":"114","author":"Curchoe","year":"2020","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B90","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1038\/s41585-025-01123-6","article-title":"Sperm DNA fragmentation and its influence on mammalian reproduction","volume":"23","author":"Dabiri","year":"2026","journal-title":"Nat Rev Urol"},{"key":"2026092423210397400_dmag027-B91","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/humrep\/deu328","article-title":"Fertility awareness online: the efficacy of a fertility education website in increasing knowledge and changing fertility beliefs","volume":"30","author":"Daniluk","year":"2015","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B92","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1093\/humrep\/dew265","article-title":"Men\u2019s knowledge of their own fertility: a population-based survey examining the awareness of factors that are associated with male infertility","volume":"31","author":"Daumler","year":"2016","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B93","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.fertnstert.2011.12.045","article-title":"Semen analysis: looking for an upgrade in class","volume":"97","author":"De Jonge","year":"2012","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B94","first-page":"CD007411","article-title":"Antioxidants for male subfertility","volume":"5","author":"de Ligny","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"key":"2026092423210397400_dmag027-B95","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.3390\/antiox10081283","article-title":"Oxidative stress and male fertility: role of antioxidants and inositols","volume":"10","author":"De Luca","year":"2021","journal-title":"Antioxidants (Basel)"},{"key":"2026092423210397400_dmag027-B96","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/biolre\/ioaa173","article-title":"Hyaluronidase-based swim-up for semen selection in patients with human papillomavirus semen infection","volume":"104","author":"De Toni","year":"2021","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B97","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1016\/j.fertnstert.2013.08.005","article-title":"Semen cryopreservation for men banking for oligospermia, cancers, and other pathologies: prediction of post-thaw outcome using basal semen quality","volume":"100","author":"Degl\u2019Innocenti","year":"2013","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B98","doi-asserted-by":"crossref","first-page":"e14409","DOI":"10.1111\/and.14409","article-title":"The association of impaired semen quality and pregnancy rates in assisted reproduction technology cycles: systematic review and meta-analysis","volume":"54","author":"Del Giudice","year":"2022","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B99","doi-asserted-by":"crossref","first-page":"e13263","DOI":"10.1111\/and.13263","article-title":"Sperm DNA fragmentation index influences assisted reproductive technology outcome: a systematic review and meta-analysis combined with a retrospective cohort study","volume":"51","author":"Deng","year":"2019","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B100","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.freeradbiomed.2017.10.342","article-title":"Melatonin reduces oxidative damage and upregulates heat shock protein 90 expression in cryopreserved human semen","volume":"113","author":"Deng","year":"2017","journal-title":"Free Radic Biol Med"},{"key":"2026092423210397400_dmag027-B101","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S1472-6483(10)62109-8","article-title":"Single sperm cryopreservation on cryoloops: an alternative to hamster zona for freezing individual spermatozoa","volume":"9","author":"Desai","year":"2004","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B102","doi-asserted-by":"crossref","first-page":"854837","DOI":"10.1155\/2012\/854837","article-title":"Human sperm cryopreservation: update on techniques, effect on DNA integrity, and implications for ART","volume":"2012","author":"Di Santo","year":"2012","journal-title":"Adv Urol"},{"key":"2026092423210397400_dmag027-B103","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1210\/er.2009-0002","article-title":"Endocrine-disrupting chemicals: an Endocrine Society scientific statement","volume":"30","author":"Diamanti-Kandarakis","year":"2009","journal-title":"Endocr Rev"},{"key":"2026092423210397400_dmag027-B104","doi-asserted-by":"crossref","first-page":"635","DOI":"10.4103\/aja202425","article-title":"Assessing the efficacy of a novel sperm-washing medium enriched with serotonin, L-carnitine, and coenzyme Q10: an observational cohort study","volume":"26","author":"Dogan","year":"2024","journal-title":"Asian J Androl"},{"key":"2026092423210397400_dmag027-B105","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/S0015-0282(99)00267-8","article-title":"Antioxidant supplementation in vitro does not improve human sperm motility","volume":"72","author":"Donnelly","year":"1999","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B106","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/mutage\/15.1.61","article-title":"Glutathione and hypotaurine in vitro: effects on human sperm motility, DNA integrity and production of reactive oxygen species","volume":"15","author":"Donnelly","year":"2000","journal-title":"Mutagenesis"},{"key":"2026092423210397400_dmag027-B107","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/S0015-0282(01)02834-5","article-title":"Cryopreservation of human semen and prepared sperm: effects on motility parameters and DNA integrity","volume":"76","author":"Donnelly","year":"2001","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B108","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/humupd\/dmaa010","article-title":"Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis","volume":"26","author":"Du Fosse","year":"2020","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B109","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1439-0272.2009.00964.x","article-title":"The in vitro effects of melatonin on human sperm function and its scavenging activities on NO and ROS","volume":"42","author":"Du Plessis","year":"2010","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B110","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1093\/humrep\/deaa242","article-title":"Top 10 priorities for future infertility research: an international consensus development studydagger double dagger","volume":"35","author":"Duffy","year":"2020","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B111","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.fertnstert.2025.06.003","article-title":"International Committee for Monitoring Assisted Reproductive Technologies world report: assisted reproductive technology, 2019","volume":"124","author":"Dyer","year":"2025","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B112","first-page":"100336","article-title":"Leptin and prolactin reduce cryodamage in normozoospermic human semen samples during cryopreservation","volume":"21","author":"Ebrahimi","year":"2023","journal-title":"Rev Int Androl"},{"key":"2026092423210397400_dmag027-B113","doi-asserted-by":"crossref","first-page":"102343","DOI":"10.1016\/j.eclinm.2023.102343","article-title":"The current status of IVF: are we putting the needs of the individual first?","volume":"65","author":"eClinicalMedicine","year":"2023","journal-title":"EClinicalMedicine"},{"key":"2026092423210397400_dmag027-B114","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.fertnstert.2014.10.017","article-title":"Relationship between semen production and medical comorbidity","volume":"103","author":"Eisenberg","year":"2015","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B115","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.fertnstert.2012.07.1128","article-title":"Successful delivery derived from vitrified-warmed spermatozoa from a patient with nonobstructive azoospermia","volume":"98","author":"Endo","year":"2012","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B116","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.rbmo.2011.11.016","article-title":"Simple vitrification for small numbers of human spermatozoa","volume":"24","author":"Endo","year":"2012","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B117","doi-asserted-by":"crossref","first-page":"36262","DOI":"10.1074\/jbc.M203883200","article-title":"Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition","volume":"277","author":"Enomoto","year":"2002","journal-title":"J Biol Chem"},{"key":"2026092423210397400_dmag027-B118","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1093\/humrep\/dew016","article-title":"Revised guidelines for good practice in IVF laboratories (2015)","volume":"31","author":"ESHRE Guideline Group on Good Practice in IVF Labs","year":"2016","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B119","doi-asserted-by":"crossref","first-page":"3384","DOI":"10.1093\/humrep\/13.12.3384","article-title":"Cryopreservation of human spermatozoa with pentoxifylline improves the post-thaw agonist-induced acrosome reaction rate","volume":"13","author":"Esteves","year":"1998","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B120","doi-asserted-by":"crossref","first-page":"e13874","DOI":"10.1111\/and.13874","article-title":"Sperm DNA fragmentation testing: summary evidence and clinical practice recommendations","volume":"53","author":"Esteves","year":"2021","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B121","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/S1472-6483(10)62000-7","article-title":"Meta-analysis of sperm DNA fragmentation using the sperm chromatin structure assay","volume":"12","author":"Evenson","year":"2006","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B122","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.anireprosci.2016.01.017","article-title":"The Sperm Chromatin Structure Assay (SCSA((R))) and other sperm DNA fragmentation tests for evaluation of sperm nuclear DNA integrity as related to fertility","volume":"169","author":"Evenson","year":"2016","journal-title":"Anim Reprod Sci"},{"key":"2026092423210397400_dmag027-B123","doi-asserted-by":"crossref","first-page":"206","DOI":"10.5935\/1518-0557.20160040","article-title":"Comparison of two sperm processing techniques for low complexity assisted fertilization: sperm washing followed by swim-up and discontinuous density gradient centrifugation","volume":"20","author":"Facio","year":"2016","journal-title":"JBRA Assist Reprod"},{"key":"2026092423210397400_dmag027-B124","doi-asserted-by":"crossref","first-page":"100601","DOI":"10.1016\/j.repbio.2021.100601","article-title":"d-aspartate and N-methyl-d-aspartate promote proliferative activity in mouse spermatocyte GC-2 cells","volume":"22","author":"Falvo","year":"2022","journal-title":"Reprod Biol"},{"key":"2026092423210397400_dmag027-B125","first-page":"103","article-title":"Effects of ascorbic acid on sperm motility, viability, acrosome reaction and DNA integrity in teratozoospermic samples","volume":"12","author":"Fanaei","year":"2014","journal-title":"Iran J Reprod Med"},{"key":"2026092423210397400_dmag027-B126","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.euf.2019.08.001","article-title":"Sperm count and hypogonadism as markers of general male health","volume":"7","author":"Ferlin","year":"2021","journal-title":"Eur Urol Focus"},{"key":"2026092423210397400_dmag027-B127","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1095\/biolreprod.107.065623","article-title":"Long-term effects of mouse intracytoplasmic sperm injection with DNA-fragmented sperm on health and behavior of adult offspring","volume":"78","author":"Fernandez-Gonzalez","year":"2008","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B128","doi-asserted-by":"crossref","first-page":"4934","DOI":"10.1038\/s41467-018-07119-8","article-title":"An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming","volume":"9","author":"Ferraz","year":"2018","journal-title":"Nat Commun"},{"key":"2026092423210397400_dmag027-B129","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/j.2047-2927.2012.00042.x","article-title":"High variability in results of semen analysis in andrology laboratories in Tuscany (Italy): the experience of an external quality control (EQC) programme","volume":"1","author":"Filimberti","year":"2013","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B130","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.21037\/tau-21-276","article-title":"The validity and reliability of computer-aided semen analyzers in performing semen analysis: a systematic review","volume":"10","author":"Finelli","year":"2021","journal-title":"Transl Androl Urol"},{"key":"2026092423210397400_dmag027-B131","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/andr.284","article-title":"HPV-DNA sperm infection and infertility: from a systematic literature review to a possible clinical management proposal","volume":"3","author":"Foresta","year":"2015","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B132","first-page":"523","article-title":"[The redox system in human semen and peroxidative damage of spermatozoa]","volume":"59","author":"Fraczek","year":"2005","journal-title":"Postepy Hig Med Dosw (Online)"},{"key":"2026092423210397400_dmag027-B133","doi-asserted-by":"crossref","first-page":"11003","DOI":"10.1073\/pnas.88.24.11003","article-title":"Ascorbic acid protects against endogenous oxidative DNA damage in human sperm","volume":"88","author":"Fraga","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026092423210397400_dmag027-B134","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.fertnstert.2007.06.009","article-title":"Male age negatively impacts embryo development and reproductive outcome in donor oocyte assisted reproductive technology cycles","volume":"90","author":"Frattarelli","year":"2008","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B135","doi-asserted-by":"crossref","first-page":"e942946","DOI":"10.12659\/MSM.942946","article-title":"Enhancement of frozen-thawed human sperm quality with zinc as a cryoprotective additive","volume":"30","author":"Fu","year":"2024","journal-title":"Med Sci Monit"},{"key":"2026092423210397400_dmag027-B136","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.cryobiol.2010.12.001","article-title":"Reduced glutathione content in human sperm is decreased after cryopreservation: effect of the addition of reduced glutathione to the freezing and thawing extenders","volume":"62","author":"Gadea","year":"2011","journal-title":"Cryobiology"},{"key":"2026092423210397400_dmag027-B137","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.1093\/humrep\/dev177","article-title":"ESHRE guideline: routine psychosocial care in infertility and medically assisted reproduction-a guide for fertility staff","volume":"30","author":"Gameiro","year":"2015","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B138","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1093\/humupd\/dmx001","article-title":"Long-term adjustment to unmet parenthood goals following ART: a systematic review and meta-analysis","volume":"23","author":"Gameiro","year":"2017","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B139","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.fertnstert.2015.09.018","article-title":"Spontaneous fertility and in vitro fertilization outcome: new evidence of human papillomavirus sperm infection","volume":"105","author":"Garolla","year":"2016","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B140","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1093\/humrep\/des009","article-title":"Human papillomavirus sperm infection and assisted reproduction: a dangerous hazard with a possible safe solution","volume":"27","author":"Garolla","year":"2012","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B141","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jri.2013.03.004","article-title":"Sperm viral infection and male infertility: focus on HBV, HCV, HIV, HPV, HSV, HCMV, and AAV","volume":"100","author":"Garolla","year":"2013","journal-title":"J Reprod Immunol"},{"key":"2026092423210397400_dmag027-B142","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1439-0272.1998.tb01177.x","article-title":"In vitro effect of zinc on oxidative changes in human semen","volume":"30","author":"Gavella","year":"1998","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B143","doi-asserted-by":"crossref","first-page":"e13891","DOI":"10.1111\/and.13891","article-title":"The effect of vitamin E on sperm motility and viability in asthenoteratozoospermic men: in vitro study","volume":"53","author":"Ghafarizadeh","year":"2021","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B144","doi-asserted-by":"crossref","first-page":"e12869","DOI":"10.1111\/and.12869","article-title":"Effect of in vitro selenium supplementation on sperm quality in asthenoteratozoospermic men","volume":"50","author":"Ghafarizadeh","year":"2018","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B145","doi-asserted-by":"crossref","first-page":"316","DOI":"10.5653\/cerm.2021.04560","article-title":"The antioxidant roles of L-carnitine and N-acetyl cysteine against oxidative stress on human sperm functional parameters during vitrification","volume":"48","author":"Ghorbani","year":"2021","journal-title":"Clin Exp Reprod Med"},{"key":"2026092423210397400_dmag027-B146","first-page":"34","article-title":"Protective effects of glutathione supplementation against oxidative stress during cryopreservation of human spermatozoa","volume":"37","author":"Ghorbani","year":"2016","journal-title":"Cryo Letters"},{"key":"2026092423210397400_dmag027-B147","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1007\/s12020-016-1013-7","article-title":"In vitro effects of zinc, D-aspartic acid, and coenzyme-Q10 on sperm function","volume":"56","author":"Giacone","year":"2017","journal-title":"Endocrine"},{"key":"2026092423210397400_dmag027-B148","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.fertnstert.2012.02.014","article-title":"DNA integrity is maintained after freeze-drying of human spermatozoa","volume":"97","author":"Gianaroli","year":"2012","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B149","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s10815-013-9962-8","article-title":"Sperm selection using magnetic activated cell sorting (MACS) in assisted reproduction: a systematic review and meta-analysis","volume":"30","author":"Gil","year":"2013","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B150","first-page":"430","article-title":"Sperm selection by magnetic-activated cell sorting before microinjection of autologous oocytes increases cumulative live birth rates with limited clinical impact: a retrospective study in unselected males","volume":"10","author":"Gil Julia","year":"2021","journal-title":"Biology (Basel)"},{"key":"2026092423210397400_dmag027-B151","doi-asserted-by":"crossref","first-page":"103172","DOI":"10.1016\/j.rbmo.2023.01.022","article-title":"Semen processing using magnetic-activated cell sorting before ICSI is deemed safe for obstetric and perinatal outcomes: a retrospective multicentre study","volume":"47","author":"Gil Julia","year":"2023","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B152","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1095\/biolreprod.112.104653","article-title":"Semen parameters can be predicted from environmental factors and lifestyle using artificial intelligence methods","volume":"88","author":"Girela","year":"2013","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B153","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1177\/1352458517734069","article-title":"Male factor infertility and risk of multiple sclerosis: a register-based cohort study","volume":"24","author":"Glazer","year":"2018","journal-title":"Mult Scler"},{"key":"2026092423210397400_dmag027-B154","doi-asserted-by":"crossref","first-page":"103910","DOI":"10.1016\/j.rbmo.2024.103910","article-title":"Evaluation of an artificial intelligence-facilitated sperm detection tool in azoospermic samples for use in ICSI","volume":"49","author":"Goss","year":"2024","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B155","doi-asserted-by":"crossref","first-page":"100090","DOI":"10.1016\/j.cstres.2025.100090","article-title":"HSPA2 emerges as a key biomarker: insights from global lysine acetylproteomic profiling in idiopathic male infertility","volume":"30","author":"Goutami","year":"2025","journal-title":"Cell Stress Chaperones"},{"key":"2026092423210397400_dmag027-B156","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.3390\/jcm9061638","article-title":"Respiratory mitochondrial efficiency and DNA oxidation in human sperm after in vitro Myo-inositol treatment","volume":"9","author":"Governini","year":"2020","journal-title":"J Clin Med"},{"key":"2026092423210397400_dmag027-B157","first-page":"9","article-title":"Decrease of hypochlorous acid and hydroxyl radical generated by stimulated human neutrophils: comparison in vitro of some thiol-containing drugs","volume":"16","author":"Gressier","year":"1994","journal-title":"Methods Find Exp Clin Pharmacol"},{"key":"2026092423210397400_dmag027-B158","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5653\/cerm.2023.06009","article-title":"Criteria for implementing artificial intelligence systems in reproductive medicine","volume":"51","author":"Guell","year":"2024","journal-title":"Clin Exp Reprod Med"},{"key":"2026092423210397400_dmag027-B159","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/aje\/kwv135","article-title":"Association between use of Marijuana and male reproductive hormones and semen quality: a study among 1,215 healthy young men","volume":"182","author":"Gundersen","year":"2015","journal-title":"Am J Epidemiol"},{"key":"2026092423210397400_dmag027-B160","doi-asserted-by":"crossref","first-page":"e13124","DOI":"10.1111\/and.13124","article-title":"Smoking-induced genetic and epigenetic alterations in infertile men","volume":"50","author":"Gunes","year":"2018","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B161","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1093\/humupd\/dmx005","article-title":"Men\u2019s knowledge, attitudes and behaviours relating to fertility","volume":"23","author":"Hammarberg","year":"2017","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B162","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.rbms.2017.06.002","article-title":"Development of a health promotion programme to improve awareness of factors that affect fertility, and evaluation of its reach in the first 5 years","volume":"4","author":"Hammarberg","year":"2017","journal-title":"Reprod Biomed Soc Online"},{"key":"2026092423210397400_dmag027-B163","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.fertnstert.2012.10.031","article-title":"Knowledge about factors that influence fertility among Australians of reproductive age: a population-based survey","volume":"99","author":"Hammarberg","year":"2013","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B164","doi-asserted-by":"crossref","first-page":"hoab031","DOI":"10.1093\/hropen\/hoab031","article-title":"The International Fertility Education Initiative: research and action to improve fertility awareness","volume":"2021","author":"Harper","year":"2021","journal-title":"Hum Reprod Open"},{"key":"2026092423210397400_dmag027-B165","author":"Healthy Male","year":"2025"},{"key":"2026092423210397400_dmag027-B166","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/1477-7827-1-108","article-title":"Sperm preparation for ART","volume":"1","author":"Henkel","year":"2003","journal-title":"Reprod Biol Endocrinol"},{"key":"2026092423210397400_dmag027-B167","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S0015-0282(16)56296-7","article-title":"Cryopreservation of human spermatozoa. IV. The effects of cooling rate and warming rate on the maintenance of motility, plasma membrane integrity, and mitochondrial function","volume":"60","author":"Henry","year":"1993","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B168","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.fertnstert.2005.06.049","article-title":"Cryopreservation of spermatozoa in alginic acid capsules","volume":"85","author":"Herrler","year":"2006","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B169","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.rbmo.2018.05.012","article-title":"Sperm cryopreservation: a review on current molecular cryobiology and advanced approaches","volume":"37","author":"Hezavehei","year":"2018","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B170","doi-asserted-by":"crossref","first-page":"16770","DOI":"10.1038\/s41598-019-53217-y","article-title":"Machine learning-based analysis of sperm videos and participant data for male fertility prediction","volume":"9","author":"Hicks","year":"2019","journal-title":"Sci Rep"},{"key":"2026092423210397400_dmag027-B171","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1146\/annurev.nu.06.070186.003023","article-title":"Metabolism and function of Myo-inositol and inositol phospholipids","volume":"6","author":"Holub","year":"1986","journal-title":"Annu Rev Nutr"},{"key":"2026092423210397400_dmag027-B172","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/humupd\/dmab030","article-title":"A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene-disease relationships","volume":"28","author":"Houston","year":"2021","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B173","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/S0015-0282(99)00612-3","article-title":"Cryopreservation of human spermatozoa within human or mouse empty zona pellucidae","volume":"73","author":"Hsieh","year":"2000","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B174","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s10561-020-09860-1","article-title":"Comparison of rapid freezing versus vitrification for human sperm cryopreservation using sucrose in closed straw systems","volume":"21","author":"Hu","year":"2020","journal-title":"Cell Tissue Bank"},{"key":"2026092423210397400_dmag027-B175","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.fertnstert.2020.03.032","article-title":"Novel micro-straw for freezing small quantities of human spermatozoa","volume":"114","author":"Huang","year":"2020","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B176","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1093\/humrep\/13.5.1240","article-title":"The effects of antioxidant supplementation during Percoll preparation on human sperm DNA integrity","volume":"13","author":"Hughes","year":"1998","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B177","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3390\/antiox13020247","article-title":"Addition of vitamin C mitigates the loss of antioxidant capacity, vitality and DNA integrity in cryopreserved human semen samples","volume":"13","author":"Hungerford","year":"2024","journal-title":"Antioxidants (Basel)"},{"key":"2026092423210397400_dmag027-B178","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1038\/s41591-024-03166-5","article-title":"Deep learning versus manual morphology-based embryo selection in IVF: a randomized, double-blind noninferiority trial","volume":"30","author":"Illingworth","year":"2024","journal-title":"Nat Med"},{"key":"2026092423210397400_dmag027-B179","volume-title":"Crossing the Quality Chasm: A New Health System for the 21st Century","author":"Institute of Medicine (US) Committee on Quality of Health Care in America","year":"2001"},{"key":"2026092423210397400_dmag027-B180","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.bbrc.2017.10.112","article-title":"Supplementing zinc oxide nanoparticles to cryopreservation medium minimizes the freeze-thaw-induced damage to spermatozoa","volume":"494","author":"Isaac","year":"2017","journal-title":"Biochem Biophys Res Commun"},{"key":"2026092423210397400_dmag027-B181","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1530\/REP-07-0463","article-title":"Acrosomal status and mitochondrial activity of human spermatozoa vitrified with sucrose","volume":"136","author":"Isachenko","year":"2008","journal-title":"Reproduction"},{"key":"2026092423210397400_dmag027-B182","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/S1472-6483(10)61795-6","article-title":"Clean technique for cryoprotectant-free vitrification of human spermatozoa","volume":"10","author":"Isachenko","year":"2005","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B183","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1071\/RD11061","article-title":"Human spermatozoa vitrified in the absence of permeable cryoprotectants: birth of two healthy babies","volume":"24","author":"Isachenko","year":"2012","journal-title":"Reprod Fertil Dev"},{"key":"2026092423210397400_dmag027-B184","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1093\/humrep\/deab034","article-title":"Maternal occupational exposure to endocrine-disrupting chemicals during pregnancy and semen parameters in adulthood: results of a nationwide cross-sectional study among Swiss conscripts","volume":"36","author":"Istvan","year":"2021","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B185","doi-asserted-by":"crossref","first-page":"e14612","DOI":"10.1111\/and.14612","article-title":"N-acetyl-l-cysteine and alpha lipoic acid are protective supplement on human sperm parameters in cryopreservation of asthenoteratozoospermia patients","volume":"54","author":"Jannatifar","year":"2022","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B186","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.compbiomed.2019.04.030","article-title":"A novel deep learning method for automatic assessment of human sperm images","volume":"109","author":"Javadi","year":"2019","journal-title":"Comput Biol Med"},{"key":"2026092423210397400_dmag027-B187","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/cen.14213","article-title":"Burdens and awareness of adverse self-reported lifestyle factors in men with sub-fertility: a cross-sectional study in 1149 men","volume":"93","author":"Jayasena","year":"2020","journal-title":"Clin Endocrinol (Oxf)"},{"key":"2026092423210397400_dmag027-B188","doi-asserted-by":"crossref","first-page":"e14619","DOI":"10.1111\/and.14619","article-title":"A novel solution for freezing individual spermatozoa using a right angular cryopiece embedded in a grooved petri dish","volume":"54","author":"Jiang","year":"2022","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B189","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.fertnstert.2023.05.149","article-title":"Artificial intelligence in the in vitro fertilization laboratory: a review of advancements over the last decade","volume":"120","author":"Jiang","year":"2023","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B190","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s00441-015-2237-1","article-title":"The protein and transcript profiles of human semen","volume":"363","author":"Jodar","year":"2016","journal-title":"Cell Tissue Res"},{"key":"2026092423210397400_dmag027-B191","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.jprot.2016.08.018","article-title":"Semen proteomics and male infertility","volume":"162","author":"Jodar","year":"2017","journal-title":"J Proteomics"},{"key":"2026092423210397400_dmag027-B192","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.arr.2014.10.007","article-title":"Consistent age-dependent declines in human semen quality: a systematic review and meta-analysis","volume":"19","author":"Johnson","year":"2015","journal-title":"Ageing Res Rev"},{"key":"2026092423210397400_dmag027-B193","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.fertnstert.2003.12.050","article-title":"Novel method for the cryopreservation of testicular sperm and ejaculated spermatozoa from patients with severe oligospermia: a pilot study","volume":"82","author":"Just","year":"2004","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B194","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1111\/andr.13725","article-title":"Sperm chromatin dispersion assay reliability and assisted reproductive technology outcomes: systematic review and meta-analysis","volume":"13","author":"Kaiyal","year":"2025","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B195","doi-asserted-by":"crossref","first-page":"1520919","DOI":"10.3389\/frph.2025.1520919","article-title":"The integration of artificial intelligence in assisted reproduction: a comprehensive review","volume":"7","author":"Kakkar","year":"2025","journal-title":"Front Reprod Health"},{"key":"2026092423210397400_dmag027-B196","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.fertnstert.2010.10.005","article-title":"Vitamin E supplementation in semen-freezing medium improves the motility and protects sperm from freeze-thaw-induced DNA damage","volume":"95","author":"Kalthur","year":"2011","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B197","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s10815-012-9760-8","article-title":"Supplementation of biotin to sperm preparation medium increases the motility and longevity in cryopreserved human spermatozoa","volume":"29","author":"Kalthur","year":"2012","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B198","doi-asserted-by":"crossref","first-page":"486","DOI":"10.3390\/genes14020486","article-title":"Impact of advanced paternal age on fertility and risks of genetic disorders in offspring","volume":"14","author":"Kaltsas","year":"2023","journal-title":"Genes (Basel)"},{"key":"2026092423210397400_dmag027-B199","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3390\/biomedicines14020259","article-title":"Psychological stress and male infertility: oxidative stress as the common downstream pathway","volume":"14","author":"Kaltsas","year":"2026","journal-title":"Biomedicines"},{"key":"2026092423210397400_dmag027-B200","doi-asserted-by":"crossref","first-page":"10602","DOI":"10.1038\/s41598-018-28896-8","article-title":"Assessing the tolerance to room temperature and viability of freeze-dried mice spermatozoa over long-term storage at room temperature under vacuum","volume":"8","author":"Kamada","year":"2018","journal-title":"Sci Rep"},{"key":"2026092423210397400_dmag027-B201","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.cryobiol.2012.01.010","article-title":"Long-term preservation of freeze-dried mouse spermatozoa","volume":"64","author":"Kaneko","year":"2012","journal-title":"Cryobiology"},{"key":"2026092423210397400_dmag027-B202","doi-asserted-by":"crossref","first-page":"e12482","DOI":"10.1002\/rmb2.12482","article-title":"High concentration of dopamine treatment may induce acceleration of human sperm motility","volume":"21","author":"Kanno","year":"2022","journal-title":"Reprod Med Biol"},{"key":"2026092423210397400_dmag027-B203","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1177\/0394632015572080","article-title":"The protective effects of melatonin against cryopreservation-induced oxidative stress in human sperm","volume":"28","author":"Karimfar","year":"2015","journal-title":"Int J Immunopathol Pharmacol"},{"key":"2026092423210397400_dmag027-B204","doi-asserted-by":"crossref","first-page":"653","DOI":"10.5694\/mja2.70080","article-title":"The first Australian evidence-based guidelines on male infertility","volume":"223","author":"Katz","year":"2025","journal-title":"Med J Aust"},{"key":"2026092423210397400_dmag027-B205","doi-asserted-by":"crossref","first-page":"925","DOI":"10.3109\/10715762.2011.564168","article-title":"Antioxidant and anti-proliferative properties of lycopene","volume":"45","author":"Kelkel","year":"2011","journal-title":"Free Radic Res"},{"key":"2026092423210397400_dmag027-B206","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1093\/humrep\/deaf183","article-title":"A prospective randomized controlled trial of antioxidants in human IVF and embryo culture media","volume":"40","author":"Kelley","year":"2025","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B207","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1111\/j.1439-0272.2011.01256.x","article-title":"In vitro effects of alpha-tocopherol on teratozoospermic semen samples","volume":"44","author":"Keshtgar","year":"2012","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B208","first-page":"1250","article-title":"Progesterone, Myo-inositol, dopamine and prolactin present in follicular fluid have differential effects on sperm motility subpopulations","volume":"11","author":"Keyser","year":"2021","journal-title":"Life (Basel)"},{"key":"2026092423210397400_dmag027-B209","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/s41585-023-00820-4","article-title":"Frequency, morbidity and equity: the case for increased research on male fertility","volume":"21","author":"Kimmins","year":"2024","journal-title":"Nat Rev Urol"},{"key":"2026092423210397400_dmag027-B210","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3310\/eme06010","article-title":"Sperm selection for assisted reproduction by prior hyaluronan binding: the HABSelect RCT","volume":"6","author":"Kirkman-Brown","year":"2019","journal-title":"Efficacy Mech Eval"},{"key":"2026092423210397400_dmag027-B211","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/j.fertnstert.2012.12.020","article-title":"Intracytoplasmic morphologically selected sperm injection versus intracytoplasmic sperm injection: a step toward a clinical algorithm","volume":"99","author":"Klement","year":"2013","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B212","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1177\/2472630318783948","article-title":"Design, fabrication, and testing of a microfluidic device for thermotaxis and chemotaxis assays of sperm","volume":"23","author":"Ko","year":"2018","journal-title":"SLAS Technol"},{"key":"2026092423210397400_dmag027-B213","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1093\/hmg\/ddm187","article-title":"Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients","volume":"16","author":"Kobayashi","year":"2007","journal-title":"Hum Mol Genet"},{"key":"2026092423210397400_dmag027-B214","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0022-5347(05)66104-6","article-title":"Significant medical pathology discovered during a male infertility evaluation","volume":"166","author":"Kolettis","year":"2001","journal-title":"J Urol"},{"key":"2026092423210397400_dmag027-B215","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/nature11396","article-title":"Rate of de novo mutations and the importance of father\u2019s age to disease risk","volume":"488","author":"Kong","year":"2012","journal-title":"Nature"},{"key":"2026092423210397400_dmag027-B216","doi-asserted-by":"crossref","first-page":"e13870","DOI":"10.1111\/and.13870","article-title":"The effect of cysteine and glutamine on human sperm functional parameters during vitrification","volume":"53","author":"Koohestanidehaghi","year":"2021","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B217","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1007\/s10815-012-9894-8","article-title":"Addition of zinc to human ejaculate prior to cryopreservation prevents freeze-thaw-induced DNA damage and preserves sperm function","volume":"29","author":"Kotdawala","year":"2012","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B218","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1080\/15325024.2015.1057451","article-title":"Effects of a self-help program on depressed mood for women with an unfulfilled child wish","volume":"21","author":"Kraaij","year":"2016","journal-title":"J Loss Trauma"},{"key":"2026092423210397400_dmag027-B219","doi-asserted-by":"crossref","first-page":"13501","DOI":"10.1073\/pnas.241517598","article-title":"Maintenance of genetic integrity in frozen and freeze-dried mouse spermatozoa","volume":"98","author":"Kusakabe","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"2026092423210397400_dmag027-B220","doi-asserted-by":"crossref","first-page":"105342","DOI":"10.1016\/j.rbmo.2025.105342","article-title":"Parenthood intentions and fertility knowledge in the Nordic population 1970 to 2021 - a scoping review","volume":"52","author":"Lakjuni","year":"2026","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B221","doi-asserted-by":"crossref","first-page":"e8148","DOI":"10.48101\/ujms.v126.8148","article-title":"Fertility awareness and intentions among young adults in Greece","volume":"126","author":"Lardou","year":"2021","journal-title":"Ups J Med Sci"},{"key":"2026092423210397400_dmag027-B222","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1080\/14647273.2022.2163466","article-title":"Young men\u2019s perceptions and attitudes towards two fertility awareness interventions and preferences for future initiatives","volume":"26","author":"Larsen","year":"2023","journal-title":"Hum Fertil (Camb)"},{"key":"2026092423210397400_dmag027-B223","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1093\/humrep\/15.7.1562","article-title":"Computer-assisted semen analysis parameters as predictors for fertility of men from the general population. The Danish First Pregnancy Planner Study Team","volume":"15","author":"Larsen","year":"2000","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B224","doi-asserted-by":"crossref","first-page":"4235","DOI":"10.1038\/s41598-023-31136-3","article-title":"Development and validation of deep learning based embryo selection across multiple days of transfer","volume":"13","author":"Lassen","year":"2023","journal-title":"Sci Rep"},{"key":"2026092423210397400_dmag027-B225","doi-asserted-by":"crossref","first-page":"70","DOI":"10.5935\/1518-0557.20150016","article-title":"Relationship between sperm DNA fragmentation and nuclear vacuoles","volume":"19","author":"Lavolpe","year":"2015","journal-title":"JBRA Assist Reprod"},{"key":"2026092423210397400_dmag027-B226","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1002\/j.1939-4640.2000.tb03424.x","article-title":"The cyclic GMP-specific phosphodiesterase inhibitor, sildenafil, stimulates human sperm motility and capacitation but not acrosome reaction","volume":"21","author":"Lefievre","year":"2000","journal-title":"J Androl"},{"key":"2026092423210397400_dmag027-B227","first-page":"CD010461","article-title":"Advanced sperm selection techniques for assisted reproduction","volume":"7","author":"Lepine","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"2026092423210397400_dmag027-B228","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.fertnstert.2020.06.006","article-title":"Artificial intelligence in in vitro fertilization: a computer decision support system for day-to-day management of ovarian stimulation during in vitro fertilization","volume":"114","author":"Letterie","year":"2020","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B229","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s41585-021-00530-9","article-title":"Simulating nature in sperm selection for assisted reproduction","volume":"19","author":"Leung","year":"2022","journal-title":"Nat Rev Urol"},{"key":"2026092423210397400_dmag027-B230","first-page":"195","article-title":"Cryopreservation of a small number of spermatozoa in yolk-filled human zonae pellucidae","volume":"75","author":"Levi-Setti","year":"2003","journal-title":"Arch Ital Urol Androl"},{"key":"2026092423210397400_dmag027-B231","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1093\/humupd\/dmac035","article-title":"Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries","volume":"29","author":"Levine","year":"2023","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B232","doi-asserted-by":"crossref","first-page":"S213","DOI":"10.1016\/S0098-2997(97)00036-8","article-title":"The effect of coenzyme Q10 on sperm motility and function","volume":"18","author":"Lewin","year":"1997","journal-title":"Mol Aspects Med"},{"key":"2026092423210397400_dmag027-B233","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3109\/01485019408987784","article-title":"Influence of pentoxifylline on human sperm motility in asthenozoospermic individuals using computer-assisted analysis","volume":"32","author":"Lewis","year":"1994","journal-title":"Arch Androl"},{"key":"2026092423210397400_dmag027-B234","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/s41598-023-45091-6","article-title":"Sperm DNA fragmentation index affect pregnancy outcomes and offspring safety in assisted reproductive technology","volume":"14","author":"Li","year":"2024","journal-title":"Sci Rep"},{"key":"2026092423210397400_dmag027-B235","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1095\/biolreprod12.5.641","article-title":"The glutathione and thiol content of mammalian spermatozoa and seminal plasma","volume":"12","author":"Li","year":"1975","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B236","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ejogrb.2019.06.021","article-title":"Evaluation and improvement of the novel method for vitrification of a few human sperms","volume":"240","author":"Li","year":"2019","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2026092423210397400_dmag027-B237","doi-asserted-by":"crossref","first-page":"437","DOI":"10.2164\/jandrol.109.007849","article-title":"Protective effects of ascorbate and catalase on human spermatozoa during cryopreservation","volume":"31","author":"Li","year":"2010","journal-title":"J Androl"},{"key":"2026092423210397400_dmag027-B238","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12958-020-00607-x","article-title":"Cryopreservation of single-sperm: where are we today?","volume":"18","author":"Liu","year":"2020","journal-title":"Reprod Biol Endocrinol"},{"key":"2026092423210397400_dmag027-B239","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.bbrc.2017.01.010","article-title":"Luteinizing hormone modulates intracellular calcium, protein tyrosine phosphorylation and motility during human sperm capacitation","volume":"483","author":"Lopez-Torres","year":"2017","journal-title":"Biochem Biophys Res Commun"},{"key":"2026092423210397400_dmag027-B240","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s10815-023-02973-y","article-title":"Artificial intelligence in time-lapse system: advances, applications, and future perspectives in reproductive medicine","volume":"41","author":"Luong","year":"2024","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B241","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1093\/humrep\/deab124","article-title":"Temporal trends in semen concentration and count among 327 373 Chinese healthy men from 1981 to 2019: a systematic review","volume":"36","author":"Lv","year":"2021","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B242","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/s41585-025-01047-1","article-title":"Unlocking the power of semen analysis in primary health care - a path to men\u2019s health and lifestyle transformation","volume":"22","author":"Lyons","year":"2025","journal-title":"Nat Rev Urol"},{"key":"2026092423210397400_dmag027-B243","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0015-0282(16)43808-2","article-title":"Male fertility potential in terms of semen quality: a review of the past, a study of the present","volume":"31","author":"MacLeod","year":"1979","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B244","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1742-4755-12-10","article-title":"A cross sectional study on fertility knowledge in Japan, measured with the Japanese version of Cardiff Fertility Knowledge Scale (CFKS-J)","volume":"12","author":"Maeda","year":"2015","journal-title":"Reprod Health"},{"key":"2026092423210397400_dmag027-B245","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cryobiol.2021.11.176","article-title":"Single sperm vitrification with permeable cryoprotectant-free medium is more effective in patients with severe oligozoospermia and azoospermia","volume":"104","author":"Maleki","year":"2022","journal-title":"Cryobiology"},{"key":"2026092423210397400_dmag027-B246","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.fertnstert.2012.05.006","article-title":"Ten years\u2019 experience with an external quality control program for semen analysis","volume":"98","author":"Mallidis","year":"2012","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B247","doi-asserted-by":"crossref","first-page":"e13944","DOI":"10.1111\/and.13944","article-title":"Ameliorative effect of melatonin on apoptosis, DNA fragmentation, membrane integrity and lipid peroxidation of spermatozoa in the idiopathic asthenoteratospermic men: in vitro","volume":"53","author":"Malmir","year":"2021","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B248","doi-asserted-by":"crossref","first-page":"s249","DOI":"10.1016\/0098-2997(94)90035-3","article-title":"Coenzyme Q10 levels in human seminal fluid: diagnostic and clinical implications","volume":"15","author":"Mancini","year":"1994","journal-title":"Mol Aspects Med"},{"key":"2026092423210397400_dmag027-B249","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.tjog.2018.02.006","article-title":"Vitamin C attenuates negative effects of vitrification on sperm parameters, chromatin quality, apoptosis and acrosome reaction in neat and prepared normozoospermic samples","volume":"57","author":"Mangoli","year":"2018","journal-title":"Taiwan J Obstet Gynecol"},{"key":"2026092423210397400_dmag027-B250","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.fertnstert.2006.11.176","article-title":"The impact of spermatozoa preincubation time and spontaneous acrosome reaction in intracytoplasmic sperm injection: a controlled randomized study","volume":"90","author":"Mansour","year":"2008","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B251","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.fertnstert.2021.03.033","article-title":"Influence of paternal age on assisted reproductive technology cycles and perinatal outcomes","volume":"116","author":"Marsidi","year":"2021","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B252","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1093\/humupd\/dmw009","article-title":"Male psychological adaptation to unsuccessful medically assisted reproduction treatments: a systematic review","volume":"22","author":"Martins","year":"2016","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B253","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/humrep\/dead253","article-title":"Fertility education: recommendations for developing and implementing tools to improve fertility literacydagger","volume":"39","author":"Martins","year":"2024","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B254","doi-asserted-by":"crossref","first-page":"107498","DOI":"10.1016\/j.biotechadv.2019.107498","article-title":"Sperm selection in assisted reproduction: a review of established methods and cutting-edge possibilities","volume":"40","author":"Marzano","year":"2020","journal-title":"Biotechnol Adv"},{"key":"2026092423210397400_dmag027-B255","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.fertnstert.2017.08.033","article-title":"Effect of the male factor on the clinical outcome of intracytoplasmic sperm injection combined with preimplantation aneuploidy testing: observational longitudinal cohort study of 1,219 consecutive cycles","volume":"108","author":"Mazzilli","year":"2017","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B256","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1007\/s40618-022-02000-4","article-title":"Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes","volume":"46","author":"Mazzilli","year":"2023","journal-title":"J Endocrinol Invest"},{"key":"2026092423210397400_dmag027-B257","author":"McKercher","year":"2024"},{"key":"2026092423210397400_dmag027-B258","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1439-0272.1994.tb00794.x","article-title":"Persistent effects of pentoxifylline on human sperm motility, after drug removal, in normozoospermic and asthenozoospermic individuals","volume":"26","author":"McKinney","year":"1994","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B259","doi-asserted-by":"crossref","first-page":"103625","DOI":"10.1016\/j.rbmo.2023.103625","article-title":"Clinical use of progesterone in human sperm preparation media for increasing IVF success","volume":"48","author":"McPherson","year":"2024","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B260","doi-asserted-by":"crossref","first-page":"367","DOI":"10.4103\/aja202161","article-title":"Magnetic-activated cell sorting of nonapoptotic spermatozoa with a high DNA fragmentation index improves the live birth rate and decreases transfer cycles of IVF\/ICSI","volume":"24","author":"Mei","year":"2022","journal-title":"Asian J Androl"},{"key":"2026092423210397400_dmag027-B261","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.rbmo.2022.03.036","article-title":"Computer software (SiD) assisted real-time single sperm selection associated with fertilization and blastocyst formation","volume":"45","author":"Mendizabal-Ruiz","year":"2022","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B262","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/humrep\/dead235","article-title":"The influence of male HBV infection on sperm quality, embryonic development, and assisted reproductive outcomes","volume":"39","author":"Meng","year":"2024","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B263","doi-asserted-by":"crossref","first-page":"hoad009","DOI":"10.1093\/hropen\/hoad009","article-title":"Stimulating fertility awareness: the importance of getting the language right","volume":"2023","author":"Mertes","year":"2023","journal-title":"Hum Reprod Open"},{"key":"2026092423210397400_dmag027-B264","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/S0140-6736(18)32989-1","article-title":"Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial","volume":"393","author":"Miller","year":"2019","journal-title":"Lancet"},{"key":"2026092423210397400_dmag027-B265","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1146\/annurev-animal-021022-040629","article-title":"Sperm in the mammalian female reproductive tract: surfing through the tract to try to beat the odds","volume":"12","author":"Miller","year":"2024","journal-title":"Annu Rev Anim Biosci"},{"key":"2026092423210397400_dmag027-B266","first-page":"99","article-title":"Effect of Trolox addition to cryopreservation media on human sperm motility","volume":"10","author":"Minaei","year":"2012","journal-title":"Iran J Reprod Med"},{"key":"2026092423210397400_dmag027-B267","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.eururo.2025.02.026","article-title":"European Association of Urology Guidelines on Male Sexual and Reproductive Health: 2025 update on male infertility","volume":"87","author":"Minhas","year":"2025","journal-title":"Eur Urol"},{"key":"2026092423210397400_dmag027-B268","doi-asserted-by":"crossref","first-page":"5128","DOI":"10.3390\/ijms23095128","article-title":"New insight on the in vitro effects of melatonin in preserving human sperm quality","volume":"23","author":"Minucci","year":"2022","journal-title":"Int J Mol Sci"},{"key":"2026092423210397400_dmag027-B269","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1002\/cyto.a.23189","article-title":"Automated analysis of individual sperm cells using stain-free interferometric phase microscopy and machine learning","volume":"91","author":"Mirsky","year":"2017","journal-title":"Cytometry A"},{"key":"2026092423210397400_dmag027-B270","doi-asserted-by":"crossref","first-page":"104415","DOI":"10.1016\/j.rbmo.2024.104415","article-title":"Culture media with antioxidants improved preimplantation embryo development and clinical outcomes of patients of advanced age","volume":"50","author":"Mizumoto","year":"2025","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B271","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/BF02216028","article-title":"Effects of pentoxifylline on human sperm parameters in vitro","volume":"11","author":"Mladenovic","year":"1994","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B272","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s10561-018-9731-0","article-title":"Supplementation of sperm freezing medium with Myoinositol improve human sperm parameters and protects it against DNA fragmentation and apoptosis","volume":"20","author":"Mohammadi","year":"2019","journal-title":"Cell Tissue Bank"},{"key":"2026092423210397400_dmag027-B273","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1046\/j.1439-0272.1999.00236.x","article-title":"Laser-assisted cryopreservation of single human spermatozoa in cell-free zona pellucida","volume":"31","author":"Montag","year":"1999","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B274","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3390\/antiox13040439","article-title":"Antioxidant actions of melatonin: a systematic review of animal studies","volume":"13","author":"Monteiro","year":"2024","journal-title":"Antioxidants (Basel)"},{"key":"2026092423210397400_dmag027-B275","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.3390\/antiox12051098","article-title":"Human Sperm as an in vitro model to assess the efficacy of antioxidant supplements during sperm handling: a narrative review","volume":"12","author":"Moretti","year":"2023","journal-title":"Antioxidants (Basel)"},{"key":"2026092423210397400_dmag027-B276","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1111\/aogs.14221","article-title":"Paternal age over 50 years decreases assisted reproductive technology (ART) success: a single UK center retrospective analysis","volume":"100","author":"Morris","year":"2021","journal-title":"Acta Obstet Gynecol Scand"},{"key":"2026092423210397400_dmag027-B277","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1093\/humrep\/del116","article-title":"Rapidly cooled human sperm: no evidence of intracellular ice formation","volume":"21","author":"Morris","year":"2006","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B278","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1439-0272.2012.01310.x","article-title":"Catalase improves motility, vitality and DNA integrity of cryopreserved human spermatozoa","volume":"45","author":"Moubasher","year":"2013","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B279","doi-asserted-by":"crossref","first-page":"268","DOI":"10.4103\/jhrs.jhrs_90_23","article-title":"Use of anabolic-androgenic steroids and male fertility: a systematic review and meta-analysis","volume":"16","author":"Mulawkar","year":"2023","journal-title":"J Hum Reprod Sci"},{"key":"2026092423210397400_dmag027-B280","doi-asserted-by":"crossref","first-page":"e13932","DOI":"10.1111\/and.13932","article-title":"Protective effect of L-carnitine on apoptosis, DNA fragmentation, membrane integrity and Lipid peroxidation of spermatozoa in the asthenoteratospermic men","volume":"53","author":"Naderi Noreini","year":"2021","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B281","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00441-017-2743-4","article-title":"Melatonin affects membrane integrity, intracellular reactive oxygen species, caspase3 activity and AKT phosphorylation in frozen thawed human sperm","volume":"372","author":"Najafi","year":"2018","journal-title":"Cell Tissue Res"},{"key":"2026092423210397400_dmag027-B282","doi-asserted-by":"crossref","first-page":"1700550","DOI":"10.1002\/adhm.201700550","article-title":"Organ-on-a-chip systems for women\u2019s health applications","volume":"7","author":"Nawroth","year":"2018","journal-title":"Adv Healthc Mater"},{"key":"2026092423210397400_dmag027-B283","doi-asserted-by":"crossref","first-page":"hoae066","DOI":"10.1093\/hropen\/hoae066","article-title":"Lab-based semen parameters as predictors of long-term health in men-a systematic review","volume":"2024","author":"Nedelcu","year":"2024","journal-title":"Hum Reprod Open"},{"key":"2026092423210397400_dmag027-B284","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.cryobiol.2016.02.008","article-title":"Effect of Trolox on sperm quality in normozospermia and oligozospermia during cryopreservation","volume":"72","author":"Nekoonam","year":"2016","journal-title":"Cryobiology"},{"key":"2026092423210397400_dmag027-B285","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0015-0282(16)40454-1","article-title":"Semen analysis: evidence for changing parameters of male fertility potential","volume":"25","author":"Nelson","year":"1974","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B286","volume-title":"Assisted Reproductive Technology in Australia and New Zealand 2020","author":"Newman","year":"2020"},{"key":"2026092423210397400_dmag027-B287","doi-asserted-by":"crossref","first-page":"568","DOI":"10.4103\/1008-682X.151395","article-title":"The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition","volume":"17","author":"Nixon","year":"2015","journal-title":"Asian J Androl"},{"key":"2026092423210397400_dmag027-B288","doi-asserted-by":"crossref","first-page":"1145533","DOI":"10.3389\/fendo.2023.1145533","article-title":"New horizons in human sperm selection for assisted reproduction","volume":"14","author":"Nixon","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2026092423210397400_dmag027-B289","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/nrurol.2017.175","article-title":"Microfluidics for sperm analysis and selection","volume":"14","author":"Nosrati","year":"2017","journal-title":"Nat Rev Urol"},{"key":"2026092423210397400_dmag027-B290","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1039\/c3lc51254a","article-title":"Rapid selection of sperm with high DNA integrity","volume":"14","author":"Nosrati","year":"2014","journal-title":"Lab Chip"},{"key":"2026092423210397400_dmag027-B291","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1002\/cyto.a.24703","article-title":"Sperm-cell DNA fragmentation prediction using label-free quantitative phase imaging and deep learning","volume":"103","author":"Noy","year":"2023","journal-title":"Cytometry A"},{"key":"2026092423210397400_dmag027-B292","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1007\/s10815-019-01505-x","article-title":"Improved cryopreservation of spermatozoa using vitrification: comparison of cryoprotectants and a novel device for long-term storage","volume":"36","author":"O\u2019Neill","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B293","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1439-0272.1997.tb00305.x","article-title":"Scavenging effect of N-acetyl-L-cysteine against reactive oxygen species in human semen: a possible therapeutic modality for male factor infertility?","volume":"29","author":"Oeda","year":"1997","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B294","doi-asserted-by":"crossref","first-page":"104644","DOI":"10.1016\/j.isci.2022.104644","article-title":"motilitAI: a machine learning framework for automatic prediction of human sperm motility","volume":"25","author":"Ottl","year":"2022","journal-title":"iScience"},{"key":"2026092423210397400_dmag027-B295","doi-asserted-by":"crossref","first-page":"4716","DOI":"10.3390\/cimb45060300","article-title":"Sperm cryopreservation today: approaches, efficiency, and pitfalls","volume":"45","author":"Ozimic","year":"2023","journal-title":"Curr Issues Mol Biol"},{"key":"2026092423210397400_dmag027-B296","doi-asserted-by":"crossref","first-page":"3976","DOI":"10.3390\/jcm9123976","article-title":"Magnetic-Activated Cell Sorting (MACS): a useful sperm-selection technique in cases of high levels of sperm DNA fragmentation","volume":"9","author":"Pacheco","year":"2020","journal-title":"J Clin Med"},{"key":"2026092423210397400_dmag027-B297","doi-asserted-by":"crossref","first-page":"e13711","DOI":"10.1111\/and.13711","article-title":"Proteomics and metabolomics - current and future perspectives in clinical andrology","volume":"53","author":"Panner Selvam","year":"2021","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B298","doi-asserted-by":"crossref","first-page":"6472945","DOI":"10.1155\/2019\/6472945","article-title":"Melatonin and caffeine supplementation used, respectively, as protective and stimulating agents in the cryopreservation of human sperm improves survival, viability, and motility after thawing compared to traditional TEST-Yolk Buffer","volume":"2019","author":"Pariz","year":"2019","journal-title":"Oxid Med Cell Longev"},{"key":"2026092423210397400_dmag027-B299","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.fertnstert.2009.03.033","article-title":"\"Physiologic ICSI\": hyaluronic acid (HA) favors selection of spermatozoa without DNA fragmentation and with normal nucleus, resulting in improvement of embryo quality","volume":"93","author":"Parmegiani","year":"2010","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B300","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/j.1939-4640.2000.tb02144.x","article-title":"Effect of pentoxifylline on the intrinsic swimming forces of human sperm assessed by optical tweezers","volume":"21","author":"Patrizio","year":"2000","journal-title":"J Androl"},{"key":"2026092423210397400_dmag027-B301","doi-asserted-by":"crossref","first-page":"100621","DOI":"10.1016\/j.srhc.2021.100621","article-title":"Australian men\u2019s fertility information seeking attitudes and behaviour: a qualitative investigation","volume":"29","author":"Pearson","year":"2021","journal-title":"Sex Reprod Healthc"},{"key":"2026092423210397400_dmag027-B302","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1080\/03009734.2018.1480186","article-title":"What do people know about fertility? a systematic review on fertility awareness and its associated factors","volume":"123","author":"Pedro","year":"2018","journal-title":"Ups J Med Sci"},{"key":"2026092423210397400_dmag027-B303","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/s11626-011-9428-1","article-title":"A novel method for cryopreservation of individual human spermatozoa","volume":"47","author":"Peng","year":"2011","journal-title":"In Vitro Cell Dev Biol Anim"},{"key":"2026092423210397400_dmag027-B304","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1093\/humrep\/deaa373","article-title":"Social sperm freezing","volume":"36","author":"Pennings","year":"2021","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B305","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/humupd\/dmaf028","article-title":"Microfluidics for in vitro fertilization: from science to clinical validation","volume":"32","author":"Pensabene","year":"2026","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B306","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1365-2605.1994.tb01229.x","article-title":"Improvement in quality of cryopreserved human spermatozoa by swim-up before freezing","volume":"17","author":"Perez-Sanchez","year":"1994","journal-title":"Int J Androl"},{"key":"2026092423210397400_dmag027-B307","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1007\/s10815-014-0332-y","article-title":"Sperm preparation before freezing improves sperm motility and reduces apoptosis in post-freezing-thawing sperm compared with post-thawing sperm preparation","volume":"31","author":"Petyim","year":"2014","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B308","doi-asserted-by":"crossref","first-page":"e250105","DOI":"10.1530\/REP-25-0105","article-title":"Towards a kingdom of reproductive life - the core sperm proteome","volume":"169","author":"Pini","year":"2025","journal-title":"Reproduction"},{"key":"2026092423210397400_dmag027-B309","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.fertnstert.2022.01.018","article-title":"The ART of cryopreservation and its changing landscape","volume":"117","author":"Pomeroy","year":"2022","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B310","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3390\/antiox11010010","article-title":"Oxidative stress measurement in frozen\/thawed human sperm: the protective role of an in vitro treatment with Myo-inositol","volume":"11","author":"Ponchia","year":"2021","journal-title":"Antioxidants (Basel)"},{"key":"2026092423210397400_dmag027-B311","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12610-021-00144-6","article-title":"Beneficial effects of hypotaurine supplementation in preparation and freezing media on human sperm cryo-capacitation and DNA quality","volume":"31","author":"Pons-Rejraji","year":"2021","journal-title":"Basic Clin Androl"},{"key":"2026092423210397400_dmag027-B312","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3390\/s18113607","article-title":"Key enabling technologies for point-of-care diagnostics","volume":"18","author":"Primiceri","year":"2018","journal-title":"Sensors (Basel)"},{"key":"2026092423210397400_dmag027-B313","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1093\/humrep\/deaf023","article-title":"Semen quality and lifespan: a study of 78 284 men followed for up to 50 years","volume":"40","author":"Priskorn","year":"2025","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B314","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1210\/en.2009-0964","article-title":"Prolactin exerts a prosurvival effect on human spermatozoa via mechanisms that involve the stimulation of Akt phosphorylation and suppression of caspase activation and capacitation","volume":"151","author":"Pujianto","year":"2010","journal-title":"Endocrinology"},{"key":"2026092423210397400_dmag027-B315","doi-asserted-by":"crossref","first-page":"121","DOI":"10.4103\/jhrs.jhrs_241_20","article-title":"Hydrogen peroxide has adverse effects on human sperm quality parameters, induces apoptosis, and reduces survival","volume":"14","author":"Pujianto","year":"2021","journal-title":"J Hum Reprod Sci"},{"key":"2026092423210397400_dmag027-B316","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1111\/andr.12230","article-title":"Fifteen years of Belgian experience with external quality assessment of semen analysis","volume":"4","author":"Punjabi","year":"2016","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B317","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1146\/annurev-genet-022020-023434","article-title":"Canary in the coal mine? male infertility as a marker of overall health","volume":"54","author":"Punjani","year":"2020","journal-title":"Annu Rev Genet"},{"key":"2026092423210397400_dmag027-B318","doi-asserted-by":"crossref","first-page":"105124","DOI":"10.1016\/j.rbmo.2025.105124","article-title":"Analysis of antioxidant activity in commercial IVF media","volume":"52","author":"Pyneandee","year":"2026","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B319","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1111\/andr.12531","article-title":"Cryopreservation media differentially affect sperm motility, morphology and DNA integrity","volume":"6","author":"Raad","year":"2018","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B320","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.biotechadv.2016.01.007","article-title":"Sperm processing for advanced reproductive technologies: where are we today?","volume":"34","author":"Rappa","year":"2016","journal-title":"Biotechnol Adv"},{"key":"2026092423210397400_dmag027-B321","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/biolre\/ioad153","article-title":"Dopamine receptor D2 regulates genes involved in germ cell movement and sperm motility in rat testes","volume":"110","author":"Raut","year":"2024","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B322","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s12978-023-01628-6","article-title":"University students\u2019 fertility awareness and its influencing factors: a systematic review","volume":"20","author":"Ren","year":"2023","journal-title":"Reprod Health"},{"key":"2026092423210397400_dmag027-B323","doi-asserted-by":"crossref","first-page":"e44679","DOI":"10.1371\/journal.pone.0044679","article-title":"Double stranded sperm DNA breaks, measured by Comet assay, are associated with unexplained recurrent miscarriage in couples without a female factor","volume":"7","author":"Ribas-Maynou","year":"2012","journal-title":"PLoS One"},{"key":"2026092423210397400_dmag027-B324","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.rbmo.2016.09.012","article-title":"Semen quality and alcohol intake: a systematic review and meta-analysis","volume":"34","author":"Ricci","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B325","doi-asserted-by":"crossref","first-page":"hoac014","DOI":"10.1093\/hropen\/hoac014","article-title":"Protocol for developing a core outcome set for male infertility research: an international consensus development study","volume":"2022","author":"Rimmer","year":"2022","journal-title":"Hum Reprod Open"},{"key":"2026092423210397400_dmag027-B326","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.fertnstert.2025.03.009","article-title":"A core outcome set for future male infertility research: development of an international consensus","volume":"123","author":"Rimmer","year":"2025","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B327","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1093\/humrep\/des261","article-title":"The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis","volume":"27","author":"Robinson","year":"2012","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B328","doi-asserted-by":"crossref","first-page":"102298","DOI":"10.1016\/j.bpobgyn.2022.102298","article-title":"Environmental toxicants and male fertility","volume":"86","author":"Rodprasert","year":"2023","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"2026092423210397400_dmag027-B329","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1023\/A:1011592621487","article-title":"Improved human sperm recovery using superoxide dismutase and catalase supplementation in semen cryopreservation procedure","volume":"2","author":"Rossi","year":"2001","journal-title":"Cell Tissue Bank"},{"key":"2026092423210397400_dmag027-B330","first-page":"320","article-title":"Implications of lifestyle factors on male reproductive health","volume":"28","author":"Rotimi","year":"2024","journal-title":"JBRA Assist Reprod"},{"key":"2026092423210397400_dmag027-B331","doi-asserted-by":"crossref","first-page":"6142","DOI":"10.1016\/S0021-9258(18)42673-7","article-title":"Phospholipid hydroperoxide glutathione peroxidase of rat testis. Gonadotropin dependence and immunocytochemical identification","volume":"267","author":"Roveri","year":"1992","journal-title":"J Biol Chem"},{"key":"2026092423210397400_dmag027-B332","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1080\/19396368.2022.2119181","article-title":"Oxidative versus reductive stress: a delicate balance for sperm integrity","volume":"69","author":"Sadeghi","year":"2023","journal-title":"Syst Biol Reprod Med"},{"key":"2026092423210397400_dmag027-B333","doi-asserted-by":"crossref","first-page":"531","DOI":"10.3233\/THC-140816","article-title":"Seminal quality prediction using data mining methods","volume":"22","author":"Sahoo","year":"2014","journal-title":"Technol Health Care"},{"key":"2026092423210397400_dmag027-B334","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.rbmo.2010.05.011","article-title":"Implication of apoptosis in sperm cryoinjury","volume":"21","author":"Said","year":"2010","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B335","doi-asserted-by":"crossref","first-page":"177","DOI":"10.5653\/cerm.2018.45.4.177","article-title":"Increased cryo-survival rate in ejaculated human sperm from infertile men following pre-freeze in vitro Myo-inositol supplementation","volume":"45","author":"Saleh","year":"2018","journal-title":"Clin Exp Reprod Med"},{"key":"2026092423210397400_dmag027-B336","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s10815-018-1323-1","article-title":"Supplementation of biotin to sperm preparation medium enhances fertilizing ability of spermatozoa and improves preimplantation embryo development","volume":"36","author":"Salian","year":"2019","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B337","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.eururo.2009.03.001","article-title":"Are infertile men less healthy than fertile men? Results of a prospective case-control survey","volume":"56","author":"Salonia","year":"2009","journal-title":"Eur Urol"},{"key":"2026092423210397400_dmag027-B338","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.fertnstert.2019.06.011","article-title":"Reproductive endocrinologists are the gatekeepers for male infertility care in North America: results of a North American survey on the referral patterns and characteristics of men presenting to male infertility specialists for infertility investigations","volume":"112","author":"Samplaski","year":"2019","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B339","doi-asserted-by":"crossref","first-page":"559","DOI":"10.2164\/jandrol.111.014274","article-title":"Live birth after intrauterine insemination with spermatozoa from an oligoasthenozoospermic patient vitrified without permeable cryoprotectants","volume":"33","author":"Sanchez","year":"2012","journal-title":"J Androl"},{"key":"2026092423210397400_dmag027-B340","doi-asserted-by":"crossref","first-page":"R249","DOI":"10.1530\/REP-13-0109","article-title":"Semen analysis: update on clinical value, current needs and future perspectives","volume":"146","author":"Sanchez","year":"2013","journal-title":"Reproduction"},{"key":"2026092423210397400_dmag027-B341","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.rbmo.2018.06.023","article-title":"Sperm DNA fragmentation index as a promising predictive tool for male infertility diagnosis and treatment management - meta-analyses","volume":"37","author":"Santi","year":"2018","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B342","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1111\/j.1439-0272.2011.01267.x","article-title":"Comparison of cryopreserved human sperm from solid surface vitrification and standard vapor freezing method: on motility, morphology, vitality and DNA integrity","volume":"44","author":"Satirapod","year":"2012","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B343","doi-asserted-by":"crossref","first-page":"12293","DOI":"10.1038\/s41598-021-91636-y","article-title":"Structure-based redesigning of pentoxifylline analogs against selective phosphodiesterases to modulate sperm functional competence for assisted reproductive technologies","volume":"11","author":"Satish","year":"2021","journal-title":"Sci Rep"},{"key":"2026092423210397400_dmag027-B344","doi-asserted-by":"crossref","first-page":"279","DOI":"10.4081\/aiua.2016.4.279","article-title":"Analysis of Myo-inositol effect on spermatozoa motility, in hyper viscous ejaculates and in patients with grades II and III varicocele","volume":"88","author":"Scarselli","year":"2016","journal-title":"Arch Ital Urol Androl"},{"key":"2026092423210397400_dmag027-B345","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1111\/andr.13155","article-title":"Hyaluronic acid-sperm selection significantly improves the clinical outcome of couples with previous ICSI cycles failure","volume":"10","author":"Scaruffi","year":"2022","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B346","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1097\/JU.0000000000001521","article-title":"Diagnosis and treatment of infertility in men: AUA\/ASRM guideline Part I","volume":"205","author":"Schlegel","year":"2021","journal-title":"J Urol"},{"key":"2026092423210397400_dmag027-B347","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S1472-6483(10)61732-4","article-title":"Isolation of motile spermatozoa from semen samples using microfluidics","volume":"7","author":"Schuster","year":"2003","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B348","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1093\/humrep\/deg162","article-title":"Ultra-rapid freezing of very low numbers of sperm using cryoloops","volume":"18","author":"Schuster","year":"2003","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B349","doi-asserted-by":"crossref","first-page":"e13541","DOI":"10.1111\/and.13541","article-title":"Inclusion of ovine enriched serum with vitamin E and polyunsaturated fatty acids in the freezing medium: a new strategy to improve human frozen-thawed sperm parameters","volume":"52","author":"Seifi","year":"2020","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B350","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.cryobiol.2019.07.004","article-title":"The anti-oxidant roles of Taurine and Hypotaurine on acrosome integrity, HBA and HSPA2 of the human sperm during vitrification and post warming in two different temperature","volume":"90","author":"Seify","year":"2019","journal-title":"Cryobiology"},{"key":"2026092423210397400_dmag027-B351","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.fertnstert.2003.12.039","article-title":"Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization","volume":"82","author":"Seli","year":"2004","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B352","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S1472-6483(10)60560-3","article-title":"Freezing spermatozoa obtained by testicular fine needle aspiration: a new technique","volume":"16","author":"Sereni","year":"2008","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B353","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.fertnstert.2023.10.017","article-title":"The impact of obesity and metabolic health on male fertility: a systematic review","volume":"120","author":"Service","year":"2023","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B354","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.rbmo.2013.06.011","article-title":"Twelve years of MSOME and IMSI: a review","volume":"27","author":"Setti","year":"2013","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B355","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1016\/j.mex.2019.09.022","article-title":"Simple method of human sperm vitrification","volume":"6","author":"Shah","year":"2019","journal-title":"MethodsX"},{"key":"2026092423210397400_dmag027-B356","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.rbmo.2020.05.004","article-title":"Managing and preventing blood-borne viral infection transmission in assisted reproduction: a Canadian Fertility and Andrology Society clinical practice guideline","volume":"41","author":"Shapiro","year":"2020","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B357","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S0015-0282(02)03105-9","article-title":"Best practice policies for male infertility","volume":"77","author":"Sharlip","year":"2002","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B358","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.eururo.2016.04.010","article-title":"Cigarette smoking and semen quality: a new meta-analysis examining the effect of the 2010 world health organization laboratory methods for the examination of human semen","volume":"70","author":"Sharma","year":"2016","journal-title":"Eur Urol"},{"key":"2026092423210397400_dmag027-B359","first-page":"344","article-title":"The protective effects of alpha lipoic acid on human sperm function during freezing-thawing","volume":"41","author":"Shaygannia","year":"2020","journal-title":"Cryo Letters"},{"key":"2026092423210397400_dmag027-B360","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1093\/humrep\/dead250","article-title":"ROS-induced oxidative stress is a major contributor to sperm cryoinjury","volume":"39","author":"Shi","year":"2024","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B361","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/molehr\/4.6.555","article-title":"Prostaglandins induce calcium influx in human spermatozoa","volume":"4","author":"Shimizu","year":"1998","journal-title":"Mol Hum Reprod"},{"key":"2026092423210397400_dmag027-B362","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.fertnstert.2018.07.002","article-title":"Effects of medical comorbidity on male infertility and comorbidity treatment on spermatogenesis","volume":"110","author":"Shiraishi","year":"2018","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B363","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.fertnstert.2015.10.023","article-title":"Separation efficiency of a microfluidic sperm sorter to minimize sperm DNA damage","volume":"105","author":"Shirota","year":"2016","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B364","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s13048-024-01432-1","article-title":"Examining the oleoylethanolamide supplement effects on glycemic status, oxidative stress, inflammation, and anti-mullerian hormone in polycystic ovary syndrome","volume":"17","author":"Shivyari","year":"2024","journal-title":"J Ovarian Res"},{"key":"2026092423210397400_dmag027-B365","doi-asserted-by":"crossref","first-page":"397","DOI":"10.21037\/tau-20-1004","article-title":"Phosphatidylcholine and L-acetyl-carnitine-based freezing medium can replace egg yolk and preserves human sperm function","volume":"10","author":"Sicchieri","year":"2021","journal-title":"Transl Androl Urol"},{"key":"2026092423210397400_dmag027-B366","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.bpobgyn.2017.07.003","article-title":"Review: Diagnosis and impact of sperm DNA alterations in assisted reproduction","volume":"44","author":"Simon","year":"2017","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"2026092423210397400_dmag027-B367","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/s10815-016-0700-x","article-title":"Optimization of microelectrophoresis to select highly negatively charged sperm","volume":"33","author":"Simon","year":"2016","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B368","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/s41574-021-00598-8","article-title":"Environmental factors in declining human fertility","volume":"18","author":"Skakkeb\u00e6k","year":"2022","journal-title":"Nat Rev Endocrinol"},{"key":"2026092423210397400_dmag027-B369","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1152\/physrev.00017.2015","article-title":"Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility","volume":"96","author":"Skakkebaek","year":"2016","journal-title":"Physiol Rev"},{"key":"2026092423210397400_dmag027-B370","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1093\/humrep\/deaf179","article-title":"ART in Europe, 2020: results generated from European registries by ESHREdagger","volume":"40","author":"Smeenk","year":"2025","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B371","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1093\/biolre\/ioac224","article-title":"Sperm selection by the oviduct: perspectives for male fertility and assisted reproductive technologiesdagger","volume":"108","author":"Soto-Heras","year":"2023","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B372","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1046\/j.1365-2605.2002.00348.x","article-title":"Effect of pentoxifylline on motility and membrane integrity of cryopreserved human spermatozoa","volume":"25","author":"Stanic","year":"2002","journal-title":"Int J Androl"},{"key":"2026092423210397400_dmag027-B373","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/andr.12007","article-title":"Successful use of the Cryolock device for cryopreservation of scarce human ejaculate and testicular spermatozoa","volume":"3","author":"Stein","year":"2015","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B374","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/S0015-0282(16)54672-X","article-title":"The effects of prolactin on human sperm capacitation and acrosome reaction","volume":"56","author":"Stovall","year":"1991","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B375","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1111\/andr.12380","article-title":"Successful delivery derived from cryopreserved rare human spermatozoa with novel cryopiece","volume":"5","author":"Sun","year":"2017","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B376","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1186\/s12985-025-02833-4","article-title":"Human papillomavirus infection in males: implications for fertility, assisted reproductive outcomes, and vaccination strategies","volume":"22","author":"Sun","year":"2025","journal-title":"Virol J"},{"key":"2026092423210397400_dmag027-B377","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1111\/aogs.13449","article-title":"Men\u2019s expectations and experiences of fertility awareness assessment and counseling","volume":"97","author":"Sylvest","year":"2018","journal-title":"Acta Obstet Gynecol Scand"},{"key":"2026092423210397400_dmag027-B378","doi-asserted-by":"crossref","first-page":"105217","DOI":"10.1016\/j.rbmo.2025.105217","article-title":"Emotional experience of Danish men during fertility treatment: qualitative study on engagement, hope and loss","volume":"52","author":"Sylvest","year":"2026","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B379","doi-asserted-by":"crossref","first-page":"e13314","DOI":"10.1111\/and.13314","article-title":"Alpha-lipoic acid minimises reactive oxygen species-induced damages during sperm processing","volume":"51","author":"Taherian","year":"2019","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B380","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/1477-7827-11-81","article-title":"Protective effects of in vitro treatment with zinc, d-aspartate and coenzyme q10 on human sperm motility, lipid peroxidation and DNA fragmentation","volume":"11","author":"Talevi","year":"2013","journal-title":"Reprod Biol Endocrinol"},{"key":"2026092423210397400_dmag027-B381","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.rbmo.2018.12.029","article-title":"Association between sperm DNA fragmentation and idiopathic recurrent pregnancy loss: a systematic review and meta-analysis","volume":"38","author":"Tan","year":"2019","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B382","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12958-020-00580-5","article-title":"Human sperm vitrification: the state of the art","volume":"18","author":"Tao","year":"2020","journal-title":"Reprod Biol Endocrinol"},{"key":"2026092423210397400_dmag027-B383","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1093\/humrep\/deu196","article-title":"Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity","volume":"29","author":"Tardif","year":"2014","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B384","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s12938-021-00864-w","article-title":"Semantic segmentation of human oocyte images using deep neural networks","volume":"20","author":"Targosz","year":"2021","journal-title":"Biomed Eng Online"},{"key":"2026092423210397400_dmag027-B385","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.ejogrb.2023.05.040","article-title":"The effects of coenzyme Q10 and curcumin supplementation in freezing medium for human sperm cryopreservation","volume":"287","author":"Tas","year":"2023","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2026092423210397400_dmag027-B386","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1093\/humrep\/deaf150","article-title":"ESHRE\u2019s key research priorities in infertility: maximizing impact on science, people and societydagger","volume":"40","author":"Tassot","year":"2025","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B387","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s10815-011-9686-6","article-title":"Density gradient centrifugation before or after magnetic-activated cell sorting: which technique is more useful for clinical sperm selection?","volume":"29","author":"Tavalaee","year":"2012","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B388","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S1472-6483(10)60254-4","article-title":"Effect of antioxidant supplementation of cryopreservation medium on post-thaw integrity of human spermatozoa","volume":"18","author":"Taylor","year":"2009","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B389","first-page":"CD010167","article-title":"Regular (ICSI) versus ultra-high magnification (IMSI) sperm selection for assisted reproduction","volume":"2","author":"Teixeira","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"2026092423210397400_dmag027-B390","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/S0015-0282(16)55567-8","article-title":"Effects of phosphodiesterase inhibitors caffeine and pentoxifylline on spontaneous and stimulus-induced acrosome reactions in human sperm","volume":"58","author":"Tesarik","year":"1992","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B391","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.euf.2020.12.017","article-title":"European association of urology guidelines panel on male sexual and reproductive health: a clinical consultation guide on the indications for performing sperm DNA fragmentation testing in men with infertility and testicular sperm extraction in nonazoospermic men","volume":"8","author":"Tharakan","year":"2022","journal-title":"Eur Urol Focus"},{"key":"2026092423210397400_dmag027-B392","doi-asserted-by":"crossref","first-page":"e16064","DOI":"10.1016\/j.heliyon.2023.e16064","article-title":"Comparative study of the antioxidant capability of EDTA and Irganox","volume":"9","author":"Thbayh","year":"2023","journal-title":"Heliyon"},{"key":"2026092423210397400_dmag027-B393","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1093\/molehr\/2.10.739","article-title":"alpha-Tocopherol in human spermatozoa and seminal plasma: relationships with motility, antioxidant enzymes and leukocytes","volume":"2","author":"Therond","year":"1996","journal-title":"Mol Hum Reprod"},{"key":"2026092423210397400_dmag027-B394","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s10815-016-0656-x","article-title":"Cryopreservation of a small number of human sperm using enzymatically fabricated, hollow hyaluronan microcapsules handled by conventional ICSI procedures","volume":"33","author":"Tomita","year":"2016","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B395","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/andr.12209","article-title":"Uncertainty of measurement and clinical value of semen analysis: has standardisation through professional guidelines helped or hindered progress?","volume":"4","author":"Tomlinson","year":"2016","journal-title":"Andrology"},{"key":"2026092423210397400_dmag027-B396","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/humupd\/dmn004","article-title":"Oxidative stress and male infertility\u2014a clinical perspective","volume":"14","author":"Tremellen","year":"2008","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B397","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1093\/humrep\/dex330","article-title":"Antioxidants improve IVF outcome and subsequent embryo development in the mouse","volume":"32","author":"Truong","year":"2017","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B398","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/humrep\/dez243","article-title":"Antioxidants increase blastocyst cryosurvival and viability post-vitrification","volume":"35","author":"Truong","year":"2020","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B399","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1093\/humrep\/dew098","article-title":"Antioxidants improve mouse preimplantation embryo development and viability","volume":"31","author":"Truong","year":"2016","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B400","first-page":"12","article-title":"Disorders of spermatogenesis: perspectives for novel genetic diagnostics after 20 years of unchanged routine","volume":"30","author":"Tuttelmann","year":"2018","journal-title":"Med Genet"},{"key":"2026092423210397400_dmag027-B401","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S0015-0282(16)55568-X","article-title":"Direct effects of progesterone and antiprogesterone on human sperm hyperactivated motility and acrosome reaction","volume":"58","author":"Uhler","year":"1992","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B402","doi-asserted-by":"crossref","first-page":"e13553","DOI":"10.1111\/and.13553","article-title":"Antioxidant effects of penicillamine against in vitro-induced oxidative stress in human spermatozoa","volume":"52","author":"Uribe","year":"2020","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B403","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1126\/science.285.5432.1393","article-title":"Dual function of the selenoprotein PHGPx during sperm maturation","volume":"285","author":"Ursini","year":"1999","journal-title":"Science"},{"key":"2026092423210397400_dmag027-B404","first-page":"1059","article-title":"Iranian temporal changes in semen quality during the past 22 years: a report from an infertility center","volume":"18","author":"Vahidi","year":"2020","journal-title":"Int J Reprod Biomed"},{"key":"2026092423210397400_dmag027-B405","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1093\/humupd\/dmad006","article-title":"Contribution of semen to early embryo development: fertilization and beyond","volume":"29","author":"Vallet-Buisan","year":"2023","journal-title":"Hum Reprod Update"},{"key":"2026092423210397400_dmag027-B406","doi-asserted-by":"crossref","first-page":"e91204","DOI":"10.1172\/jci.insight.91204","article-title":"Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window","volume":"2","author":"van den Driesche","year":"2017","journal-title":"JCI Insight"},{"key":"2026092423210397400_dmag027-B407","first-page":"250","article-title":"A prediction model for ongoing pregnancy after in vitro fertilization in couples with male subfertility","volume":"53","author":"van Weert","year":"2008","journal-title":"J Reprod Med"},{"key":"2026092423210397400_dmag027-B408","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/s41378-023-00501-7","article-title":"Sperm quality metrics were improved by a biomimetic microfluidic selection platform compared to swim-up methods","volume":"9","author":"Vasilescu","year":"2023","journal-title":"Microsyst Nanoeng"},{"key":"2026092423210397400_dmag027-B409","doi-asserted-by":"crossref","first-page":"104433","DOI":"10.1016\/j.rbmo.2024.104433","article-title":"A biomimetic sperm selection device for routine sperm selection","volume":"50","author":"Vasilescu","year":"2025","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B410","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1093\/biolre\/ioz032","article-title":"Sperm selection methods in the 21st century","volume":"101","author":"Vaughan","year":"2019","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B411","first-page":"151","article-title":"Effect of vitamin E on human sperm motility and lipid peroxidation in vitro","volume":"1","author":"Verma","year":"1999","journal-title":"Asian J Androl"},{"key":"2026092423210397400_dmag027-B412","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/aja.2012.106","article-title":"Repeated vitrification\/warming of human sperm gives better results than repeated slow programmable freezing","volume":"14","author":"Vutyavanich","year":"2012","journal-title":"Asian J Androl"},{"key":"2026092423210397400_dmag027-B413","doi-asserted-by":"crossref","first-page":"5988","DOI":"10.1073\/pnas.1701425114","article-title":"Healthy offspring from freeze-dried mouse spermatozoa held on the International Space Station for 9 months","volume":"114","author":"Wakayama","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026092423210397400_dmag027-B414","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/nbt0798-639","article-title":"Development of normal mice from oocytes injected with freeze-dried spermatozoa","volume":"16","author":"Wakayama","year":"1998","journal-title":"Nat Biotechnol"},{"key":"2026092423210397400_dmag027-B415","doi-asserted-by":"crossref","first-page":"104102","DOI":"10.1016\/j.rbmo.2024.104102","article-title":"Good practice in clinical embryology laboratories: Association of Reproductive and Clinical Scientists Guidelines 2024","volume":"49","author":"Walker","year":"2024","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B416","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/humrep\/13.suppl_4.61","article-title":"The first births and ongoing pregnancies associated with sperm cryopreservation within evacuated egg zonae","volume":"13","author":"Walmsley","year":"1998","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B417","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3390\/antiox10010043","article-title":"Mechanistic insight into the regulation of lipoxygenase-driven lipid peroxidation events in human spermatozoa and their impact on male fertility","volume":"10","author":"Walters","year":"2020","journal-title":"Antioxidants (Basel)"},{"key":"2026092423210397400_dmag027-B418","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1093\/biolre\/ioy058","article-title":"Pharmacological inhibition of arachidonate 15-lipoxygenase protects human spermatozoa against oxidative stress","volume":"98","author":"Walters","year":"2018","journal-title":"Biol Reprod"},{"key":"2026092423210397400_dmag027-B419","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.rbmo.2018.08.021","article-title":"An adapted carrier for the cryopreservation of human testicular spermatozoa","volume":"37","author":"Wang","year":"2018","journal-title":"Reprod Biomed Online"},{"key":"2026092423210397400_dmag027-B420","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0015-0282(16)56228-1","article-title":"Platelet activating factor and pentoxifylline as human sperm cryoprotectants","volume":"60","author":"Wang","year":"1993","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B421","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1093\/humrep\/deac058","article-title":"Sperm selection with hyaluronic acid improved live birth outcomes among older couples and was connected to sperm DNA quality, potentially affecting all treatment outcomes","volume":"37","author":"West","year":"2022","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B422","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.ucl.2013.08.006","article-title":"The epidemiology of male infertility","volume":"41","author":"Winters","year":"2014","journal-title":"Urol Clin North Am"},{"key":"2026092423210397400_dmag027-B423","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.fertnstert.2013.03.050","article-title":"Conceiving of change: a brief intervention increases young adults\u2019 knowledge of fertility and the effectiveness of in vitro fertilization","volume":"100","author":"Wojcieszek","year":"2013","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B424","volume-title":"WHO Laboratory Manual for the Examination and Processing of Human Semen","author":"World Health Organization","year":"2021"},{"key":"2026092423210397400_dmag027-B425","volume-title":"Infertility Prevalence Estimates, 1990\u20132021","author":"World Health Organization","year":"2023"},{"key":"2026092423210397400_dmag027-B426","doi-asserted-by":"crossref","DOI":"10.2471\/B09599","volume-title":"Guideline for the Prevention, Diagnosis and Treatment of Infertility","author":"World Health Organization","year":"2025"},{"key":"2026092423210397400_dmag027-B427","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1093\/humrep\/des417","article-title":"Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes\u2014multicenter, double-blinded and randomized controlled trial","volume":"28","author":"Worrilow","year":"2013","journal-title":"Hum Reprod"},{"key":"2026092423210397400_dmag027-B428","doi-asserted-by":"crossref","first-page":"hoab026","DOI":"10.1093\/hropen\/hoab026","article-title":"ART in Europe, 2017: results generated from European registries by ESHRE","volume":"2021","author":"Wyns","year":"2021","journal-title":"Hum Reprod Open"},{"key":"2026092423210397400_dmag027-B429","doi-asserted-by":"crossref","first-page":"3084","DOI":"10.3390\/molecules24173084","article-title":"Melatonin inhibits apoptosis and oxidative stress of mouse leydig cells via a SIRT1-dependent mechanism","volume":"24","author":"Xu","year":"2019","journal-title":"Molecules"},{"key":"2026092423210397400_dmag027-B430","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1262\/jrd.2023-034","article-title":"A novel, simplified method to prepare and preserve freeze-dried mouse sperm in plastic microtubes","volume":"69","author":"Yang","year":"2023","journal-title":"J Reprod Dev"},{"key":"2026092423210397400_dmag027-B431","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1017\/S0967199424000029","article-title":"In vitro effects of the combination of serotonin, selenium, zinc, and vitamins D and E supplementation on human sperm motility and reactive oxygen species production","volume":"32","author":"Yilmazer","year":"2024","journal-title":"Zygote"},{"key":"2026092423210397400_dmag027-B432","first-page":"332","article-title":"The success rate and factors affecting the outcome of assisted reproductive treatment in subfertile men","volume":"49","author":"Zarinara","year":"2020","journal-title":"Iran J Public Health"},{"key":"2026092423210397400_dmag027-B433","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1186\/s12917-021-02804-1","article-title":"Freeze-thawing impairs the motility, plasma membrane integrity and mitochondria function of boar spermatozoa through generating excessive ROS","volume":"17","author":"Zhang","year":"2021","journal-title":"BMC Vet Res"},{"key":"2026092423210397400_dmag027-B434","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1017\/S0967199415000180","article-title":"Protective effects of l-carnitine on astheno- and normozoospermic human semen samples during cryopreservation","volume":"24","author":"Zhang","year":"2016","journal-title":"Zygote"},{"key":"2026092423210397400_dmag027-B435","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12958-024-01239-1","article-title":"Emerging trends in sperm selection: enhancing success rates in assisted reproduction","volume":"22","author":"Zhang","year":"2024","journal-title":"Reprod Biol Endocrinol"},{"key":"2026092423210397400_dmag027-B436","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s10815-014-0374-1","article-title":"Sperm DNA fragmentation index and pregnancy outcome after IVF or ICSI: a meta-analysis","volume":"32","author":"Zhang","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"2026092423210397400_dmag027-B437","doi-asserted-by":"crossref","first-page":"26334941231188656","DOI":"10.1177\/26334941231188656","article-title":"Effects of sperm processing techniques on IVF pregnancy rates: a mini-review","volume":"17","author":"Zhao","year":"2023","journal-title":"Ther Adv Reprod Health"},{"key":"2026092423210397400_dmag027-B438","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/and.12131","article-title":"Cryoprotectant-free ultra-rapid freezing of human spermatozoa in cryogenic vials","volume":"46","author":"Zhu","year":"2014","journal-title":"Andrologia"},{"key":"2026092423210397400_dmag027-B439","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.21037\/tau-20-1080","article-title":"Cryopiece, a novel carrier with faster cooling rate, high recovery rate and retrieval rate, for individual sperm cryopreservation","volume":"10","author":"Zhu","year":"2021","journal-title":"Transl Androl Urol"},{"key":"2026092423210397400_dmag027-B440","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.fertnstert.2009.04.004","article-title":"Lycopene supplementation in vitro can protect human sperm deoxyribonucleic acid from oxidative damage","volume":"94","author":"Zini","year":"2010","journal-title":"Fertil Steril"},{"key":"2026092423210397400_dmag027-B441","first-page":"915","article-title":"Acetyl-L-carnitine: an effective antioxidant against cryo-damage on human spermatozoa with asthenospermia","volume":"37","author":"Zou","year":"2017","journal-title":"J Huazhong Univ Sci Technolog Med Sci"}],"container-title":["Human Reproduction Update"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/humupd\/advance-article-pdf\/doi\/10.1093\/humupd\/dmag027\/71384160\/dmag027.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/humupd\/advance-article-pdf\/doi\/10.1093\/humupd\/dmag027\/71384160\/dmag027.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:22:07Z","timestamp":1790306527000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humupd\/advance-article\/doi\/10.1093\/humupd\/dmag027\/8834080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,24]]},"references-count":441,"URL":"https:\/\/doi.org\/10.1093\/humupd\/dmag027","relation":{},"ISSN":["1355-4786","1460-2369"],"issn-type":[{"value":"1355-4786","type":"print"},{"value":"1460-2369","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,24]]},"article-number":"dmag027"}}