{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:47:03Z","timestamp":1791298023625,"version":"4.1.0"},"reference-count":201,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3,1]]},"DOI":"10.1093\/humupd\/dmt050","type":"journal-article","created":{"date-parts":[[2013,9,29]],"date-time":"2013-09-29T22:04:30Z","timestamp":1380492270000},"page":"231-249","source":"Crossref","is-referenced-by-count":131,"title":["A critical assessment of the endocrine susceptibility of the human testis to phthalates from fetal life to adulthood"],"prefix":"10.1093","volume":"20","author":[{"given":"Oc\u00e9ane","family":"Albert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"J\u00e9gou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,9,29]]},"reference":[{"key":"key\n\t\t\t\t20171012152236_DMT050C1","first-page":"343","article-title":"Effects of di(2-ethylhexyl) phthalate on the gonadal pathophysiology, sperm morphology, and reproductive performance of male rats","volume":"65","author":"Agarwal","year":"1986","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C2","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1210\/en.2003-1174","article-title":"Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells","volume":"145","author":"Akingbemi","year":"2004","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C3","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.tice.2010.02.004","article-title":"Single administration of di(n-butyl) phthalate delays spermatogenesis in prepubertal rats","volume":"42","author":"Alam","year":"2010","journal-title":"Tissue Cell"},{"key":"key\n\t\t\t\t20171012152236_DMT050C4","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1093\/humrep\/det112","article-title":"Paracetamol, aspirin and indomethacin display endocrine disrupting properties in the adult human testis in vitro","volume":"28","author":"Albert","year":"2013","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C5","doi-asserted-by":"crossref","first-page":"127","DOI":"10.2535\/ofaj.80.127","article-title":"Effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in rats in vitro","volume":"80","author":"Andriana","year":"2004","journal-title":"Okajimas Folia Anat Jpn"},{"key":"key\n\t\t\t\t20171012152236_DMT050C6","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/S0278-6915(98)00065-9","article-title":"Oral toxicity of bis(2-ethylhexyl) phthalate during pregnancy and suckling in the Long-Evans rat","volume":"36","author":"Arcadi","year":"1998","journal-title":"Food Chem Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C7","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S0015-0282(16)48081-7","article-title":"The prostaglandin inhibitor effect of antiinflammatory drugs in the therapy of male infertility","volume":"42","author":"Barkay","year":"1984","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20171012152236_DMT050C8","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/nrurol.2011.23","article-title":"Testicular descent: INSL3, testosterone, genes and the intrauterine milieu","volume":"8","author":"Bay","year":"2011","journal-title":"Nat Rev Urol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C9","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/humrep\/16.2.236","article-title":"Effect of 4-octylphenol on germ cell number in cultured human fetal gonads","volume":"16","author":"Bendsen","year":"2001","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C10","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1365-3016.1996.tb00024.x","article-title":"Risk factors for cryptorchidism: a nested case-control study","volume":"10","author":"Berkowitz","year":"1996","journal-title":"Paediatr Perinat Epidemiol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C11","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.tox.2008.05.020","article-title":"Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats","volume":"250","author":"Boberg","year":"2008","journal-title":"Toxicology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C12","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1111\/j.1537-2995.2005.04380.x","article-title":"Transfusion-related exposure to the plasticizer di(2-ethylhexyl) phthalate in patients receiving plateletpheresis concentrates","volume":"45","author":"Buchta","year":"2005","journal-title":"Transfusion"},{"key":"key\n\t\t\t\t20171012152236_DMT050C13","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1289\/ehp.9059","article-title":"Integrating biomonitoring exposure data into the risk assessment process: phthalates [diethyl phthalate and di(2-ethylhexyl) phthalate] as a case study","volume":"114","author":"Calafat","year":"2006","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C14","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1542\/peds.113.5.e429","article-title":"Exposure to di-(2-ethylhexyl) phthalate among premature neonates in a neonatal intensive care unit","volume":"113","author":"Calafat","year":"2004","journal-title":"Pediatrics"},{"key":"key\n\t\t\t\t20171012152236_DMT050C15","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/10915810305098","article-title":"Evaluation of reproductive development following intravenous and oral exposure to DEHP in male neonatal rats","volume":"22","author":"Cammack","year":"2003","journal-title":"Int J Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C16","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1600-0668.2012.00788.x","article-title":"PVC flooring is related to human uptake of phthalates in infants","volume":"23","author":"Carlstedt","year":"2012","journal-title":"Indoor Air"},{"key":"key\n\t\t\t\t20171012152236_DMT050C17","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/0016-5085(93)90908-U","article-title":"Secretion and contribution to lipolysis of gastric and pancreatic lipases during a test meal in humans","volume":"105","author":"Carri\u00e8re","year":"1993","journal-title":"Gastroenterology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C18","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/bdrb.20050","article-title":"Critical window of male reproductive tract development in rats following gestational exposure to di-n-butyl phthalate","volume":"74","author":"Carruthers","year":"2005","journal-title":"Birth Defects Res B Dev Reprod Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C19","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/j.1439-0272.1988.tb03128.x","article-title":"Effect of aldrin on accessory sex glands and plasma testosterone levels in rats","volume":"20","author":"Chatterjee","year":"1988","journal-title":"Andrologia"},{"key":"key\n\t\t\t\t20171012152236_DMT050C20","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1289\/ehp.11870","article-title":"Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro","volume":"117","author":"Chauvign\u00e9","year":"2009","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C21","doi-asserted-by":"crossref","first-page":"e27172","DOI":"10.1371\/journal.pone.0027172","article-title":"Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis","volume":"6","author":"Chauvign\u00e9","year":"2011","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20171012152236_DMT050C22","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.tiv.2011.12.002","article-title":"In vitro metabolism of di(2-ethylhexyl) phthalate (DEHP) by various tissues and cytochrome P450s of human and rat","volume":"26","author":"Choi","year":"2012","journal-title":"Toxicol In Vitro"},{"key":"key\n\t\t\t\t20171012152236_DMT050C23","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.reprotox.2010.04.005","article-title":"Low-dose perinatal exposure to di(2-ethylhexyl) phthalate induces anti-androgenic effects in male rats","volume":"30","author":"Christiansen","year":"2010","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C24","first-page":"227","article-title":"Assessment of critical exposure pathways","volume-title":"The Handbook of Environmental Chemistry","author":"Clark","year":"2003"},{"key":"key\n\t\t\t\t20171012152236_DMT050C25","first-page":"1032","article-title":"Aspirin inhibits androgen response to chorionic gonadotropin in humans","volume":"277","author":"Conte","year":"1999","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C26","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/path.1711390307","article-title":"The morphological development of di-N-pentyl phthalate induced testicular atrophy in the rat","volume":"139","author":"Creasy","year":"1983","journal-title":"J Pathol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C27","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0014-4800(87)90056-6","article-title":"The ultrastructural effects of di-n-pentyl phthalate on the testis of the mature rat","volume":"46","author":"Creasy","year":"1987","journal-title":"Exp Mol Pathol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C28","first-page":"190","article-title":"Toxic effects of the easily avoidable phthalates and parabens","volume":"15","author":"Crinnion","year":"2010","journal-title":"Altern Med Rev"},{"key":"key\n\t\t\t\t20171012152236_DMT050C29","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1095\/biolreprod.107.065649","article-title":"In utero exposure to di-(2-ethylhexyl) phthalate exerts both short-term and long-lasting suppressive effects on testosterone production in the rat","volume":"78","author":"Culty","year":"2008","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C30","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0378-4274(01)00348-4","article-title":"The acute effects of mono(2-ethylhexyl) phthalate (MEHP) on testes of prepubertal Wistar rats","volume":"122","author":"Dalgaard","year":"2001","journal-title":"Toxicol Lett"},{"key":"key\n\t\t\t\t20171012152236_DMT050C31","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.fct.2011.11.041","article-title":"Bisphenol A impairs insulin signaling and glucose homeostasis and decreases steroidogenesis in rat testis: an in vivo and in silico study","volume":"50","author":"D'Cruz","year":"2012","journal-title":"Food Chem Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C32","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0890-6238(01)00110-1","article-title":"Effect of mono-ethylhexyl phthalate on MA-10 Leydig tumor cells","volume":"15","author":"Dees","year":"2001","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C33","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1093\/humrep\/des069","article-title":"Human testis steroidogenesis is inhibited by phthalates","volume":"27","author":"Desdoits-Lethimonier","year":"2012","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C34","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s00216-006-0669-x","article-title":"Experimental parameters affecting sensitivity and specificity of a yeast assay for estrogenic compounds: results of an interlaboratory validation exercise","volume":"386","author":"Dhooge","year":"2006","journal-title":"Anal Bioanal Chem"},{"key":"key\n\t\t\t\t20171012152236_DMT050C35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.112.106104","article-title":"Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice","volume":"88","author":"Doyle","year":"2013","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C36","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1542\/peds.2009-0724","article-title":"Plasma phthalate levels in pubertal gynecomastia","volume":"125","author":"Durmaz","year":"2010","journal-title":"Pediatrics"},{"key":"key\n\t\t\t\t20171012152236_DMT050C37","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/01.EDE.0000059950.11836.16","article-title":"Phthalate exposure and human semen parameters","volume":"14","author":"Duty","year":"2003","journal-title":"Epidemiology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C38","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1289\/ehp.8083","article-title":"Personal care product use predicts urinary concentrations of some phthalate monoesters","volume":"113","author":"Duty","year":"2005","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C39","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0890-6238(01)00111-3","article-title":"Adverse effects on development of the reproductive system in male offspring of rats given monobutyl phthalate, a metabolite of dibutyl phthalate, during late pregnancy","volume":"15","author":"Ema","year":"2001","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C40","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0378-4274(99)00192-7","article-title":"Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy","volume":"111","author":"Ema","year":"2000","journal-title":"Toxicol Lett"},{"key":"key\n\t\t\t\t20171012152236_DMT050C41","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1021\/tx030011g","article-title":"Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor","volume":"16","author":"Fang","year":"2003","journal-title":"Chem Res Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C42","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1093\/biolreprod\/9.5.500","article-title":"Comparative observations on intertubular lymphatics and the organization of the interstitial tissue of the mammalian testis","volume":"9","author":"Fawcett","year":"1973","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C43","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1177\/074823379901500801","article-title":"ATSDR evaluation of health effects of chemicals. VI. Di(2-ethylhexyl) phthalate. Agency for Toxic Substances and Disease Registry","volume":"15","author":"Fay","year":"1999","journal-title":"Toxicol Ind Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C44","doi-asserted-by":"crossref","first-page":"5352","DOI":"10.1210\/en.2006-0527","article-title":"Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation","volume":"147","author":"Ferrara","year":"2006","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C45","doi-asserted-by":"crossref","first-page":"685","DOI":"10.5603\/FHC.2011.0092","article-title":"Di(n-butyl) phthalate has no effect on the rat prepubertal testis despite its estrogenic activity in vitro","volume":"49","author":"Filipiak","year":"2011","journal-title":"Folia Histochem Cytobiol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C46","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1093\/humrep\/deg273","article-title":"Human \u2018testicular dysgenesis syndrome\u2019: a possible model using in-utero exposure of the rat to dibutyl phthalate","volume":"18","author":"Fisher","year":"2003","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C47","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1365-2605.2005.00563.x","article-title":"Disruption of reproductive development in male rat offspring following in utero exposure to phthalate esters","volume":"29","author":"Foster","year":"2006","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C48","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/0041-008X(82)90031-X","article-title":"Changes in ultrastructure and cytochemical localization of zinc in rat testis following the administration of di-n-pentyl phthalate","volume":"63","author":"Foster","year":"1982","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C49","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1093\/humupd\/7.3.231","article-title":"Effects of phthalate esters on the developing reproductive tract of male rats","volume":"7","author":"Foster","year":"2001","journal-title":"Hum Reprod Update"},{"key":"key\n\t\t\t\t20171012152236_DMT050C50","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1093\/humrep\/dem256","article-title":"Human fetal testis Leydig cell disruption by exposure to the pesticide dieldrin at low concentrations","volume":"22","author":"Fowler","year":"2007","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C51","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1002\/mnfr.200600243","article-title":"Metabolism of phthalates in humans","volume":"51","author":"Frederiksen","year":"2007","journal-title":"Mol Nutr Food Res"},{"key":"key\n\t\t\t\t20171012152236_DMT050C52","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1093\/jat\/34.7.400","article-title":"Correlations between phthalate metabolites in urine, serum, and seminal plasma from young Danish men determined by isotope dilution liquid chromatography tandem mass spectrometry","volume":"34","author":"Frederiksen","year":"2010","journal-title":"J Anal Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C53","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/j.1365-2605.2012.01260.x","article-title":"High urinary phthalate concentration associated with delayed pubarche in girls","volume":"35","author":"Frederiksen","year":"2012","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C54","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/j.envint.2007.05.006","article-title":"Intake of phthalates and di(2-ethylhexyl)adipate: results of the Integrated Exposure Assessment Survey based on duplicate diet samples and biomonitoring data","volume":"33","author":"Fromme","year":"2007","journal-title":"Environ Int"},{"key":"key\n\t\t\t\t20171012152236_DMT050C55","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1006\/taap.1996.8069","article-title":"Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay","volume":"143","author":"Gaido","year":"1997","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C56","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1093\/toxsci\/kfm049","article-title":"Fetal mouse phthalate exposure shows that gonocyte multinucleation is not associated with decreased testicular testosterone","volume":"97","author":"Gaido","year":"2007","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C57","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0278-6915(84)90092-9","article-title":"Effect of some phthalate esters and other testicular toxins on primary cultures of testicular cells","volume":"22","author":"Gray","year":"1984","journal-title":"Food Chem Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C58","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0378-4274(82)90119-9","article-title":"Species differences in the testicular toxicity of phthalate esters","volume":"11","author":"Gray","year":"1982","journal-title":"Toxicol Lett"},{"key":"key\n\t\t\t\t20171012152236_DMT050C59","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1191\/074823399678846646","article-title":"Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat","volume":"15","author":"Gray","year":"1999","journal-title":"Toxicol Ind Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C60","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1093\/toxsci\/58.2.350","article-title":"Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat","volume":"58","author":"Gray","year":"2000","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C61","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1093\/toxsci\/kfp109","article-title":"Transgenerational effects of di(2-ethylhexyl) phthalate in the male CRL:CD(SD) rat: added value of assessing multiple offspring per litter","volume":"110","author":"Gray","year":"2009","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C62","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1289\/ehp.7932","article-title":"Use of di(2-ethylhexyl) phthalate-containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infants","volume":"113","author":"Green","year":"2005","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C63","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.tox.2013.01.021","article-title":"The increased number of Leydig cells by di(2-ethylhexyl) phthalate comes from the differentiation of stem cells into Leydig cell lineage in the adult rat testis","volume":"306","author":"Guo","year":"2013","journal-title":"Toxicology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C64","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1289\/ehp.9490","article-title":"Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human","volume":"115","author":"Hallmark","year":"2007","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C65","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1080\/15287390903212972","article-title":"An exposure assessment of di-(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP) in human semen","volume":"72","author":"Han","year":"2009","journal-title":"J Toxicol Environ Health A"},{"key":"key\n\t\t\t\t20171012152236_DMT050C66","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/toxsci\/kfr146","article-title":"Dose-response assessment of fetal testosterone production and gene expression levels in rat testes following in utero exposure to diethylhexyl phthalate, diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate","volume":"123","author":"Hannas","year":"2011","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C67","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1093\/toxsci\/kfr315","article-title":"Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency","volume":"125","author":"Hannas","year":"2012","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C68","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1136\/oem.2004.017590","article-title":"Phthalates and human health","volume":"62","author":"Hauser","year":"2005","journal-title":"Occup Environ Med"},{"key":"key\n\t\t\t\t20171012152236_DMT050C69","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1097\/01.ede.0000235996.89953.d7","article-title":"Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites","volume":"17","author":"Hauser","year":"2006","journal-title":"Epidemiology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C70","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1093\/humrep\/del428","article-title":"DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites","volume":"22","author":"Hauser","year":"2007","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C71","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1289\/ehp.1104711","article-title":"Human fetal testis xenografts are resistant to phthalate-induced endocrine disruption","volume":"120","author":"Heger","year":"2012","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C72","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.ijheh.2009.08.001","article-title":"Urinary di(2-ethylhexyl) phthalate (DEHP)\u2014metabolites and male human markers of reproductive function","volume":"212","author":"Herr","year":"2009","journal-title":"Int J Hyg Environ Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C73","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.ijheh.2007.07.011","article-title":"Phthalates: toxicology and exposure","volume":"210","author":"Heudorf","year":"2007","journal-title":"Int J Hyg Environ Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C74","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/toxsci\/kfg036","article-title":"Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure","volume":"72","author":"Higuchi","year":"2003","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C75","doi-asserted-by":"crossref","first-page":"83","DOI":"10.2131\/jts.18.83","article-title":"The affinity of procymidone to androgen receptor in rats and mice","volume":"18","author":"Hosokawa","year":"1993","journal-title":"J Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C76","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.envres.2008.08.009","article-title":"Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats","volume":"108","author":"Howdeshell","year":"2008","journal-title":"Environ Res"},{"key":"key\n\t\t\t\t20171012152236_DMT050C77","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.envint.2008.05.012","article-title":"Association between prenatal exposure to phthalates and the health of newborns","volume":"35","author":"Huang","year":"2009","journal-title":"Environ Int"},{"key":"key\n\t\t\t\t20171012152236_DMT050C78","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1210\/jcem-55-5-882","article-title":"Testicular luteinizing hormone receptor content and in vitro stimulation of cyclic adenosine 3\u2032,5\u2032-monophosphate and steroid production: a comparison between man and rat","volume":"55","author":"Huhtaniemi","year":"1982","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20171012152236_DMT050C79","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1002\/etc.1912","article-title":"An interlaboratory comparison study for the determination of dialkyl phthalate esters in environmental and biological samples","volume":"31","author":"Ikonomou","year":"2012","journal-title":"Environ Toxicol Chem"},{"key":"key\n\t\t\t\t20171012152236_DMT050C80","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s003830000474","article-title":"The biological effect of phthalate esters on transabdominal migration of the testis in fetal rats in comparison with the antiandrogen flutamide","volume":"17","author":"Imajima","year":"2001","journal-title":"Pediatr Surg Int"},{"key":"key\n\t\t\t\t20171012152236_DMT050C81","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/MED.0b013e3283453fe6","article-title":"Biological role and clinical significance of insulin-like peptide 3","volume":"18","author":"Ivell","year":"2011","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"key\n\t\t\t\t20171012152236_DMT050C82","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.1365-2605.2007.00841.x","article-title":"Urinary excretion of phthalates and paraben after repeated whole-body topical application in humans","volume":"31","author":"Janjua","year":"2008","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C83","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.tox.2007.01.018","article-title":"Study on developmental abnormalities in hypospadiac male rats induced by maternal exposure to di-n-butyl phthalate (DBP)","volume":"232","author":"Jiang","year":"2007","journal-title":"Toxicology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C84","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1289\/ehp.1205113","article-title":"Phthalate excretion pattern and testicular function: a study of 881 healthy Danish men","volume":"120","author":"Joensen","year":"2012","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C85","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1093\/toxsci\/kfr020","article-title":"Species-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathways","volume":"120","author":"Johnson","year":"2011","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C86","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/toxsci\/kfs206","article-title":"Of mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent","volume":"129","author":"Johnson","year":"2012","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C87","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1097\/01.ede.0000164555.19041.01","article-title":"Urinary phthalate metabolites and biomarkers of reproductive function in young men","volume":"16","author":"J\u00f6nsson","year":"2005","journal-title":"Epidemiology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C88","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1093\/jat\/27.5.284","article-title":"Quantitative detection of nine phthalate metabolites in human serum using reversed-phase high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry","volume":"27","author":"Kato","year":"2003","journal-title":"J Anal Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C89","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.reprotox.2006.04.007","article-title":"NTP-CERHR Expert Panel update on the reproductive and developmental toxicity of di(2-ethylhexyl) phthalate","volume":"22","author":"Kavlock","year":"2006","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C90","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1006\/taap.1994.1117","article-title":"Environmental hormone disruptors: evidence that vinclozolin developmental toxicity is mediated by antiandrogenic metabolites","volume":"126","author":"Kelce","year":"1994","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C91","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/375581a0","article-title":"Persistent DDT metabolite p,p\u2032-DDE is a potent androgen receptor antagonist","volume":"375","author":"Kelce","year":"1995","journal-title":"Nature"},{"key":"key\n\t\t\t\t20171012152236_DMT050C92","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1006\/taap.1996.7966","article-title":"Vinclozolin and p,p\u2032-DDE alter androgen-dependent gene expression: in vivo confirmation of an androgen receptor-mediated mechanism","volume":"142","author":"Kelce","year":"1997","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C93","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.taap.2012.08.009","article-title":"Kinetics of di(2-ethylhexyl) phthalate (DEHP) and mono(2-ethylhexyl) phthalate in blood and of DEHP metabolites in urine of male volunteers after single ingestion of ring-deuterated DEHP","volume":"264","author":"Kessler","year":"2012","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C94","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1289\/ehp.0901065","article-title":"Diastereomers of the brominated flame retardant 1,2-dibromo-4-(1,2 dibromoethyl)cyclohexane induce androgen receptor activation in the hepg2 hepatocellular carcinoma cell line and the lncap prostate cancer cell line","volume":"117","author":"Khalaf","year":"2009","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C95","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1080\/15287390490514859","article-title":"Neonatal exposure to di(n-butyl) phthalate (DBP) alters male reproductive-tract development","volume":"67","author":"Kim","year":"2004","journal-title":"J Toxicol Environ Health A"},{"key":"key\n\t\t\t\t20171012152236_DMT050C96","doi-asserted-by":"crossref","first-page":"e2011008","DOI":"10.5620\/eht.2011.26.e2011008","article-title":"Health risks assessment in children for phthalate exposure associated with childcare facilities and indoor playgrounds","volume":"26","author":"Kim","year":"2011","journal-title":"Environ Health Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C97","doi-asserted-by":"crossref","DOI":"10.1262\/jrd.2012-180","article-title":"Effects on the local immunity in the testis by exposure to di-(2-ethylhexyl) phthalate (DEHP) in mice","author":"Kitaoka","year":"2013","journal-title":"J Reprod Dev"},{"key":"key\n\t\t\t\t20171012152236_DMT050C98","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1530\/REP-12-0266","article-title":"Novel molecular targets associated with testicular dysgenesis induced by gestational exposure to diethylhexyl phthalate in the rat: a role for estradiol","volume":"144","author":"Klinefelter","year":"2013","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20171012152236_DMT050C99","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.rbmo.2013.02.005","article-title":"Endocrine-disrupting chemicals and male reproductive health","volume":"26","author":"Knez","year":"2013","journal-title":"Reprod Biomed Online"},{"key":"key\n\t\t\t\t20171012152236_DMT050C100","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1098\/rstb.2008.0208","article-title":"Human body burdens of chemicals used in plastic manufacture","volume":"364","author":"Koch","year":"2009","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C101","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1078\/1438-4639-00205","article-title":"An estimation of the daily intake of di(2-ethylhexyl) phthalate (DEHP) and other phthalates in the general population","volume":"206","author":"Koch","year":"2003","journal-title":"Int J Hyg Environ Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C102","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.ijheh.2005.07.001","article-title":"Di(2-ethylhexyl) phthalate (DEHP) exposure of voluntary plasma and platelet donors","volume":"208","author":"Koch","year":"2005","journal-title":"Int J Hyg Environ Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C103","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s00204-004-0642-4","article-title":"New metabolites of di(2-ethylhexyl) phthalate (DEHP) in human urine and serum after single oral doses of deuterium-labelled DEHP","volume":"79","author":"Koch","year":"2005","journal-title":"Arch Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C104","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s00204-005-0004-x","article-title":"Intravenous exposure to di(2-ethylhexyl) phthalate (DEHP): metabolites of DEHP in urine after a voluntary platelet donation","volume":"79","author":"Koch","year":"2005","journal-title":"Arch Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C105","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s00420-004-0570-x","article-title":"Exposure of nursery school children and their parents and teachers to di-n-butylphthalate and butylbenzylphthalate","volume":"78","author":"Koch","year":"2005","journal-title":"Int Arch Occup Environ Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C106","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2012.12.002","article-title":"Identifying sources of phthalate exposure with human biomonitoring: results of a 48 h fasting study with urine collection and personal activity patterns","author":"Koch","year":"2013","journal-title":"Int J Hyg Environ Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C107","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/j.jpedsurg.2006.03.009","article-title":"Age-specific effect of phthalate ester on testicular development in rats","volume":"41","author":"Kondo","year":"2006","journal-title":"J Pediatr Surg"},{"key":"key\n\t\t\t\t20171012152236_DMT050C108","first-page":"E14","article-title":"A scientific evaluation of health effects of two plasticizers used in medical devices and toys: a report from the American Council on Science and Health","author":"Koop","year":"1999","journal-title":"MedGenMed"},{"key":"key\n\t\t\t\t20171012152236_DMT050C109","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1365-2605.2012.01282.x","article-title":"Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis","volume":"35","author":"Kristensen","year":"2012","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C110","first-page":"49","article-title":"Subchronic toxicity of di(2-ethylhexyl) phthalate in common marmosets: lack of hepatic peroxisome proliferation, testicular atrophy, or pancreatic acinar cell hyperplasia","volume":"42","author":"Kurata","year":"1998","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C111","doi-asserted-by":"crossref","first-page":"33","DOI":"10.2131\/jts.37.33","article-title":"Metabolism of di (2-ethylhexyl) phthalate (DEHP): comparative study in juvenile and fetal marmosets and rats","volume":"37","author":"Kurata","year":"2012","journal-title":"J Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C112","doi-asserted-by":"crossref","first-page":"4688","DOI":"10.1210\/en.2008-0310","article-title":"Antagonistic effects of testosterone and the endocrine disruptor mono-(2-ethylhexyl) phthalate on INSL3 transcription in Leydig cells","volume":"149","author":"Lague","year":"2008","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C113","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0300-483X(76)90038-X","article-title":"Studies on the effects of orally administered di-(2-ethylhexyl) phthalate in the ferret","volume":"6","author":"Lake","year":"1976","journal-title":"Toxicology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C114","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1093\/toxsci\/56.2.389","article-title":"Cellular and molecular mechanisms of action of linuron: an antiandrogenic herbicide that produces reproductive malformations in male rats","volume":"56","author":"Lambright","year":"2000","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C115","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1289\/ehp.11146","article-title":"Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production","volume":"117","author":"Lambrot","year":"2009","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C116","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1093\/toxsci\/kfg065","article-title":"Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture","volume":"73","author":"Lassurguere","year":"2003","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C117","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1289\/ehp.6202","article-title":"In utero exposure to di-(2-ethylhexyl) phthalate and duration of human pregnancy","volume":"111","author":"Latini","year":"2003","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C118","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1093\/toxsci\/kfi087","article-title":"Subchronic exposure to low concentrations of di-n-butyl phthalate disrupts spermatogenesis in Xenopus laevis frogs","volume":"84","author":"Lee","year":"2005","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C119","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1093\/toxsci\/kfg150","article-title":"Antiandrogenic effects of bisphenol A and nonylphenol on the function of androgen receptor","volume":"75","author":"Lee","year":"2003","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C120","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1093\/toxsci\/kfp153","article-title":"Phthalates impair germ cell number in the mouse fetal testis by an androgen- and estrogen-independent mechanism","volume":"111","author":"Lehraiki","year":"2009","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C121","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1095\/biolreprod.103.018895","article-title":"Effects of mono-(2-ethylhexyl) phthalate on fetal and neonatal rat testis organ cultures","volume":"69","author":"Li","year":"2003","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C122","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1006\/taap.1998.8550","article-title":"Effects of relatively low levels of mono-(2-ethylhexyl) phthalate on cocultured Sertoli cells and gonocytes from neonatal rats","volume":"153","author":"Li","year":"1998","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C123","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1006\/taap.2000.8972","article-title":"A single dose of di-(2-ethylhexyl) phthalate in neonatal rats alters gonocytes, reduces Sertoli cell proliferation, and decreases cyclin D2 expression","volume":"166","author":"Li","year":"2000","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C124","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1095\/biolreprod.104.039404","article-title":"Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis","volume":"73","author":"Liu","year":"2005","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C125","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1053\/jpsu.2000.19249","article-title":"Polyvinylchloride infusion lines expose infants to large amounts of toxic plasticizers","volume":"35","author":"Loff","year":"2000","journal-title":"J Pediatr Surg"},{"key":"key\n\t\t\t\t20171012152236_DMT050C126","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.tox.2012.04.011","article-title":"Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia","volume":"299","author":"Lucas","year":"2012","journal-title":"Toxicology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C127","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1365-2605.2009.01005.x","article-title":"Androgen action in the masculinization programming window and development of male reproductive organs","volume":"33","author":"Macleod","year":"2010","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C128","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1289\/ehp.8075","article-title":"Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age","volume":"114","author":"Main","year":"2006","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C129","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1210\/endo.137.3.8603575","article-title":"Expression of cytochrome P450 17alpha-hydroxylase\/C17\u201320 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens","volume":"137","author":"Majdic","year":"1996","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C130","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1006\/taap.1998.8431","article-title":"Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells","volume":"151","author":"Maness","year":"1998","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C131","doi-asserted-by":"crossref","first-page":"e55387","DOI":"10.1371\/journal.pone.0055387","article-title":"Plastics derived endocrine disruptors (BPA, DEHP and DBP) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations","volume":"8","author":"Manikkam","year":"2013","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20171012152236_DMT050C132","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.toxlet.2012.11.025","article-title":"Biological impact of phthalates","volume":"217","author":"Mankidy","year":"2013","journal-title":"Toxicol Lett"},{"key":"key\n\t\t\t\t20171012152236_DMT050C133","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1095\/biolreprod.110.089920","article-title":"In utero exposure to the antiandrogen di-(2-ethylhexyl) phthalate decreases adrenal aldosterone production in the adult rat","volume":"85","author":"Martinez-Arguelles","year":"2011","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C134","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsbmb.2013.01.007","article-title":"Fetal origin of endocrine dysfunction in the adult: the phthalate model","author":"Martinez-Arguelles","year":"2013","journal-title":"J Steroid Biochem Mol Biol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C135","doi-asserted-by":"crossref","DOI":"10.1210\/jc.2013-2531","article-title":"Paracetamol, aspirin and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent","author":"Mazaud-Guittot","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20171012152236_DMT050C136","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.reprotox.2003.09.002","article-title":"NTP center for the evaluation of risks to human reproduction reports on phthalates: addressing the data gaps","volume":"18","author":"McKee","year":"2004","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C137","doi-asserted-by":"crossref","first-page":"4536","DOI":"10.1210\/en.2005-0676","article-title":"Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-butyl) phthalate","volume":"146","author":"McKinnell","year":"2005","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C138","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1093\/humrep\/dep200","article-title":"Effect of fetal or neonatal exposure to monobutyl phthalate (MBP) on testicular development and function in the marmoset","volume":"24","author":"McKinnell","year":"2009","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C139","doi-asserted-by":"crossref","first-page":"287","DOI":"10.2164\/jandrol.108.006403","article-title":"Urinary metabolites of di(2-ethylhexyl) phthalate are associated with decreased steroid hormone levels in adult men","volume":"30","author":"Meeker","year":"2009","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C140","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1365-2605.2010.01095.x","article-title":"Associations between urinary metabolites of di(2-ethylhexyl) phthalate and reproductive hormones in fertile men","volume":"34","author":"Mendiola","year":"2011","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C141","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1365-2605.2012.01279.x","article-title":"Urinary phthalate excretion in 555 healthy Danish boys with and without pubertal gynaecomastia","volume":"35","author":"Mieritz","year":"2012","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C201","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1093\/humrep\/deq183","volume":"25","author":"Mitchell","year":"2010","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C142","doi-asserted-by":"crossref","first-page":"E341","DOI":"10.1210\/jc.2011-2411","article-title":"Do phthalates affect steroidogenesis by the human fetal testis? Exposure of human fetal testis xenografts to di-n-butyl phthalate","volume":"97","author":"Mitchell","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20171012152236_DMT050C143","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1080\/01926230701481931","article-title":"Dose-dependent effects of Sertoli cell toxicants 2,5-hexanedione, carbendazim, and mono-(2-ethylhexyl) phthalate in adult rat testis","volume":"35","author":"Moffit","year":"2007","journal-title":"Toxicol Pathol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C144","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1177\/074823379901500107","article-title":"Peripubertal exposure to the antiandrogenic fungicide, vinclozolin, delays puberty, inhibits the development of androgen-dependent tissues, and alters androgen receptor function in the male rat","volume":"15","author":"Monosson","year":"1999","journal-title":"Toxicol Ind Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C145","doi-asserted-by":"crossref","DOI":"10.1210\/en.2012-2227","article-title":"Prepubertal mouse testis growth and maturation and androgen production are acutely sensitive to di-n-butyl phthalate","author":"Moody","year":"2013","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C146","doi-asserted-by":"crossref","DOI":"10.1210\/jc.2013-1284","article-title":"Urinary phthalates from 168 girls and boys measured twice a year during a 5 year period: associations with adrenal androgen levels and puberty","author":"Mouritsen","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20171012152236_DMT050C147","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.taap.2012.03.016","article-title":"Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: in vitro and in vivo approaches","volume":"261","author":"Muczynski","year":"2012","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C148","doi-asserted-by":"crossref","first-page":"e48266","DOI":"10.1371\/journal.pone.0048266","article-title":"Cellular and molecular effect of MEHP Involving LXR\u03b1 in human fetal testis and ovary","volume":"7","author":"Muczynski","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20171012152236_DMT050C149","first-page":"15","article-title":"Report: Human exposure to selected phthalates in Denmark by the Danish Veterinary and Food Administration","author":"M\u00fcller","year":"2003","journal-title":"FodevareRapport"},{"key":"key\n\t\t\t\t20171012152236_DMT050C150","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/toxsci\/43.1.47","article-title":"Male reproductive tract malformations in rats following gestational and lactational exposure to di(n-butyl) phthalate: an antiandrogenic mechanism?","volume":"43","author":"Mylchreest","year":"1998","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C151","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0890-6238(01)00201-5","article-title":"Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate","volume":"16","author":"Mylchreest","year":"2002","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C152","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0300-483X(80)90053-0","article-title":"Testicular atrophy induced by phthalic acid monoesters: effects of zinc and testosterone concentrations","volume":"15","author":"Oishi","year":"1980","journal-title":"Toxicology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C153","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.ecoenv.2011.09.004","article-title":"Circulating levels of bisphenol A (BPA) and phthalates in an elderly population in Sweden, based on the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS)","volume":"75","author":"Olsen","year":"2012","journal-title":"Ecotoxicol Environ Saf"},{"key":"key\n\t\t\t\t20171012152236_DMT050C154","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1289\/ehp.11933","article-title":"Endocrine disruptors in the workplace, hair spray, folate supplementation, and risk of hypospadias: case-control study","volume":"117","author":"Ormond","year":"2009","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C155","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1177\/074823379901500108","article-title":"The fungicide procymidone alters sexual differentiation in the male rat by acting as an androgen-receptor antagonist in vivo and in vitro","volume":"15","author":"Ostby","year":"1999","journal-title":"Toxicol Ind Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C156","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.cell.2011.02.004","article-title":"Endocrine regulation of male fertility by the skeleton","volume":"144","author":"Oury","year":"2011","journal-title":"Cell"},{"key":"key\n\t\t\t\t20171012152236_DMT050C157","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1289\/ehp.9016","article-title":"Decreased serum free testosterone in workers exposed to high levels of di-n-butyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP): a cross-sectional study in China","volume":"114","author":"Pan","year":"2006","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C158","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1177\/0960327110374205","article-title":"Environmental and experimental exposure of phthalate esters: the toxicological consequence on human sperm","volume":"30","author":"Pant","year":"2011","journal-title":"Hum Exp Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C159","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1093\/toxsci\/58.2.339","article-title":"The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat","volume":"58","author":"Parks","year":"2000","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C160","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1001\/archinte.1982.00340250097015","article-title":"Ketoconazole blocks testosterone synthesis","volume":"142","author":"Pont","year":"1982","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t20171012152236_DMT050C161","first-page":"299","article-title":"Comparative pharmacokinetics and subacute toxicity of di(2-ethylhexyl) phthalate (DEHP) in rats and marmosets: extrapolation of effects in rodents to man","volume":"65","author":"Rhodes","year":"1986","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C162","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1006\/taap.1996.0055","article-title":"Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes","volume":"137","author":"Richburg","year":"1996","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C163","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1365-2605.2005.00567.x","article-title":"Human exposure to phthalates via consumer products","volume":"29","author":"Schettler","year":"2006","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C164","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1210\/en.2006-1622","article-title":"Role of androgens in fetal testis development and dysgenesis","volume":"148","author":"Scott","year":"2007","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20171012152236_DMT050C165","volume-title":"The Technology of Plasticizers","author":"Sears","year":"1982"},{"key":"key\n\t\t\t\t20171012152236_DMT050C166","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1046\/j.1464-410x.2000.00710.x","article-title":"Time-specific effects of mono-n-butyl phthalate on the transabdominal descent of the testis in rat fetuses","volume":"86","author":"Shono","year":"2000","journal-title":"BJU Int"},{"key":"key\n\t\t\t\t20171012152236_DMT050C167","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/toxsci\/64.2.233","article-title":"Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate","volume":"64","author":"Shultz","year":"2001","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C168","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1289\/ehp.6723","article-title":"Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999\u20132000","volume":"112","author":"Silva","year":"2004","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C169","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/BF01688260","article-title":"Reversibility of the inhibitory effect of atrazine and lindane on cytosol 5 alpha-dihydrotestosterone receptor complex formation in rat prostate","volume":"46","author":"Simi\u0107","year":"1991","journal-title":"Bull Environ Contam Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C170","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1365-2605.2011.01240.x","article-title":"Cumulative risk assessment of phthalate exposure of Danish children and adolescents using the hazard index approach","volume":"35","author":"Soeborg","year":"2012","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C171","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1177\/147323000803600316","article-title":"Effects of diethylhexyl phthalate (DEHP) on INSL3 mRNA expression by Leydig cells derived from mouse embryos and in newborn mice","volume":"36","author":"Song","year":"2008","journal-title":"J Int Med Res"},{"key":"key\n\t\t\t\t20171012152236_DMT050C172","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.taap.2005.05.010","article-title":"In vivo and in vitro anti-androgenic effects of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture","volume":"207","author":"Stoker","year":"2005","journal-title":"Toxicol Appl Pharmacol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C173","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1677\/JOE-06-0004","article-title":"Stimulation of the pituitary-adrenal axis and of adrenocortical steroidogenesis ex vivo by administration of di-2-ethylhexyl phthalate to prepubertal male rats","volume":"192","author":"Supornsilchai","year":"2007","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C174","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1365-2605.2011.01190.x","article-title":"Foetal exposure to phthalate esters and anogenital distance in male newborns","volume":"35","author":"Suzuki","year":"2012","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20171012152236_DMT050C175","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.reprotox.2008.05.057","article-title":"Inhibitory effects of mono-ethylhexyl phthalate on steroidogenesis in immature and adult rat Leydig cells in vitro","volume":"25","author":"Svechnikov","year":"2008","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C176","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.envres.2008.08.007","article-title":"Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans","volume":"108","author":"Swan","year":"2008","journal-title":"Environ Res"},{"key":"key\n\t\t\t\t20171012152236_DMT050C177","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1289\/ehp.8100","article-title":"Decrease in anogenital distance among male infants with prenatal phthalate exposure","volume":"113","author":"Swan","year":"2005","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C178","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jchromb.2004.01.056","article-title":"Determination of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in human serum using liquid chromatography-tandem mass spectrometry","volume":"804","author":"Takatori","year":"2004","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C179","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2535\/ofaj.83.123","article-title":"An ultrastructural study on the effects of mono(2-ethylhexyl) phthalate on mice testes: cell death and sloughing of spermatogenic cells","volume":"83","author":"Tay","year":"2007","journal-title":"Okajimas Folia Anat Jpn"},{"key":"key\n\t\t\t\t20171012152236_DMT050C180","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3109\/10408448409023761","article-title":"Biological effects of di-(2-ethylhexyl) phthalate and other phthalic acid esters","volume":"13","author":"Thomas","year":"1984","journal-title":"Crit Rev Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C181","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/BF00405615","article-title":"Occupational exposure to hexachlorocyclohexane. IV. Sex hormone alterations in HCH-exposed workers","volume":"48","author":"Tomczak","year":"1981","journal-title":"Int Arch Occup Environ Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C182","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1080\/15287390600630054","article-title":"Effect of di(2-ethylhexyl) phthalate (DEHP) on genital organs from juvenile common marmosets: I. Morphological and biochemical investigation in 65-week toxicity study","volume":"69","author":"Tomonari","year":"2006","journal-title":"J Toxicol Environ Health A"},{"key":"key\n\t\t\t\t20171012152236_DMT050C183","doi-asserted-by":"crossref","first-page":"e30111","DOI":"10.1371\/journal.pone.0030111","article-title":"Inter-relationship between testicular dysgenesis and Leydig cell function in the masculinization programming window in the rat","volume":"7","author":"van den Driesche","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20171012152236_DMT050C184","doi-asserted-by":"crossref","first-page":"e37064","DOI":"10.1371\/journal.pone.0037064","article-title":"Proposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents","volume":"7","author":"van den Driesche","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20171012152236_DMT050C185","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1093\/toxsci\/69.2.344","article-title":"Antiandrogenic effects in vitro and in vivo of the fungicide prochloraz","volume":"69","author":"Vinggaard","year":"2002","journal-title":"Toxicol Sci"},{"key":"key\n\t\t\t\t20171012152236_DMT050C186","doi-asserted-by":"crossref","first-page":"e56800","DOI":"10.1371\/journal.pone.0056800","article-title":"Urinary phthalate metabolites are associated with body mass index and waist circumference in Chinese school children","volume":"8","author":"Wang","year":"2013","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20171012152236_DMT050C187","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1172\/JCI34241","article-title":"Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism","volume":"118","author":"Welsh","year":"2008","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20171012152236_DMT050C188","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1289\/ehp.8926","article-title":"Exposure to phthalates in neonatal intensive care unit infants: urinary concentrations of monoesters and oxidative metabolites","volume":"114","author":"Weuve","year":"2006","journal-title":"Environ Health Perspect"},{"key":"key\n\t\t\t\t20171012152236_DMT050C189","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1021\/jf60201a047","article-title":"The retention, distribution, excretion, and metabolism of dibutyl phthalate-7\u201314 C in the rat","volume":"23","author":"Williams","year":"1975","journal-title":"J Agric Food Chem"},{"key":"key\n\t\t\t\t20171012152236_DMT050C190","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1210\/edrv.20.5.0377","article-title":"The role of androgens in male gender role behavior","volume":"20","author":"Wilson","year":"1999","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20171012152236_DMT050C191","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.toxlet.2003.09.012","article-title":"Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis","volume":"146","author":"Wilson","year":"2004","journal-title":"Toxicol Lett"},{"key":"key\n\t\t\t\t20171012152236_DMT050C192","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.toxlet.2007.03.004","article-title":"Differential expression of the phthalate syndrome in male Sprague-Dawley and Wistar rats after in utero DEHP exposure","volume":"170","author":"Wilson","year":"2007","journal-title":"Toxicol Lett"},{"key":"key\n\t\t\t\t20171012152236_DMT050C193","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1080\/19396360802055921","article-title":"A pilot study associating urinary concentrations of phthalate metabolites and semen quality","volume":"54","author":"Wirth","year":"2008","journal-title":"Syst Biol Reprod Med"},{"key":"key\n\t\t\t\t20171012152236_DMT050C194","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.ijheh.2007.01.037","article-title":"Internal phthalate exposure over the last two decades\u2014a retrospective human biomonitoring study","volume":"210","author":"Wittassek","year":"2007","journal-title":"Int J Hyg Environ Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C195","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/mnfr.201000121","article-title":"Assessing exposure to phthalates \u2013 the human biomonitoring approach","volume":"55","author":"Wittassek","year":"2011","journal-title":"Mol Nutr Food Res"},{"key":"key\n\t\t\t\t20171012152236_DMT050C196","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1177\/074823379901500109","article-title":"Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p\u2019-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat","volume":"15","author":"Wolf","year":"1999","journal-title":"Toxicol Ind Health"},{"key":"key\n\t\t\t\t20171012152236_DMT050C197","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1111\/j.1539-6924.2006.00770.x","article-title":"What are the sources of exposure to eight frequently used phthalic acid esters in Europeans?","volume":"26","author":"Wormuth","year":"2006","journal-title":"Risk Anal"},{"key":"key\n\t\t\t\t20171012152236_DMT050C198","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1177\/1091581809355488","article-title":"Dynamic effect of di-2-(ethylhexyl) phthalate on testicular toxicity: epigenetic changes and their impact on gene expression","volume":"29","author":"Wu","year":"2010","journal-title":"Int J Toxicol"},{"key":"key\n\t\t\t\t20171012152236_DMT050C199","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1095\/biolreprod.108.073122","article-title":"TNF alpha-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2","volume":"80","author":"Yao","year":"2009","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20171012152236_DMT050C200","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.cbi.2011.12.008","article-title":"Effects of phthalates on 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 activities in human and rat testes","volume":"195","author":"Yuan","year":"2012","journal-title":"Chem Biol Interact"}],"container-title":["Human Reproduction Update"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humupd\/article-pdf\/20\/2\/231\/1916445\/dmt050.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T18:19:41Z","timestamp":1564165181000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/humupd\/article\/20\/2\/231\/664157\/A-critical-assessment-of-the-endocrine"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,29]]},"references-count":201,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,9,29]]},"published-print":{"date-parts":[[2014,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/humupd\/dmt050","relation":{},"ISSN":["1460-2369","1355-4786"],"issn-type":[{"value":"1460-2369","type":"electronic"},{"value":"1355-4786","type":"print"}],"subject":[],"published-other":{"date-parts":[[2014,3]]},"published":{"date-parts":[[2013,9,29]]}}}