{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:05:40Z","timestamp":1793221540280,"version":"4.5.0"},"reference-count":181,"publisher":"Oxford University Press (OUP)","issue":"5","funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes for Health Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum. Reprod. Update"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1093\/humupd\/dmw015","type":"journal-article","created":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T04:47:04Z","timestamp":1466052424000},"page":"574-587","source":"Crossref","is-referenced-by-count":308,"title":["The human epididymis: its function in sperm maturation"],"prefix":"10.1093","volume":"22","author":[{"given":"Robert","family":"Sullivan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Mieusset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,6,15]]},"reference":[{"key":"2016082823222362000_22.5.574.1","unstructured":"Aitken R , Hinton BT , Orgebin-Crist MC . Male contraception. A choice on the horizon. New York: Elsevier, 2004."},{"key":"2016082823222362000_22.5.574.2","doi-asserted-by":"publisher","DOI":"10.1126\/science.182.4115.946"},{"key":"2016082823222362000_22.5.574.3","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1071\/BI9820469","article-title":"Possible mechanisms of vasectomy-exacerbated atherosclerosis","volume":"35","author":"Alexander","year":"1982","journal-title":"Aust J Biol Sci"},{"key":"2016082823222362000_22.5.574.4","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.1981.tb00595.x"},{"key":"2016082823222362000_22.5.574.5","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.107.004655"},{"key":"2016082823222362000_22.5.574.6","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0022-5347(17)55377-X","article-title":"Daily spermatozoal production and epididymal spermatozoal reserves of the human male","volume":"124","author":"Amann","year":"1980","journal-title":"J Urol"},{"key":"2016082823222362000_22.5.574.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2009.05.005"},{"key":"2016082823222362000_22.5.574.8","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00441-004-0902-x","article-title":"Regulation of the initial segment of the murine epididymis by dihydrotestosterone and testicular exocrine secretions studied by expression of specific proteins and gene expression","volume":"317","author":"Avram","year":"2004","journal-title":"Cell Tissue Res"},{"key":"2016082823222362000_22.5.574.9","doi-asserted-by":"publisher","DOI":"10.1021\/pr200812p"},{"key":"2016082823222362000_22.5.574.10","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1401660210"},{"key":"2016082823222362000_22.5.574.11","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod14.2.118"},{"key":"2016082823222362000_22.5.574.12","unstructured":"Bedford J . Evolution of the sperm maturation and sperm storage functions in the epididymis. In: Fawcett DW , Bedford J (ed). The spermatozoa. Baltimore: Urban & Schwarzenberg, 1979, 7\u201321."},{"key":"2016082823222362000_22.5.574.13","unstructured":"Bedford J . Models for investigation of gamete function in the male and female reproductive tracts. In: Serio M , Martini L. (eds). Animal models in human reproduction. New York: Raven press, 1980, 233\u2013248."},{"key":"2016082823222362000_22.5.574.14","unstructured":"Bedford J . Sperm dynamics in the epididymis. In: Asch R , Balmaceda JP , Johnson I. (ed). Gamete physiology Serono symposium . Norwell, MA, USA, 1990, 53."},{"key":"2016082823222362000_22.5.574.15","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/"},{"key":"2016082823222362000_22.5.574.16","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.115.130484"},{"key":"2016082823222362000_22.5.574.17","first-page":"199","article-title":"The maturation of spermatozoa in the human epididymis","volume":"18","author":"Bedford","year":"1973","journal-title":"J Reprod Fertil Suppl"},{"key":"2016082823222362000_22.5.574.18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034996"},{"key":"2016082823222362000_22.5.574.19","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/det088"},{"key":"2016082823222362000_22.5.574.20","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-012-1381-0"},{"key":"2016082823222362000_22.5.574.21","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod63.4.1172"},{"key":"2016082823222362000_22.5.574.22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1988.tb22266.x"},{"key":"2016082823222362000_22.5.574.23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0854.2011.01225.x"},{"key":"2016082823222362000_22.5.574.24","first-page":"112","article-title":"Does the decrease in sperm P34H correlates with the time elapsed between vasectomy and vasovasostomy","volume":"30","author":"Boudreau","year":"2009","journal-title":"J Androl"},{"key":"2016082823222362000_22.5.574.25","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod51.4.577"},{"key":"2016082823222362000_22.5.574.26","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod54.5.1009"},{"key":"2016082823222362000_22.5.574.27","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod52.2.267"},{"key":"2016082823222362000_22.5.574.28","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod54.5.1018"},{"key":"2016082823222362000_22.5.574.29","doi-asserted-by":"publisher","DOI":"10.1111\/j.0021-8782.2004.00272.x"},{"key":"2016082823222362000_22.5.574.30","first-page":"999","article-title":"Does vasectomy increase the risk of atherosclerosis","volume":"5","author":"Clarkson","year":"1980","journal-title":"J Cardiovasc Med"},{"key":"2016082823222362000_22.5.574.31","doi-asserted-by":"publisher","DOI":"10.1042\/bj20020869"},{"key":"2016082823222362000_22.5.574.32","doi-asserted-by":"crossref","unstructured":"Cooper TG . The epididymis, sperm maturation and fertilisation. New York: Springer, 1986.","DOI":"10.1007\/978-3-642-71471-9"},{"key":"2016082823222362000_22.5.574.33","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)53988-0"},{"key":"2016082823222362000_22.5.574.34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.1993.tb01187.x"},{"key":"2016082823222362000_22.5.574.35","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.103.017566"},{"key":"2016082823222362000_22.5.574.36","doi-asserted-by":"crossref","unstructured":"Cooper TG , Yeung C-H . Sperm maturaiton in the human epididymis. In: De Jonge C , Barratt C. (ed). The Sperm Cell Production, Maturation, Fertilization, Regeneration. Cambridge: Cambridge University Press, 2006, 72\u2013107.","DOI":"10.1017\/CBO9780511545115.005"},{"key":"2016082823222362000_22.5.574.37","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmn055"},{"key":"2016082823222362000_22.5.574.38","doi-asserted-by":"crossref","unstructured":"Cornwall GA , Lareyre JJ , Matusik RJ , Hinton BT, Orgebin-Crist MC . Gene expression and epididymal function. In: Robaire B , Hinton BT (ed). The epididymis: from molecules to clinical practice. New York: Klumer academic\/Plenum Publishers, 2002,169\u2013199.","DOI":"10.1007\/978-1-4615-0679-9_10"},{"key":"2016082823222362000_22.5.574.39","doi-asserted-by":"crossref","unstructured":"Cuasnicu P , Cohen D , Ellerman D , Busso D , DaRos V , Morgenfeld M. Changes in sperm proteins during epididymal maturation. In: Robaire BH , Hinton BT (ed). The epididymis From molecules to clinical pratice. New-York: Plenum Press, 2002, 389\u2013404.","DOI":"10.1007\/978-1-4615-0679-9_22"},{"key":"2016082823222362000_22.5.574.40","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2005.12.022"},{"key":"2016082823222362000_22.5.574.41","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2009.03.007"},{"key":"2016082823222362000_22.5.574.42","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.11.046"},{"key":"2016082823222362000_22.5.574.43","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.102.008177"},{"key":"2016082823222362000_22.5.574.44","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2014.74"},{"key":"2016082823222362000_22.5.574.45","doi-asserted-by":"publisher","DOI":"10.1021\/pr1001498"},{"key":"2016082823222362000_22.5.574.46","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.106.059246"},{"key":"2016082823222362000_22.5.574.47","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/978-1-4614-4711-5_11","article-title":"The blood-epididymis barrier and human male fertility","volume":"763","author":"Dube","year":"2012","journal-title":"Adv Exp Med Biol"},{"key":"2016082823222362000_22.5.574.48","doi-asserted-by":"publisher","DOI":"10.1111\/brv.12108"},{"key":"2016082823222362000_22.5.574.49","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M202325200"},{"key":"2016082823222362000_22.5.574.50","first-page":"381","article-title":"Advances in microsurgery and assisted reproduction for management of male infertility","volume":"1","author":"French","year":"2009","journal-title":"Front Biosci (Elite Ed)"},{"key":"2016082823222362000_22.5.574.51","doi-asserted-by":"publisher","DOI":"10.1021\/ac102075d"},{"key":"2016082823222362000_22.5.574.52","doi-asserted-by":"publisher","DOI":"10.1210\/mend-4-1-108"},{"key":"2016082823222362000_22.5.574.53","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.2011.01203.x"},{"key":"2016082823222362000_22.5.574.54","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.04.052"},{"key":"2016082823222362000_22.5.574.55","doi-asserted-by":"publisher","DOI":"10.1186\/2051-4190-23-8"},{"key":"2016082823222362000_22.5.574.56","doi-asserted-by":"crossref","first-page":"23S","DOI":"10.1002\/j.1939-4640.1994.tb01699.x","article-title":"Function of human epididymal spermatozoa","volume":"15","author":"Haidl","year":"1994","journal-title":"J Androl"},{"key":"2016082823222362000_22.5.574.57","doi-asserted-by":"publisher","DOI":"10.1677\/joe.1.06862"},{"key":"2016082823222362000_22.5.574.58","first-page":"106","article-title":"Secretion and endocytosis in the male reproductive tract: a role in sperm maturation","volume":"154","author":"Hermo","year":"1994","journal-title":"Int Rev Cytol"},{"key":"2016082823222362000_22.5.574.59","doi-asserted-by":"crossref","unstructured":"Hermo L , Robaire B . Epididymal cell types and their functions. In: Robaire B , Hinton BT (ed). The epididymis, from molecules to clinical practice. New York: Kluwer Academic\/Plenum Publishers, 2002, 81\u2013102.","DOI":"10.1007\/978-1-4615-0679-9_5"},{"key":"2016082823222362000_22.5.574.60","doi-asserted-by":"publisher","DOI":"10.1007\/BF00717000"},{"key":"2016082823222362000_22.5.574.61","doi-asserted-by":"crossref","unstructured":"Hess R . The efferent ductules: structure and functions. In: Robaire B , Hinton BT (ed). The epididymis From molecules to clinical practice. New York: Kluwer Academic\/Plenum, 2002, 49\u201380.","DOI":"10.1007\/978-1-4615-0679-9_4"},{"key":"2016082823222362000_22.5.574.62","doi-asserted-by":"publisher","DOI":"10.1530\/ror.0.0050084"},{"key":"2016082823222362000_22.5.574.63","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-7207(01)00412-9"},{"key":"2016082823222362000_22.5.574.64","doi-asserted-by":"publisher","DOI":"10.1038\/37352"},{"key":"2016082823222362000_22.5.574.65","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.110.012872"},{"key":"2016082823222362000_22.5.574.66","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0600291"},{"key":"2016082823222362000_22.5.574.67","doi-asserted-by":"crossref","unstructured":"Hinton BT , Cooper TG . The epididymis as a target for male contraceptive development. Handb Exp Pharmacol 2010:117\u2013137.","DOI":"10.1007\/978-3-642-02062-9_8"},{"key":"2016082823222362000_22.5.574.68","first-page":"47","article-title":"Testicular regulation of epididymal gene expression","volume":"53","author":"Hinton","year":"1998","journal-title":"J Reprod Fertil Suppl"},{"key":"2016082823222362000_22.5.574.69","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/1.5.515"},{"key":"2016082823222362000_22.5.574.70","doi-asserted-by":"publisher","DOI":"10.3109\/01485018308987492"},{"key":"2016082823222362000_22.5.574.71","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1997.8700"},{"key":"2016082823222362000_22.5.574.72","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.106.057323"},{"key":"2016082823222362000_22.5.574.73","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod14.4.371"},{"key":"2016082823222362000_22.5.574.74","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)46343-0"},{"key":"2016082823222362000_22.5.574.75","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod39.4.812"},{"key":"2016082823222362000_22.5.574.76","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.105.039719"},{"key":"2016082823222362000_22.5.574.77","first-page":"73","article-title":"Plasma membrane structure and remodelling during sperm maturation in the epididymis","volume":"53","author":"Jones","year":"1998","journal-title":"J Reprod Fertil Suppl"},{"key":"2016082823222362000_22.5.574.78","first-page":"163","article-title":"Evolution of the vertebrate epididymis","volume":"53","author":"Jones","year":"1998","journal-title":"J Reprod Fertil Suppl"},{"key":"2016082823222362000_22.5.574.79","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/j.1439-0272.1987.tb02321.x","article-title":"On the morphology of the transitional zones from the rete testis into the ductuli efferentes and from the ductuli efferentes into the ductus epididymidis. Investigations on the human testis and epididymis","volume":"19","author":"Jonte","year":"1987","journal-title":"Andrologia"},{"key":"2016082823222362000_22.5.574.80","first-page":"46","article-title":"Vasectomy and prostate cancer","volume":"6","author":"Khan","year":"2004","journal-title":"Rev Urology"},{"key":"2016082823222362000_22.5.574.81","first-page":"764","article-title":"Epididymis as a target for contraception","volume":"41","author":"Khole","year":"2003","journal-title":"Indian J Exptl Biol"},{"key":"2016082823222362000_22.5.574.82","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.102.011270"},{"key":"2016082823222362000_22.5.574.83","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61903-4"},{"key":"2016082823222362000_22.5.574.84","doi-asserted-by":"publisher","DOI":"10.1016\/S0074-7696(08)61567-3"},{"key":"2016082823222362000_22.5.574.85","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/8.8.695"},{"key":"2016082823222362000_22.5.574.86","doi-asserted-by":"crossref","unstructured":"Kirchhoff C . Specific gene expression in the human and non-human primate epididymis. In: Robaire B , Hinton BT (ed). The Epididymis From Molecules to Clinical Practice. New York: Kluwer Academic\/Plenum Publishers, 2002b.","DOI":"10.1007\/978-1-4615-0679-9_11"},{"key":"2016082823222362000_22.5.574.87","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod54.4.847"},{"key":"2016082823222362000_22.5.574.88","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2012.06.017"},{"key":"2016082823222362000_22.5.574.89","doi-asserted-by":"publisher","DOI":"10.1530\/rep.1.00964"},{"key":"2016082823222362000_22.5.574.90","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.04.040"},{"key":"2016082823222362000_22.5.574.91","doi-asserted-by":"crossref","first-page":"165","DOI":"10.4067\/S0716-97602001000300004","article-title":"Human epididymal proteins and sperm function during fertilization: un update","volume":"34","author":"Lasserre","year":"2001","journal-title":"Biol Res"},{"key":"2016082823222362000_22.5.574.92","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2013.08.010"},{"key":"2016082823222362000_22.5.574.93","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.109.009860"},{"key":"2016082823222362000_22.5.574.94","doi-asserted-by":"publisher","DOI":"10.1210\/en.140.7.3318"},{"key":"2016082823222362000_22.5.574.95","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gah087"},{"key":"2016082823222362000_22.5.574.96","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gal050"},{"key":"2016082823222362000_22.5.574.97","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod64.2.720"},{"key":"2016082823222362000_22.5.574.98","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.2004.tb02756.x"},{"key":"2016082823222362000_22.5.574.99","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msp284"},{"key":"2016082823222362000_22.5.574.100","doi-asserted-by":"crossref","unstructured":"Li J , Liu F , Liu X , Liu J , Zhu P , Wan F , Jin S , Wang W , Li N , Liu J et al . Mapping of the human testicular proteome and its relationship with that of the epididymis and spermatozoa. Mol Cell Proteomics 2011;10: M110 004630.","DOI":"10.1074\/mcp.M110.004630"},{"key":"2016082823222362000_22.5.574.101","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M110.001719"},{"key":"2016082823222362000_22.5.574.102","doi-asserted-by":"publisher","DOI":"10.1038\/aja.2009.59"},{"key":"2016082823222362000_22.5.574.103","unstructured":"Liu X , Jin SH , Liu XX , Wang WJ , Liu FJ . Proteome profiling of the sperm maturation milieu in the rhesus monkey (Macaca mulatta) epididymis. Reprod Fertil Dev 2014."},{"key":"2016082823222362000_22.5.574.104","doi-asserted-by":"publisher","DOI":"10.1111\/andr.12040"},{"key":"2016082823222362000_22.5.574.105","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3892\/mmr.2015.3435","article-title":"Indepth mapping of human testicular and epididymal proteins and their functional association with spermatozoa","volume":"12","author":"Liu","year":"2015","journal-title":"Mol Med Rep"},{"key":"2016082823222362000_22.5.574.106","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmu042"},{"key":"2016082823222362000_22.5.574.107","first-page":"21","article-title":"Male vaccine studied; shot not yet a reality","volume":"21","year":"2000","journal-title":"Contracept Technol Update"},{"key":"2016082823222362000_22.5.574.108","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2353(1996)9:5<337::AID-CA7>3.0.CO;2-9"},{"key":"2016082823222362000_22.5.574.109","doi-asserted-by":"publisher","DOI":"10.1016\/S0074-7696(00)99006-5"},{"key":"2016082823222362000_22.5.574.110","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.110.087452"},{"key":"2016082823222362000_22.5.574.111","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/11.suppl_3.103"},{"key":"2016082823222362000_22.5.574.112","doi-asserted-by":"publisher","DOI":"10.1530\/ror.0.0010054"},{"key":"2016082823222362000_22.5.574.113","doi-asserted-by":"publisher","DOI":"10.1002\/ajp.1350010215"},{"key":"2016082823222362000_22.5.574.114","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.12.053"},{"key":"2016082823222362000_22.5.574.115","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2013.10.006"},{"key":"2016082823222362000_22.5.574.116","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.304.6829.743"},{"key":"2016082823222362000_22.5.574.117","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0133449"},{"key":"2016082823222362000_22.5.574.118","doi-asserted-by":"publisher","DOI":"10.1038\/216816a0"},{"key":"2016082823222362000_22.5.574.119","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod50.3.516"},{"key":"2016082823222362000_22.5.574.120","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-0659-8_18"},{"key":"2016082823222362000_22.5.574.121","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.10.008"},{"key":"2016082823222362000_22.5.574.122","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-0659-8_26"},{"key":"2016082823222362000_22.5.574.123","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2012.07.003"},{"key":"2016082823222362000_22.5.574.124","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.02.021"},{"key":"2016082823222362000_22.5.574.125","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.105.049304"},{"key":"2016082823222362000_22.5.574.126","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.20751"},{"key":"2016082823222362000_22.5.574.127","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.111.014266"},{"key":"2016082823222362000_22.5.574.128","doi-asserted-by":"crossref","unstructured":"Robaire B , Hinton BT . The Epididymis. From Molecules to Clinical Practice . New York: Kluwer Academic\/Plenum Publishers, 2002","DOI":"10.1007\/978-1-4615-0679-9"},{"key":"2016082823222362000_22.5.574.129","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des360"},{"key":"2016082823222362000_22.5.574.130","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.1080260104"},{"key":"2016082823222362000_22.5.574.131","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.2004.tb02857.x"},{"key":"2016082823222362000_22.5.574.132","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.1990.tb01045.x"},{"key":"2016082823222362000_22.5.574.133","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/7.3.227"},{"key":"2016082823222362000_22.5.574.134","unstructured":"Schmidt S , Schoyman R , Stewart SH . Surgical approaches to male infertility. In: Hafez E (ed). Human semen and fertility regulation in men. St-Louis: CV Mosby Co., 1976, 476\u2013493."},{"key":"2016082823222362000_22.5.574.135","first-page":"102","article-title":"Epididymal causes of infertility pathogenesis and management","volume":"8","author":"Schoysman","year":"1981","journal-title":"Prog Reprod Biol"},{"key":"2016082823222362000_22.5.574.136","unstructured":"Schoysman R . Microsurgery of Male Infertility. Luglio: Finito di stampare dalla Arti Grafiche Siciliane-Palermo, 1994, 256."},{"key":"2016082823222362000_22.5.574.137","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)49528-2"},{"key":"2016082823222362000_22.5.574.138","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2001.02301.x"},{"key":"2016082823222362000_22.5.574.139","doi-asserted-by":"publisher","DOI":"10.1021\/pr900031r"},{"key":"2016082823222362000_22.5.574.140","doi-asserted-by":"crossref","unstructured":"Sharma U , Conine CC , Shea JM , Boskovic A , Derr AG , Bing XY , Belleannee C , Kucukural A , Serra RW , Sun F et al . Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. Science 2015; 10.1126\/Science.aad6780 .","DOI":"10.1126\/science.aad6780"},{"key":"2016082823222362000_22.5.574.141","doi-asserted-by":"publisher","DOI":"10.1159\/000363432"},{"key":"2016082823222362000_22.5.574.142","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2006.01.016"},{"key":"2016082823222362000_22.5.574.143","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2013.262"},{"key":"2016082823222362000_22.5.574.144","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1056\/NEJM197704142961527","article-title":"Vasectomy reversal","volume":"296","author":"Silber","year":"1977","journal-title":"N Eng J Med"},{"key":"2016082823222362000_22.5.574.145","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/S0022-5347(17)55415-4","article-title":"Ejaculatory duct obstruction","volume":"124","author":"Silber","year":"1980","journal-title":"J Urol"},{"key":"2016082823222362000_22.5.574.146","doi-asserted-by":"publisher","DOI":"10.1002\/micr.1920090409"},{"key":"2016082823222362000_22.5.574.147","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0022-5347(17)58440-2","article-title":"Microscopic vasovasostomy and spermatogenesis","volume":"117","author":"Silber","year":"1977","journal-title":"J Urol"},{"key":"2016082823222362000_22.5.574.148","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.110.012914"},{"key":"2016082823222362000_22.5.574.149","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gaq009"},{"key":"2016082823222362000_22.5.574.150","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0140-6736(78)92957-4","article-title":"Birth after the reimplantation of a human embryo","volume":"2","author":"Steptoe","year":"1978","journal-title":"Lancet"},{"key":"2016082823222362000_22.5.574.151","doi-asserted-by":"publisher","DOI":"10.1159\/000147201"},{"key":"2016082823222362000_22.5.574.152","unstructured":"Sullivan R. Interaction between sperm and epididymal secretory proteins. In Gagnon C (ed). The Male Gamete: From Basic to Clinical Applications. Vienna (IL, USA): Cache River Press, 1999, 130\u2013136."},{"key":"2016082823222362000_22.5.574.153","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.anireprosci.2004.05.007","article-title":"Male fertility markers, myth or reality","volume":"82\u201383","author":"Sullivan","year":"2004","journal-title":"Anim Reprod Sci"},{"key":"2016082823222362000_22.5.574.154","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.110.012575"},{"key":"2016082823222362000_22.5.574.155","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.10.070"},{"key":"2016082823222362000_22.5.574.156","doi-asserted-by":"publisher","DOI":"10.1016\/0303-7207(81)90017-4"},{"key":"2016082823222362000_22.5.574.157","first-page":"251","article-title":"Development and characterization of a model system for the study of epididymal physiology in man","volume":"87","author":"Tezon","year":"1982","journal-title":"Prog Clin Biol Res"},{"key":"2016082823222362000_22.5.574.158","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod32.3.591"},{"key":"2016082823222362000_22.5.574.159","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod32.3.584"},{"key":"2016082823222362000_22.5.574.160","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.107.066449"},{"key":"2016082823222362000_22.5.574.161","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/den181"},{"key":"2016082823222362000_22.5.574.162","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gam051"},{"key":"2016082823222362000_22.5.574.163","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2005.12.025"},{"key":"2016082823222362000_22.5.574.164","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/j.1939-4640.1995.tb00532.x","article-title":"On the epididymis and its role in the development of the fertile ejaculate","volume":"16","author":"Turner","year":"1995","journal-title":"J Androl"},{"key":"2016082823222362000_22.5.574.165","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.107.004119"},{"key":"2016082823222362000_22.5.574.166","doi-asserted-by":"publisher","DOI":"10.1530\/rep.0.1250871"},{"key":"2016082823222362000_22.5.574.167","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0550323"},{"key":"2016082823222362000_22.5.574.168","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1002\/j.1939-4640.1990.tb00170.x","article-title":"Fluid movement in the lumen of the rat epididymis: effect of vasectomy and subsequent vasovasostomy","volume":"11","author":"Turner","year":"1990","journal-title":"J Androl"},{"key":"2016082823222362000_22.5.574.169","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.106.059493"},{"key":"2016082823222362000_22.5.574.170","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-7262.2007.00302.x"},{"key":"2016082823222362000_22.5.574.171","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/j.1939-4640.1999.tb02520.x","article-title":"Obstruction of the vas deferens alters protein secretion by the rat caput epididymidal epithelium in vivo","volume":"20","author":"Turner","year":"1999","journal-title":"J Androl"},{"key":"2016082823222362000_22.5.574.172","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/j.1939-4640.2000.tb02106.x","article-title":"Postvasectomy alterations in protein synthesis and secretion in the rat caput epididymidis are not repaired after vasovasostomy","volume":"21","author":"Turner","year":"2000","journal-title":"J Androl"},{"key":"2016082823222362000_22.5.574.173","doi-asserted-by":"publisher","DOI":"10.1002\/pros.10255"},{"key":"2016082823222362000_22.5.574.174","doi-asserted-by":"crossref","first-page":"S194","DOI":"10.1016\/j.fertnstert.2004.05.052","article-title":"Vasectomy reversal","volume":"82","year":"2004","journal-title":"Fertil Steril"},{"key":"2016082823222362000_22.5.574.175","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/j.1939-4640.1996.tb00583.x","article-title":"The mRNAs for the steroid 5 alpha-reductase isozymes, types 1 and 2, are differentially regulated in the rat epididymis","volume":"17","author":"Viger","year":"1996","journal-title":"J Androl"},{"key":"2016082823222362000_22.5.574.176","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2012.12.008"},{"key":"2016082823222362000_22.5.574.177","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2012.06.021"},{"key":"2016082823222362000_22.5.574.178","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001910306"},{"key":"2016082823222362000_22.5.574.179","first-page":"137","article-title":"Receptor tyrosine kinase c-ros knockout mice as a model for the study of epididymal regulation of sperm function","volume":"53","author":"Yeung","year":"1998","journal-title":"J Reprod Fertil Suppl"},{"key":"2016082823222362000_22.5.574.180","doi-asserted-by":"publisher","DOI":"10.1093\/abbs\/gmp116"},{"key":"2016082823222362000_22.5.574.181","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2005.12.041"}],"container-title":["Human Reproduction Update"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humupd\/article-pdf\/22\/5\/574\/6755285\/dmw015.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T17:28:33Z","timestamp":1718645313000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humupd\/article-lookup\/doi\/10.1093\/humupd\/dmw015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,15]]},"references-count":181,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2016,8,26]]},"published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1093\/humupd\/dmw015"],"URL":"https:\/\/doi.org\/10.1093\/humupd\/dmw015","relation":{},"ISSN":["1355-4786","1460-2369"],"issn-type":[{"value":"1355-4786","type":"print"},{"value":"1460-2369","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,15]]}}}