{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:35:13Z","timestamp":1790832913621,"version":"4.1.0"},"reference-count":84,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum. Reprod. Update"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1093\/humupd\/dmw019","type":"journal-article","created":{"date-parts":[[2016,6,21]],"date-time":"2016-06-21T02:28:34Z","timestamp":1466476114000},"page":"775-790","source":"Crossref","is-referenced-by-count":108,"title":["The impact of thyroid autoimmunity on IVF\/ICSI outcome: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"22","author":[{"given":"Andrea","family":"Busnelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio","family":"Paffoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Fedele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgardo","family":"Somigliana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,6,20]]},"reference":[{"key":"2016110404421354000_22.6.775.1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-0141"},{"key":"2016110404421354000_22.6.775.2","doi-asserted-by":"publisher","DOI":"10.1080\/09513590701259542"},{"key":"2016110404421354000_22.6.775.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2013.11.003"},{"key":"2016110404421354000_22.6.775.4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1993.tb01748.x"},{"key":"2016110404421354000_22.6.775.5","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dml034"},{"key":"2016110404421354000_22.6.775.6","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2014.0088"},{"key":"2016110404421354000_22.6.775.7","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-15-0151"},{"key":"2016110404421354000_22.6.775.8","doi-asserted-by":"publisher","DOI":"10.4158\/EP15933.OR"},{"key":"2016110404421354000_22.6.775.9","doi-asserted-by":"publisher","DOI":"10.1210\/en.140.4.1783"},{"key":"2016110404421354000_22.6.775.10","doi-asserted-by":"publisher","DOI":"10.1111\/cen.12220"},{"key":"2016110404421354000_22.6.775.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2010.03974.x"},{"key":"2016110404421354000_22.6.775.12","doi-asserted-by":"publisher","DOI":"10.5653\/cerm.2015.42.4.131"},{"key":"2016110404421354000_22.6.775.13","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmu028"},{"key":"2016110404421354000_22.6.775.14","first-page":"72","article-title":"Functional lymphocyte subset assessment of the Th1\/Th2 profile in patients with autoimmune thyroiditis by flowcytometric analysis of peripheral lymphocytes","volume":"18","author":"Colin","year":"2004","journal-title":"J Biol Regul Homeost Agents"},{"key":"2016110404421354000_22.6.775.15","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(86)90046-2"},{"key":"2016110404421354000_22.6.775.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2006.04.004"},{"key":"2016110404421354000_22.6.775.17","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmt062"},{"key":"2016110404421354000_22.6.775.18","doi-asserted-by":"crossref","unstructured":"Egger M , Davey SG , Altman DG. Systematic Reviews in Health Care: Meta-Analysis in Context. Part IV, Chapters 15\u201316, 2nd edn. London: BMJ Publishing Group, 2001, 285\u2013312.","DOI":"10.1002\/9780470693926"},{"key":"2016110404421354000_22.6.775.19","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7121.1533"},{"key":"2016110404421354000_22.6.775.20","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/"},{"key":"2016110404421354000_22.6.775.21","doi-asserted-by":"publisher","DOI":"10.1177\/1933719115608000"},{"key":"2016110404421354000_22.6.775.22","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0834"},{"key":"2016110404421354000_22.6.775.23","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-73-2-421"},{"key":"2016110404421354000_22.6.775.24","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2000.10.871"},{"key":"2016110404421354000_22.6.775.25","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1005"},{"key":"2016110404421354000_22.6.775.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.12.023"},{"key":"2016110404421354000_22.6.775.27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2006.00438.x"},{"key":"2016110404421354000_22.6.775.28","doi-asserted-by":"publisher","DOI":"10.3803\/EnM.2013.28.3.221"},{"key":"2016110404421354000_22.6.775.29","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7414.557"},{"key":"2016110404421354000_22.6.775.30","doi-asserted-by":"crossref","unstructured":"Higgins JPT , Green S (eds). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011, published as textbook by Wiley-Blackwell in September 2008. Available from www.cochrane-handbook.org.","DOI":"10.1002\/9780470712184"},{"key":"2016110404421354000_22.6.775.31","doi-asserted-by":"publisher","DOI":"10.1210\/er.18.1.107"},{"key":"2016110404421354000_22.6.775.32","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1500363"},{"key":"2016110404421354000_22.6.775.33","doi-asserted-by":"publisher","DOI":"10.14310\/horm.2002.1210"},{"key":"2016110404421354000_22.6.775.34","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2013.07.002"},{"key":"2016110404421354000_22.6.775.35","doi-asserted-by":"publisher","DOI":"10.1080\/09513590802531112"},{"key":"2016110404421354000_22.6.775.36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.1998.tb00380.x"},{"key":"2016110404421354000_22.6.775.37","doi-asserted-by":"publisher","DOI":"10.1586\/17446651.3.2.127"},{"key":"2016110404421354000_22.6.775.38","doi-asserted-by":"publisher","DOI":"10.1210\/er.2009-0041"},{"key":"2016110404421354000_22.6.775.39","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(99)00091-6"},{"key":"2016110404421354000_22.6.775.40","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmp036"},{"key":"2016110404421354000_22.6.775.41","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12615"},{"key":"2016110404421354000_22.6.775.42","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-015-0377-5"},{"key":"2016110404421354000_22.6.775.43","doi-asserted-by":"publisher","DOI":"10.1530\/acta.0.1250058"},{"key":"2016110404421354000_22.6.775.44","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2008.03338.x"},{"key":"2016110404421354000_22.6.775.45","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.06.020"},{"key":"2016110404421354000_22.6.775.46","doi-asserted-by":"publisher","DOI":"10.1159\/000357193"},{"key":"2016110404421354000_22.6.775.47","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-151-4-200908180-00135"},{"key":"2016110404421354000_22.6.775.48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2010.00961.x"},{"key":"2016110404421354000_22.6.775.49","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(98)00394-X"},{"key":"2016110404421354000_22.6.775.50","doi-asserted-by":"publisher","DOI":"10.1007\/BF03346432"},{"key":"2016110404421354000_22.6.775.51","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.08.127"},{"key":"2016110404421354000_22.6.775.52","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh843"},{"key":"2016110404421354000_22.6.775.53","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-1603"},{"key":"2016110404421354000_22.6.775.54","doi-asserted-by":"publisher","DOI":"10.1007\/BF03347388"},{"key":"2016110404421354000_22.6.775.55","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6874-3-2"},{"key":"2016110404421354000_22.6.775.56","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7251.1708"},{"key":"2016110404421354000_22.6.775.57","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der044"},{"key":"2016110404421354000_22.6.775.58","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dev089"},{"key":"2016110404421354000_22.6.775.59","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030268"},{"key":"2016110404421354000_22.6.775.60","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0105"},{"key":"2016110404421354000_22.6.775.61","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2007.02752.x"},{"key":"2016110404421354000_22.6.775.62","doi-asserted-by":"publisher","DOI":"10.1038\/ncpendmet0846"},{"key":"2016110404421354000_22.6.775.63","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.05.028"},{"key":"2016110404421354000_22.6.775.64","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1500751"},{"key":"2016110404421354000_22.6.775.65","first-page":"7","article-title":"A retrospective study on IVF outcome in euthyroid patients with anti-thyroid antibodies: effects of levothyroxine, acetyl-salicylic acid and prednisolone adjuvant treatments","volume":"27","author":"Revelli","year":"2009","journal-title":"Reprod Biol Endocrinol"},{"key":"2016110404421354000_22.6.775.66","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2013.212"},{"key":"2016110404421354000_22.6.775.67","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)57355-5"},{"key":"2016110404421354000_22.6.775.68","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2004.03.007"},{"key":"2016110404421354000_22.6.775.69","unstructured":"StataCorp . Commands metan, metafunnel, metabias. Stata: Release 13. Statistical Software. College Station, TX: StataCorp LP, 2013."},{"key":"2016110404421354000_22.6.775.70","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2003.01862.x"},{"key":"2016110404421354000_22.6.775.71","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-13-0790"},{"key":"2016110404421354000_22.6.775.72","first-page":"342","article-title":"Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence","volume":"9","author":"Thangaratinam","year":"2011","journal-title":"BMJ"},{"key":"2016110404421354000_22.6.775.73","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-09-0850"},{"key":"2016110404421354000_22.6.775.74","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2011.11.014"},{"key":"2016110404421354000_22.6.775.75","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0562"},{"key":"2016110404421354000_22.6.775.76","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr024"},{"key":"2016110404421354000_22.6.775.77","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dms007"},{"key":"2016110404421354000_22.6.775.78","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmv004"},{"key":"2016110404421354000_22.6.775.79","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)55974-3"},{"key":"2016110404421354000_22.6.775.80","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2014.97"},{"key":"2016110404421354000_22.6.775.81","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-015-0041-0"},{"key":"2016110404421354000_22.6.775.82","unstructured":"Wells GA , Shea B , O'Connell D , Peterson J , Welch V , Tugwell P. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. 3rd Symposium on Systematic Reviews: Beyond the Basics, Oxford, UK, 2000. Available at: http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.htm."},{"key":"2016110404421354000_22.6.775.83","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.09.009"},{"key":"2016110404421354000_22.6.775.84","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.3467"}],"container-title":["Human Reproduction Update"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/humupd\/article-pdf\/22\/6\/775\/8508085\/dmw019.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:42:30Z","timestamp":1568076150000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/humupd\/article-lookup\/doi\/10.1093\/humupd\/dmw019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,20]]},"references-count":84,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2016,11,4]]},"published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1093\/humupd\/dmw019"],"URL":"https:\/\/doi.org\/10.1093\/humupd\/dmw019","relation":{},"ISSN":["1355-4786","1460-2369"],"issn-type":[{"value":"1355-4786","type":"print"},{"value":"1460-2369","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,20]]}}}