{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T17:23:48Z","timestamp":1768584228446,"version":"3.49.0"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"Supplement_2","license":[{"start":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T00:00:00Z","timestamp":1640822400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The Crohn\u2019s disease (CD) phenotype differs between Asian and Western countries and may affect disease management, including decisions on surgery. This study aimed to compare the indications, postoperative management, and long-term prognosis after ileocecal resection (ICR) in Hong Kong (HK) and the Netherlands (NL).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>CD patients with primary ICR between 2000 and 2019 were included. The endpoints were endoscopic (Rutgeerts score \u2265i2b and\/or radiologic recurrence), clinical (start or switch of inflammatory bowel disease medication), and surgical recurrences. Cumulative incidences of recurrence were estimated with a Bayesian multivariable proportional hazards model.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Eighty HK and 822 NL patients were included. The most common indication for ICR was penetrating disease (HK: 32.5%, NL: 22.5%) in HK vs stricturing disease (HK: 32.5%, NL: 48.8%) in the NL (P &amp;lt; .001). Postoperative prophylaxis was prescribed to 65 (81.3%) HK patients (28 [35.0%] aminosalicylates [5-aminosalicylic acid]; 30 [37.5%] immunomodulators; 0 biologicals) vs 388 (47.1%) NL patients (67 [8.2%] 5-aminosalicylic acid; 187 [22.8%] immunomodulators; 69 [8.4%] biologicals; 50 [6.1%] combination therapy) (P &amp;lt; .001). Endoscopic or radiologic evaluation within 18 months was performed in 36.3% HK vs 64.1% NL (P &amp;lt; .001) patients. No differences between both populations were observed for endoscopic (hazard ratio [HR], 0.53; 95% confidence interval [CI], 0.24-1.21), clinical (HR, 0.91; 95% CI, 0.62-1.32), or surgical (HR, 0.61; 95% CI, 0.31-1.13) recurrence risks.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The main indication for ICR in CD patients is penetrating disease in HK patients and stricturing disease in NL patients. Although considerable pre- and postoperative management differences were observed between the two geographical areas, the long-term prognosis after ICR is similar.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ibd\/izab316","type":"journal-article","created":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T22:31:54Z","timestamp":1640903514000},"page":"S16-S24","source":"Crossref","is-referenced-by-count":9,"title":["Indications, Postoperative Management, and Long-term Prognosis of Crohn\u2019s Disease After Ileocecal Resection: A Multicenter Study Comparing the East and West"],"prefix":"10.1093","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6769-4604","authenticated-orcid":false,"given":"Jeanine H C","family":"Arkenbosch","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus University Medical Center , Rotterdam , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyce W Y","family":"Mak","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, Chinese University of Hong Kong , Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacky C L","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, Chinese University of Hong Kong , Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelien M J","family":"Beelen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus University Medical Center , Rotterdam , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole S","family":"Erler","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Erasmus University Medical Center , Rotterdam , the Netherlands"},{"name":"Department of Epidemiology, Erasmus University Medical Center , Rotterdam , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Hoentjen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Radboud University Medical Center , Nijmegen , the Netherlands"},{"name":"Division of Gastroenterology, University of Alberta , Edmonton , AB, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander G L","family":"Bodelier","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Amphia Hospital , Breda , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard","family":"Dijkstra","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Medical Center Groningen , Groningen , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari\u00eblle","family":"Romberg-Camps","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Zuyderland Medical Center , Sittard-Geleen , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanne K H","family":"de Boer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, AGEM Research Institute , Amsterdam , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurents P S","family":"Stassen","sequence":"additional","affiliation":[{"name":"Department of Surgery, Maastricht University Medical Center , Maastricht , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9353-5431","authenticated-orcid":false,"given":"Andrea E","family":"van der Meulen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Leiden University Medical Center , Leiden , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"West","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Franciscus Gasthuis and Vlietland , Rotterdam , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oddeke","family":"van Ruler","sequence":"additional","affiliation":[{"name":"Department of Surgery, IJsselland Hospital , Capelle aan den IJssel , the Netherlands"},{"name":"Department of Surgery, Erasmus University Medical Center , Rotterdam , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christien Janneke","family":"van der Woude","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus University Medical Center , Rotterdam , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siew C","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, Chinese University of Hong Kong , Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annemarie C","family":"de Vries","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus University Medical Center , Rotterdam , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,12,30]]},"reference":[{"key":"2023112816105911400_CIT0001","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1016\/S0140-6736(17)32448-0","article-title":"Worldwide incidence and \u00adprevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based 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Hepatol."},{"key":"2023112816105911400_CIT0007","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1016\/j.cgh.2020.01.028","article-title":"Changing global epidemiology of inflammatory bowel diseases: sustaining health care delivery into the 21st Century.","volume":"18","author":"Ananthakrishnan","year":"2020","journal-title":"Clin Gastroenterol Hepatol."},{"key":"2023112816105911400_CIT0008","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/jgh.15185","article-title":"Asian Organization for Crohn\u2019s and Colitis and Asia Pacific Association of Gastroenterology practice recommendations for medical management and monitoring of inflammatory bowel disease in Asia.","volume":"36","author":"Ran","year":"2021","journal-title":"J Gastroenterol Hepatol."},{"key":"2023112816105911400_CIT0009","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/SLA.0000000000003395","article-title":"Decreasing trends in intestinal resection and re-resection in crohn\u2019s 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